33 research outputs found

    Chemical and Electrochemical studies on the corrosion of mild-steel, copper and zinc in 0. 5 M H2SO4 solution in presence of Azithromycin as effective corrosion inhibitor

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    Azithromycin has been tested as inhibitor for steel, copper and zinc corrosion in 0.5 M H2SO4 was studied using potentiodynamic polarization and electrochemical impedance spectroscopy.  The results showed that the inhibition efficiency increased with increasing the concentration of Azithromycin. The adsorption characteristics of Azithromycin in presence of steel, copper and zinc metals were studied and the data  found to fit the Kinetic-Thermodynamic model. IR spectroscopy of the corrosion product with the inhibitor confirmed the formation of metal ion inhibitor complex

    Publicly available ex vivo transcriptomics datasets to explore CNS physiology and neurodegeneration: state of the art and perspectives

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    The central nervous system (CNS) is characterized by an intricate composition of diverse cell types, including neurons and glia cells (astrocytes, oligodendrocytes, and microglia), whose functions may differ along time, between sexes and upon pathology. The advancements in high-throughput transcriptomics are providing fundamental insights on cell phenotypes, so that molecular codes and instructions are ever more described for CNS physiology and neurodegeneration. To facilitate the search of relevant information, this review provides an overview of key CNS transcriptomics studies ranging from CNS development to ageing and from physiology to pathology as defined for five neurodegenerative disorders and their relative animal models, with a focus on molecular descriptions whose raw data were publicly available. Accurate phenotypic descriptions of cellular states correlate with functional changes and this knowledge may support research devoted to the development of therapeutic strategies supporting CNS repair and function

    Therapeutic Comparison Between Alcoholic and Aqueous Plant Extract of Tannins with Metronidazole in Experimentally Infected Laboratory Mice Cryptosporidium parvum Oocysts

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    The current study was conducted during the period between from the beginning of October 2021 until the end of March 2022. The aim of the study was to measure the therapeutic efficacy of alcoholic and aqueous extracts from the local tannins Cupressus sempervirens for the treatment of experimental infected laboratory mice with Cryptosporidiosis. Through a significant decrease in the number of Oocyst of the parasite that causes infection Cryptosporidium parvum after oral administration of the aqueous and alcoholic extracts with three concentrations (2, 1.3, 1) mg/ml compared to MTZ drug, as the alcoholic extract proved its efficacy by stopping the shedding of parasite Oocyst at the ninth day of treatment with its total absence on the eleventh day of treatment, while the shedding of parasite Oocysts in the group treated with aqueous extract stopped on the eleventh day and completely absent on the thirteenth day of infection

    Evaluation of the Therapeutic Efficacy of Alcoholic Extract of Tannins (Before and After Acidosis) on Laboratory Mice Experimentally Infected with the Parasite Cryptosporidium parvum

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    Plants extracts are the one of the most important sources that have been used in both ancient and recent to many facture variants, types of medical drugs  and that was the aim of the current study to find safe, effective and available natural alternatives by measuring the therapeutic effect of the alcoholic extract of tannins before and after the acid hydrolysis of the extract, in laboratory mice experimentally infected with C. parvum  and using three therapeutic concentrations (2, 1.3, 1) mg / ml, and the alcoholic extract before the acid hydrolysis proved  its therapeutic efficacy with a noticeable decrease in the number of Oocyst  excreted with the feces, as the Oocyst were no longer excreted from the ninth day of the treatment. Parasite Oocyst on the fifth day of treatment were treated by oral administration of the extract in infected mice, in the other hand the current study recorded that Cryptosporidiais as a common disease in the study area, with infection rate of 26%

    Appraisal on Workforce Performance towards Industrialised Building System in Perak, Malaysia

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    The workforce has always been the backbone of the construction industry in the Industrialised Building System (IBS). Previous researchers often obtain data and opinions from the perspective of construction professionals and often neglect the labour workforce opinion. This study aims to investigate various factors that affect the workforce's productivity in IBS performance. The data collection amounts 60 targeted respondents. This study found a strong correlation between motivation, education, and workforce skill level that affects productivity in implementing IBS. The resolution is to propose an improvement of monetary incentive and academic level of the workforce. Keywords: Workforce; Industrialised Building System (IBS); Construction Industry; Malaysia eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/ebpj.v6i18.306

    The Role of IgLON Cell Adhesion Molecules in Neurodegenerative Diseases

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    In the brain, cell adhesion molecules (CAMs) are critical for neurite outgrowth, axonal fasciculation, neuronal survival and migration, and synapse formation and maintenance. Among CAMs, the IgLON family comprises five members: Opioid Binding Protein/Cell Adhesion Molecule Like (OPCML or OBCAM), Limbic System Associated Membrane Protein (LSAMP), neurotrimin (NTM), Neuronal Growth Regulator 1 (NEGR1), and IgLON5. IgLONs exhibit three N-terminal C2 immunoglobulin domains; several glycosylation sites; and a glycosylphosphatidylinositol anchoring to the membrane. Interactions as homo- or heterodimers in cis and in trans, as well as binding to other molecules, appear critical for their functions. Shedding by metalloproteases generates soluble factors interacting with cellular receptors and activating signal transduction. The aim of this review was to analyse the available data implicating a role for IgLONs in neuropsychiatric disorders. Starting from the identification of a pathological role for antibodies against IgLON5 in an autoimmune neurodegenerative disease with a poorly understood mechanism of action, accumulating evidence links IgLONs to neuropsychiatric disorders, albeit with still undefined mechanisms which will require future thorough investigations

