Research in Support of NASA Extreme Environment Mission Operations (NEEMO) 19 Mission

Research in Support of NASA Extreme Environment Mission Operations (NEEMO) 19 Mission Victoria C. Barkley, Ashley Hollis-Bussey, Carolyn E. Newton, Holly Abernethy, and Jason P. Kring In September 2014, over 25 students from multiple departments at Embry-Riddle Aeronautical University (ERAU) participated in the 19th mission of NASA’s Extreme Environment Mission Operations (NEEMO) program. During the mission, astronauts from NASA, Canada, and Europe lived and worked underwater inside the Aquarius facility in the Florida Keys. As an enclosed environment, about the size of a school bus, and deployed 60 feet beneath the surface, Aquarius is an excellent analog of the isolation and confinement astronauts experience aboard the International Space Station or, one day, a vehicle destined for Mars. ERAU students were involved in 3 key projects that occurred during the NEEMO 19 mission. First, engineering students, working with the company Teledyne Oil & Gas, helped design, build, and then deploy a structure for underwater testing of electronic and power cables called the Collaborative Oceanic Reliability Analysis Lab (CORAL). Second, math students conducted tests of navigation and operational capabilities for an underwater autonomous vehicle called “Eco-Dolphin.” Third, human factors and commercial space operations students observed NEEMO mission operations and gained familiarity with communication, scheduling, and coordination during space missions. The endeavor was a successful example of cooperation between academia, industry, and government with ERAU, Teledyne, and NASA students and personnel working together on the three projects. Plans are already underway for an expanded series of projects for the NEEMO 20 mission slated for July of 2015

Asynchronous video messaging promotes family involvement and mitigates separation in neonatal care

From BMJ via Jisc Publications RouterVoR closed-deposited 2020-09-16; AM deposited OA 2020-12-01.Objective: To evaluate the parent and staff experience of a secure video messaging service as a component of neonatal care. Design: Multicentre evaluation incorporating quantitative and qualitative items. Setting: Level II and level III UK neonatal units. Population: Families of neonatal inpatients and neonatal staff. Intervention: Use of a secure, cloud-based asynchronous video messaging service to send short messages from neonatal staff to families. Evaluation undertaken July–November 2019. Main outcome measures: Parental experience, including anxiety, involvement in care, relationships between parents and staff, and breastmilk expression. Results: In pre-implementation surveys (n=41), families reported high levels of stress and anxiety and were receptive to use of the service. In post-implementation surveys (n=42), 88% perceived a benefit of the service on their neonatal experience. Families rated a positive impact of the service on anxiety, sleep, family involvement and relationships with staff. Qualitative responses indicated enhanced emotional closeness, increased involvement in care and a positive effect on breastmilk expression. Seventy-seven post-implementation staff surveys were also collected. Staff rated the service as easy to use, with minimal impact on workload. Seventy-one percent (n=55) felt the service had a positive impact on relationships with families. Staff identified the need to manage parental expectations in relation to the number of videos that could be sent. Conclusions: Asynchronous video messaging improves parental experience, emotional closeness to their baby and builds supportive relationships between families and staff. Asynchronous video supports models of family integrated care and can mitigate family separation, which could be particularly relevant during the COVID-19 pandemic.https://doi.org/10.1136/archdischild-2020-319353106pubpub

The Ursinus Weekly, May 1, 1975

S.F.A.R.C. update • Meistersingers: More than music • USGA questionnaire encourages response • New Yorker critic graduation speaker • Medical school entrances • How to succeed debuts tomorrow in Bearpit • Editorial: Disgust: By the students, of the students! • Letters to the editor: Meekness? • Alumni meet • Feminism: Where? • Inexpensive or just plain cheap • Actors comment • Conflict simulation activities • 2 games, 2 losses • Tennis time • Intramurals • Focus: Steve Fisher • Flyers go for cup! • Lacrosse lookout • Requesthttps://digitalcommons.ursinus.edu/weekly/1037/thumbnail.jp

Clinical Outcomes by Race and Ethnicity in the Systolic Blood Pressure Intervention Trial (SPRINT): A Randomized Clinical Trial

BACKGROUND: The Systolic Blood Pressure Intervention Trial (SPRINT) showed that targeting a systolic blood pressure (SBP) of ≤ 120 mm Hg (intensive treatment) reduced cardiovascular disease (CVD) events compared to SBP of ≤ 140 mm Hg (standard treatment); however, it is unclear if this effect is similar in all racial/ethnic groups. METHODS: We analyzed SPRINT data within non-Hispanic White (NHW), non-Hispanic Black (NHB), and Hispanic subgroups to address this question. High-risk nondiabetic hypertensive patients (N = 9,361; 30% NHB; 11% Hispanic) 50 years and older were randomly assigned to intensive or standard treatment. Primary outcome was a composite of the first occurrence of a myocardial infarction, acute coronary syndrome, stroke, decompensated heart failure, or CVD death. RESULTS: Average postbaseline SBP was similar among NHW, NHB, and Hispanics in both treatment arms. Hazard ratios (HRs) (95% confidence interval) (intensive vs. standard treatment groups) for primary outcome were 0.70 (0.57–0.86), 0.71 (0.51–0.98), 0.62 (0.33–1.15) (interaction P value = 0.85) in NHW, NHB, and Hispanics. CVD mortality HRs were 0.49 (0.29–0.81), 0.77 (0.37–1.57), and 0.17 (0.01–1.08). All-cause mortality HRs were 0.61 (0.47–0.80), 0.92 (0.63–1.35), and 1.58 (0.73–3.62), respectively. A test for differences among racial/ethnic groups in the effect of treatment assignment on all-cause mortality was not significant (Hommel-adjusted P value = 0.062) after adjustment for multiple comparisons. CONCLUSION: Targeting a SBP goal of ≤ 120 mm Hg compared to ≤ 140 mm Hg led to similar SBP control and was associated with similar benefits and risks among all racial ethnic groups, though NHBs required an average of ~0.3 more medications

