Proton Decay from Excited States in Spherical Nuclei

Based on a single particle model which describes the time evolution of the wave function during tunneling across a one dimensional potential barrier we study the proton decay of $^{208}$Pb from excited states with non-vanishing angular momentum $\ell$. Several quantities of interest in this process like the decay rate $\lambda$, the period of oscillation $T_{osc}$, the transient time $t_{tr}$, the tunneling time $t_{tun}$ and the average value of the proton packet position $r_{av}$ are computed and compared with the WKB results.Comment: 12 pages, 4 figure

Energy averages and fluctuations in the decay out of superdeformed bands

We derive analytic formulae for the energy average (including the energy average of the fluctuation contribution) and variance of the intraband decay intensity of a superdeformed band. Our results may be expressed in terms of three dimensionless variables: $\Gamma^{\downarrow}/\Gamma_S$, $\Gamma_N/d$, and $\Gamma_N/(\Gamma_S+\Gamma^{\downarrow})$. Here $\Gamma^{\downarrow}$ is the spreading width for the mixing of a superdeformed (SD) state $|0>$ with the normally deformed (ND) states $|Q>$ whose spin is the same as $|0>$'s. The $|Q>$ have mean level spacing $d$ and mean electromagnetic decay width $\Gamma_N$ whilst $|0>$ has electromagnetic decay width $\Gamma_S$. The average decay intensity may be expressed solely in terms of the variables $\Gamma^{\downarrow}/\Gamma_S$ and $\Gamma_N/d$ or, analogously to statistical nuclear reaction theory, in terms of the transmission coefficients $T_0(E)$ and $T_N$ describing transmission from the $|Q>$ to the SD band via $|0\angle$ and to lower ND states. The variance of the decay intensity, in analogy with Ericson's theory of cross section fluctuations depends on an additional variable, the correlation length \Gamma_N/(\Gamma_S+\Gamma^{\downarrow})=\frac{d}{2\pi}T_N/(\Gamma_S+\Gamma^{\d ownarrow}). This suggests that analysis of an experimentally obtained variance could yield the mean level spacing $d$ as does analysis of the cross section autocorrelation function in compound nuclear reactions. We compare our results with those of Gu and Weidenm\"uller.Comment: revtex4, 14 pages, 4 figures, to appear in Physical Review

Metabolic effects of darunavir/ritonavir versus atazanavir/ritonavir in treatment-naive, HIV Type 1-infected subjects over 48 weeks

We assessed metabolic changes for darunavir/ritonavir (DRV/r) once daily (qd) versus atazanavir/ritonavir (ATV/r) qd with fixed-dose tenofovir/emtricitabine. This was a phase 4, multicenter, open-label, randomized exploratory study. Treatment-naive, HIV-1-infected adults received DRV/r 800/100 mg qd or ATV/r 300/100 mg qd, both with emtricitabine/tenofovir 200/300 mg qd. Primary end point: change in triglyceride levels from baseline to week 12. Secondary end points: week 12 and week 48 changes in lipid parameters, insulin sensitivity, inflammatory/coagulation/bacterial translocation biomarkers, viral load, CD4(+) cell count, and week 48 changes in adipose tissue distribution and subjects' perceptions of body changes. In the DRV/r arm, 32/34 and 29/34 subjects completed weeks 12 and 48, respectively; in the ATV/r arm, 30/31 and 25/31 subjects completed weeks 12 and 48, respectively. Small changes in lipid parameters from baseline to weeks 12 and 48 were observed in both arms. Differences were noted between arms in mean changes in total cholesterol (DRV/r, 20.3 mg/dl; ATV/r, 4.6 mg/dl) and apolipoprotein A1 (DRV/r, 10.7 mg/dl; ATV/r, –0.7 mg/dl) at week 12. At week 48, no clinically relevant differences between arms were noted for changes in any lipid parameter, fasting glucose, or insulin sensitivity. Biomarkers generally decreased and efficacy parameters improved in both arms over 48 weeks. Changes in adipose tissue were small and comparable between arms. Subjects' perceptions of body changes generally improved in both study arms. This first pilot comparison in HIV-1-infected subjects suggests that DRV/r has a metabolic profile similar to ATV/r over 48 weeks of treatment. Further randomized studies are warranted

Local Spectral Density for a Periodically Driven System of Coupled Quantum States with Strong Imperfection in Unperturbed Energies

A random matrix theory approach is applied in order to analyze the localization properties of local spectral density for a generic system of coupled quantum states with strong static imperfection in the unperturbed energy levels. The system is excited by an external periodic field, the temporal profile of which is close to monochromatic one. The shape of local spectral density is shown to be well described by the contour obtained from a relevant model of periodically driven two-states system with irreversible losses to an external thermal bath. The shape width and the inverse participation ratio are determined as functions both of the Rabi frequency and of parameters specifying the localization effect for our system in the absence of external field.Comment: 6 pages, 5 figures, submitted to Optics and Spectroscop

A measure of majorisation emerging from single-shot statistical mechanics

The use of the von Neumann entropy in formulating the laws of thermodynamics has recently been challenged. It is associated with the average work whereas the work guaranteed to be extracted in any single run of an experiment is the more interesting quantity in general. We show that an expression that quantifies majorisation determines the optimal guaranteed work. We argue it should therefore be the central quantity of statistical mechanics, rather than the von Neumann entropy. In the limit of many identical and independent subsystems (asymptotic i.i.d) the von Neumann entropy expressions are recovered but in the non-equilbrium regime the optimal guaranteed work can be radically different to the optimal average. Moreover our measure of majorisation governs which evolutions can be realized via thermal interactions, whereas the nondecrease of the von Neumann entropy is not sufficiently restrictive. Our results are inspired by single-shot information theory.Comment: 54 pages (15+39), 9 figures. Changed title / changed presentation, same main results / added minor result on pure bipartite state entanglement (appendix G) / near to published versio

