Estudo de genes candidatos envolvidos na resposta à medicação antipsicótica em esquizofrênicos

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Association between grip strength, anthropometric data and functional capacity

The hand is one of the most important instruments of the human body, mainly due to the possibility of grip movements. Grip strength has been described as an important predictor of functional capacity. There are several factors that may influence it, such as gender, age and anthropometric characteristics. Functional capacity refers to the ability to perform daily activities which allow the individual to self-care and to live with autonomy. Composite Physical Function (CPF) scale is an evaluation tool for functional capacity that includes daily activities, self-care, sports activities, upper limb function and gait capacity. In 2011, Portugal had 15% of young population (0-14years) and 19% of elderly population (over 65 years). Considering the double-ageing phenomen, it is important to understand the effect of the grip strength in elderly individuals, considering their characteristics, as the need to maintainin dependency as long as possible

Infrared thermography comparison of heat generation between simplified and conventional implant site preparation techniques

ABSTRACT Introduction: The predictability of osseointegration depends on a non-traumatic surgical technique that maintains cell viability. It is known that during the drilling osteotomy for implant placement occurs heat generation, being able to influence osseointegration due to thermal damage. The objective of this research was to evaluate and compare the heat generated by the drills during the preparation of surgical sites for implant placement between two different techniques: simplified (Simplified Drilling, SD) and conventional, in an in vitro model. Material and methods: Fifty implant site preparations were performed in segments of bovine ribs, divided into two groups, with the respective drill sequences: control group, conventional preparation, Ø2.0mm spear drill and Ø2.15mm, Ø2.85mm, Ø3.35mm, Ø3.85mm twist drills; SD group, Ø2.15mm and Ø3.85mm twist drills. The measurement of the temperature variation generated by each drill in each group was performed by an infrared thermal camera at three points in the bovine rib segment. Results: The temperature variations at one and thirteen millimeters below the drilling site were, respectively, 0.51±0.64°C and 0.46±0.59°C for the control group, and 0.62±0.76°C and 0.5±0.86°C for the SD group. No statistically significant differences were found between the control and SD groups in relation to heat generation in any of the evaluated points; p=0.288 and p=0.584, respectively for analyzes one and thirteen millimeters below the drilling site. Discussion: The technique of implant site preparation can be simplified, using only two drills in this modality, without showing significant differences in relation to heat generation when compared to the conventional preparation technique

Cross-cultural adaptation of the Clear Communication Index to Brazilian Portuguese

OBJECTIVE: To perform a cross-cultural adaptation of the Clear Communication Index instrument from the Centers for Disease Control and Prevention (CDC-CCI) from English to Brazilian Portuguese. METHODS: This study comprised initial discussion about the conceptual equivalence of the instrument by a committee formed by experts on health education. We performed translations, synthesis of translations, back-translations, revision by the committee, and linguistic revision. Semantic equivalence was obtained by analyzing the referential and general meaning of each item by the committee, resulting in a pre-final version of the instrument. Subsequently, thirty professionals with health sciences degrees performed a pre-test. These professionals used the pre-final version of the instrument to assess a health education material. A questionnaire was applied to evaluate the acceptability of the instrument, the understanding of each of the 20 items, as well as the individual and professional variables. We analyzed the scores attributed to the health education material, the variables related to healthcare professionals, the proportions of the acceptability of the instrument, and the comprehension of each item. RESULTS: After we obtained the conceptual equivalence of the instrument, the committee of experts, the instrument’s main author, and the linguist produced the pre-final version using two translations, a synthesis of the translations, and two back-translations. A general equivalence was maintained in 15 of the 20 items (75%), four of the items were slightly altered (20%), and one item was very altered (5%). Nineteen items presented referential equivalence or near equivalence (95%). We then carried out with the pre-test, in which the professionals used the pre-final version. Two items in the domains of “risks” and “main message” were unclear and needed to be revised. CONCLUSION: The process of cross-cultural adaptation of the Clear Communication Index provided an adapted version to the Brazilian Portuguese language