    Prediction Fatigue Life of Aluminum Alloy 7075 T73 Using Neural Networks and Neuro-Fuzzy Models

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    In present paper the fatigue life of aluminum alloy 7075 T73 under constant amplitude loading is predicted using ANN and ANFIS models. Many neural networks models are used for this purpose and also different neuro-fuzzy models are built for predict fatigue life.Theclassical power law formula ismost common used to find fatigue behaviors of materials. In present study, two techniques are used to find coefficients of the formula linear and nonlinear regression. Forcomparison the fatigue life curves of soft computing methods are plotted together with two conventionalmethods. The neural network and neuro-fuzzy models give good results compared with two conventional methods. Also it is shown thatneural network model which is trained using Levenberg-Marquardt algorithm is best neural network modelscompared with other NNS models.Also, it is foundANFIS models with input trapezoidal membership function is best performance from other membership function types to predict fatigue life. It can be stated that neuro-fuzzy models are better models than neural network and conventional methods to predict fatigue life of the maintained alloy

    Optimization of Nano Hydroxyapatite/chitosan Electrophoretic Deposition on 316L Stainless Steel Using Taguchi Design of Experiments

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    The aim of this work is to determine the optimum parameters for deposition of chitosan and mixture of chitosan and hydroxyapatite (HA) layers using electrophoretic deposition.  The layers were on 316L stainless steel substrate. Taguchi approach was utilized to select the optimum parameters for both layers. The parameters used for deposition chitosan are voltage, time and temperature while the parameters used for HA and chitosan are voltage, time, concentration and temperature. Zeta potential tests were employed to measure the solutions stability.  Coating layers were characterized for thickness, porosity and nanoroughness using optical microscopy (OM) and atomic force microscopy (AFM).  The results from Taguchi design of experiments demonstrated that the best conditions for deposition of chitosan and HA layers are  50 V, 5 min, 3 g HA/L and 30°C.    The corresponding thickness, % porosity, nanoroughness and microroughness for optimum conditions were 22 µm, 3.53,  4.48 nm and 3.85 µm respectively

    Effect of Genetic - Environment Interactions for Grain Yield Trait of Some Genotypes of Bread Wheat in Syria, تأثير التفاعل البيئي الوراثي لصفة الغلة الحبية في بعض الطرز الوراثية من القمح الطري في سورية

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    The aim of this investigation was to study the effect of GE-interactions of grain yield of bread wheat using the additive main effects and multiplicative interaction (AMMI) model. Twenty-four genotypes of bread wheat were sown at 13 locations for 3 growing seasons (2006/2007, 2007/2008 and 2008/2009). The results showed that main effects due to E, G, and GE interaction were found to be significant (P6 and Douma48114 Results showed the possibility of improvement the selection of bread wheat genotypes by applying AMMI model and GGE Biplot methodology in multi- Environment trails. هدف البحث لتحليل التفاعل البيئي الوراثي لصفة الغلة للقمح الطري، باستخدام تحليل التأثيرات الأساسية التراكمية والتفاعل المتعدد وتقييم الطرز الوراثية والبيئات (AMMI) زُرعت 24 سلالةً وصنفاً من القمح الطري في 13 موقعاً خلال المواسم الزراعية (2006/2007 – 2007/2008 – و 2008/2009). بينت النتائج أن التأثيرات الأساسية العائدة إلى التأثير البيئي والوراثي والتفاعل البيئي الوراثي كانت معنوية (P\u3c 0.01) وبين تحليل الـ GGE Biplot إمكانية تمييز طرزٍ وراثية ذات تكيف واسع، وأخرى ذات تكيف خاص، وأشار إلى إمكانية إيجاد مواقع ذات قدرة للتمييز بين الطرز الوراثية. فأمكن تحديد مجموعتين تؤثران بشكل متشابه في الطرز، إذ ضمت الأولى مواقع حماة والرقة وحمص والغاب والقامشلي، وضمت الثانية مواقع جلين وكفر صندل ويحمول وإزرع وتل حديا وحران، فيما بقي موقعا دير الزور وتل طير منفردين بتأثيرهما في الطرز، وتم تمييز مواقع جلين والغاب وإزرع كمواقع مثالية لاختبار الطرز على أساس وراثي، وتحديد مجموعة من الطرز الوراثية المتفوقة في الإنتاجية والمستقرة وراثياً، مثل بحوث6 ودوما48114. تفيد النتائج بإمكانية تحسين عملية انتخاب الطرز الوراثية باستخدام طريقتي التحليل GCE Biplot و AMMI تحت ظروف المواقع المختلفة التي تتم فيها تجارب البيئات المتعددة

    Enhanced Recovery After Surgery (ERAS) and the Role of Advanced Hemodynamic Monitoring

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    This study aimed at exploring the Enhanced Recovery After Surgery (ERAS) as a multi-modality, evidence-based approach to improving the quality of patient care after major surgery and to investigate the effectiveness of the implementation of the ERAS on the outcome measures. Therefore, the problem of this study lies in exploring the Enhanced Recovery After Surgery (ERAS) upon the role of advanced hemodynamic monitoring through examining a sample of (220) patients in two Jordanian hospitals (Jordan Hospital and the Specialty Hospital) undergoing major surgery. The study concluded that the patients had witnessed progressive outcome measures in the Improved Post-operative Morbidity Score (POMS), and the Reduced Length of Stay in Hospital, and the Reduced episodes of harm and surgical complications
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