Akut İskemik İnme Hastalarında Yeni Bir Markır: Monosit / HDL Oranı

Objective: Stroke is a major cause of global morbidity and mortality. Ischemic stroke is usually marked by cell death associated with inflammation and oxidative stress, and the role of inflammation in neurological diseases has become increasingly obvious. In our study, we studied the monocyte / HDL ratio (MHR) which can support the theory of inflammation in stroke and can be used in clinical practice. MHR can be used a prognostic marker in stroke patients base on this theory. Methods: Our study registered 91 acute ischemic stroke patients (47 females and 44 males) and 50 healthy controls. Results: MHR was elevated in the patient group and correlated with high-sensitivity C-reactive protein (hsCRP). MHR was higher in patients with high a National Institutes of Health Stroke Scale (NIHSS) than those with a low NIHSS (p=0.050) as well as in patients with a larger infarct area and in than those with a smaller area (p=0.050). The MHR correlated with both the clinical condition and infarct area in acute ischemic stroke patients, which underscores the value of MHR as a new marker. Conclusions: This cross-sectional study of 91 acute ischemic stroke patients indicates that inflammation markers and MHR are correlated with clinical status and even radiological parameters.Amaç: İnme, dünyada major bir morbidite ve mortalite sebebidir. İskemik inmede genellikle inflamasyon ve oksidatif strese bağlı hücre ölümü görülür. Nörolojik hastalıklarda inflamasyonun rolü giderek daha da belirginleşmektedir. Çalışmamızda inmede inflamasyon teorisini destekleyebilen ve klinik uygulamada kullanılabilecek monosit / HDL oranını (MHO) inceledik. Gereç ve Yöntem: Çalışmamızda 91 akut iskemik inme hastası (47 kadın ve 44 erkek) ve 50 sağlıklı kontrol kaydedildi. Bulgular: Hasta grubunda MHO yüksek idi ve yüksek duyarlılıkta C-reaktif protein (hsCRP) ile korele idi. MHO, Ulusal Sağlık Enstitüleri İnme Ölçeği (NIHSS) skoru yüksek olan hastalarda, düşük NIHSS'li (p = 0.050) olanların yanı sıra, ve de daha büyük bir infarkt alanı olanlarda daha küçük infarkt alanına sahip olanlara (p = 0.050) göre daha yüksekti. MHO, yeni bir belirteç olarak, akut iskemik inme hastalarında, hem klinik durum hem de infarkt alanı ile koreledir. Sonuç: 91 akut iskemik inme hastasının, bu cross-sectional çalışması, inflamasyon belirteçlerinin ve MHO'nin; klinik durum ve hatta radyolojik parametrelerle körele olduğunu göstermektedir

Determining Usage Diversity of Measurement and Evaluation Concepts in the Primary Education Program

DergiPark: 326239trakyasobedThe aim of this research is to determine different concept usages in the field of measurement and evaluation statistically. In accordance with this purpose, of the purposeful sampling methods, criteria sampling is used and 79 articles in 11 journals, which are indexed by ULAKBİLİM in the field of education and whose full texts can be accessible online between the years 2004-2010, composed the sample of the study. As a result of research, it was figured out that Traditional and Alternative Measurement and Evaluation concepts were proportionately stated at most. When the concepts that are used to determine the methods and instruments of measurement and evaluation are analyzed in terms of diversity, usages of Portfolio, Performance Evaluation, Self-Evaluation and Group Evaluation, Peer Evaluation, Rubric, Interview, Checklist and Diagnostic Tree concepts are mostly encounteredAraştırmanın amacı, ölçme ve değerlendirme alanında kullanılan kavramların farklı kullanımlarını istatistiksel olarak belirlemektir. Amaç doğrultusunda ULAKBİM’ de eğitim alanında taranan dergilerden amaçlı örnekleme yöntemlerinden ölçüt örneklem kullanılarak 2004-2010 yılları arasında, çevirim içi olarak tam metinlerine erişilebilen 11 dergide yer alan 79 makale örneklem olarak seçilmiştir. Araştırma sonucunda oransal olarak en fazla Geleneksel ve Alternatif Ölçme ve Değerlendirme olarak ifade edildiği görülmüştür. Ölçme ve değerlendirme yöntem ve araçlarını belirtmek için kullanılan isimlendirmeler çeşitlilik açısından incelendiğinde, en fazla Portfolyo, Performans değerlendirme, Öz Değerlendirme, Grup Değerlendirme, Akran Değerlendirme, Rubrik, Görüşme, Kontrol Listesi ve Tanılayıcı Dallanmış Ağaç kavramlarının kullanımına rastlanmıştı

Comparison of Satisfaction Levels between COVID-19 and Non-COVID-19 Patients in the Emergency Department

