148 research outputs found

    How Does International Competitiveness Affect Economic Development? A Two-Phase Hypothesis

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    This paper analyses the impact of international competitiveness on economic development, based on the World Economic Forum Global Competitiveness Index (GCI) and GDP/capita of 125 countries during the period 2007-2010. The results reveal two phases of the evolution of competitiveness. When GCI < 4.5 (on 1-7 scale), any improvement of a country’s competitiveness affects current development more than future development. When a country’s GCI rises above 4.5, further improvements of competitiveness will affect future development more than current development. The 4.5 competitiveness threshold is remarkably stable throughout analyzed period.Hanna Adamkiewicz: [email protected]; Stanislaw Kot: [email protected] Adamkiewicz - Faculty of Management and Economics, Gdansk University of Technology; Stanislaw Kot - Faculty of Management and Economics, Gdansk University of Technology5(71)303

    Impact of Globalisation on Competitiveness of Countries

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    Celem pracy jest rozstrzygnięcie problemu, w jaki sposób procesy globalizacji oddziałują na konkurencyjność krajów (konkurencyjność międzynarodową). Odpowiedzi na to pytanie udzielają cztery hipotezy. Pierwsza (H1) brzmi następująco: Globalizacja oddziałuje pozytywnie na konkurencyjność krajów z opóźnieniem trzech lat. Dla poszczególnych wymiarów konkurencyjności międzynarodowej sformułowano niniejsze hipotezy: H2: Globalizacja oddziałuje pozytywnie na warunki podstawowe (ang. Basic Requirements) z opóźnieniem trzech lat; H3: Globalizacja oddziałuje pozytywnie na czynniki zwiększające efektywność (ang. Efficiency Enhancers) z opóźnieniem jednego roku, ale negatywnie z opóźnieniem trzech lat; H4: Globalizacja oddziałuje negatywnie na innowacje (ang. Innovations) z opóźnieniem trzech lat. Sformułowane hipotezy weryfikowano na podstawie danych panelowych dla 137 krajów za okres 2006-2011. Oszacowano cztery modele panelowe typu fixed-effects ze zmiennymi zależnymi w postaci indeksów konkurencyjności Światowego Forum Ekonomicznego oraz ze zmiennymi niezależnymi w postaci ogólnego indeksu globalizacji KOF (Szwajcarski Instytut Ekonomiczny, niem. Konjunkturforschungsstelle) i jego wartościami opóźnionymi w czasie. jako podwymiary przyjęto indeksy KOF.The aim of this paper is to address the question of how globalisation processes affect the competitiveness of nations (international competitiveness). Four hypotheses are formed to provide answers to this question. H1: Globalisation positively affects international competitiveness with a three-year lag. For particular dimensions of international competitiveness, the following hypotheses are made: H2: Globalisation positively affects basic requirements with a three-year lag; H3: Globalisation positively affects efficiency enhancers with a one-year lag, but negatively with a threeyear lag; H4: Globalisation negatively affects innovation and sophistication factors with a three-year lag. Panel data from 137 countries for the years 2006-2011 are used for statistical verification of the said hypotheses. Fixed effects models are estimated, with World Economic Forum’s indices of competitiveness as dependent variables, and KOF overall globalisation index and its lagged values as independent variables.Hanna G. Adamkiewicz-Drwiłło: [email protected] hab. Hanna G. Adamkiewicz-Drwiłło – Wydział Zarządzania i Ekonomii, Politechnika Gdańska4(70)11112

    Exhaled Nitric Oxide in Children with Asthma and Short-Term PM(2.5) Exposure in Seattle

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    The objective of this study was to evaluate associations between short-term (hourly) exposures to particulate matter with aerodynamic diameters < 2.5 μm (PM(2.5)) and the fractional concentration of nitric oxide in exhaled breath (Fe(NO)) in children with asthma participating in an intensive panel study in Seattle, Washington. The exposure data were collected with tapered element oscillation microbalance (TEOM) PM(2.5) monitors operated by the local air agency at three sites in the Seattle area. Fe(NO) is a marker of airway inflammation and is elevated in individuals with asthma. Previously, we reported that offline measurements of Fe(NO) are associated with 24-hr average PM(2.5) in a panel of 19 children with asthma in Seattle. In the present study using the same children, we used a polynomial distributed lag model to assess the association between hourly lags in PM(2.5) exposure and Fe(NO) levels. Our model controlled for age, ambient NO levels, temperature, relative humidity, and modification by use of inhaled corticosteroids. We found that Fe(NO) was associated with hourly averages of PM(2.5) up to 10–12 hr after exposure. The sum of the coefficients for the lag times associated with PM(2.5) in the distributed lag model was 7.0 ppm Fe(NO). The single-lag-model Fe(NO) effect was 6.9 [95% confidence interval (CI), 3.4 to 10.6 ppb] for a 1-hr lag, 6.3 (95% CI, 2.6 to 9.9 ppb ) for a 4-hr lag, and 0.5 (95% CI, −1.1 to 2.1 ppb) for an 8-hr lag. These data provide new information concerning the lag structure between PM(2.5) exposure and a respiratory health outcome in children with asthma

    Reporting to parents on children’s exposures to asthma triggers in low-income and public housing, an interview-based case study of ethics, environmental literacy, individual action, and public health benefits

