45 research outputs found
Localization of Scalar Fluctuations in a Dilatonic Brane-World Scenario
We derive and solve the full set of scalar perturbation equations for a class
of -symmetric five-dimensional geometries generated by a bulk cosmological
constant and by a 3-brane non-minimally coupled to a bulk dilaton field. The
massless scalar modes, like their tensor analogues, are localized on the brane,
and provide long-range four-dimensional dilatonic interactions, which are
generically present even when matter on the brane carries no dilatonic charge.
The shorter-range corrections induced by the continuum of massive scalar modes
are always present: they persist even in the case of a trivial dilaton
background (the standard Randall--Sundrum configuration) and vanishing
dilatonic charges.Comment: 22 pages, late
Fuchs versus Painlev\'e
We briefly recall the Fuchs-Painlev\'e elliptic representation of Painlev\'e
VI. We then show that the polynomiality of the expressions of the correlation
functions (and form factors) in terms of the complete elliptic integral of the
first and second kind,
and , is a straight consequence of the fact that the differential
operators corresponding to the entries of Toeplitz-like determinants, are
equivalent to the second order operator which has as solution (or,
for off-diagonal correlations to the direct sum of and ). We show
that this can be generalized, mutatis mutandis, to the anisotropic Ising model.
The singled-out second order linear differential operator being replaced
by an isomonodromic system of two third-order linear partial differential
operators associated with , the Jacobi's form of the complete elliptic
integral of the third kind (or equivalently two second order linear partial
differential operators associated with Appell functions, where one of these
operators can be seen as a deformation of ). We finally explore the
generalizations, to the anisotropic Ising models, of the links we made, in two
previous papers, between Painlev\'e non-linear ODE's, Fuchsian linear ODE's and
elliptic curves. In particular the elliptic representation of Painlev\'e VI has
to be generalized to an ``Appellian'' representation of Garnier systems.Comment: Dedicated to the : Special issue on Symmetries and Integrability of
Difference Equations, SIDE VII meeting held in Melbourne during July 200
Accretion Disc Theory: From the Standard Model Until Advection
Accretion disc theory was first developed as a theory with the local heat
balance, where the whole energy produced by a viscous heating was emitted to
the sides of the disc. One of the most important new invention of this theory
was a phenomenological treatment of the turbulent viscosity, known as ''alpha''
prescription, when the (r) component of the stress tensor was
approximated by ( P) with a unknown constant . This
prescription played the role in the accretion disc theory as well important as
the mixing-length theory of convection for stellar evolution. Sources of
turbulence in the accretion disc are discussed, including nonlinear
hydrodynamical turbulence, convection and magnetic field role. In parallel to
the optically thick geometrically thin accretion disc models, a new branch of
the optically thin accretion disc models was discovered, with a larger
thickness for the same total luminosity. The choice between these solutions
should be done of the base of a stability analysis. The ideas underlying the
necessity to include advection into the accretion disc theory are presented and
first models with advection are reviewed. The present status of the solution
for a low-luminous optically thin accretion disc model with advection is
discussed and the limits for an advection dominated accretion flows (ADAF)
imposed by the presence of magnetic field are analysed.Comment: Roceeding of the Int. Workshop "Observational Evidence for Black
Holes in the Universe". Calcutta, 11-17 January 1998. Kluwer Acad. Pu
Early
Arthritis Rheum. 2004 Dec;50(12):3934-40.
Early response to immunosuppressive therapy predicts good renal outcome in lupus nephritis: lessons from long-term followup of patients in the Euro-Lupus Nephritis Trial.
Houssiau FA, Vasconcelos C, D'Cruz D, Sebastiani GD, de Ramon Garrido E, Danieli MG, Abramovicz D, Blockmans D, Mathieu A, Direskeneli H, Galeazzi M, Gül A, Levy Y, Petera P, Popovic R, Petrovic R, Sinico RA, Cattaneo R, Font J, Depresseux G, Cosyns JP, Cervera R.
