Integration and Conventional Systems at STAR

At the beginning of the design and construction of the STAR Detector, the collaboration assigned a team of physicists and engineers the responsibility of coordinating the construction of the detector. This group managed the general space assignments for each sub-system and coordinated the assembly and planning for the detector. Furthermore, as this group was the only STAR group with the responsibility of looking at the system as a whole, the collaboration assigned it several tasks that spanned the different sub-detectors. These items included grounding, rack layout, cable distribution, electrical, power and water, and safety systems. This paper describes these systems and their performance.Comment: 17 pages, 6 figures, Contribution to a NIM Volume Dedicated to the Detectors and the Accelerator at RHI

Dark Matter and Dark Radiation

We explore the feasibility and astrophysical consequences of a new long-range U(1) gauge field ("dark electromagnetism") that couples only to dark matter, not to the Standard Model. The dark matter consists of an equal number of positive and negative charges under the new force, but annihilations are suppressed if the dark matter mass is sufficiently high and the dark fine-structure constant $\hat\alpha$ is sufficiently small. The correct relic abundance can be obtained if the dark matter also couples to the conventional weak interactions, and we verify that this is consistent with particle-physics constraints. The primary limit on $\hat\alpha$ comes from the demand that the dark matter be effectively collisionless in galactic dynamics, which implies $\hat\alpha \lesssim 10^{-4}$ for TeV-scale dark matter. These values are easily compatible with constraints from structure formation and primordial nucleosynthesis. We raise the prospect of interesting new plasma effects in dark matter dynamics, which remain to be explored.Comment: 14 pages, 6 figures Updated equations and figure

Novel Characteristics of Valveless Pumping

This study investigates the occurrence of valveless pumping in a fluidfilled system consisting of two open tanks connected by an elastic tube. We show that directional flow can be achieved by introducing a periodic pinching applied at an asymmetrical location along the tube, and that the flow direction depends on the pumping frequency. We propose a relation between wave propagation velocity, tube length, and resonance frequencies associated with shifts in the pumping direction using numerical simulations. The eigenfrequencies of the system are estimated from the linearized system, and we show that these eigenfrequencies constitute the resonance frequencies and the horizontal slope frequencies of the system; 'horizontal slope frequency' being a new concept. A simple model is suggested, explaining the effect of the gravity driven part of the oscillation observed in response to the tank and tube diameter changes. Results are partly compared with experimental findings.Art. no. 22450

Remote sensing of ice crystal asymmetry parameter using multi-directional polarization measurements – Part 1: Methodology and evaluation with simulated measurements

We present a new remote sensing technique to infer the average asymmetry parameter of ice crystals near cloud top from multi-directional polarization measurements. The method is based on previous findings that (a) complex aggregates of hexagonal crystals generally have scattering phase matrices resembling those of their components; and (b) scattering phase matrices systematically vary with aspect ratios of crystals and their degree of microscale surface roughness. Ice cloud asymmetry parameters are inferred from multi-directional polarized reflectance measurements by searching for the closest fit in a look-up table of simulated polarized reflectances computed for cloud layers that contain individual, randomly oriented hexagonal columns and plates with varying aspect ratios and roughness values. The asymmetry parameter of the hexagonal particle that leads to the best fit with the measurements is considered the retrieved value. For clouds with optical thickness less than 5, the cloud optical thickness must be retrieved simultaneously with the asymmetry parameter, while for optically thicker clouds the asymmetry parameter retrieval is independent of cloud optical thickness. Evaluation of the technique using simulated measurements based on the optical properties of a number of complex particles and their mixtures shows that the ice crystal asymmetry parameters are generally retrieved to within 5%, or about 0.04 in absolute terms. The retrieval scheme is largely independent of calibration errors, range and sampling density of scattering angles and random noise in the measurements. The approach can be applied to measurements of past, current and future airborne and satellite instruments that measure multi-directional polarized reflectances of ice-topped clouds

Beyond Outerplanarity

We study straight-line drawings of graphs where the vertices are placed in convex position in the plane, i.e., convex drawings. We consider two families of graph classes with nice convex drawings: outer $k$-planar graphs, where each edge is crossed by at most $k$ other edges; and, outer $k$-quasi-planar graphs where no $k$ edges can mutually cross. We show that the outer $k$-planar graphs are $(\lfloor\sqrt{4k+1}\rfloor+1)$-degenerate, and consequently that every outer $k$-planar graph can be $(\lfloor\sqrt{4k+1}\rfloor+2)$-colored, and this bound is tight. We further show that every outer $k$-planar graph has a balanced separator of size $O(k)$. This implies that every outer $k$-planar graph has treewidth $O(k)$. For fixed $k$, these small balanced separators allow us to obtain a simple quasi-polynomial time algorithm to test whether a given graph is outer $k$-planar, i.e., none of these recognition problems are NP-complete unless ETH fails. For the outer $k$-quasi-planar graphs we prove that, unlike other beyond-planar graph classes, every edge-maximal $n$-vertex outer $k$-quasi planar graph has the same number of edges, namely $2(k-1)n - \binom{2k-1}{2}$. We also construct planar 3-trees that are not outer $3$-quasi-planar. Finally, we restrict outer $k$-planar and outer $k$-quasi-planar drawings to \emph{closed} drawings, where the vertex sequence on the boundary is a cycle in the graph. For each $k$, we express closed outer $k$-planarity and \emph{closed outer $k$-quasi-planarity} in extended monadic second-order logic. Thus, closed outer $k$-planarity is linear-time testable by Courcelle's Theorem.Comment: Appears in the Proceedings of the 25th International Symposium on Graph Drawing and Network Visualization (GD 2017