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    Background Emerging evidence about the effects of endocrine disruptors on asthma symptoms suggests new opportunities to reduce asthma by changing personal environments. Right-to-know ethics supports returning personal results for these chemicals to participants, so they can make decisions to reduce exposures. Yet researchers and institutional review boards have been reluctant to approve results reports in low-income communities, which are disproportionately affected by asthma. Concerns include limited literacy, lack of resources to reduce exposures, co-occurring stressors, and lack of models for effective reporting. To better understand the ethical and public health implications of returning personal results in low-income communities, we investigated parents’ experiences of learning their children’s environmental chemical and biomonitoring results in the Green Housing Study of asthma. Methods The Green Housing Study measured indoor chemical exposures, allergens, and children’s asthma symptoms in “green”-renovated public housing and control sites in metro-Boston and Cincinnati in 2011–2013. We developed reports for parents of children in the study, including results for their child and community. We observed community meetings where results were reported, and metro-Boston residents participated in semi-structured interviews in 2015 about their report-back experience. Interviews were systematically coded and analyzed. Results Report-back was positively received, contributed to greater understanding, built trust between researchers and participants, and facilitated action to improve health. Sampling visits and community meetings also contributed to creating a positive study experience for participants. Participants were able to make changes in their homes, such as altering product use and habits that may reduce asthma symptoms, though some faced roadblocks from family members. Participants also gained access to medical resources, though some felt that clinicians were not responsive. Participants wanted larger scale change from government or industry and wanted researchers to leverage study results to achieve change. Conclusions Report-back on environmental chemical exposures in low-income communities can enhance research benefits by engaging residents with personally relevant information that informs and motivates actions to reduce exposure to asthma triggers. Ethical practices in research should support deliberative report-back in vulnerable communities

    Urban public health, a multidisciplinary approach

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    Urban environment is a highly complex interactive socio-physical system, with competing expectations and priorities. Public health interventions have always had a fundamental role in the control of diseases in cities. WHO considers urbanization as one of the key challenges for public health in the twenty-first century, since cities offer significant opportunities to improve public health if health-enhancing policies and actions are promoted. A multidisciplinary approach is required, but the basic differences existing between technical and health disciplines make the interaction difficult. The multidisciplinary collaboration is still at a very early stage of development, and needs to be further understood and planned. The author concludes stressing the need for a transversal training, but also for sharing knowledge, instruments and methods, involving all the actors in the planning process, to develop a real multidisciplinary approach

    Is FLT3 internal tandem duplication an unfavorable risk factor for high risk children with acute myeloid leukemia? : Polish experience

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    According to the AML-BFM 2004 Interim, a treatment protocol used in Poland since 2005, presence of FLT3 internal tandem duplication (FLT3/ITD) qualifies a patient with acute myeloid leukemia (AML) to a high-risk group (HRG). The present study was aimed to identify the prevalence of FLT3/ITD in children with AML in Poland and to evaluate its prognostic significance in the HRG patients. Out of 291 children with de novo AML treated in 14 Polish centers between January 2006 and December 2012, samples from 174 patients were available for FLT3/ITD analysis. Among study patients 108 children (61.7%) were qualified to HRG. Genomic DNA samples from bone marrow were tested for identification of FLT3/ITD mutation by PCR amplification of exon 14 and 15 of FLT3 gene. Clinical features and treatment outcome in patients with and without FLT3/ITD were analyzed in the study. The FLT3/ITD was found in 14 (12.9%) of 108 HRG children. There were no significant differences between children with and without FLT3/ITD in age and FAB distribution. The white blood cells count in peripheral blood at diagnosis was significantly higher (p <0.01) in the children with FLT3/ITD. Over 5-year overall survival rate for FLT3/ITD positive children was worse (42.4%) comparing to FLT3/ITD negative children (58.9%), but the statistical difference was not significant. However, over 5-year survivals free from treatment failures were similar. The FLT3/ITD rate (12.9%) observed in the study corresponded to the published data. There was no significant impact of FLT3/ITD mutation on survival rates, although further studies are needed on this subject

    Glomerular filtration rate and prevalence of chronic kidney disease in Wilms’ tumour survivors

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    Glomerular filtration rate (GFR) was evaluated in 32 Wilms’ tumour survivors (WTs) in a cross-sectional study using 99 Tc-diethylene triamine pentaacetic acid (99 Tc-DTPA) clearance, the Schwartz formula, the new Schwartz equation for chronic kidney disease (CKD), cystatin C serum concentration and the Filler formula. Kidney damage was established by beta-2-microglobulin (B-2-M) and albumin urine excretion, urine sediment and ultrasound examination. Blood pressure was measured. No differences were found between the mean GFR in 99 Tc-DTPA and the new Schwartz equation for CKD (91.8 ± 11.3 vs. 94.3 ± 10.2 ml/min/1.73 m2 [p = 0.55] respectively). No differences were observed between estimated glomerular filtration rate (eGFR) using the Schwartz formula and the Filler formula either (122.3 ± 19.9 vs. 129.8 ± 23.9 ml/min/1.73 m2 [p = 0.28] respectively). Increased urine albumin and B-2-M excretion, which are signs of kidney damage, were found in 7 (22%) and 3 (9.4%) WTs respectively. Ultrasound signs of kidney damage were found in 14 patients (43%). Five patients (15.6%) had more than one sign of kidney damage. Eighteen individuals (56.25%) had CKD stage I (10 with signs of kidney damage; 8 without). Fourteen individuals (43.75%) had CKD stage II (6 with signs of kidney damage; 8 without). The new Schwartz equation for CKD better estimated GFR in comparison to the Schwartz formula and the Filler formula. Furthermore, the WT survivors had signs of kidney damage despite the fact that GFR was not decreased below 90 ml/min/1.73 m2 with 99 Tc- DTPA
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