Université Catholique de Louvain, Brussels, Belgium. [email protected]
Abstract
OBJECTIVE: In the Euro-Lupus Nephritis Trial (ELNT), 90 patients with lupus nephritis were randomly assigned to a high-dose intravenous cyclophosphamide (IV CYC) regimen (6 monthly pulses and 2 quarterly pulses with escalating doses) or a low-dose IV CYC regimen (6 pulses of 500 mg given at intervals of 2 weeks), each of which was followed by azathioprine (AZA). After a median followup of 41 months, a difference in efficacy between the 2 regimens was not observed. The present analysis was undertaken to extend the followup and to identify prognostic factors.
METHODS: Renal function was prospectively assessed quarterly in all 90 patients except 5 who were lost to followup. Survival curves were derived using the Kaplan-Meier method.
RESULTS: After a median followup of 73 months, there was no significant difference in the cumulative probability of end-stage renal disease or doubling of the serum creatinine level in patients who received the low-dose IV CYC regimen versus those who received the high-dose regimen. At long-term followup, 18 patients (8 receiving low-dose and 10 receiving high-dose treatment) had developed permanent renal impairment and were classified as having poor long-term renal outcome. We demonstrated by multivariate analysis that early response to therapy at 6 months (defined as a decrease in serum creatinine level and proteinuria <1 g/24 hours) was the best predictor of good long-term renal outcome.
CONCLUSION: Long-term followup of patients from the ELNT confirms that, in lupus nephritis, a remission-inducing regimen of low-dose IV CYC followed by AZA achieves clinical results comparable with those obtained with a high-dose regimen. Early response to therapy is predictive of good long-term renal outcome.
PMID: 15593207 [PubMed - indexed for MEDLINE
Gravitational Lensing by Black Holes
We review the theoretical aspects of gravitational lensing by black holes,
and discuss the perspectives for realistic observations. We will first treat
lensing by spherically symmetric black holes, in which the formation of
infinite sequences of higher order images emerges in the clearest way. We will
then consider the effects of the spin of the black hole, with the formation of
giant higher order caustics and multiple images. Finally, we will consider the
perspectives for observations of black hole lensing, from the detection of
secondary images of stellar sources and spots on the accretion disk to the
interpretation of iron K-lines and direct imaging of the shadow of the black
hole.Comment: Invited article for the GRG special issue on lensing (P. Jetzer, Y.
Mellier and V. Perlick Eds.). 31 pages, 12 figure
Large PT Double Photon Production in Hadronic Collisions - Beyond Leading Logarithm QCD Calculation
Aurenche P, Douiri A, Baier R, Fontannaz M, Schiff D. Large PT Double Photon Production in Hadronic Collisions - Beyond Leading Logarithm QCD Calculation. Zeitschrift für Physik C: Particles and fields. 1985;29(3):459-475
Blepharophimosis, ptosis, epicanthus inversus syndrome with translocation and deletion at chromosome 3q23 in a black African female
Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) is a rare autosomal dominant disorder whose main features are the abnormal shape, position and alignment of the eyelids. Type I refers to BPES with female infertility from premature ovarian failure while type II is limited to the ocular features. A causative gene, FOXL2, has been localized to 3q23. We report a black female who carried a de novo chromosomal translocation and 3.13 Mb deletion at 3q23, 1.2 Mb 5' to FOXL2. This suggests the presence of distant cis regulatory elements at the extended FOXL2 locus. In spite of 21 protein coding genes in the 3.13 Mb deleted segment, the patient had no other malformation and a strictly normal psychomotor development at age 2.5 years. Our observation confirms panethnicity of BPES and adds to the knowledge of the complex cis regulation of human FOXL2 gene expression. © 2012 Elsevier Masson SAS.SCOPUS: ar.jinfo:eu-repo/semantics/publishe