Diacylglycerol oil for the metabolic syndrome

Excess adiposity has been shown to play a crucial role in the development of the metabolic syndrome. The elevated fasting and postprandial triglyceride-rich lipoprotein levels is the central lipid abnormality observed in the metabolic syndrome. Recent studies have indicated that diacylglycerol (DAG) is effective for fasting and postprandial hyperlipidemia and preventing excess adiposity by increasing postprandial energy expenditure. We will here discuss the mechanisms of DAG-mediated improvements in hyperlipidemia and in postprandial energy expenditure, and effects of DAG oil on lipid/glucose metabolism and on body fat. Further, the therapeutic application of DAG for the metabolic syndrome will be considered

Kinetics of oxidation of metals in the air at room temperature using EDX

The kinetics of oxidation of Zn, Cu, Ni and C. steel were studied using the surface techniques, SEM, EDX and XRD, and electrochemical impedance spectroscopy (EIS) technique. EDX results showed that the variation of weight percent oxygen (Wt% O) on the surface of the four metals with the exposure time gave the same behavior, there is an increase of Wt% O with increasing the exposure time until about 2 h followed by a plateau, then the Wt% O increases again with increasing the time of exposure than 4 h. Fitting the experimental data of the four metals to the kinetic laws of oxidation indicated that the logarithmic law was fitted in short exposure (0.5 – 4 h), however, the parabolic law was fitted in long exposure (6 – 10 h). The values of each logarithmic rate constant (kl) and parabolic rate constant (kp)for the four metals were calculated. The kinetic of oxidation of the metals under study with exposure time is confirmed utilizing XRD technique. The protective action of the air-formed oxide films was investigated by EIS technique. The electrochemical impedance spectroscopy results confirmed the EDX results

Early Recognition of Persistent Acute Kidney Injury

International audienc

Clinical characteristics, risk factors and outcome of severe Norovirus infection in kidney transplant patients: a case-control study

International audienceBackground: Human Norovirus (HuNoV) has recently been identified as a major cause of diarrhea among kidney transplant recipients (KTR). Data regarding risk factors associated with the occurrence of HuNoV infection, and its long-term impact on kidney function are lacking. Methods: We conducted a retrospective case-control study including all KTR with a diagnosis of HuNoV diarrhea. Each case was matched to a single control according to age and date of transplantation, randomly selected among our KTR cohort and who did not develop HuNoV infection. Risk factors associated with HuNoV infection were identified using conditional logistic regression, and survival was estimated using Kaplan-Meier estimator. Results: From January 2012 to April 2018, 72 cases of NoV diarrhea were identified among 985 new KT, leading to a prevalence of HuNoV infection of 7.3%. Median time between kidney transplantation and diagnosis was 46.5 months (Inter Quartile Range [IQR]:17.8-81.5), and the median duration of symptoms 40 days (IQR: 15-66.2). Following diagnosis, 93% of the cases had a reduction of immunosuppression. During follow-up, de novo Donor Specific Antibody (DSA) were observed in 8 (9%) cases but none of the controls (p = 0.01). Acute rejection episodes were significantly more frequent among cases (13.8% versus 4.2% in controls; p = 0,03), but there was no difference in serum creatinine level at last follow-up between the two groups (p = 0.08). Pre-transplant diabetes and lymphopenia below 1000/mm 3 were identified as risks factors for HuNoV infection in multivariate analysis. Conclusion: HuNoV infection is a late-onset and prolonged infection among KTR. The current management, based on the reduction of immunosuppressive treatment, is responsible for the appearance of de novo DSA and an increase in acute rejection episodes

Corrosion protection and antifouling properties of varnish-coated steel containing natural additive

The corrosion protection and antifouling properties of varnish-coated steel panels containing different amounts of cannabis extracts were investigated using electrochemical impedance spectroscopy (EIS), salt spray and immersion tests in 0.5 M NaCl solution and subjected to a field test in seawater. Analysis of the experimental data showed that the presence of cannabis extract resisted the deterioration (peeling off) tendency of the varnish-coated steel panels exposed to aggressive environments. Visual inspection showed that the cannabis extract also provided good antifouling properties

Some Microbial Causes of Mortality in Rabbit in Northwest of Delta, Egypt

This study aimed to investigate pathogenic microbial causes of mortalities in twenty rabbit flocks located in 4 governorates in Northwest of Delta Egypt during a period from 2019 to 2022.The mortality rate was varied from 10 to 90 % in either sex of different breeds and ages (15 day-18 month). Ten flocks (50%) were positive for Rabbit hemorrhagic disease virus (RHDV) by HA and RT-PCR. Phylogenetic analysis of the VP60 gene indicated one sample (MW455128) was classic RHDV and eight strains (MW455120 - MW455127) were variant RHDV2.Enteropathogenic Escherichia coli (EPEC) was the predominant isolated bacteria (60%), belonging to various serotypes (poly 1, O26 K60, poly 2, O55 K59, poly 2, O126 K71, poly 1, O111, and poly 3, O114), followed by K. pneumoniae (35%), which was determined to be virulent by PCR detection of the uge gene (80%) and rmpA (40%), while the kfu gene was absent. Staph. aureus and Pasteurella multocida represented (30%) for each, while pseudomonas aeruginosa (20%) and Salmonella was negative. Pathologically, apoptosis was the most prominent lesion observed in liver, kidney, intestine, spleen, lung and heart, also there were severe enteritis, abscess in lung, liver and kidney and suppurative bronchopneumonia. By immunohistochemistry the RHDV antigen was detected in hepatic, splenic, renal, pulmonary, and cardiac tissues. The findings of this investigation highpoints on the significance of RHDVs (classic G3-G5 and variant RHDV2 which become more predominant), EPEC, K. pneumonia, S. aureus, P. multocida and p. aeruginosa  as rabbit pathogens causing mortalities in studied Egyptian provinces. So that, these results are important in any effort to control rabbit pathogens in Egypt