7 research outputs found

    The susceptibility of Escherichia coli strains to essential oils of Rormarinus officinalis and Eucalyptus globulus

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    Essential oils are frequently used for flavour and fragrance in the perfume, pharmaceutical, cosmetic and food industries. They are also suitable raw material for production of new synthetic agents. The antibacterial activity of the essential oils obtained by steam distillation of Rosmarinus officinalis L and Eucalyptus globules collected in south Morocco was studied by micro-atmospheric technique against Escherichia coli CIP54127 and E. coli isolated from urine and resistant to several antibiotics. Both essential oils were effective against the two strains bacteria in particularly against E. coli CIP54127. MIQ of both oils ranged from 60 to 70 ìl for both bacteria. In conclusion, results show that essential oils are effective and could be considered as a natural antimicrobial source that can be used on production of natural antimicrobial agents

    LE DOSAGE DE L’HEMOGLOBINE GLYQUEE POUR UNE MEILLEURE SURVEILLANCE DE L’EQUILIBRE GLYCEMIQUE CHEZ L’ENFANT. ETUDE CHEZ 55 ENFANTS

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    The diabetic patients treatments need to be continuously adjusted by frequent urinary glucose controls (3-4 times/day and 1 time/month). The repetition of such tests is not accepted by the child and that is a timely diabetic balance reflection. The purpose of this work is to verify the prognostic value of the glycated hemoglobin test, which occurs every eight weeks, in the monitoring of the diabetic child balance. We used for this study a sample of 27 control children and 28 diabetics children followed in the diabete pediatric unit at the hospital Sid' Soufi in Casablanca. In this sample were churched the correlations between the glycated hemoglobin and the fasting blood glucose, the 24 hours glucosuries, the semi-quantitative glucosuries, the cholesterol and the triglycerides blood levels. Our results showed a significant correlation between the level of glycated hemoglobin and all the constants tested except the cholesterol. We concluded that the test of the glycated hemoglobin is a reliable method of glycemia balance monitoring in diabetic child.Les traitements utilisés chez le diabétique ont besoin d’être réajustés de façon continue par des contrôles urinaires fréquents de la glycémie (3- 4 fois/jour et 1 fois/mois). La répétition de ces contrôles est mal acceptée par l’enfant et par sa famille ; d’autant plus que ce n’est qu’un reflet ponctuel de l'équilibre diabétique. L’objet de ce travail est de vérifier la valeur pronostique du dosage de l'hémoglobine glyquée, qui a lieu seulement toutes les huit semaines, dans la surveillance de l’équilibre diabétique de l’enfant. Nous avons utilisé pour cette étude un échantillon de 27 enfants contrôles et 28 enfants diabétiques suivis dans l'unité de diabétologie du service de pédiatrie de l'hôpital Sid' Soufi à Casablanca. Sur cet échantillon, ont été recherché la corrélation entre l’hémoglobine glyquée et la glycémie à jeun, les glucosuries sur 24 heures, les glucosuries semi-quantitatives antérieures au dosage de l’hémoglobine glyquée, le taux de cholestérol et des triglycérides dans le sang. Nos résultats ont montré une corrélation significative entre le taux de l’hémoglobine glyquée et toutes les constantes testées sauf le cholestérol. Nous avons conclu que le test de l’hémoglobine glyquée est une méthode de surveillance fiable et bien adaptée au contrôle de l’équilibre diabétique chez l’enfant

    Toxicity of south Morocco Rosmarinus officinalis essential oil: antibacterial and histopathological effects

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    Le romarin (Rosmarinus officinalis) possède de nombreuses propriétés médicinales. Il est connu pour ses effets antimicrobiens et anti-oxydatifs. Le but de ce travail est d’étudier la toxicité de son huile essentielle (HE) via un test antibactérien selon la technique de micro-atmosphère et un autre histopathologique au niveau des organes de souris (Swiss albinos). L’analyse de la composition chimique de cette HE a été effectuée par CPG. Les constituants majoritaires de l’HE de R. officinalis sont le 1,8-cinéole (42%), l’alpha-pinène (11,92%) et le camphre (13.99%). Les quantités minimales inhibitrices des souches bactériennes testées varient entre 40 ?l et 90 ?l. Au plan histopathologique, une dilatation des alvéoles pulmonaires et une hypertrophie des cellules corticales et médullaires des surrénales ont été relevées. En conclusion, l’HE de R. officinalis ne présente pas de toxicité à la dose 50 ?l/g mais possède des effets stimulants des glandes surrénales et du système respiratoire

    Prokinéticines

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    International audienceGestational trophoblastic disease (MGT) includes a wide spectrum of pathologies of the placenta, ranging from benign precancerous lesions, with gestational trophoblastic tumors. Metastases are the leading causes of death as a result of this tumor. They represent a major problem for obstetrics and for the public health system. To date, there is no predictor of the progression of molar pregnancies to gestational trophoblastic tumor (GTT). Only an unfavorable plasma hCG monitoring after evacuation of hydatidiform mole is used to diagnose a TTG. The causes of the development of this cancer are still poorly understood. Increasing data in the literature suggests a close association between the development of this tumor and poor placental vascularization during the first trimester of pregnancy. The development of the human placenta depends on a coordination between the trophoblast and endothelial cells. A disruption in the expression of angiogenic factors could contribute to uterine or extra-uterine tissue invasion by extravillous trophoblast, contributing to the development of TTG. This review sheds lights on the phenomenon of angiogenesis during normal and abnormal placentation, especially during the MGT and reports preliminary finding concerning, the variability of expression of "Endocrine Gland-Derived Vascular Endothelial Growth Factor" (EG-VEGF), a specific placental angiogenic factor, in normal and molar placentas, and the potential role of differentiated expressions of the main placental angiogenic factors in the scalability of hydatidiform moles towards a recovery or towards the development of gestational trophoblastic tumor. Deciphering the mechanisms by which the angiogenic factor influences these processes will help understand the pathophysiology of MGT and to create opportunities for early diagnosis and treatment of the latter
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