Background: Patient satisfaction in the emergency department is an indicator of the quality of healthcare service provided. The increased workload and stress of healthcare workers due to the ongoing pandemic can affect the quality of patient care and thus patient satisfaction. This study compares the satisfaction levels of COVID-19 and non-COVID-19 patients in the emergency department. Tools and Methods: In this prospective, observational survey study, the brief emergency patient satisfaction scale (BEPSS) was used to establish the satisfaction levels of patients. Results: Satisfaction levels were significantly higher, while waiting times were quite shorter for COVID-19 patients than for non-COVID-19 patients. The triage categories had no effect on the satisfaction of non-COVID-19 patients, while satisfaction levels were significantly lower in patients with green triage tags than in those with yellow and red triage tags among the COVID-19 patients. Conclusion: The satisfaction levels of COVID-19 patients were higher than those of non-COVID-19 patients. The short waiting times for COVID-19 patients in the emergency department have a significant impact on patient satisfaction

Patients with primary restless legs syndrome have higher prevalence of autonomic dysfunction and irritable bowel syndrome

CONCLUSION The presence of autonomic nervous system impairment in patients with pRLS and the strong link between IBS and pRLS merit further, more extensive investigation

A Rare Case of Cholestasis: Arthrogryposis, Renal Tubular Disorder and Cholestasis Syndrome

Arthrogryposis, renal tubular dysfunction and cholestasis (ARC) syndrome is a rare, autosomal recessive multisystem disorder. Severe growth retardation, ichthyosis, recurrent febrile disease, platelet abnormalities, sensorineural hearing loss, hypotonia and corpus callosum dysgenesis were later included as further features of this syndrome. We present a case of ARC syndrome diagnosed by genetic analysis

Multiparametric MRI guidance in first-time prostate biopsies: what is the real benefit?

PURPOSEWith the increased recognition of the capabilities of prostate multiparametric (mp) magnetic resonance imaging (MRI), attempts are being made to incorporate MRI into routine prostate biopsies. In this study, we aimed to analyze the diagnostic yield via cognitive fusion, transrectal ultrasound (TRUS)-guided, and in-bore MRI-guided biopsies in biopsy-naive patients with positive findings for prostate cancer screening.METHODSCharts of 140 patients, who underwent transrectal prostate biopsy after the adaptation of mp-MRI into our routine clinical practice, were reviewed retrospectively. Patients with previous negative biopsies (n=24) and digital rectal examination findings suspicious for ≥cT3 prostate cancer (n=16) were excluded. T2-weighted imaging, diffusion-weighted imaging, and dynamic contrast-enhanced imaging were included in mp-MRI. Cognitive fusion biopsies were performed after a review of mp-MRI data, whereas TRUS-guided biopsies were performed blinded to MRI information. In-bore biopsies were conducted by means of real-time targeting under MRI guidance. RESULTSBetween January 2012 and February 2014, a total of 100 patients fulfilling the inclusion criteria underwent TRUS-guided (n=37), cognitive fusion (n=49), and in-bore (n=14) biopsies. Mean age, serum prostate specific antigen level, and prostate size did not differ significantly among the study groups. In TRUS-guided biopsy group, 51.3% were diagnosed with prostate cancer, while the same ratio was 55.1% and 71.4% in cognitive fusion and in-bore biopsy groups, respectively (P = 0.429). Clinically significant prostate cancer detection rate was 69.1%, 70.3%, and 90% in TRUS-guided, cognitive fusion, and in-bore biopsy groups, respectively (P = 0.31). According to histopathologic variables in the prostatectomy specimen, significant prostate cancer was detected in 85.7%, 93.3%, and 100% of patients in TRUS-guided, cognitive fusion, and in-bore biopsy groups, respectively. CONCLUSIONIn the first set of transrectal prostate biopsies, mp-MRI guidance did not increase the diagnostic yield significantly

Direct Health Expenditure Analysis Related to Hearing Loss in Individuals Using Hearing Aids and Cochlear Implants

Objective:This study aimed to investigate the expenditures related to hearing devices and compare the differences in expenditures in child and adult users.Methods:A preliminary questionnaire was developed and conducted amongst hearing aid and cochlear implant users. A total of 178 patients (57.3% were hearing aid users, 42.7% were cochlear implant users) were included in the study and grouped as adults (first group, 50 patients), and children 1< (second group, 123 patients).Results:The results of the study showed that individuals used approximately 4.5% of their annual income as health expenditure related to hearing loss. This rate was over 5% for child users, and about 2.7% for adult users. Moreover, the expenditure made by adult users was below the amount of expenditure made for children in all health expenditure indicators.Conclusion:Supporting the family budget for hearing loss expenditures not covered by the public health insurance will minimize the financial problems caused by the disability