Power quality analysis using frequency domain smooth-windowed Wigner-Ville distribution

Power quality has become a great concern to all electricity consumers. Poor power quality can cause equipment failure, data and economical losses. An automated monitoring system is needed to ensure signal quality, reduce diagnostic time and rectify failures. This paper presents the analysis of power quality signals using frequency domain smooth-windowed Wigner-Ville distribution (FDSWWVD). The power quality signals focused are swell, sag, interruption, harmonic, interharmonic and transient based on IEEE Std. 1159-2009. The TFD represents signal jointly in time-frequency representation (TFR) with good frequency and time resolution. Thus, it is very appropriate to analyze the signals that consist of multi-frequency components and magnitude variations. However, there is no fixed kernel of the TFD can be used to remove cross-terms for all types of signals. A set of performance measures is defined and used to compare the TFRs to identify and verify the TFD that operated at optimal kernel parameters. The result shows that FDSWWVD offers good performance of TFR and appropriate for power quality analysis

Systematic review on role of miRNAs in acute Myocardial Infarction of young adults

Acute myocardial infarction (AMI) is the leading cause of death worldwide. In Malaysia, people are getting AMI at younger age compared to well-developed countries. The role of microRNA (miRNA) in pathogenesis of AMI is not well elucidated and its involvement in young population has not been studied. The systematic review performedusing available electronic databases and also previous reviews. The databases were broad search and began with the generic terms to identify search terms that were relevant. Databases including PubMed, Science Direct and Medline were searched between January 2010 and December 2020 for this systematic review. A total of 97 articles found. Only 1 article showed that the research was done in young AMI population. 13 miRNAs were found to be upregulated and 16 downregulated in young acute coronary syndrome (ACS) patient, which included both ST elevation myocardial infarction (STEMI) and non-ST elevation myocardial infarction (NSTEMI). miRNA 183-5p was significantly upregulated in ACS patients with NSTEMI whereas miRNA 134-5p, miRNA 15a-5p and let 7i-5p weresignificantly downregulated in patients with STEMI compared to healthy control. Plasma miRNA 183-5p, miRNA 134-5p, miRNA 15a-5p and let 7i-5p were dysregulated in STEMI and NSTEMI where they can potentially be used to discriminate the two ACS forms in future study

Systematic review on role of miRNAs In AMI of young adults

Acute myocardial infarction (AMI) is the leading cause of death worldwide. In Malaysia, people are getting AMI at younger age compared to well-developed countries. The role of microRNA (miRNA) in pathogenesis of AMI is not well elucidated and its involvement in young population has not been studied. The systematic review performed using available electronic databases and also previous reviews. The databases were broad search and began with the generic terms to identify search terms that were relevant. Databases including PubMed, Science Direct and Medline were searched between January 2010 and December 2020 for this systematic review. A total of 97 articles found. Only 1 article showed that the research was done in young AMI population. 13 miRNAs were found to be upregulated and 16 downregulated in young acute coronary syndrome (ACS) patient, which included both ST elevation myocardial infarction (STEMI) and non-ST elevation myocardial infarction (NSTEMI). miRNA 183-5p was significantly upregulated in ACS patients with NSTEMI whereas miRNA 134-5p, miRNA 15a-5p and let 7i-5p were significantly downregulated in patients with STEMI compared to healthy control. Plasma miRNA 183-5p, miRNA 134-5p, miRNA 15a-5p and let 7i-5p were dysregulated in STEMI and NSTEMI where they can potentially be used to discriminate the two ACS forms in future study

The role of miRNAs in acute Myocardial Infarction of young adults

Acute myocardial infarction (AMI) is the leading cause of death worldwide. In Malaysia, people are getting AMI at younger age compared to well-developed countries. The role of microRNA (miRNA) in pathogenesis of AMI is not well elucidated and its involvement in young population has not been studied. miRNAs possibly affect the atherogenesis, a precursor for AMI by affecting the genes that regulate endothelial stability, atherosclerotic plaque destabilization, fibrogenesis and heart remodelling post infarction. Understanding the pathogenesis of AMI in this young population is important in providing accurate diagnosis and prompt management of the disease. The aim of our study is to investigate how miRNAs contribute to the pathogenesis of AMI by profiling specific miRNAs that are dysregulated following an AMI in young group and to determine whether these miRNAs lead to the dysregulation of their target mRNA. Blood sample will be taken from the control, young and mature AMI groups and divided into 2 aliquots for the miRNA profiling analysis and mRNA analysis. The gene expressions will be analysed using the Bio-Rad CFX96 software. The significance of miRNA and mRNA expressions will be assessed using appropriate statistical analysis. The discovery of miRNAs involved in the AMI pathogenesis in this study could lead to potential usage as novel biomarkers for detection of early cardiac injury, prognosis and therapeutic intervention