THE NURSING CARE IN OXIDE NITRIC THERAPY IN NEWBORN WITH PULMONARY HYPERTENSION PERSISTENT

This is a literature review on the use of inhaled nitric oxide in the treatment of persistent pulmonary hypertension of the newborn, and to reflect on nursing care of children with persistent pulmonary hypertension undergoing treatment with nitric oxide from the analysis of scientific production of nursing nationally and internationally on this topic. Data were published in the last ten years, in journals indexed in databases: MEDLINE, LILACS, BDENF and SCIELO. After the search with the following keywords: nitric oxide, persistent pulmonary hypertension, neonatal and nursing care, were found 109 publications including 3 fell on the research objective. For analysis of the productions were analyzed to content in the thematic mode, resulting in 3 categories: a) Caution regarding installation and use of equipment, b) Implications for the nursing care of newborns treated with Nitric Oxide c) Assistance nursing the family of the newborn. However, we observed therapy be a relatively new and complex for neonatal nursing with little research conducted by these professional son the topic.Trata-se de uma revisão bibliográfica sobre a utilização do óxido nítrico inalatório no tratamento da hipertensão pulmonar persistente do recém nascido, tendo como objetivo refletir sobre a assistência de enfermagem à criança com hipertensão pulmonar persistente submetida ao tratamento com óxido nítrico a partir da análise da produção científica da enfermagem nacional e internacional acerca desta temática. Os dados analisados foram publicações dos últimos dez anos, em revistas indexadas nas bases de dados: MEDLINE, LILACS, BDENF e SCIELO. Após a busca com os descritores: Óxido Nítrico, hipertensão pulmonar persistente, neonatal e cuidados de enfermagem, foram encontradas 109 publicações das quais 3 se enquadravam no objetivo da pesquisa. Para análise das produções foi adotada a análise de conteúdo na modalidade temática, originando 3 categorias: a) Cuidados quanto à montagem e utilização dos equipamentos; b) Implicações para a Assistência de Enfermagem ao recém-nascido em tratamento com Óxido Nítrico; c) Assistência de enfermagem à família do RN. Contudo, observamos ser uma terapia relativamente recente e complexa para a enfermagem neonatal com poucas pesquisas realizadas por esses profissionais sobre a temática

Evaluation of the implementation of a training referred to pressure injury prevention

Objetivo: avaliar a implementação de um programa de capacitação para medidas de prevenção de lesão por pressão por meio de instrumentos validados. Metodologia: estudo quase-experimental desenvolvido em quatro etapas: validação de conteúdo de um instrumento de auditoria para a avaliação da implementação de medidas de prevenção de lesão por pressão; auditoria para a avaliação da implementação das medidas; intervenção educativa com validação de face de um questionário para avaliar a aprendizagem; repetição da auditoria dois meses após a intervenção educativa. Resultados: a validação alcançou porcentagem de concordância entre os especialistas superior a 0,9. Na primeira auditoria, a conformidade na implementação das medidas foi de 65,1%. A nota da avaliação de aprendizagem antes da intervenção foi 7,99 e, após, 8,45 (p<0,0001). Na segunda auditoria, a conformidade na implementação das medidas foi de 56,2%. Conclusão: a implementação de um programa de capacitação para medidas de prevenção de lesão por pressão contribuiu para aumentar o nível de conhecimento teórico dos participantes, entretanto, não houve a translação do conhecimento adquirido para a prática clínica. A validação dos instrumentos foi satisfatória.Objective: evaluate the implementation of a training program for pressure injury prevention measures, using validated instruments. Methodology: almost experimental study, developed in four stages: validation of the contents of an audit instrument for evaluation of the implementation of pressure injury prevention measures; auditing to evaluate the prevention measures implemented; educational intervention with face validity of a questionnaire to assess learning; repetition of the audit, two months after the educational intervention. Results: the validation reached a percentage of agreement among experts above 0.9. In the first audit, the average of conformities that were found out, was 65.1%. The learning assessment score before the intervention was 7.99 and after 8.45 (p<0.0001). In the second audit, the average of conformities that were found out, was 56.2%. Conclusion: the implementation of a training program for pressure injury prevention measures contributes to increase the participants’ level of knowledge, however, there was no translation of the acquired knowledge into clinical practice. Instrument validation was satisfactory

