On Instruments for Engagement

A commissioned essay for the catalogue that accompanied the Archizines exhibition first held at the Architectural Association, London. Informed by a variety of primary and secondary research sources, this essay intended to highlight and critically analyse the work of a range of practitioners who have deliberately removed themselves from mainstream media outlets and are concerned with using photography as a visual language to critique and focus attention on the spaces that we occupy and contribute to the wider debate regarding architecture and the built environment

The Poetic Archive: Photography, Everyday Life and the Tactic of Self-Publishing

Preston is my Paris was co-founded by Adam Murray and Robert Parkinson in June 2009. The project originally began as a photocopied zine specifically focussing on the city of Preston but has since developed into a multi-faceted photographic archive consisting of 40 self-published works that address themes relating to everyday life and social consciousness. In contrast to other photographic investigations of everyday life which often result in gallery exhibitions or lavishly produced books, Murray and Parkinson intentionally appropriate vernacular methods of production and print materials such as photocopying and newsprint with the aim to produce an archive that deliberately intends to engage with an audience beyond the conventional art world. This paper discusses this body of work and the role that the tactic of self-publishing has in a contemporary photographic context

Escape from anger and other Buddhist contributions to the philosophy of emotions, An

2016 Summer.Includes bibliographical references.This paper begins with an examination of several theories of emotion in general—a ‘mixed theory’, an ‘attitudinal theory’, and a Buddhist ‘componential theory.’ I argue that the Buddhist theory has a theoretical advantage over these alternatives insofar as it avoids two ‘thin’ characterizations of emotions that exclude either affective or conative states from the concept. The Buddhist theory of emotions, I claim, has another advantage insofar as it brings practicality to the forefront, connecting our theorizing about emotions with what is most important—developing good character and bringing about the welfare of beings. Chapter 2 proceeds to an in- depth analysis of the emotion of anger in particular, examining several philosophically important accounts—those of Aristotle, Seneca, and the Buddha. I raise problems of definition, highlight some typical and contentious features of anger, and draw from several classical sources to reconstruct a Buddhist account of anger. In the final chapter, I argue that typical anger is not necessary for moral life, addressing myself to arguments from Zac Cogley and Emily McRae. I continue by demonstrating that Buddhism has resources that allow us to both eliminate or largely attenuate anger, and to approach the problems we face without anger; finally, I sketch out exactly how this can be accomplished

Palatability Effects of Blade Tenderization on Beef Top Sirloin Steaks

The objective of this study was to determine if consumer satisfaction improves by blade tenderizing today’s more inherently tender beef. Paired USDA Choice top sirloin butts (n = 20 total pieces) were collected from 10 carcasses representative of the typical carcass in today’s fed beef market. Paired top sirloin butts were subjected to Warner-Bratzler Shear (WBS) force testing as a measure of objective tenderness. Consumer sensory evaluation was used to determine if consumers could discern differences in tenderness, flavor, juiciness, and overall likability between steaks from blade tenderized (BT) subprimals and steaks from non-blade tenderized (NBT) subprimals. Top sirloins from the left side of the carcass were blade tenderized once before portioning into steaks, whereas top sirloins from the right side of the carcass received no treatment and served as the control. Consumers found BT steaks to have higher (P 0.05), nor did WBS force values (P > 0.05). These data indicate that blade tenderization is an important process to improve consumer tenderness, flavor, and overall likability of beef top sirloins

Overexpression of Sox11 Promotes Corticospinal Tract Regeneration after Spinal Injury While Interfering with Functional Recovery

Embryonic neurons, peripheral neurons, and CNS neurons in zebrafish respond to axon injury by initiating pro-regenerative transcriptional programs that enable axons to extend, locate appropriate targets, and ultimately contribute to behavioral recovery. In contrast, many long-distance projection neurons in the adult mammalian CNS, notably corticospinal tract (CST) neurons, display a much lower regenerative capacity. To promote CNS repair, a long-standing goal has been to activate pro-regenerative mechanisms that are normally missing from injured CNS neurons. Sox11 is a transcription factor whose expression is common to a many types of regenerating neurons, but it is unknown whether suboptimal Sox11 expression contributes to low regenerative capacity in the adult mammalian CNS. Here we show in adult mice that dorsal root ganglion neurons (DRGs) and CST neurons fail to upregulate Sox11 after spinal axon injury. Furthermore, forced viral expression of Sox11 reduces axonal dieback of DRG axons, and promotes CST sprouting and regenerative axon growth in both acute and chronic injury paradigms. In tests of forelimb dexterity, however, Sox11 overexpression in the cortex caused a modest but consistent behavioral impairment. These data identify Sox11 as a key transcription factor that can confer an elevated innate regenerative capacity to CNS neurons. The results also demonstrate an unexpected dissociation between axon growth and behavioral outcome, highlighting the need for additional strategies to optimize the functional output of stimulated neurons

Inferring the eccentricity distribution

Standard maximum-likelihood estimators for binary-star and exoplanet eccentricities are biased high, in the sense that the estimated eccentricity tends to be larger than the true eccentricity. As with most non-trivial observables, a simple histogram of estimated eccentricities is not a good estimate of the true eccentricity distribution. Here we develop and test a hierarchical probabilistic method for performing the relevant meta-analysis, that is, inferring the true eccentricity distribution, taking as input the likelihood functions for the individual-star eccentricities, or samplings of the posterior probability distributions for the eccentricities (under a given, uninformative prior). The method is a simple implementation of a hierarchical Bayesian model; it can also be seen as a kind of heteroscedastic deconvolution. It can be applied to any quantity measured with finite precision--other orbital parameters, or indeed any astronomical measurements of any kind, including magnitudes, parallaxes, or photometric redshifts--so long as the measurements have been communicated as a likelihood function or a posterior sampling.Comment: Ap

Tree of Life Synagogue Shooting in Pittsburgh: Preparedness, Prehospital Care, and Lessons Learned

On Saturday, October 27, 2018, a man with anti-Semitic motivations entered Tree of Life synagogue in the Squirrel Hill section of Pittsburgh, Pennsylvania; he had an AR-15 semi-automatic rifle and three handguns, opening fire upon worshippers. Eventually 11 civilians died at the scene and eight people sustained non-fatal injuries, including five police officers. Each person injured but alive at the scene received care at one of three local level-one trauma centers.  The injured had wounds often seen in war-settings, with the signature of high velocity weaponry.  We describe the scene response, specific elements of our hospital plans, the overall out-of-hospital preparedness in Pittsburgh, and the lessons learned