The diet of a roosting population of Asian glossy starling aplonis panayensis in Jelebu, Negeri Sembilan, Malaysia

Communal roosting by urban birds, such as crows, mynas, and starlings, can be a public nuisance due to excessive noise and fouling of the surroundings with droppings. Food availability within proximity to the roosting area is one of the key factors influencing roosting site preference and fidelity. The diets of roosting mynas and crows have been well-studied, yet little is known about the diet of the Asian glossy starling (AGS), Aplonis panayensis. This study focused on assessing the diet of roosting AGS and food resource availability around the roosting area. The AGS diet was assessed through microscopic analysis of stomach contents and droppings. The diet mainly consisted of fruits (76%) with a minor component of animal materials, i.e. ants, snails, and beetle larvae. Intact seeds found in the samples were identified using DNA barcoding. Seven out of the nine plant species detected were new records for the AGS diet. The most common fruit found in the samples was Trema orientalis, which grows extensively along roadsides within foraging areas of AGS. The availability of fruits of different fast-growing pioneer species around the roosting site ensured a continuous supply of food to the birds. Animal materials, which were consumed by chance during foraging, supplemented the fruit in the bird’s diet. Hence, the birds’ preference for the roosting site may have been influenced by the availability of various food resources around it

Role of miRNAs in AMI of young adults

Acute myocardial infarction (AMI) is the leading cause of death worldwide. In Malaysia, people are getting AMI at younger age compared to well-developed countries. The role of microRNA (miRNA) in pathogenesis of AMI is not well elucidated and its involvement in young population has not been studied. miRNAs possibly affect the atherogenesis, a precursor for AMI by affecting the genes that regulate endothelial stability, atherosclerotic plaque destabilization, fibrogenesis and heart remodelling post infarction. Understanding the pathogenesis of AMI in this young population is important in providing accurate diagnosis and prompt management of the disease. The aim of our study is to investigate how miRNAs contribute to the pathogenesis of AMI by profiling specific miRNAs that are dysregulated following an AMI in young group and to determine whether these miRNAs lead to the dysregulation of their target mRNA. Blood sample will be taken from the control, young and mature AMI groups and divided into 2 aliquots for the miRNA profiling analysis and mRNA analysis. The gene expressions will be analysed using the Bio-Rad CFX96 software. The significance of miRNA and mRNA expressions will be assessed using appropriate statistical analysis. The discovery of miRNAs involved in the AMI pathogenesis in this study could lead to potential usage as novel biomarkers for detection of early cardiac injury, prognosis and therapeutic intervention

Power Quality Analysis Using Frequency Domain Smooth - Windowed Wigner - Ville Distribution

Power quality has become a great concern to all electricity consumers. Poor power quality can cause equipment failure, data and economical losses. An automated monitoring system is needed to ensure signal quality, reduce diagnostic time and rectify failures. This paper presents the analysis of power quality signals using frequency domain smooth-windowed Wigner-Ville distribution (FDSWWVD). The power quality signals focused are swell, sag, interruption, harmonic, interharmonic and transient based on IEEE Std. 1159-2009. The TFD represents signal jointly in time-frequency representation (TFR) with good frequency and time resolution. Thus, it is very appropriate to analyze the signals that consist of multi-frequency components and magnitude variations. However, there is no fixed kernel of the TFD can be used to remove cross-terms for all types of signals. A set of performance measures is defined and used to compare the TFRs to identify and verify the TFD that operated at optimal kernel parameters. The result shows that FDSWWVD offers good performance of TFR and appropriate for power quality analysis

Glacie5 Enterprise: Portable Fridge / Nurul Nadhirah Mohd Elias Zulkifli [et al.]

