Gender dynamics in the workplace: Coaching strategies for women in the organization

Despite significant progress in promoting gender justice in the workplace, gender dynamics further affect women's career opportunities and advancement. This article highlights coaching strategies to help female clients navigate these dynamics and advance their careers. Drawing on research and best practices, this article builds on the recognition and understanding of gender differences while avoiding harmful stereotypes. In this research, women identified studies related to the areas of coaching strategies in the workplace by using the methods of review systems and by searching in databases and specifying indicators to get the opinion of the input researches, we analyzed the data using a narrative synthesis. The studies included in this review used different coaching interventions, including one-on-one coaching, group coaching, and mentoring programs. Several studies have focused on the impact of mentoring on gender-based biases, including perceptions of women in leadership positions and the impact of mentoring on men's attitudes toward female leaders. This systematic literature review highlights the effectiveness of coaching in addressing gender-based biases, identifying and overcoming barriers to advancement, and developing effective communication and leadership skills for women in the workplace. In this paper, we conclude that while progress toward gender equity remains a struggle, mentoring can play a critical role in helping women reach their full potential in the workplace

Lipid Lowering Effects of Aqueous Saffron Extract in Diabetic Rats

Introduction: Diabetes mellitus is one of the most common non-communicable and chronic diseases. The present study aimed to review the lipid lowering effects of aqueous saffron extract in diabetic rats. Methods: Sixty diabetic rats with fasting blood glucose of over 300 mg/dl were selected as sample and divided in two groups of saffron extract and control. Group of saffron extract received 25 mg/kg daily aqueous saffron extract peritoneally for 4 weeks. Lipid profile was measured by enzymatic method with zist shimi commercial kits provided by yasa teb Company. For statistical analysis of data, Kalmogorov- Smirnov test and paired sample and independent sample t- tests (p≤0.05) were used. Results: Findings showed that 4 weeks saffron extract induces significant reduction in LDL, VLDL, TG and Cho of diabetic rats (p=0.001); nevertheless, it has no significant effect on HDL (p=0.07). Conclusion: It is concluded that 4 weeks aqueous saffron extract has lipid lowering effect in diabetic rats

The molecular biology and therapeutic potential of Nrf2 in leukemia

NF-E2-related factor 2 (Nrf2) transcription factor has contradictory roles in cancer, which can act as a tumor suppressor or a proto-oncogene in different cell conditions (depending on the cell type and the conditions of the cell environment). Nrf2 pathway regulates several cellular processes, including signaling, energy metabolism, autophagy, inflammation, redox homeostasis, and antioxidant regulation. As a result, it plays a crucial role in cell survival. Conversely, Nrf2 protects cancerous cells from apoptosis and increases proliferation, angiogenesis, and metastasis. It promotes resistance to chemotherapy and radiotherapy in various solid tumors and hematological malignancies, so we want to elucidate the role of Nrf2 in cancer and the positive point of its targeting. Also, in the past few years, many studies have shown that Nrf2 protects cancer cells, especially leukemic cells, from the effects of chemotherapeutic drugs. The present paper summarizes these studies to scrutinize whether targeting Nrf2 combined with chemotherapy would be a therapeutic approach for leukemia treatment. Also, we discussed how Nrf2 and NF-κB work together to control the cellular redox pathway. The role of these two factors in inflammation (antagonistic) and leukemia (synergistic) is also summarized

Influence of chemical activation of a 35% hydrogen peroxide bleaching gel on its penetration and efficacy--in vitro study

OBJECTIVES: The aim of this study was to evaluate the effects of chemical activation of hydrogen peroxide (HP) gel on colour changes and penetration through the tooth structure. METHODS: One hundred and four bovine incisors were used. One dentine (CD) disc and one enamel-dentine (ED) disc were prepared from each tooth. They were positioned over artificial pulpal chambers and the bleaching was performed with an experimental 35% HP gel. Two control and six experimental groups were prepared. In the positive control group (PC) no chemical activator was used. In the negative control group (NC) the specimens did not receive any bleaching. Each experimental group received a different chemical activator (manganese gluconate-MG; manganese chlorite-MC; ferrous sulphate-FS; ferrous chlorite-FC; and mulberries root extract-MRE). After the bleaching procedure a sample of solution was collected from the artificial pulpal chamber and the HP concentration was measured. The data were analysed using ANOVA, Tukey's, and Dunnett's tests. RESULTS: The groups MG and FS showed a significantly lower penetration of HP than the PC group. For the parameter Delta E, all the groups, with the exception of the group MRE, showed a significantly higher means in relation to the PC group in ED colour. For dentine colour, just the groups MG and FS had significant differences in relation to PC. CONCLUSIONS: The addition of MG and FS decreases the penetration of HP. The chemical activation using metal salts tested was effective in increasing the bleaching effect

