Development stages of navigation inside TMA from its traditional procedures to P-RNAV.

Bakalářská práce se zabývá vývojem letecké navigace v koncové oblasti (TMA). Popisuje terminálový prostor v okolí letiště a vyjmenovává současné druhy přiblížení. Vysvětluje také koncept PBN organizace ICAO a srovnává jeho zavedení na ranvejích v Evropě i ve světě. Poslední kapitola odhaluje budoucí použití leteckých navigačních zařízení v prostoru TMA a při přiblížení a přistání v Evropě.This bachelor thesis explains development of air navigation inside the terminal maneuvering area. It describes terminal maneuvering area in vicinity of airport and lists current types of approaches. It explains also the ICAO PBN concept and compares its introduction in Europe and in the world. Last chapter reveals future use of air navigation facilities in terminal maneuvering area and during approach and landing in Europe.

Glacial cycles promote greater dispersal, which can help explain larger clutch sizes, in north temperate birds

Earth’s glacial history and patterns in the life history traits of the planet’s avifauna suggest the following interpretations of how recent geological history has affected these key characteristics of the biota: 1) Increased colonizing ability has been an important advantage of increased dispersal, and life history strategies are better categorized by dispersive colonizing ability than by their intrinsic growth rates; 2) Birds of the North Temperate Zone show a greater tendency to disperse, and they disperse farther, than tropical or south temperate birds; 3) Habitat changes associated with glacial advance and retreat selected for high dispersal ability, particularly in the North; and 4) Selection for greater dispersal throughout the unstable Pleistocene has also resulted in other well-recognized life history contrasts, especially larger clutch sizes in birds of North Temperate areas

Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease

Background - Therapeutic neovascularization may constitute an important strategy to salvage tissue from critical ischemia. Circulating bone marrow–derived endothelial progenitor cells (EPCs) were shown to augment the neovascularization of ischemic tissue. In addition to lipid-lowering activity, hydroxymethyl glutaryl coenzyme A reductase inhibitors (statins) reportedly promote the neovascularization of ischemic tissue in normocholesterolemic animals. Methods and Results - Fifteen patients with angiographically documented stable coronary artery disease (CAD) were prospectively treated with 40 mg of atorvastatin per day for 4 weeks. Before and weekly after the initiation of statin therapy, EPCs were isolated from peripheral blood and counted. In addition, the number of hematopoietic precursor cells positive for CD34, CD133, and CD34/kinase insert domain receptor was analyzed. Statin treatment of patients with stable CAD was associated with an '1.5-fold increase in the number of circulating EPCs by 1 week after initiation of treatment; this was followed by sustained increased levels to '3-fold throughout the 4-week study period. Moreover, the number of CD34/kinase insert domain receptor–positive hematopoietic progenitor cells was significantly augmented after 4 weeks of therapy. Atorvastatin treatment increased the further functional activity of EPCs, as assessed by their migratory capacity

Autonomous, connected, electric shared vehicles (ACES) and public finance: An explorative analysis

This paper discusses the implications of autonomous-connected-electric-shared vehicles (ACES) for public finance, which have so far been widely ignored in the literature. In OECD countries, 5-12% of federal and up to 30% of local tax revenues are currently collected from fuel and vehicle taxation. The diffusion of ACES will significantly reduce these important sources of government revenues and affect transport-related government expenditures, unless additional policies are introduced to align the new technological context with the tax revenue requirements. We argue that the realization of socioeconomic benefits of ACES depends on the implementation of tailored public finance policies, which can take advantage of the increase in data availability from the further digitalization of transportation systems. In particular, the introduction of road tolls in line with "user Pays" and "polluter Pays" principles will become more feasible for policy. Moreover, innovation in taxation schemes to fit the changing technological circumstances may alter the relative importance of levels of governance in transport policy making, likely shifting power towards local, in particular urban, governmental levels. We finally argue that, given the risk of path-dependencies and lock-in to sub-optimal public finance regimes if policies are implemented late, further research and near-term policy actions taken during the diffusion process of ACES are required