1,061 research outputs found
Aprendizaje profundo del concepto “volumen de líquido desplazado” a través de la resolución de problemas ambientales en el marco del ahorro y uso eficiente del agua
El presente estudio surge de la necesidad de transformar la enseñanza, profundizar en el aprendizaje y desarrollar habilidades de pensamiento, bajo un proceso de ambientalización curricular escolar que considere la dimensión ambiental como eje articulador para la enseñanza de las ciencias. Desde esta perspectiva, la investigación se inscribe en el Macroproyecto “Tecnologías para el ahorro y uso eficiente del agua” de la línea de profundización de la Maestría en Ciencias Ambientales. Es un informe de corte descriptivo (cuantitativo) sobre el desarrollo de habilidades del pensamiento como la argumentación y la resolución de problemas, bajo un enfoque de aprendizaje profundo, en estudiantes de sexto grado de la Institución Educativa Agustín Nieto Caballero del municipio de Dosquebradas. Para la intervención en el aula, se diseñó una secuencia didáctica (bajo el ciclo de aprendizaje constructivista) sobre el concepto de volumen de líquido desplazado, que se articuló con un modelo de enseñanza por resolución de situaciones problémicas ambientales en el contexto del ahorro y uso eficiente del agua
Aprendizaje profundo del concepto “volumen de líquido desplazado” a través de la resolución de problemas ambientales en el marco del ahorro y uso eficiente del agua
El presente estudio surge de la necesidad de transformar la enseñanza, profundizar en el aprendizaje y desarrollar habilidades de pensamiento, bajo un proceso de ambientalización curricular escolar que considere la dimensión ambiental como eje articulador para la enseñanza de las ciencias. Desde esta perspectiva, la investigación se inscribe en el Macroproyecto “Tecnologías para el ahorro y uso eficiente del agua” de la línea de profundización de la Maestría en Ciencias Ambientales. Es un informe de corte descriptivo (cuantitativo) sobre el desarrollo de habilidades del pensamiento como la argumentación y la resolución de problemas, bajo un enfoque de aprendizaje profundo, en estudiantes de sexto grado de la Institución Educativa Agustín Nieto Caballero del municipio de Dosquebradas. Para la intervención en el aula, se diseñó una secuencia didáctica (bajo el ciclo de aprendizaje constructivista) sobre el concepto de volumen de líquido desplazado, que se articuló con un modelo de enseñanza por resolución de situaciones problémicas ambientales en el contexto del ahorro y uso eficiente del agua
Remuneration Sensitivity Analysis in Prosumer and Aggregator Strategies by Controlling Electric Vehicle Chargers
The efficient use of energy resources is profoundly changing power grid regulation and policy. New forms of power generation coupled with storage and the presence of new, increasingly flexible loads such as electric vehicles enable the development of multi-agent planning systems based on new forms of interaction. For instance, consumers can take advantage of flexibility by interacting directly with the grid or through aggregators that bridge the gap between these end-users and traditional centralised markets. This paper aims to provide insight into the benefits for aggregators and end-users from a financial perspective by proposing a methodology that can be applied to different scenarios. End-users may provide flexibility services related to private vehicle charging stations or battery storage systems. The paper will analyse different remuneration levels for end-users by highlighting the most beneficial scenarios for aggregators and end-users and providing evidence on potential conflict of interests. The numerical results show that some consumers may benefit more from aggregation. This is because if taken individually, consumption habits do not allow the same flexibility when considering clusters of consumers with different behaviour. It is also shown that there are cases in which consumers do not seem to benefit from the presence of intermediate parties. We provide extensive numerical results to gain insight for better decision making
Soliton defects in one-gap periodic system and exotic supersymmetry
By applying Darboux-Crum transformations to the quantum one-gap Lame system,
we introduce an arbitrary countable number of bound states into forbidden
bands. The perturbed potentials are reflectionless and contain two types of
soliton defects in the periodic background. The bound states with finite number
of nodes are supported in the lower forbidden band by the periodicity defects
of the potential well type, while the pulse type bound states in the gap have
infinite number of nodes and are trapped by defects of the compression
modulations nature. We investigate the exotic nonlinear N=4 supersymmetric
structure in such paired Schrodinger systems, which extends an ordinary N=2
supersymmetry and involves two bosonic generators composed from Lax-Novikov
integrals of the subsystems. One of the bosonic integrals has a nature of a
central charge, and allows us to liaise the obtained systems with the
stationary equations of the Korteweg-de Vries and modified Korteweg-de Vries
hierarchies. This exotic supersymmetry opens the way for the construction of
self-consistent condensates based on the Bogoliubov-de Gennes equations and
associated with them new solutions to the Gross-Neveu model. They correspond to
the kink or kink-antikink defects of the crystalline background in dependence
on whether the exotic supersymmetry is unbroken or spontaneously broken.Comment: 44 pages, 11 figures; comments and refs added, version to appear in
Phys. Rev.