The Relationship Between Markers of Oxidative Stress and Depressive Symptoms in Coronary Artery Disease Patients

Depression is highly prevalent and associated with worse prognoses in patients with coronary artery disease (CAD), but underlying mechanisms remain unclear. Oxidative stress, and ensuing lipid peroxidation, may be implicated in both depressive and cardiovascular pathologies but has yet to be assessed in CAD. This study investigated the relationship between depressive symptoms and the lipid peroxidation markers 8-isoprostane (8-ISO), 4-hydroxy-2-nonenal (4-HNE), and lipid hydroperoxides (LPH) in 204 CAD patients. Serum lipid peroxidation markers were analyzed using spectrophotometric assays. Higher concentrations of 8-ISO, a late-stage marker of oxidative damage to lipids, predicted greater depressive symptom severity measured by the Center for Epidemiological Studies Depression Scale (β=0.265, pM.Sc

Best Practices for Successful and Sustainable Journals 2018

The presentation was given at the Third Annual Student Journal Forum organized by the University of Toronto Libraries in January 2018.The University of Toronto Medical Journal (UTMJ) is Canada's oldest student run medical journal, established in 1923. It published articles from universities, institutes, organizations, and medical professionals from around the world. In this presentation UTMJ editors talk about the journal's operations and share best practices for a sustainable and successful production. This is an updated version of the presentation given at the Student Journal Forum 2017

Aesthetic Significance and Failure in Shadi Ghadirian’s Photographic Reflections on War in Nil, Nil

The Iran-Iraq war began in September 1980, immediately following the Iranian Revolution of 1979, and lasted through August 1988. During the war, and for some years after the end of it, the dominant approaches to visualize the war mainly included documentary photography and propagandistic posters and public murals. Later, a gradual aesthetic turn in the realm of the arts replaced the earlier practices. Shadi Ghadirian’s Nil, Nil (2008), a series of eighteen photographs, is one example of this aesthetic turn. Thinking about this turn in postwar Iranian society in general and Iranian art in particular, I examine Nil, Nil both to recount the artistic significance of the work, and to criticize its aesthetic structure, followed by recounting its potential social consequences. As for the artistic significance, I suggest that the artistic reflection on war invalidates the post-revolutionary state’s propagandistic discourse that had exploited the war as a means to promote and sustain its ideological cause. Against the backdrop of the growing internal political tensions, and social frustrations with the consequences of the revolution, I argue that the propagandistic and undemocratic visualization of war was influential on the problematic reception of these visual representations among those parts of the society who were unable to relate to propaganda, which ran short of a more inclusive and all-embracing addressing of war. In this sense, the importance of an artistic contemplation of war lies in its attempt to challenge the propagandistic, exclusive addressing of war, and to come up with possibilities that could unravel the experience of war in more inclusive and all-encompassing ways. As for the aesthetic critique, I argue, according to Theodor W. Adorno’s aesthetic theory, that the formal choice around which Nil, Nil is structured has failed to effectively promote the content. Focusing on the notions of tension, contradiction, and shudder as features of an aesthetic experience, I suggest how the work fails to meet these features, thus lowers itself to the boundaries of kitsch. Finally, I conclude that Nil, Nil’s aesthetic failure, accompanied by the artist’s choice of representing a very individual narration of war, weakens the political effectiveness of the work as it fails to aesthetically diversify the addressing of war

Process Capability Analysis for Simple Linear Profiles in Multistage Processes

When a process is statistically under control, one may be interested in assessing the process performance based on the specification limits provided by the customer. This evaluation is referred to as process capability analysis. Manufacturing operations are often involved with multistage processes, in which the output of a stage is the input of its subsequent stage. This property is known as the cascade property. Existing methods in capability analysis studies are not applicable when a process or product is represented by profiles. This study presents a method to conduct process capability analysis in a multistage process when quality of a product or process is characterized by a simple linear profile. The performance of the proposed method for a two-stage process is evaluated by numerical simulation using an example from the literature. The results indicate that the proposed method eliminates the effect of the cascade property for different shift sizes and autocorrelations