Printing of cotton fabrics using microwave irradiation

Irradiation Microwave was used in fixation of pigment prints on cotton fabrics with a colour strength parameters comparable with the previous research obtained in case of thermo-fixation procedures. However printing pastes was introduced to the fabric via screen printing methods. The printed fabrics was subjected to irradiation microwave for different periods of time at microwave power. Results of both covered and uncovered ranges from 3.8 to 10.70 and 1.66 to 8.20.Also the effect of irradiation microwave on printed cotton fabrics with yellow pigment for 6 min, for both covered and uncovered ranges from 3.50 to 15.52 and 5.20 to 16.80, likewise fastness properties of the cotton fabrics printed with yellow pigment fixed either by optimum conditions for irradiation microwave for both washing and rubbing which ranges from 4/5 for colour change(cc) and for colour staining(cs) which is 4. In order to compare the initial result, another samples of cotton fabrics were printed with the same paste, dried and subjected to fixation procedure. The colour strength of the printed cotton fabrics fixed through irradiation microwave was found to be time and microwave power dependent. Results of this investigation clarified also that, regardless of the time of microwave, covering the pigment printed cotton fabric samples with covered and uncovered sample. Furthermore, the influence of reduction of the particle size of pigment yellow colour to the nano-scale on the colour strength and overall fastness properties of cotton fabrics printed and fixed using irradiation microwave was determined

The Challenges of the Fight Against Insurgency in Northeastern Nigeria

The Boko Haram insurgency in Northeastern Nigeria has been one of the most devastating phenomena in the country claiming thousands of lives and properties worth billions of Naira in the process. All the governmental efforts put in place so far failed to curb the menace as the threat of insurgency continues in some parts of Northeastern Nigeria. This work examined the major challenges that are responsible for the continuation of insurgency despite divergent measures taken by the government to address the problem. The research used both primary and secondary sources of data. The primary source is the in-depth interview conducted with some selected informants who are related with security issues involving security personnel in the Northeast, policy-makers, analysts, some repented insurgents and media men. The secondary source is the use of the existing documents such as books, reports, news and internet sources. The data obtained was discussed and analysed using thematic analytical interpretations to arrive at findings. The research discovered that, the major reasons or challenges that made insurgency defiant of all solutions in Northeastern Nigeria consists of corruption, conspiracy, inappropriate approach, lack of proper intelligence, hostility from the host communities, nature of Nigerian borders, politicisation of security issues, religious dogmatism and lack of cooperation among the security personnel. Therefore, for an effective approach towards addressing the problem of insurgency in Northeastern Nigeria, the paper recommends that a multi-dimensional approach is required such as religious censorship, intelligence, cooperation, prudence and good governance. Â

Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial

Background Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients. We aimed to assess the effects of early administration of tranexamic acid on death, hysterectomy, and other relevant outcomes in women with post-partum haemorrhage. Methods In this randomised, double-blind, placebo-controlled trial, we recruited women aged 16 years and older with a clinical diagnosis of post-partum haemorrhage after a vaginal birth or caesarean section from 193 hospitals in 21 countries. We randomly assigned women to receive either 1 g intravenous tranexamic acid or matching placebo in addition to usual care. If bleeding continued after 30 min, or stopped and restarted within 24 h of the first dose, a second dose of 1 g of tranexamic acid or placebo could be given. Patients were assigned by selection of a numbered treatment pack from a box containing eight numbered packs that were identical apart from the pack number. Participants, care givers, and those assessing outcomes were masked to allocation. We originally planned to enrol 15 000 women with a composite primary endpoint of death from all-causes or hysterectomy within 42 days of giving birth. However, during the trial it became apparent that the decision to conduct a hysterectomy was often made at the same time as randomisation. Although tranexamic acid could influence the risk of death in these cases, it could not affect the risk of hysterectomy. We therefore increased the sample size from 15 000 to 20 000 women in order to estimate the effect of tranexamic acid on the risk of death from post-partum haemorrhage. All analyses were done on an intention-to-treat basis. This trial is registered with ISRCTN76912190 (Dec 8, 2008); ClinicalTrials.gov, number NCT00872469; and PACTR201007000192283. Findings Between March, 2010, and April, 2016, 20 060 women were enrolled and randomly assigned to receive tranexamic acid (n=10 051) or placebo (n=10 009), of whom 10 036 and 9985, respectively, were included in the analysis. Death due to bleeding was significantly reduced in women given tranexamic acid (155 [1·5%] of 10 036 patients vs 191 [1·9%] of 9985 in the placebo group, risk ratio [RR] 0·81, 95% CI 0·65–1·00; p=0·045), especially in women given treatment within 3 h of giving birth (89 [1·2%] in the tranexamic acid group vs 127 [1·7%] in the placebo group, RR 0·69, 95% CI 0·52–0·91; p=0·008). All other causes of death did not differ significantly by group. Hysterectomy was not reduced with tranexamic acid (358 [3·6%] patients in the tranexamic acid group vs 351 [3·5%] in the placebo group, RR 1·02, 95% CI 0·88–1·07; p=0·84). The composite primary endpoint of death from all causes or hysterectomy was not reduced with tranexamic acid (534 [5·3%] deaths or hysterectomies in the tranexamic acid group vs 546 [5·5%] in the placebo group, RR 0·97, 95% CI 0·87-1·09; p=0·65). Adverse events (including thromboembolic events) did not differ significantly in the tranexamic acid versus placebo group. Interpretation Tranexamic acid reduces death due to bleeding in women with post-partum haemorrhage with no adverse effects. When used as a treatment for postpartum haemorrhage, tranexamic acid should be given as soon as possible after bleeding onset. Funding London School of Hygiene & Tropical Medicine, Pfizer, UK Department of Health, Wellcome Trust, and Bill & Melinda Gates Foundation

First report of camel contagious ecthyma in Nigeria

Camel contagious ecthyma (CCE) is a viral disease of camelids that is caused by a Parapoxvirus (PPV) which is a DNA virus of the viral family: Poxviridae. Diseases affecting camels in Nigeria are scarcely reported. CCE or the laboratory detection of camel PPV (CPPV) has not been reported in Nigeria. This study investigated and described the clinical presentation of CCE and molecular detection of CPPV in Nigeria. Suspected cases of CCE were reported in a farm, live animal market and abattoir, in three different states (Bauchi, Plateau and Zamfara) in Northern Nigeria. Skin scabs, lungs, liver and intestine samples were collected. Polymerase chain reaction (PCR) was carried out using the primers which targets the RPO30 gene fragment of the genus PPV. The clinical signs observed from the suspected cases of CCE were proliferative skin lesions, papules, scabs on the lips and nares. CPPV was detected in 80.0% (4/5) of the samples collected by PCR. CCE was diagnosed based on clinical signs and PCR results. This is the first report of CCE in Nigeria. Further studies should be carried out to genetically characterize the CPPV circulating in Nigeria

Beta-Lactam Resistance Profile of E. Coli Isolated from Urinary Tract Infection Patients in Selected Hospitals within Gusau Metropolis

The emergence of antibiotic resistance, particularly beta-lactam resistance, poses a significant challenge in the management of urinary tract infections (UTIs) caused by Escherichia coli (E. coli). This study aimed to investigate the beta-lactam resistance profile of E. coli isolated from UTI patients in selected hospitals within the Gusau metropolis. A total of 92 urine samples were collected from UTI patients attending selected hospitals in Gusau metropolis. Isolation and identification of E. coli were conducted using standard microbiological techniques. Antibiotic susceptibility testing was performed using the disc diffusion method according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Furthermore, phenotypic confirmation of beta-lactam resistance was carried out using double disc synergy testing (DDST).  Out of 92 urine samples obtained from patients with UTIs, E. coli was identified in 19 samples (20.7%), out of the 19 E. coli isolates, ESBL production was detected in 9 (47.36%) based on the results of the DDST, and among the E. coli isolates tested, 12 (63.16%) exhibited resistance to beta-lactam (Ceftriaxone), while 5 (26.31%) showed intermediate susceptibility, and 2 (10.53%) were susceptible to this antibiotic. Results revealed a concerning prevalence of beta-lactam resistance among E. coli isolates, highlighting the urgent need for effective antimicrobial stewardship and infection control measures in the region