Programación Óptima de Cargas Eléctricas Flexibles a Nivel Residencial en Tiempos de Covid-19
A mathematical model for flexible electrical loads and energy storage system scheduling is presented in this paper, leveraged by the hourly rates according to Resolution CREG 015/2018 and analyzed at the residential sector in the context of new demand curves resulting from measures against the COVID-19 pandemic. Three mathematical optimization models are proposed, aiming to find the lowest billing cost for the end-user through flexible load characteristics and seeking optimization through mixed-integer linear programming models. For the calculation of hourly rates, the mathematical formulation described in resolution CREG 015 is implemented and hourly rates are obtained in three different levels following a logic similar to the demand response schemes called Time of Use.
The results obtained show that a demand response program with hourly rates effectively introduces an economic incentive during the evaluated period, through the possibility of modifying consumption patterns that reduce the payment of the electricity bill. The proposed model of energy demand through scheduling selected flexible loads model and the opportunity to use the energy stored in electric vehicles generates economic benefits for the user by minimizing the cost of energy during the teleworking period in COVID-19 pandemic.En este trabajo se presenta un modelo matemático de programación de cargas eléctricas flexibles y sistemas de almacenamiento de energía, apalancado por la estructuración de cargos horarios de la Resolución CREG 015 del 2018 y analizado en el sector residencial en el contexto de nuevas curvas de demanda resultantes de las medidas en contra de la pandemia del COVID-19. Se plantean tres modelos de optimización matemática en los cuales se busca el menor costo de facturación para el usuario final a través de las características flexibles de la carga. Se implementa para el cálculo de cargos horarios la formulación matemática descrita en la resolución CREG 015 y se obtienen tarifas horarias en tres niveles diferentes siguiendo una lógica similar a los esquemas de respuesta de la demanda denominados Time of Use.
Los resultados obtenidos permiten evidenciar que un programa de respuesta de la demanda por cargos horarios efectivamente introduce un incentivo económico durante el periodo evaluado, a través de la posibilidad de la modificación de patrones de consumo que redundan en disminución del pago de factura de electricidad. El modelo propuesto de demanda de energía por medio de programación de cargas flexibles seleccionadas y la oportunidad de uso de la energía almacenada por los vehículos eléctricos, genera beneficios económicos para el usuario minimizando el costo de energía consumida diaria durante el periodo de teletrabajo en tiempos de COVID-19
Evidence of blood stage efficacy with a virosomal malaria vaccine in a Phase IIa clinical trial
Background
Previous research indicates that a combination vaccine targeting different stages of the malaria life cycle is likely to provide the most effective malaria vaccine. This trial was the first to combine two existing vaccination strategies to produce a vaccine that induces immune responses to both the pre-erythrocytic and blood stages of the P. falciparum life cycle.
