201 research outputs found

    A Study on the Effects of Internal Heat Generation on the Thermal Performance of Solid and Porous Fins using Differential Transformation Method

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    In this study, the impacts of internal heat generation on heat transfer enhancement of porous fin is theoretical investigated using differential transform method. The parametric studies reveal that porosity enhances the finheat dissipating capacity but the internal heat generation decreases the heatenhancement capacity of extended surface. Also, it is established that whenthe internal heat parameter increases to some certain values, some negativeeffects are recorded where the fin stores heat rather than dissipating it. Thisscenario defeats the prime purpose of the cooling fin. Additionally, it is established in the present study that the limiting value of porosity parameterfor thermal stability for the passive device increases as internal heat parameter increases. This shows that although the internal heat parameter canhelp assist higher range and value of thermal stability of the fin, it producesnegative effect which greatly defeats the ultimate purpose of the fin. Theresults in the work will help in fin design for industrial applications whereinternal heat generation is involved

    ANNONA MURICATA LINN. ETHANOLIC LEAF EXTRACT AMELIORATES REPRODUCTIVE COMPLICATIONS IN STREPTOZOTOCIN-INDUCED DIABETIC WISTAR RATS

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    Diabetes mellitus is an endocrine and metabolic disorder of humans and animals characterized by hyperglycemia and low blood insulin levels or insensitivity of target organs to insulin and it’s a major health problem affecting patient’s quality of life due to its many complications. Infertility is one of the major secondary complications in diabetes. Although numerous drugs have been used for intervention studies on diabetes-induced infertility worldwide, there are currently no treatments for diabetes associated infertility in humans. This study was performed to investigate the effects of Annona muricata ethanolic leaf extract (AMELE) on fertility of male diabetic rats and levels of blood glucose. Twenty male Wistar rats (150-200g) were randomly distributed into 4 groups (n=5) treated thus: CTRL (control), DNT, DT1 and DT2 (diabetic, single intraperitoneal injection, streptozotocin, 60 mg/kg). Group DT1 and DT2 received AMELE orally at 100 mg/kg and 200 mg/kg respectively daily for fourteen days. Data were analysed using ANOVA at α0.05. The animals were sacrificed after 2 weeks via thiopental injection and testicular weights were recorded. Fasting blood glucose was determined using a digital glucometer. Sperm count, motility, viability and morphology were assessed microscopically. Testes were histologically evaluated. The results showed that oral administration of AMELE at 100 mg/kg and 200 mg/kg to diabetic male rats for fourteen days significantly decreased blood glucose level and also ameliorated diabetes-induced decreases in sperm functions in streptozotocin-induced diabetic male rats.   &nbsp

    Design and implementation of a prototype active infrared sensor controlled automatic sliding door for mitigation of coronavirus disease 2019 (COVID-19)

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    The door is an essential part of any structure that provides access and security of lives and properties. The manual operation of a door could be cumbersome and laborious when the traffic volume is high. Also, it has been observed that doors could serve as a medium of spreading the deadly coronavirus disease 2019 (COVID-19) infection. Therefore, a prototype automatic sliding door that plays a crucial role in curbing the spread of this infectious diseases has been designed and implemented in this paper. The design of the prototype sliding door is in two parts namely; the structural part and the automation part. The structural design of the door was achieved using the Microsoft Visio 2016 while the design of the automation system was achieved using express printed circuit board. The implementation of the structural part was achieved using 1 inch particle board while the implementation of the automation system was based on the components like the active infrared sensor, resistors (10 kΩ), capacitor (1000 µF), transistors (TIP41 Q8, BC548 Q7), LED indicators, press button switch, pulley system, drive belt, stepper motor (IP65), and ATMEGA 8 microcontroller. The result of the tests carried out on the door showed that the prototype automatic sliding door was characterized by average opening time, closing time, delay time, and optimal sensing range of 3.10 s, 3.05 s, 5.72 s, and 23.5 cm, respectively. It can therefore be concluded from this work that the prototype automatic sliding door is effective in overriding the manual operation of the door

    PLASMA LIPID PROFILE AND SOME BIOCHEMICAL INDICES IN DOMESTICATED GREATER CANE RAT (Thryonomys swinderianus temminck)

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    Some serum biochemical parameters and lipid profile indices were determined in eight male adult greater cane rats Thryonomys swinderianus Temminck, raised under intensive management system. Activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) in plasma were assayed spectrophotometrically, following venopuncture-blood collection and subsequent separation of plasma. Glucose, total protein, albumin and bilirubin as well as lipid profile indices such as total cholesterol, HDL-cholesterol, LDL-cholesterol, VLDL-cholesterol, triglycerides and phospholipids concentration were also determined. In comparison with data from previous studies on wild and captive cane rats, our results indicate lower lipid profile indices and total protein. Activities of hepatic enzymes (AST and ALT) were also lower, while plasma glucose concentration was higher in this third generation greater cane rats. It is concluded that certain aspects of management system in domestication may have a profound influence on biochemical parameters most especially the lower LDL-cholesterol that reduces the risk of atherosclerosis (cardiac disease). This study, therefore offers baseline data for third generation intensively raised greater cane rats.Ă‚

    EFFECTS OF FEED RESTRICTION AND REALIMENTATION ON PERFORMANCE AND NITROGEN UTILISATION IN GROWING WEST AFRICAN DWARF RAMS