Fatty liver in familial hypobetalipoproteinemia: Triglyceride assembly into VLDL particles is affected by the extent of hepatic steatosis

Familial hypobetalipoproteinemia (FHBL) subjects may develop fatty liver. Liver fat was assessed in 21 FHBL with six different apolipoprotein B (apoB) truncations (apoB-4 to apoB-89) and 14 controls by magnetic resonance spectroscopy (MRS). Liver fat percentages were 16.7 ± 11.5 and 3.3 ± 2.9 (mean ± SD) (P = 0.001). Liver fat percentage was positively correlated with body mass index, waist circumference, and areas under the insulin curves of 2 h glucose tolerance tests, suggesting that obesity may affect the severity of liver fat accumulation in both groups. Despite 5-fold differences in liver fat percentage, mean values for obesity and insulin indexes were similar. Thus, for similar degrees of obesity, FHBL subjects have more hepatic fat. VLDL-triglyceride (TG)-fatty acids arise from plasma and nonplasma sources (liver and splanchnic tissues). To assess the relative contributions of each, [2H2] palmitate was infused over 12 h in 13 FHBL subjects and 11 controls. Isotopic enrichment of plasma free palmitate and VLDL-TG-palmitate was determined by mass spectrometry. Nonplasma sources contributed 51 ± 15% in FHBL and 37 ± 13% in controls (P = 0.02). Correlations of liver fat percentage and percent VLDL-TG-palmitate from liver were r = 0.89 (P = 0.0001) for FHBL subjects and r = 0.69 (P = 0.01) for controls. Thus, apoB truncation-producing mutations result in fatty liver and in altered assembly of VLDL-TG

Ocular Itch Relief with Alcaftadine 0.25% Versus Olopatadine 0.2% in Allergic Conjunctivitis: Pooled Analysis of Two Multicenter Randomized Clinical Trials

Introduction: The efficacy and safety of the once-daily topical ophthalmic solutions, alcaftadine 0.25% and olopatadine 0.2%, in preventing ocular itching associated with allergic conjunctivitis were evaluated. Methods: Pooled analysis was conducted of two double-masked, multicenter, active- and placebo-controlled studies using the conjunctival allergen challenge (CAC) model of allergic conjunctivitis. Subjects were randomized 1:1:1 to receive alcaftadine 0.25%, olopatadine 0.2%, or placebo. The primary efficacy measure was subject-evaluated mean ocular itching at 3 min post-CAC and 16 h after treatment instillation. Secondary measures included ocular itching at 5 and 7 min post-CAC. Ocular itch was determined over all time points measured (3, 5, and 7 min) post-CAC and the proportion of subjects with minimal itch (itch score <1) and zero itch (itch score = 0) was also assessed. Results: A total of 284 subjects were enrolled in the two studies. At 3 min post-CAC and 16 h after treatment instillation, alcaftadine 0.25% achieved a significantly lower mean itch score compared with olopatadine 0.2% (0.50 vs. 0.87, respectively; P = 0.0006). Alcaftadine demonstrated a significantly lower mean itch score over all time points compared with olopatadine (0.68 vs. 0.92, respectively; P = 0.0390); both alcaftadine- and olopatadine-treated subjects achieved significantly lower overall mean ocular itching scores compared with placebo (2.10; P < 0.0001 for both actives). Minimal itch over all time points was reported by 76.1% of alcaftadine-treated subjects compared with 58.1% of olopatadine-treated subjects (P = 0.0121). Treatment with alcaftadine 0.25% and olopatadine 0.2% was safe and well tolerated; no serious adverse events were reported. Conclusion: Once-daily alcaftadine 0.25% ophthalmic solution demonstrated greater efficacy in prevention of ocular itching compared with olopatadine 0.2% at 3 min post-CAC (primary endpoint), and over all time points, 16 h post-treatment instillation. Alcaftadine and olopatadine both provided effective relief compared with placebo and were generally well tolerated. Electronic supplementary material The online version of this article (doi:10.1007/s12325-014-0155-3) contains supplementary material, which is available to authorized users

Corruption in migration management: a network perspective

This paper explores the relation between networks as an emerging mode of public governance and corruption. Adopting the theoretical lens of actor-network theory (ANT), the paper investigates an Italian episode of corruption related to the awarding of government contracts for the management of the Mineo’s CARA, the Europe's largest reception centre for migrants. The analysis shows that a governance network may turn corruption itself into a network where abuse of power can proliferate thanks to the opacity resulting from the multiplicity of actors, interactions, and fragmentation characterizing the governance system