30 research outputs found

    Learning and Thinking Styles Based on Whole Brain Theory in Relation to Sensory-Motor Integration

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    Abstract The study aims to explore learn ing and thinking styles based on Whole Brain Theory; and their relationship with sensory-motor integration. It also explores the correlat ions between variables. Two tests were used to explore the correlations between the two variables (learning and thinking styles based on Whole Brain Theory test and sensory-motor integration test). Tests were admin istered to discover whether the variables differ accord ing to gender and age groups. Validity and reliab ility of the tests were insured. The study was conducted based on a stratified random (cluster) sample of (753) male and female students. The part icipants are (12-16) years old, enro lled in 13 public schools (7 male and 6 female schools) at Irbid first directorate. The study reveals significant correlations between both (Q_D0 F i) and (Q_C1 F ii) wit h sensory-motor integration test due to gender differences in favour of females

    Risk of Obstructive Sleep Apnea in Patients with Type 2 Diabetes Mellitus in Jeddah, Saudi Arabia.

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    Background Obstructive sleep apnea (OSA) is a sleep related breathing disorder defined as repeated episodes of upper airway collapse during sleep. One of the major risk factors of obstructive sleep apnea is obesity. Aim To assess the risk of obstructive sleep apnea among type 2 diabetic patients at National Guard Hospital in Jeddah, Saudi Arabia. Methods The STOP-BANG sleep apnea screening questionnaire was used in this study. The sample size is of 171 participants. A cross-sectional study was performed at National Guard Hospital in Jeddah, Saudi Arabia. A study sample of 171 was included. A STOP-BANG questionnaire formed of eight questions was used to assess the risk of OSA among type 2 diabetic patients. Score of the questionnaire was divided into three groups: Low risk (from 0 to 2 points), intermediate risk (from 3 to 4 points) and high risk (from 5 to 8 points). Results Of all patients with type 2 diabetes mellitus in the study, 9.4 per cent had low risk, 18.7 per cent had intermediate risk and 71.7 per cent had high risk for OSA. There was no significant correlation between the score and last fasting blood sugar and HbA1c’s level, with p-values of 0.554 and 0.335, respectively. There was a significant relationship between the type of treatment and the risk of developing OSA (

    Homo sapiens in Arabia by 85,000 years ago.

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    Understanding the timing and character of the expansion of Homo sapiens out of Africa is critical for inferring the colonization and admixture processes that underpin global population history. It has been argued that dispersal out of Africa had an early phase, particularly ~130-90 thousand years ago (ka), that reached only the East Mediterranean Levant, and a later phase, ~60-50 ka, that extended across the diverse environments of Eurasia to Sahul. However, recent findings from East Asia and Sahul challenge this model. Here we show that H. sapiens was in the Arabian Peninsula before 85 ka. We describe the Al Wusta-1 (AW-1) intermediate phalanx from the site of Al Wusta in the Nefud desert, Saudi Arabia. AW-1 is the oldest directly dated fossil of our species outside Africa and the Levant. The palaeoenvironmental context of Al Wusta demonstrates that H. sapiens using Middle Palaeolithic stone tools dispersed into Arabia during a phase of increased precipitation driven by orbital forcing, in association with a primarily African fauna. A Bayesian model incorporating independent chronometric age estimates indicates a chronology for Al Wusta of ~95-86 ka, which we correlate with a humid episode in the later part of Marine Isotope Stage 5 known from various regional records. Al Wusta shows that early dispersals were more spatially and temporally extensive than previously thought. Early H. sapiens dispersals out of Africa were not limited to winter rainfall-fed Levantine Mediterranean woodlands immediately adjacent to Africa, but extended deep into the semi-arid grasslands of Arabia, facilitated by periods of enhanced monsoonal rainfall

    Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015)

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    Clinical features and outcome of acute myeloid leukemia, a single institution experience in Saudi Arabia

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    Aim: Acute myeloid leukemia (AML) is a type of malignancy that is associated with a malignant alteration of normal hematopoietic stem cells in the bone marrow. The aim of this study was to study the demographics and pathological subtypes of AML, evaluate the response and outcome to different treatment modalities. Methods: This was a retrospective study of adult patients diagnosed with AML at King Abdulaziz Medical City - Riyadh, between 2006 and 2013. Data were retrieved from patients′ files, electronic medical files and laboratory information system. Results: 91 patients were included in the study with a male dominance. M1 was the most common French-American-British subtype with 23 (32%) cases. Patients with intermediate-risk AML were the most common subgroup with 41 (48%) cases followed by high and low-risk subgroups, 29 (33%) and 16 (19%), respectively. 74 patients were treated with intensive chemotherapy, and 17 were on palliative chemotherapy or best supportive treatment. Remission rate was found to be 84% in patients who received induction chemotherapy while 41% of them relapsed. 93% of low-risk patients underwent complete remission (CR) compared to intermediate and high-risk patients (79% and 87% respectively), but it was not statistically significant (P = 0.4). The median follow-up was 19 months, with overall survival (OS) of 46% for all groups. The low-risk patients had the highest OS 57% compared to intermediate and high risk (52% and 36%, respectively), but it was not statistically significant (P = 0.3). 18 patients had been treated with allogeneic stem cell transplant and at a median follow-up of 17 months posttransplant the OS was 72%. Conclusion: This study shows M1 subtype to be the most common of AML in this population. In addition, the CR was better with similar survival rate as compared to other local and internationally published experiences. These results, albeit with its limitations, need to be confirmed in a prospective clinical trial or national disease registry

