Flame Atomic Emission and Colorimetric Methods for the Determination of Cephalexin Monohydrate in Pharmaceutical Preparations

We propose two simple, rapid, and convenient spectrophotometric methods which are described for the determination of cephalexin in bulk and its pharmaceutical preparations. They are based on the measurement of the flame atomic emission of potassium ion (in the first method) and colorimetric determination of the green colored solution at 610 nm formed after the reaction of cephalexin with potassium permanganate as an oxidant agent (in the second method) in basic medium. The working conditions of the methods are investigated and optimized. Beer's law plot shows a good correlation in the concentration range of 5-40?g ml-1. The detection limits are 2.573,2.814 ?g ml-1 for the flame emission photometric method and 1.844,2.016 ?g ml-1 for colorimetric methods for capsules and suspensions respectively.The methods are successfully applied to the determination of cephalexin in capsules and suspensions, and the obtained results are in good agreement with the label claim. No interference is observed from the commonly encountered additives and excipients

INTELLIGENT SURVEILLANCE SYSTEM FOR FIRE DETECTION USING YOLOV8

This study describes a lightweight deep learning model trained on a self-made image dataset taken inside farms and open areas of the Holy Shrine of Al-Hussainiya in the City of Karbala, Iraq. This dataset includes fire and smoke images taken using a Samsung A52S camera in different weather conditions. The overall goal is to create a fire detection system model that can successfully replace the existing physical sensor-based fire detectors and lessen the issues that come with such fire detectors, including false and delayed triggering. Another goal is to control fires on farms or open areas and prevent crop damage as much as possible. Previous studies were reviewed. Moreover, the architecture of the You Only Look Once version 8 (YOLOv8) model was briefly explained, and the results it achieved were compared with those achieved by previous versions. Then, the proposed system was trained and evaluated with the YOLOv8 large model. Results showed that the proposed system outperformed the rest of the current systems in mAP, which reached 98.5%

Anti-inflammatory and Antioxidant Activity Screening for New Steroidal Schiff Bases

In the present work, two aldehyde derivatives were synthesized one from cholesterol and one from ergosterol and further condensed with three different primary amines (2-amino 6-fluoro benzathiazole, thiosemicarbazide, carbohydrazide) to yield the corresponding Schiff’s bases. The synthesized compounds were verified using spectral analysis, including IR, 1H-NMR, and GC Mass, and were tested for antioxidant and anti-inflammatory properties. From the synthetic materials, three to four compounds showed significant anti-inflammatory and antioxidant activities.

Efficient Up-Conversion in CsPbBr3 Nanocrystals via Phonon-Driven Exciton-Polaron Formation

Lead halide perovskite nanocrystals demonstrate efficient up-conversion, although the precise mechanism remains a subject of active research. This study utilizes steady-state and time-resolved spectroscopy methods to unravel the mechanism driving the up-conversion process in CsPbBr3 nanocrystals. Employing above- and below-gap photoluminescence measurements, we extract a distinct phonon mode with an energy of ~7 meV and identify the Pb-Br-Pb bending mode as the phonon involved in the up-conversion process. This result was corroborated by Raman spectroscopy. We confirm an up-conversion efficiency reaching up to 75%. Transient absorption measurements under conditions of sub-gap excitation also unexpectedly reveal coherent phonons for the subset of nanocrystals undergoing up-conversion. This coherence implies that the up-conversion and subsequent relaxation is accompanied by a synchronized and phased lattice motion. This study reveals that efficient up-conversion in CsPbBr3 nanocrystals is powered by a unique interplay between the soft lattice structure, phonons, and excited states dynamics.Comment: Main text has 6 figures, supporting information has 7 figures. total number of pages 3

A three-way decision-making technique based on Pythagorean double hierarchy linguistic term sets for selecting logistic service provider and sustainable transportation investments

Finding the best transportation project and logistic service provider is one for the most important aspects of the development of a country. This task becomes more complicated from time to time as different criteria are involved. Hence, this paper proposes an approach to the linguistic three-way decision-making (TWDs) problem for selecting sustainable transportation investments and logistic service providers with unknown criteria and expert weight information. To this end, we first propose a new tool, the Pythagorean double hierarchy linguistic term sets (PyDHLTSs), which is a combination of first hierarchy linguistic term sets and second hierarchy linguistic term sets which can describe uncertainty and fuzziness more flexibly in decision-making (DM) problems. In addition, we propose some aggregation operators and basic operational laws for PyDHLTSs. A new decision-making technique for PyDHLTSs based on decision-theoretic rough sets (DTRSs) is proposed in the three-way decisions. Next, the conditional probability is computed using grey relational analysis in a PyDHLTSs environment, which improves decision-making. The loss function is computed by using the proposed aggregation operator, and the decision's results are determined by the minimum-loss principle. Finally, a real-world case study of a transportation project and logistic service provider is considered to demonstrate the efficiency of the proposed methods

