46 research outputs found

    Issues of cultural diversity, migration, and displacement in teacher education programmes

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    eaching in a context of cultural diversity requires specific competencies to impart common fundamental values, communicate effectively with families and students, take an active stand against all forms of discrimination, and conduct psychosocial interventions. In particular this article aims to identify the main topics that are covered and methods used in the training courses (practical vs theoretical approach). The current work focuses on teacher training programmes in five main categories capturing different aspects of cultural diversity, migration and displacement. Among them are: cross-cultural knowledge, sensitivity and awareness of different cultures, intercultural and professional communication skills, culturally responsive pedagogic approaches and psychosocial interventions. Key examples of teacher training programmes in these categories are discussed and recommendations are proposed in orderto improve the quality of teacher education and ultimately improve the inclusion and academic success of displaced students and those from a migrant background.The following sections examine the role of teachers, particularly in culturally diverse settings. Next, the analysis focuses on each of the five main categories of teacher training for cultural diversity. The paper examines if there is a difference in teachers’ training courses on offer in low and high-immigration countries respectively. In order to provide better understanding of the content of the courses the paper then presents a few case studies of programmes offered across different countries

    Analysis of predictive factors influencing dupilumab continuation rate in adult patients with atopic dermatitis. results from an italian multicenter study

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    Objectives: The purpose of this study was to analyze the drug survival rate of dupilumab up to 2 years in a large real-world cohort of adult patients affected by moderate/severe atopic dermatitis (AD), and to investigate the clinical, demographic and predictive factors influencing the patients’ treatment persistence. Material and methods: This study included adult patients affected by moderate-to-severe AD treated with dupilumab for at least 16 weeks who visited 7 dermatologic outpatient clinics in Lazio, Italy, from January 2019 until August 2021. Results: A total of 659 adult patients (345 male [52.3%], mean age: 42.8 years) with an average treatment duration of 23.3 months were enrolled in the study. Overall, 88.6% and 76.1% of patients were still on treatment after 12 and 24 months, respectively. The drug survival rate for discontinuation due to AEs and dupilumab ineffectiveness was 95.0% at 12 months and 90.0% at 24 months. The main reasons for drug discontinuation included inefficacy (29.6%), failed compliance (17.4%), persistent efficacy (20.4%) and adverse events (7.8%). Adult AD onset (≥18 years) and EASI score severity measured at the last follow-up visit were the only factors significantly associated with lower drug survival. Conclusion: This study revealed an increased cumulative probability of dupilumab survival at 2 years, reflected by a sustained effectiveness and a favorable safety profile of the drug

    Ins and outs of the Dutch life course savings scheme

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    Item does not contain fulltextStudiedag 'PAS: hoe verder na het arrest van het Hof van Justitie?' van het Instituut voor Bouwrecht, 11 december 2018Utrecht : [S.n.

    Enzymic enhancement of W3 polyunsaturated fatty acids content in brazilian sardine oil

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    Se ensayaron cuatro lipasas microbianas con la intención de aumentar el contenido de los ácidos grasos poliinsaturados de la serie W3 (AGPI W3) en la fracción de glicéridos no hidrolizados después de la hidrólisis del aceite de sardina brasileño. La lipasa de Candida cylindracea fue la más eficiente entre las enzimas ensayadas, aumentando el contenido de ácido decosahexaenoico (DHA) del 10,2% en el aceite original al 22,5% en relación a los ácidos grasos totales después de 16 h de reacción a 35 °C, lo que equivale a un incremento del 120% en relación a la cantidad presente antes de la hidrólisis. Las cuatro lipasas probadas no fueron eficientes para aumentar el contenido del ácido eicosapentenoico (EPA) en el aceite de sardina brasileño en las condiciones del ensayo.In an attempt to concentrate the content of W3 polyunsaturated fatty acids ( W3 PUFA) in the partially hydrolyzed glycerides, Brazilian sardine oil was hydrolyzed with four kinds of microbial lipases. The enzyme from Candida cylindracea was the most effective for the production of oil with high concentration of docosahexaenoic acid (DHA). Sardine oil was treated at 35 °C with this lipase for 16 h reaction and 60.0% hydrolysis resulted in an increase in the DHA content from 10.2% in the original oil to 22.5% (2.20- fold enrichment) in the unhydrolysed acylglycerol. None the four lipases tested could raise the EPA content significantly.Colegio de Farmacéuticos de la Provincia de Buenos Aire

    Enzymic enhancement of W3 polyunsaturated fatty acids content in brazilian sardine oil

    No full text
    Se ensayaron cuatro lipasas microbianas con la intención de aumentar el contenido de los ácidos grasos poliinsaturados de la serie W3 (AGPI W3) en la fracción de glicéridos no hidrolizados después de la hidrólisis del aceite de sardina brasileño. La lipasa de Candida cylindracea fue la más eficiente entre las enzimas ensayadas, aumentando el contenido de ácido decosahexaenoico (DHA) del 10,2% en el aceite original al 22,5% en relación a los ácidos grasos totales después de 16 h de reacción a 35 °C, lo que equivale a un incremento del 120% en relación a la cantidad presente antes de la hidrólisis. Las cuatro lipasas probadas no fueron eficientes para aumentar el contenido del ácido eicosapentenoico (EPA) en el aceite de sardina brasileño en las condiciones del ensayo.In an attempt to concentrate the content of W3 polyunsaturated fatty acids ( W3 PUFA) in the partially hydrolyzed glycerides, Brazilian sardine oil was hydrolyzed with four kinds of microbial lipases. The enzyme from Candida cylindracea was the most effective for the production of oil with high concentration of docosahexaenoic acid (DHA). Sardine oil was treated at 35 °C with this lipase for 16 h reaction and 60.0% hydrolysis resulted in an increase in the DHA content from 10.2% in the original oil to 22.5% (2.20- fold enrichment) in the unhydrolysed acylglycerol. None the four lipases tested could raise the EPA content significantly.Colegio de Farmacéuticos de la Provincia de Buenos Aire

    A Quality Control System for Automated Prostate Segmentation on T2-Weighted MRI

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    Computer-aided detection and diagnosis (CAD) systems have the potential to improve robustness and efficiency compared to traditional radiological reading of magnetic resonance imaging (MRI). Fully automated segmentation of the prostate is a crucial step of CAD for prostate cancer, but visual inspection is still required to detect poorly segmented cases. The aim of this work was therefore to establish a fully automated quality control (QC) system for prostate segmentation based on T2-weighted MRI. Four different deep learning-based segmentation methods were used to segment the prostate for 585 patients. First order, shape and textural radiomics features were extracted from the segmented prostate masks. A reference quality score (QS) was calculated for each automated segmentation in comparison to a manual segmentation. A least absolute shrinkage and selection operator (LASSO) was trained and optimized on a randomly assigned training dataset (N = 1756, 439 cases from each segmentation method) to build a generalizable linear regression model based on the radiomics features that best estimated the reference QS. Subsequently, the model was used to estimate the QSs for an independent testing dataset (N = 584, 146 cases from each segmentation method). The mean ± standard deviation absolute error between the estimated and reference QSs was 5.47 ± 6.33 on a scale from 0 to 100. In addition, we found a strong correlation between the estimated and reference QSs (rho = 0.70). In conclusion, we developed an automated QC system that may be helpful for evaluating the quality of automated prostate segmentations
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