    Translation and validation of the Functional Assessment of Cancer Therapy-Bone Marrow Transplant (FACT-BMT) version 4 quality of life instrument into Arabic language

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    Abstract Background Functional Assessment of Cancer Therapy-Bone Marrow Transplant (FACT-BMT) has been translated from English into several languages. Currently, there is no validated translation of FACT-BMT in Arabic. Here, we are reporting the first Arabic translation and validation of the FACT-BMT. Methods The study was approved by the Institutional Research Advisory Council. The Arabic translation followed the standard Functional Assessment of Chronic Illness Therapy (FACIT.org) translation methodology (with permission). Arabic FACT-BMT (50- items) was statistically validated. Cronbach’s alpha for internal consistency, Spearman’s rank correlation coefficients method for Inter-scale correlations and Principal Component Analysis for factorial construct validity was used. Results One hundred and eight consecutive relapsed /refractory lymphoma patients who underwent high dose chemotherapy and autologous stem cell transplant were enrolled. There were 68 males (63%) and 40 females (37%) with a median age of 29 years (range 14–62). After Arabic questionnaire pre-testing (Cronbach’s alpha 0.744), the study included 108 patients. Cronbach’s alpha for the entire FACT-BMT indicated an excellent internal consistency (0.90); range (0.67 to 0.91). Cronbach’s alpha for sub-groups of social (0.78), emotional (0.67) and functional wellbeing was (0.88). Cronbach’s alpha for bone marrow transplant (0.81), FACT-General (0.89), and FACT- Trial Outcome Index (TOI); (0.91) also revealed excellent internal consistency. Patients had high scores in all domains of quality of life, indicating that most patients were leading a normal life. This translation of FACT-BMT in Arabic was reviewed and approved for submission by the FACIT.org. Conclusions Our data reports the first translated, validated and approved Arabic version of FACT-BMT. This will help large numbers of Arabic speaking patients undergoing stem cell/bone marrow transplantation, across the globe

    Four successful pregnancies in a patient with Fontan palliation and congenital heart disease: a case report

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    Abstract Background Fontan is a palliative procedure in patients with single ventricle. Single ventricle supports systemic cardiac output and pulmonary blood flow is passively directed to the right pulmonary artery. Women with Fontan palliation are reported to have increased maternal risk during pregnancy. There are few reports of successful pregnancies in such cases. However data on these pregnancies is lacking, we consider this to be the first reported from kingdom of Saudi Arabia. Case presentation We present a 35-year-old woman from the Kingdom of Saudi Arabia who had Fontan surgery and who had four successful pregnancies and multiple miscarriages. She delivered live, low birth weight neonates. Conclusion This report provides an anecdotal evidence that pregnancy can be tolerated in an adequate Fontan patient with successful outcomes

    Amorphous Poly(ethylene terephthalate) Composites with High-Aspect Ratio Aluminium Nano Platelets

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    Previously, we reported that amorphous poly(ethylene terephthalate) (PET) filled with irregular nodular aluminium (Al) particles gave simultaneous increases in tensile modulus, tensile strength, and impact resistance, which is unusual for materials. Here, we investigated the effect of the particle shape and size by using nano-platelet Al. The Al nano-platelets had a thickness higher than graphenes and clays, but lower than mica and talc, and due to their large widths, they had high aspect ratios. Due to the ductility of Al, the platelets maintained the high aspect ratio and did not snap during injection moulding. In addition to avoiding the usual drop in tensile strength and impact, the composites with nano Al platelets gave an unusually high flexural modulus (8 GPa), which was almost double that attained practically with talc, mica, and graphene. This was because of the high tendency of the Al nano platelets to become oriented during moulding. The Al–PET composite would be a more cost-and-performance effective combination for making conductive composites. The Al is a cheaper material than graphene, surface treatment for adhesion (to PET) is unnecessary, and dispersion issues, such as exfoliation and de-aggregation, are not a problem

    Effect of Compatibilizer on the Persistent Luminescence of Polypropylene/Strontium Aluminate Composites

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    There is a demand for long afterglow composites due to their potential applications in nighttime signal boards, sensors, and biomedical areas. In this study, Polypropylene (PP)/strontium aluminate-based composites [SrAl2O4:Eu2+/Dy3+ (SAO1) and Sr4Al14O25: Eu+2, Dy+3 (SAO2)] with maleic anhydride grafted PP compatibilizer (PRIEX) were prepared, and their auto-glowing properties were examined. After UV excitation at 320 nm, the PP/5PRIEX/SAO1 composites showed green emission at 520 nm, and blue emission was observed for PP/5PRIEX/SAO2 around 495 nm. The intensity of phosphorescence emission and phosphorescence decay was found to be proportional to the filler content (SAO1 and SAO2). The FTIR analysis excluded the copolymerization reaction between the SAO1 and SAO2 fillers and the PP matrix during the high-temperature melt mixing process. The SAO1 and SAO2 fillers decreased the overall crystallinity of the composites without affecting the Tm and Tc (melting and crystallization temperature) values. The thermal stability of the composites was slightly improved with the SAO1 and SAO2 fillers, as seen from the TGA curve. Due to the plasticizing effect of the compatibilizer and the agglomeration of the SAO1 and SAO2 fillers, the tensile modulus, tensile strength, and storage modulus of the composites was found to be decreased with an increase in the SAO1 and SAO2 content. The decreasing effect was more pronounced, especially with the bulk-sized SAO2 filler
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