The cardiomyopathy of Friedreich's ataxia common in a family: A case report

Introduction and importance: Friedreich's Ataxia is an autosomal recessive disease and is usually associated with arterial dysfunction, muscle weakness, spasm in the lower extremities, scoliosis, bladder dysfunction, lack of reflexes in the lower extremities, and imbalance. Approximately 2.3 people have cardiomyopathy. In this article, we have reviewed a case of Friedreich's Ataxia with hypertrophic cardiomyopathy. Case presentation: A 19-year-old woman with Friedreich's Ataxia has been protesting since she was 11 years old and complained of chest pains, dyspnea, and heart palpitations without a medical history. In ECG, Asymmetrical invert T wave diffuse, diffuse ST-segment depression, and left ventricular hypertrophy were observed. In echocardiography, the left ventricle was reported as hyperimmobile with increased EF (70�75). Clinical discussion: In the present study, a patient with Friedrich Ataxia was diagnosed with chest pain, dyspnea, and palpitations without any medical history, and was discharged from the hospital after treatment. In the patients introduced and our patient, there was significant fibro-myocardial hypertrophy, in which the ventricular septal hypertrophy was marked by hypertrophic cardiomyopathy. Conclusion: Because early diagnosis of the disease is difficult, clinical signs and the patient's current profile at the time of referral will be very helpful. © 202

The effect of inhalation aromatherapy of geranium on pain and physiological indices after appendectomy: A double-blind randomized clinical trial

Introduction: The aim of the present study was to evaluate the effect of inhalation aromatherapy with sweet-scented geranium essential oil on pain and physiological indices after appendectomy. Methods: This double-blind clinical trial was performed on 120 patients undergoing appendectomy. Aromatherapy was performed with 1 sweet-scented geranium and sweet almond oil in the experimental placebo groups, respectively. Physiological symptoms were recorded before induction of anesthesia, before surgery, 30 min and 4 h after surgery. The control group received no intervention and only pain intensity and physiological indices were recorded in the mentioned stages. The placebo group underwent sweet almond essential oil aromatherapy. Data collection tools included demographic information form, physiological index checklist, and visual pain scale. Results: Results of 7 measurements showed significant differences between the experimental and placebo groups as well as the experimental and control groups in terms of mean heart rate, systolic and diastolic blood pressure, blood oxygen percentage, and pain (P < 0.001). Conclusion: Results of the present study showed that the effect of inhalation aromatherapy with sweet-scented geranium essential oil after appendectomy reduces pain and physiological indices. Therefore, the above aromatherapy can be used as a complementary treatment along with other treatments. © 2020 The Author

Prevalence of gestational diabetes mellitus in Eastern Mediterranean region: a systematic review and meta-analysis

Purpose: Gestational diabetes mellitus (GDM) is one of the costly challenges in the health field. Despite the individual studies in the Eastern Mediterranean, there is no comprehensive study in this regard. The aim of this study was to determine the prevalence of GDM in the Eastern Mediterranean region. Methods: In this meta-analysis and systematic review, three international databases (PubMed, Web of science and Scopus) were searched from inception until 30 December 2018. The Hui tool was used to assess the quality of the included studies. Results: Thirty-three studies performed on 887166 participants were included in the meta-analysis. Based on the results of random effect method, the overall prevalence of GDM was 11.7%. Between six country with have three or more study, pooled prevalence for Saudi Arabi it was 3.6 times more than Israel (17.6 vs. 4.9%), and for Pakistan, Qatar, Bahrain and Iran were 15.3%, 14.7%, 12.2%, and 8.6%, respectively. Conclusion: Despite the high diversity of methods, the results of the present study indicate a high prevalence of GDM in the Eastern Mediterranean region, indicating more policymakers’ interest in timely screening and proper management

Tensorized multi-view subspace representation learning

Self-representation based subspace learning has shown its effectiveness in many applications. In this paper, we promote the traditional subspace representation learning by simultaneously taking advantages of multiple views and prior constraint. Accordingly, we establish a novel algorithm termed as Tensorized Multi-view Subspace Representation Learning. To exploit different views, the subspace representation matrices of different views are regarded as a low-rank tensor, which effectively models the high-order correlations of multi-view data. To incorporate prior information, a constraint matrix is devised to guide the subspace representation learning within a unified framework. The subspace representation tensor equipped with a low-rank constraint models elegantly the complementary information among different views, reduces redundancy of subspace representations, and then improves the accuracy of subsequent tasks. We formulate the model with a tensor nuclear norm minimization problem constrained with ℓ2,1-norm and linear equalities. The minimization problem is efficiently solved by using an Augmented Lagrangian Alternating Direction Minimization method. Extensive experimental results on diverse multi-view datasets demonstrate the effectiveness of our algorithm