Suboptimal herd performance amplifies the spread of infectious disease in the cattle industry

Farms that purchase replacement breeding cattle are at increased risk of introducing many economically important diseases. The objectives of this analysis were to determine whether the total number of replacement breeding cattle purchased by individual farms could be reduced by improving herd performance and to quantify the effects of such reductions on the industry-level transmission dynamics of infectious cattle diseases. Detailed information on the performance and contact patterns of British cattle herds was extracted from the national cattle movement database as a case example. Approximately 69% of beef herds and 59% of dairy herds with an average of at least 20 recorded calvings per year purchased at least one replacement breeding animal. Results from zero-inflated negative binomial regression models revealed that herds with high average ages at first calving, prolonged calving intervals, abnormally high or low culling rates, and high calf mortality rates were generally more likely to be open herds and to purchase greater numbers of replacement breeding cattle. If all herds achieved the same level of performance as the top 20% of herds, the total number of replacement beef and dairy cattle purchased could be reduced by an estimated 34% and 51%, respectively. Although these purchases accounted for only 13% of between-herd contacts in the industry trade network, they were found to have a disproportionately strong influence on disease transmission dynamics. These findings suggest that targeting extension services at herds with suboptimal performance may be an effective strategy for controlling endemic cattle diseases while simultaneously improving industry productivity

Determining the pattern and prevalence of alcohol consumption in pregnancy by measuring biomarkers in meconium

Objective: To investigate the feasibility of determining the pattern and prevalence of alcohol consumption in pregnancy by measuring ethanol biomarkers in meconium. Design: Population-based observational study. Setting: Inner-city maternity unit in Scotland, UK. Population: Random sample of singleton infants delivered after 36 completed weeks’ gestation. Methods: Fatty acid ethyl esters (FAEEs) and ethyl glucuronide (EtG) in meconium were measured by liquid chromatography-mass spectroscopy. Samples were frozen at −20°C before analysis. Results were compared anonymously with demographic data including maternal age, parity, smoking, ethnicity and postcode and with infant gestation, birth weight and head circumference. Written informed consent was obtained from all subjects. Results: 235 samples of meconium were analysed (70% of eligible babies). Only four (1%) of mothers declined to participate. FAAEs were detected in all, including four samples below the limit of quantification (10 ng/g). 98 (42%) samples had FAEE concentrations >600 ng/g. EtG was detectable in 93 (40%) samples; in 35 (15%) EtG concentration was >30 ng/g. No mother reported heavy alcohol consumption in pregnancy. FAAE concentration correlated with EtG (Pearson’s coefficient; p<0.001). There was no association between either biomarker and maternal age, parity, smoking, ethnicity or postcode, or infant gestation, birth weight or head circumference. Conclusion: Measurement of ethanol biomarkers in meconium is a feasible tool for determining the pattern and prevalence of alcohol consumption in pregnancy. Data suggest that at least 15% of pregnant women in the west of Scotland are consuming significant quantities of alcohol during latter pregnancy

Student Projects in Support of NASA’s Extreme Environment Mission Operations (NEEMO) Program

Student Projects in Support of NASA’s Extreme Environment Mission Operations (NEEMO) Program Carolyn E. Newton, Victoria C. Barkley, Ashley Hollis-Bussey, Holly Abernethy, and Jason P. Kring In September 2014, over 25 students from multiple departments at Embry-Riddle Aeronautical University (ERAU) participated in the 19th mission of NASA’s Extreme Environment Mission Operations (NEEMO) program. During the mission, astronauts from NASA, Canada, and Europe lived and worked underwater inside the Aquarius facility in the Florida Keys. As an enclosed environment, about the size of a school bus, and deployed 60 feet beneath the surface, Aquarius is an excellent analog of the isolation and confinement astronauts experience aboard the International Space Station or, one day, a vehicle destined for Mars. ERAU students were involved in 3 key projects that occurred during the NEEMO 19 mission. First, engineering students, working with the company Teledyne Oil & Gas, helped design, build, and then deploy a structure for underwater testing of electronic and power cables called the Collaborative Oceanic Reliability Analysis Lab (CORAL). Second, math students conducted tests of navigation and operational capabilities for an underwater autonomous vehicle called “Eco-Dolphin.” Third, human factors and commercial space operations students observed NEEMO mission operations and gained familiarity with communication, scheduling, and coordination during space missions. The endeavor was a successful example of cooperation between academia, industry, and government with ERAU, Teledyne, and NASA students and personnel working together on the three projects. Plans are already underway for an expanded series of projects for the NEEMO 20 mission slated for July of 2015