Methods
This was a Phase I/IIa study of a new combination malaria vaccine FFM ME-TRAP+PEV3A. PEV3A includes peptides from both the pre-erythrocytic circumsporozoite protein and the blood-stage antigen AMA-1. This study was conducted at the Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK. The participants were healthy, malaria naïve volunteers, from Oxford. The interventions were vaccination with PEV3A alone, or PEV3A+FFM ME-TRAP. The main outcome measure was protection from malaria in a sporozoite challenge model. Other outcomes included measures of parasite specific immune responses induced by either vaccine; and safety, assessed by collection of adverse event data.
Results
We observed evidence of blood stage immunity in PEV3A vaccinated volunteers, but no volunteers were completely protected from malaria. PEV3A induced high antibody titres, and antibodies bound parasites in immunofluorescence assays. Moreover, we observed boosting of the vaccine-induced immune response by sporozoite challenge. Immune responses induced by FFM ME-TRAP were unexpectedly low. The vaccines were safe, with comparable side effect profiles to previous trials. Although there was no sterile protection two major observations support an effect of the vaccine-induced response on blood stage parasites: (i) Lower rates of parasite growth were observed in volunteers vaccinated with PEV3A compared to unvaccinated controls (p = 0.012), and this was reflected in the PCR results from PEV3A vaccinated volunteers. These showed early control of parasitaemia by some volunteers in this group. One volunteer, who received PEV3A alone, was diagnosed very late, on day 20 compared to an average of 11.8 days in unvaccinated controls. (ii). Morphologically abnormal parasites were present in the blood of all (n = 24) PEV3A vaccinated volunteers, and in only 2/6 controls (p = 0.001). We describe evidence of vaccine-induced blood stage efficacy for the first time in a sporozoite challenge study
Diet and habitat as determinants of intestine length in fishes
Fish biologists have long assumed a link between intestinal length and diet, and relative gut length or Zihler’s index are often used to classify species into trophic groups. This has been done for specific fish taxa or specific ecosystems, but not for a global fish dataset. Here, we assess these relationships across a dataset of 468 fish species (254 marine, 191 freshwater, and 23 occupy both habitats) in relation to body mass and fish length. Herbivores had significantly relatively stouter bodies and longer intestines than omni- and faunivores. Among faunivores, corallivores had longer intestines than invertivores, with piscivores having the shortest. There were no detectable differences between herbivore groups, possibly due to insufficient understanding of herbivorous fish diets. We propose that reasons for long intestines in fish include (i) difficult-to-digest items that require a symbiotic microbiome, and (ii) the dilution of easily digestible compounds with indigestible material (e.g., sand, wood, exoskeleton). Intestinal indices differed significantly between dietary groups, but there was substantial group overlap. Counter-intuitively, in the largest dataset, marine species had significantly shorter intestines than freshwater fish. These results put fish together with mammals as vertebrate taxa with clear convergence in intestine length in association with trophic level, in contrast to reptiles and birds, even if the peculiar feeding ecology of herbivorous fish is probably more varied than that of mammalian herbivores
Estratégias para Disminuir las Cargas de Residuos Sólidos Dispuestos en los Rellenos Sanitarios del Departamento de Antioquia Como Fomento de la Responsabilidad Socioambiental.
Conocer las diferentes estrategias utilizadas a nivel local, nacional e internacional que son usadas para disminuir las cargas de residuos sólidos que son dispuestos en los rellenos sanitarios, con el fin de brindar la posibilidad de proponer opciones sustentables para su aprovechamiento, ya que los residuos de cualquier localidad deberían ser manejados de forma apropiada y de esta menara convertirse en insumos de algún otro proceso. El objetivo de esta investigación fue identificar dichas estrategias, describir el manejo que se le da a los residuos sólidos en otros países y que son dispuestas en rellenos sanitarios y plantear las posibles metodologías adecuadas en la implementación de estrategias para la disminución de residuos sólidos que contribuyan a mejorar las condiciones ambientales, físicas, económicas y sociales de las zonas donde esta ubicados los rellenos sanitarios.Corporación Universitaria Minuto de Dio
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