Glacie5 Enterprise is a new company operated and based in Malaysia. The name Glacie is derived and taken from the word Latin which means 'ice', which means that our product is related to cooling and bring coolness to peopl

Morphological characterization and identification of two sesame (Sesamum spp.) ecotypes in Malaysia

Malaysia is endowed with favourable ecologies for sesame (Sesamum spp. L.) cultivation but lack of information on genetic variations among Malaysian sesame populations has been a barrier to select the desirable accessions for commercial cultivation. Present study was done to characterize and identify the level of variations among 30 accessions of two sesame ecotypes collected from Port Dickson and Serdang, by using 39 morphological (19 quantitative and 20 qualitative) traits. Descriptive analysis showed a great amount of similarity for 31 morphological traits, while 8 quantitative traits found to be significantly varied - as for stem circumference, branching, flower number and size, pedicel length, ovary size, capsule number and size. In clustering analysis, the populations of both locations tended to cluster in a main group according to their qualitative traits similarity, but separated in two groups based on quantitative traits, indicating that quantitative traits are the dominant trait for separations of accessions. However, the dendogram developed in this study revealed four distinct clusters in which most of the accessions between two ecotypes were closely related with a similarity co-efficient ranged from 0.744 to 0.487. Finally, all the accessions were to be considered as Sesamum radiatum due to the matching of capsule and seed characteristics with the taxonomic key developed for the identification of specific sesame species. The study therefore suggests that morphological variability observed in both populations is mainly attributed to differential habitat and soil nutrient conditions rather than genotypic diversity

The identification of microRNAS Pathogenic pathway in acute Myocardial Infarction of young adults

Acute myocardial infarction (AMI) is a severe form of coronary heart disease where Malaysians are getting AMI at younger age compared to well-developed countries. MicroRNAs (miRNAs) are implicated in AMI pathogenesis, but no study looked at their profiling or involvement in young population. The present study aims to profile the miRNAs expressions in healthy controls (aged 18 to 45 years), young AMI (YAMI) (aged ≤ 45 years), and mature AMI (MAMI) (aged ≥ 46 years) patients with matching criteria, and to determine the effect of the dysregulated miRNAs on the target mRNAs as well as the pathways involve in the pathogenesis of AMI. This study was conducted on twenty Malay males for each group in Kuantan, Pahang. Total RNA was extracted from plasma and the miRNA expression profiling was carried out on the BGISEQ500 SE50 sequencing platform with BGI sequencing libraries. The sequence data were analyzed using Gene Ontology (GO) to determine the role of the differentially expressed genes, followed by the Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis for identification of the biological pathways in YAMI against MAMI. The top six dysregulated miRNAs identified during sequencing were validated using quantitative reverse-transcription polymerase chain reaction (qRT-PCR) between the groups. ANOVA and unpaired T-test were used to analyze the differences of miRNAs and gene expression between the three groups. This study revealed that majority AMI patients were smokers, where YAMI patients had higher BMI, SBP, DBP and TG while MAMI patients had higher FBG than the rest of the group. A total of 1599 miRNAs were differentially expressed in AMI (YAMI and MAMI) patients compared to healthy controls, where 1288 were upregulated and 311 were downregulated (FDR ≤ 0.001). However, when YAMI patients were compared to MAMI patients, 1497 miRNAs were found to be dysregulated, of which 1090 miRNAs were upregulated, and 407 miRNAs were downregulated (FDR ≤ 0.001). The top ten upregulated miRNAs were miR-552, miR-4446-3p, miR-432-5p, miR-548j-5p, miR-219, miR-982, miR-181a-2-3p, miR-654-5p, miR-58 and miR-548k; while the top ten downregulated were miR-16-5p, miR-1064, miR-431-5p, miR-790 miR-1177, miR-201, miR-105, miR-518, miR-419 and miR-1103. This study also discovered ten novel miRNAs: miR-4446-3p, miR-982, miR-58, miR-548k, miR-1064, miR-790, miR-1177, miR-201, miR-419, and miR-1103. The validation of the top six dysregulated miRNAs between YAMI and MAMI patients revealed the upregulation of miR-423-5p by 2.08-fold (p = 0.040) and downregulation of miR-431-5p by 33.90-fold (p = 0.034), and miR-378a-5p by 34.61-fold (p = 0.040). For these 1497 differentially expressed miRNAs, 34,195 target genes were predicted by GO analysis. The functional analysis demonstrated 11,199 GO terms found to be involved in biological processes, 12,012 in cellular components, and 10,984 in molecular functions were significantly enriched (p < 0.05). The target genes that were mapped to the signal transduction pathway in KEGG revealed 346 classes were enriched. In conclusion, miRNAs are differentially expressed between young and mature AMI, ten of which are novel. Three biological pathways, ascorbate and aldarate metabolism, collecting duct acid secretion and glycosaminoglycans biosynthesis – heparin sulfate/heparin were identified but their involvements in the regulatory mechanisms on gene expression in Young AMI need further evaluation