Update of the Swiss source model for road traffic noise

In Switzerland, the calculation method of road traffic noise is specified in the Ordonnance sur la protection contre le bruit (OPB) (Noise Protection Ordonnance (NPO)). This method is mainly based on observations that were realized in the 80s, and that are not satisfactory many situations anymore. Since the 80s, the traffic volumes have increased, new developments in car and road technologies have occurred, behaviors of users have changed. All these parame-ters contribute to lower reliability of the initial method. Even if the model is still correct in some case such as for fluid traffic, the obtained levels in different types of traffic are hardly reliable. In collaboration with the Swiss Federal Office for the Environment (FOEN), a re-search program has been setup to update the method according to those observations. The ob-jective was to give new guidelines to evaluate emission levels of roads. An important collect of data from cantons and others acoustics partners has been performed as well as measure-ments in real traffic conditions. That made it possible to gather about 7500 points of mea-surement through all Switzerland for several types of road and traffic conditions

Relapse according to antipsychotic treatment in schizophrenic patients: a propensity-adjusted analysis

<p>Abstract</p> <p>Objective</p> <p>To compare the rate of relapse as a function of antipsychotic treatment (monotherapy vs. polypharmacy) in schizophrenic patients over a 2-year period.</p> <p>Methods</p> <p>Using data from a multicenter cohort study conducted in France, we performed a propensity-adjusted analysis to examine the association between the rate of relapse over a 2-year period and antipsychotic treatment (monotherapy vs. polypharmacy).</p> <p>Results</p> <p>Our sample consisted in 183 patients; 50 patients (27.3%) had at least one period of relapse and 133 had no relapse (72.7%). Thirty-eight (37.7) percent of the patients received polypharmacy. The most severely ill patients were given polypharmacy: the age at onset of illness was lower in the polypharmacy group (p = 0.03). Patients that received polypharmacy also presented a higher general psychopathology PANSS subscore (p = 0.04) but no statistically significant difference was found in the PANSS total score or the PANSS positive or negative subscales. These patients were more likely to be given prescriptions for sedative drugs (p < 0.01) and antidepressant medications (p = 0.03). Relapse was found in 23.7% of patients given monotherapy and 33.3% given polypharmacy (p = 0.16). After stratification according to quintiles of the propensity score, which eliminated all significant differences for baseline characteristics, antipsychotic polypharmacy was not statistically associated with an increase of relapse: HR = 1.686 (0.812; 2.505).</p> <p>Conclusion</p> <p>After propensity score adjustment, antipsychotic polypharmacy is not statistically associated to an increase of relapse. Future randomised studies are needed to assess the impact of antipsychotic polypharmacy in schizophrenia.</p

Laser à milieu amplicateur céramique Yb:CaF2 (poster)

International audienceNous présentons le premier laser pompé par diode à amplificateur céramique d'Yb:CaF 2 élaborées par un procédé de synthèse simple et écologique. Nous obtenons une puissance laser de 1,6 W pour une puissance absorbée de 4 W. Les résultats sont comparables à ceux obtenus avec un monocristal d'Yb:CaF 2 de taux de dopage analogue et ouvrent ainsi des perspectives intéressantes pour ces nouvelles céramiques optiques dans le cadre des lasers de puissance pompés par diode

Laser performances of diode-pumped Yb:CaF2 optical ceramics obtained with an energy-efficient process (Orale)

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