2,126 research outputs found
Spatio-temporal patterns in the Hantavirus infection
We present a model of the infection of Hantavirus in deer mouse, Peromyscus
maniculatus, based on biological observations of the system in the North
American Southwest. The results of the analysis shed light on relevant
observations of the biological system, such as the sporadical disappearance of
the infection, and the existence of foci or ``refugia'' that perform as
reservoirs of the virus when environmental conditions are less than optimal.Comment: 6 pages, 5 inlined figures, RevTeX 4 forma
Diffusion and Home Range Parameters from Rodent Population Measurements in Panama
Simple random walk considerations are used to interpret rodent population
data collected in Hantavirus-related investigations in Panama regarding the
short-tailed cane mouse, \emph{Zygodontomys brevicauda}. The diffusion constant
of mice is evaluated to be of the order of (and larger than) 200 meters squared
per day. The investigation also shows that the rodent mean square displacement
saturates in time, indicating the existence of a spatial scale which could, in
principle, be the home range of the rodents. This home range is concluded to be
of the order of 70 meters. Theoretical analysis is provided for interpreting
animal movement data in terms of an interplay of the home ranges, the diffusion
constant, and the size of the grid used to monitor the movement. The study
gives impetus to a substantial modification of existing theory of the spread of
the Hantavirus epidemic which has been based on simple diffusive motion of the
rodents, and additionally emphasizes the importance for developing more
accurate techniques for the measurement of rodent movement.Comment: 18 pages, 5 figure
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The View of Russian Students on Whether Psychology is a Science
The Psychology as Science Scale (Friedrich, 1996) was administered to 525 psychology students from nine Russian universities to assess their beliefs about the nature of the discipline. About half of students (49.6%) generally agreed that psychology may be called a scientific discipline. Specifically, 71. 5% of the students agreed that psychology is a natural science, similar to biology, chemistry, and physics, 39. 9% of students agreed that psychological research is important and training in psychological methodology is necessary, and 43.1% of students agreed that human behavior is highly predictable. Students who took three methodology courses shared significantly stronger beliefs in the need for psychological research and the importance of training in methodology compared to students who did not take any methodology courses. Furthermore, students with a specialist degree had significantly stronger beliefs that psychology is a science compared to students who have just finished school. In terms of the effect of students’ career aspirations, students who wanted to be academic psychologists and clinicians had significantly stronger beliefs that psychology is a science compared to students who did not have clarity about their future careers. Regardless of the study limitations, these findings have potential implications for Russian psychology instructors
Multi-objective engineering shape optimization using differential evolution interfaced to the Nimrod/O tool
This paper presents an enhancement of the Nimrod/O optimization tool by interfacing DEMO, an external multiobjective optimization algorithm. DEMO is a variant of differential evolution – an algorithm that has attained much popularity in the research community, and this work represents the first time that true multiobjective optimizations have been performed with Nimrod/O. A modification to the DEMO code enables multiple objectives to be evaluated concurrently. With Nimrod/O’s support for parallelism, this can reduce the wall-clock time significantly for compute intensive objective function evaluations. We describe the usage and implementation of the interface and present two optimizations. The first is a two objective mathematical function in which the Pareto front is successfully found after only 30 generations. The second test case is the three-objective shape optimization of a rib-reinforced wall bracket using the Finite Element software, Code_Aster. The interfacing of the already successful packages of Nimrod/O and DEMO yields a solution that we believe can benefit a wide community, both industrial and academic
Hemodiafiltration Improves Plasma 25-Hepcidin Levels: A Prospective, Randomized, Blinded, Cross-Over Study Comparing Hemodialysis and Hemodiafiltration
Background/Aims: Data from studies comparing the effect of hemodiafiltration (HDF) and conventional hemodialysis (HD) on clinically important outcomes are insufficient to support superiority of HDF. None of these studies has been participant-blinded. Methods: We performed a prospective, randomized, and patient-blinded cross-over study. Twenty patients on chronic HD received either HD for 2 months followed by post-dilution HDF for 2 months or in opposite order. A range of clinical parameters, as well as markers of inflammation, oxidative stress and iron metabolism was measured. Results: The two treatments were similar with respect to dialysis-related complications, quality of life, and the biomarkers of oxidative stress and inflammation. Compared to HD, 25-hepcidin and β2-microglobulin were 38 and 32%, respectively, lower after 60 days of HDF (p Conclusion: In short term, HDF is not superior to HD regarding dialysis-related complications. The higher ESA consumption observed with HDF can be explained by blood clotting in tubing and dialyzers, as more anticoagulation was needed with post-dilution HDF. In a longer perspective, lowering serum hepcidin levels may improve pathological iron homeostasis
Applicability of the Fisher Equation to Bacterial Population Dynamics
The applicability of the Fisher equation, which combines diffusion with
logistic nonlinearity, to population dynamics of bacterial colonies is studied
with the help of explicit analytic solutions for the spatial distribution of a
stationary bacterial population under a static mask. The mask protects the
bacteria from ultraviolet light. The solution, which is in terms of Jacobian
elliptic functions, is used to provide a practical prescription to extract
Fisher equation parameters from observations and to decide on the validity of
the Fisher equation.Comment: 5 pages, 3 figs. include
Fluid physics, thermodynamics, and heat transfer experiments in space
An overstudy committee was formed to study and recommend fundamental experiments in fluid physics, thermodynamics, and heat transfer for experimentation in orbit, using the space shuttle system and a space laboratory. The space environment, particularly the low-gravity condition, is an indispensable requirement for all the recommended experiments. The experiments fell broadly into five groups: critical-point thermophysical phenomena, fluid surface dynamics and capillarity, convection at reduced gravity, non-heated multiphase mixtures, and multiphase heat transfer. The Committee attempted to assess the effects of g-jitter and other perturbations of the gravitational field on the conduct of the experiments. A series of ground-based experiments are recommended to define some of the phenomena and to develop reliable instrumentation
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