Brugada syndrome unmasked by fever: a comprehensive review of literature

Background: The Brugada pattern is identified on the EKG by a coved ST-segment elevation accompanied by a negative T wave in the early precordial leads in the absence of a cardiac structural abnormality. Brugada pattern and Brugada syndrome should be differentiated, as the latter is associated with an increased risk of sudden cardiac death. Methods: The literature was searched using multiple databases to identify all the articles on Brugada pattern. Data were screened and analyzed by independent authors. Results: Sixty articles, comprising 71 patients, were included in the study. The mean age of patients was 42.6 years, with a higher prevalence of Brugada pattern in men (83%) than women (17%). The most frequent findings associated with Brugada pattern was fever (83%). Other less common presentations included cough (21%), sore throat (10%), syncope (18%), abdominal pain (8%), and chest pain (7%). Comorbidities included pneumonia (30%), upper respiratory tract infections (14%) and smoking (14%). Among treatment modalities, 39% of patients had ICD placement performed, 44% received antibiotics, while 14% had supportive care. Adenosine was given to 3% of patients, while other antiarrhythmics like milrinone, amiodarone, sotalol, procainamide, flecainide, and nitroglycerin were given to 1% of patients. Most patients with Brugada syndrome had a satisfactory outcome, with only 4% mortality rate(WHAT ABOUT THE OTHER 11%?). Out of the 71 patients, 3% had persistent Brugada patterns, while 86% of patients recovered completely. There was no significant effect of ICD on mortality or Brugada pattern resolution (p 0.37). Conclusion: Our study shows that fever is the main reason for unmasking the Brugada pattern in patients with this channelopath

Chromium removal from aqueous solution using bimetallic Bi\u3csup\u3e0\u3c/sup\u3e/Cu\u3csup\u3e0\u3c/sup\u3e-based nanocomposite biochar

Chromium (Cr), due to its greater contamination in aquifers and distinct eco-toxic impacts, is of greater environmental concern. This study aimed to synthesize nanocomposites of almond shells biochar (BC) with zerovalent bismuth and/or copper (Bi0/BC, Cu0/BC, and Bi0–Cu0/BC) for the removal of Cr from aqueous solution. The synthesized nanocomposites were investigated using various characterization techniques such as XRD, FTIR spectroscopy, SEM, and EDX. The Cr removal potential by the nanocomposites was explored under different Cr concentrations (25–100 mg/L), adsorbent doses (0.5–2.0 g/L), solution pH (2–8), and contact time (10–160 min). The above-mentioned advanced techniques verified successful formation of Bi0/Cu0 and their composite with BC. The synthesized nanocomposites were highly effective in the removal of Cr. The Bi0–Cu0/BC nano-biocomposites showed higher Cr removal efficiency (92%) compared to Cu0/BC (85%), Bi0/BC (76%), and BC (67%). The prepared nanocomposites led to effective Cr removal at lower Cr concentrations (25 mg/L) and acidic pH (4.0). The Cr solubility changes with pH, resulting in different degrees of Cr removal by Bi0–Cu0/BC, with Cr(VI) being more soluble and easier to adsorb at low pH levels and Cr(III) being less soluble and more difficult to adsorb at high pH levels. The experimental Cr adsorption well fitted with the Freundlich adsorption isotherm model (R 2 \u3e 0.99) and pseudo-second-order kinetic model. Among the prepared nanocomposites, the Bi0–Cu0/BC showed greater stability and reusability. It was established that the as-synthesized Bi0–Cu0/BC nano-biocomposite showed excellent adsorption potential for practical Cr removal from contaminated water

The Effect of Mycotoxins on Human Health

The aim of the current study is, what are mycotoxins, what are the risks of mycotoxins on human health, where are mycotoxins found in nature, and what are the health effects of mycotoxins on humans. the questionnaire was created electronically via the Google Drive program, and then it was distributed via mobile phone on the social networking program (WhatsApp)? Using e-mail for all participants to respond to the questionnaire. 650 questionnaires were distributed to all mobile groups, and 600 questionnaires were received on the researcher’s e-mail. (The target group is residents of the holy city of Mecca, aged 25-55 years)

Integral effects of brassinosteroids and timber waste biochar enhances the drought tolerance capacity of wheat plant

Drought stress is among the major threats that affect negatively crop productivity in arid and semi-arid regions. Probably, application of some additives such as biochar and/or brassinosteroids could mitigate this stress; however, the mechanism beyond the interaction of these two applications is not well inspected. Accordingly, a greenhouse experiment was conducted on wheat (a strategic crop) grown under deficit irrigation levels (factor A) i.e., 35% of the water holding capacity (WHC) versus 75% of WHC for 35 days while considering the following additives, i.e., (1) biochar [BC, factor B, 0, 2%] and (2) the foliar application of 24-epibrassinolide [BR, factor C, 0 (control treatment, C), 1 (BR1) or 3 (BR2) mu mol)]. All treatments were replicated trice and the obtained results were statistically analyzed via the analyses of variance. Also, heat-map conceits between measured variables were calculated using the Python software. Key results indicate that drought stress led to significant reductions in all studied vegetative growth parameters (root and shoot biomasses) and photosynthetic pigments (chlorophyll a, b and total contents) while raised the levels of oxidative stress indicators. However, with the application of BC and/or BR, significance increases occurred in the growth attributes of wheat plants, its photosynthetic pigments, especially the combined additions. They also upraised the levels of enzymatic and non-enzymatic antioxidants while decreased stress indicators. Furthermore, they increased calcium (Ca), phosphorus (P) and potassium (K) content within plants. It can therefore be deduced that the integral application of BR and BC is essential to mitigate drought stress in plants.Peer reviewe