Calculation of the photoionization with de-excitation cross sections of He and helium-like ions

We discuss the results of the calculation of the photoionization with de-excitation of excited He and helium-like ions Li$^{+}$ and B$^{3+}$ at high but non-relativistic photon energies $\omega$. Several lower $^{1}S$ and $^{3}S$ states are considered. We present and analyze the ratios $R_{d}^{+\ast}$ of the cross sections of photoionization with de-excitation, $\sigma_{(d)}^{+\ast}(\omega)$, and of the photo-ionization with excitation, $\sigma ^{+\ast}(\omega)$. The dependence of $R_{d}^{+\ast}$ on the excitation of the target object and the charge of its nucleus is presented. Apart to theoretical interest, results obtained can be verified using such long living excited state as $2^{3}S$ of He.Comment: 10 pages, 6 table

Suggestive Linkage Detected for Blood Pressure Related Traits on 2q and 22q in the Population on the Samoan Islands

Background High blood pressure or hypertension is a major risk factor involved in the development of cardiovascular diseases. We conducted genome-wide variance component linkage analyses to search for loci influencing five blood pressure related traits including the quantitative traits systolic blood pressure (SBP), diastolic blood pressure (DBP) and pulse pressure (PP), the dichotomous trait hypertension (HT) and the bivariate quantitative trait SBP-DBP in families residing in American Samoa and Samoa, as well as in the combined sample from the two polities. We adjusted the traits for a number of environmental covariates such as smoking, alcohol consumption, physical activity and material life style. Results We found suggestive univariate linkage for SBP on chromosome 2q35-q37 (LOD 2.4) and for PP on chromosome 22q13 (LOD 2.2), two chromosomal regions that recently have been associated with SBP and PP, respectively. Conclusion We have detected additional evidence for a recently reported locus associated with SBP on chromosome 2q and a susceptibility locus for PP on chromosome 22q. However, differences observed between the results from our three partly overlapping genetically homogenous study samples from the Samoan islands suggest that additional studies should be performed in order to verify these results

Quantum Fluctuation Theorems

Recent advances in experimental techniques allow one to measure and control systems at the level of single molecules and atoms. Here gaining information about fluctuating thermodynamic quantities is crucial for understanding nonequilibrium thermodynamic behavior of small systems. To achieve this aim, stochastic thermodynamics offers a theoretical framework, and nonequilibrium equalities such as Jarzynski equality and fluctuation theorems provide key information about the fluctuating thermodynamic quantities. We review the recent progress in quantum fluctuation theorems, including the studies of Maxwell's demon which plays a crucial role in connecting thermodynamics with information.Comment: As a chapter of: F. Binder, L. A. Correa, C. Gogolin, J. Anders, and G. Adesso (eds.), "Thermodynamics in the quantum regime - Fundamental Aspects and New Directions", (Springer International Publishing, 2018

Quasiclassical double photoionization from the 2^{1,3}S excited states of helium including shakeoff

We account for the different symmetries of the 2^{1,3}S helium excited states in a quasiclassical description of the knockout mechanism augmented by a quantum shakeoff contribution. We are thus able to formulate the separate contribution of the knockout and shakeoff mechanisms for double photoionization for any excess energy from the 2^{1,3}S states. Photoionization ratios and singly differential cross sections calculated for the 2^{1,3}S excited states of helium are found to be in very good agreement with recent theoretical results.Comment: 9 pages, 5 figure

HIV policy: the path forward--a joint position paper of the HIV Medicine Association of the Infectious Diseases Society of America and the American College of Physicians.

Executive Summary The American College of Physicians (ACP) and the Infectious Diseases Society of America (IDSA) have jointly published 3 policy statements on AIDS, the first in 1986 [1], the second in 1988 [2], and the third in 1994 [3]. In 2001, the IDSA created the HIV Medicine Association (HIVMA), and this updated policy paper is a collaboration between the ACP and the HIVMA of the IDSA. Since the last statement, many new developments call for the need to reexamine and update our policies relating to HIV infection. First, there have been major advances in treatment for HIV infection that have transformed HIV/AIDS from a terminal illness to a chronic disease for many of those who have access to potent therapies and expert medical care [4]. Second, there has been a profound expansion and intensification of the global HIV pandemic, particularly in sub-Saharan Africa, coupled with significant US leadership and resources aimed at providing prevention and care services to affected populations in developing countries. Third, the concerns that were prevalent in the mid-1990s regarding the possibility of HIV transmission in health care settings have ultimately proven to be unfounded as the result of the adoption of universal precautions in those settings. In this article, we emphasize the public health and clinical imperatives for earlier identification of persons with HIV infection; the urgent need to expand access to state-of-the-art HIV care and treatment for infected individuals; the need for access to comprehensive prevention and education for those living with and those at risk for HIV infection; and the need for stronger national leadership to respond to the HIV epidemic in the United States and in the developing world. In December 2008, the ACP and HIVMA released a guidance statement on screening for HIV infection in health care settings that recommended that clinicians adopt routine screening for HIV infection and encourage patients to be tested. Also included in the guidance statement is a recommendation that clinicians determine the need for additional screening on an individual basis