Quality of hydroponic forage corn cultivated on different by-product substrates

Hydroponic corn cultivation is an efficient, fast, and feasible alternative for periods of food scarcity; however, there is still little information on the qualitative and quantitative parameters of the produced biomass, especially with regard to substrates. This study aimed to evaluate the productive and qualitative aspects of hydroponic feed corn grown on different substrates with a cultivation period of 15 days. Four substrates were evaluated: 1) fermented whole açaí seeds, 2) crushed açaí seeds, 3) sugarcane bagasse, and 4) ground Tifton hay, with five replications under a randomized block design. Substrate temperature was monitored during the production period. After harvesting on day 15, roots length (RL), shoot length (SL), biomass dry matter content (BDM), dry biomass yield, forage dry mass productivity, crude protein (CP), and ash content were assessed. There was no correlation of growth period and substrate temperature. RL was not affected by substrates, BDM was lower in treatment 3, CP was not influenced, and ash content was higher in treatment 1. In general, the best development was observed in treatment 1 because of the absence of distinction regarding qualitative parameters (CP and ash) and higher granulometry of whole açaí seeds which affects mass density and substrate aeration, thus allowing higher dry biomass yield. Keywords: açaí seed; agroindustry by-products; animal nutrition; forage production

Épocas de corte na produtividade e valor proteico de forragem de Chamaecrista rotundifolia.

A Chamaecrista rotundifolia é uma leguminosa com uso potencial para a região amazônica, principalmente para a produção animal, embora ainda pouco estudada. Como é comum em plantas tropicais, a época de corte e consequentemente o avanço da maturidade podem influenciar a qualidade da forragem para os animais, assim, o objetivo foi verificar a produtividade e o valor proteico da. rotundifolia colhida em três estágios de crescimento. O delineamento foi em blocos ao acaso com sete repetições avaliando-se três épocas de corte correlacionadas ao início do florescimento, ao auge da produção de vagens e na fase de dispersão de sementes, que equivaleram cronologicamente a 48, 91 e 133 dias após o transplantio das mudas, respectivamente. A definição da época de corte para essa leguminosa influencia seu valor nutricional e produtividade, sendo a colheita realizada aos 133 dias a mais indicada por conciliar valor produtivo e qualidade forrageira.Chamaecrista rotundifolia is a potential legume for use in Amazon region, mainly forlivestock, although still is little studied. According to characteristics of tropical plant, the cuttingtime and consequent maturity advance can affect quality as an animal food. The aim of this studywas to verify the protein content and productivity of C. rotundifolia harvested in three differentgrowth stages. The experiment was carried out in a randomized block design with seven replicationscomprising three treatments of growth stages corresponding to the begining of flowering, podproduction and seed dispersal which were cronologically equivalent to 48, 91 and 133 days afterseedlings planting. Produtivity and nutritional value offorage from this legume is affected by growthstages C. rotundifolia harvested at 133 days after seedlings planting is indicated by its productiveand qualitative characteristics as forage

Development of Modular Cooling for Water-Cooled Photovoltaic Plant in Real Scale

This chapter evaluates module architectures and units of photovoltaic cooling systems, aiming to determine, select and design a modular system that can be applied in a real-scale photovoltaic power plant (PVPP) in order to enhance the yields of electricity production (entitled cooled photovoltaic plant). An analysis of the local climatic, geographic and solar conditions as well as construction, operational and maintenance aspects was carried out. Worldwide, there are three main types of cooled photovoltaic systems: PVT liquid and air collectors, PV ventilated with heat recovery and non-PVT systems. Based on the local weather conditions (tropical warm and dry) with both temperature and solar irradiation index being high, it results the PVT-liquid system to be more suitable in a scenario with available cooling fluid. We conclude that the best design and arrangement of the cooling system are of the type coil and multiple channel because they permit better rates of heat exchange between the cooling fluid and the PV module

Caracterização da pecuária leiteira de base familiar no Estado do Pará: reflexões sobre práticas agroecológicas

Assumindo a importância da produção leiteira na composição dos sistemas agrícolas familiares de base camponesa, assim como as controvérsias sociais e ambientais que a envolvem, este artigo busca refletir sobre a existência e a prática de sistemas agroecológicos nesta atividade no estado do Pará. A metodologia de trabalho utilizada foi a leitura e reflexão a partir de estudos desenvolvidos envolvendo diversas equipes de pesquisas, incluindo os autores deste artigo, que, ao longo de mais de 20 anos, têm estudado a pecuária leiteira na Amazônia paraense. Como principais resultados, identificamos que não há uma classificação exata para o sistema leiteiro de base familiar na Amazônia paraense, podendo-se dizer apenas que, de uma maneira geral, se trata de sistemas naturais e sem muitos incrementos, fruto da percepção e experiências empíricas dos atores sobre as necessidades de interação visando a produção dentro do novo ecossistema