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    The effects of feed restriction on the performance of growing West African Dwarf sheep were determined in twenty four (24) growing West African dwarf (WAD) rams with average weight of 8.9 ± 0.59kg. The twenty-four WAD rams were allotted to three treatments of eight rams per treatment and balanced for weight in a Completely Randomized Design. Animals in group C which represents the control were fed with dried Panicum maximum ad libitum and concentrate supplement while group two (R1) and group three (R2) were fed with P. maximum without concentrate supplementation for one and two months, respectively. Thereafter, two months of realimentation followed the restriction. Data were taken on the feed intake, weight gain and digestibility. Results obtained on average daily gain showed significant difference (P < 0.05) whereby sheep on R2 group recorded the lowest value (50.7g/day) during restriction. Digestible organic matter intake (g/Kg 0.75 d-1) for sheep on the C group was significantly (P < 0.05) higher than R1 group, but not significantly (P > 0.05) different from R2 group. The Crude protein intake was highest in the control (49.9g/day). Rumen amino acid of the control animals (4.1) was significantly (P < 0.05) higher than R1 (2.1) and R2 (3.5) groups. Nitrogen intake (g/day) was significant and higher in the C group (8.0) compared to the two restricted groups R1 and R2. During realimentation period, average daily weight gain (g/day) was highest (P < 0.05) for animals in the control (57.5) and least in R2 (34.5). The feed conversion ratio ranged from 8.3 (C) to 14.3 (R2) while the total weight gain (kg) ranged from 2.1 (R2) to 3.5 (C). Similarly, the CP intake (g/day) was higher in the control group compared to those in R1 and R2 groups. However, the dietary amino acid recorded in R2 differ significantly (P < 0.05) from R1 and C groups. During the realimentation period, nitrogen intake for rams in R1 (8.8g/day) and R2 (10.1g/day) groups doubled the values obtained during the restriction period. It was concluded that rams should be restricted for one month because they gained more weight than those restricted for two months.Â

    A suspected case of digitalis toxicity secondary to therapeutic management of congestive heart failure in a Boerboel dog

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    A 15 months old male Boerboel, weighing 25kg presented to Veterinary Teaching Hospital, Abeokuta, Nigeria, with complaint of abdominal distention, emaciation and anorexia was diagnosed of congestive heart failure (CHF) of unknown etiology. At presentation, prominent S- wave voltages in lead II, III electrocardiogram, a positive R-wave in lead AVR and a mean electrical axis of -900 suggestive of right ventricular enlargement were evident. A right atrial enlargement was also suspected due to the presence of a tented P-wave on the electrocardiogram. Digoxin was administered at 0.01 mg/kg orally, once daily to increase cardiac contractility and reduce heart rate; Enalapril given at 0.5 mg/kg orally once daily was to blunt the renin angiotensin aldosterone response, Furosemide at 2mg/kg orally, once daily was administered to increase natriuresis and diuresis. After 2 weeks of medication the dogs exhibited signs of digitalis toxicity such as ventricular premature contraction, ventricular tachycardia. This case is a rare occurrence and has not been reported in our veterinary clinics. The management of CHF with standard dose regime of digitalis requires therapeutic drug monitoring as it could result in breed specific toxicity

    Antibacterial Activity of Vanillic Acid against Staphylococcus aureus, Salmonella typhi, and Proteus mirabilis

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    Aim. This study investigated the efficacy of vanillic acid against selected pathogenic bacteria obtained from clinical samples. Method. The antibacterial efficacy of vanillic acid against selected pathogenic bacteria collected from clinical samples was studied using a broth macrodilution method. The minimum inhibitory concentration was determined by treating each isolate with increasing amounts of vanillic acid ranging from 150 to 2000 µg/ml. Results. The lowest inhibitory concentrations found were 600 µg/ml for Staphylococcus aureus, Proteus mirabilis, and Salmonella Typhi, and the time-kill susceptibility test also demonstrated a significant reduction in viable cells of the bacterial isolates investigated in this study. The findings of this study confirmed the antimicrobial effect of vanillic acid on bacterial growth and its activity against Staphylococcus aureus, Proteus mirabilis, and Salmonella Typhi. Conclusion. Vanillic acid may provide a solution for alternate therapeutic choices for diseases caused by Staphylococcus aureus, Proteus mirabilis, and Salmonella Typhi

    Development of an improved dug canoe for artisanal fisheries

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    A dug canoe similar to the one commonly used by artisanal fisherfolks 4.82M (LOA) was designed and constructed using locally available materials, as an alternative to hardwood that is becoming very scarce. The canoe have least cost, easy construction, adequate stability, light weight and easy maneuverability, as its attributes. The light displacement (weight empty) was 37kg which is light enough in relation to craft of same size commonly used by fishermen. The capacity of the canoe was 210 kg (3 persons) and total production cost of N18,400 which is not beyond the reach of an average fisherfolk. The craft is small and fall among the category of crafts that account for the greater percentage of national fish landing. The canoe also closely resembles the local fishing crafts, hence easy acceptance by local fisherfolk

    Quality of sleep and psychological morbidity among paramedical and medical students in Southwest Nigeria

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    Objective: The objective of this study was to compare the quality of sleep and psychological morbidity between medical students and paramedical students.Methods: A cross sectional survey of one hundred and eighty-six students of the College of Medicine, Olabisi Onabanjo University, Ogun State, Nigeria, were surveyed using socio-demographic questionnaires, Pittsburgh Sleep Questionnaire and General Health questionnaire.Results: The mean ages among paramedical students was 20.63±1.6 and medical students was 22.80±2.93 respectively. Medical Students had a higher percentage of those who had poor sleep quality (86.7% ,≥ 5, n=85) than the paramedical students (38.6%, n=34) and higher mean scores on General Health Questionnaire, M(SD) = 8.75(5.01) than the Paramedical group, M(SD) = 6.53(2.97) respectively.Conclusion: The findings in our study showed that medical students had poorer sleep quality and higher psychological morbidity in comparison to paramedical students, efforts should be made to reduce academic stress and improving sleep quality.Keywords: Sleep, Psychological Morbidity, Medical Students, Paramedical Students, Medical Educatio
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