The evolution of regional language maintenance in Southern Alsace and Northern Catalonia: A longitudinal study of two regional communities

This chapter revisits two regional language situations that were examined by the authors in the early 1990s: Catalan and Alsatian. Questionnaire surveys were conducted in Alsace and Roussillon, to gauge usage of and attitudes towards the two languages. The findings were analysed in terms of ethnolinguistic vitality and of Fishman’s 1991 model of Reversing Language Shift, concluding that the future was cautiously optimistic, largely due to changing attitudes across Europe. Nearly a quarter of a century later, a longitudinal study of the two communities seeks to evaluate how the situation has changed. Using recent quantitative data, combined with a review of the linguistic landscape, the chapter reassesses the situation and offers a balanced and comparative analysis of the way in which the two linguistic areas have evolved over the last 25 years

Large-Scale Candidate Gene Analysis of HDL Particle Features

Background: HDL cholesterol (HDL-C) is an established marker of cardiovascular risk with significant genetic determination. However, HDL particles are not homogenous, and refined HDL phenotyping may improve insight into regulation of HDL metabolism. We therefore assessed HDL particles by NMR spectroscopy and conducted a large-scale candidate gene association analysis. Methodology/Principal Findings: We measured plasma HDL-C and determined mean HDL particle size and particle number by NMR spectroscopy in 2024 individuals from 512 British Caucasian families. Genotypes were 49,094 SNPs in >2,100 cardiometabolic candidate genes/loci as represented on the HumanCVD BeadChip version 2. False discovery rates (FDR) were calculated to account for multiple testing. Analyses on classical HDL-C revealed significant associations (FDR<0.05) only for CETP (cholesteryl ester transfer protein; lead SNP rs3764261: p = 5.6*10(-15)) and SGCD (sarcoglycan delta; rs6877118: p = 8.6*10(-6)). In contrast, analysis with HDL mean particle size yielded additional associations in LIPC (hepatic lipase; rs261332: p = 6.1*10(-9)), PLTP (phospholipid transfer protein, rs4810479: p = 1.7*10(-8)) and FBLN5 (fibulin-5; rs2246416: p = 6.2*10(-6)). The associations of SGCD and Fibulin-5 with HDL particle size could not be replicated in PROCARDIS (n = 3,078) and/or the Women's Genome Health Study (n = 23,170). Conclusions: We show that refined HDL phenotyping by NMR spectroscopy can detect known genes of HDL metabolism better than analyses on HDL-C

Vers une nouvelle identité galloise ?

ISBN : 978-2-901737-0 ; 271 p.International audienceQu'en est-il du pays de Galles au début du XXIe siècle ? L'Assemblée galloise a eu des effets bénéfiques dans de nombreux domaines : langues et cultures, économie et société. L'identité galloise s'est renforcée, et le pays entend désormais faire entendre sa voix, non seulement au sein du Royaume-Uni (plusieurs partis revendiquent aujourd'hui un statut comparable à celui de l'Ecosse pour le pays de Galles), mais aussi au sein de l'Europe

Robert Herrick et les poètes cavaliers

Abalain Hervé. Robert Herrick et les poètes cavaliers . In: XVII-XVIII. Bulletin de la société d'études anglo-américaines des XVIIe et XVIIIe siècles. N°19, 1984. pp. 45-58

IFREMER MAREGAMI. Buoy definition

The scope of the document is to present the preliminary structural assumptions concerning the buoys of the 2 given locations. The global definition of the buoy has to take into account the following constraints: * layout with specific entities as photovoltaic panels, shelter, boat landing area, anti-intrusion device… * defined swinging area because of the navigation channel proximity; * defined tensions in mooring lines in order to establish the fixed points type to install on the seabed; * knew the buoys behaviors.Étude de conception d'une bouée océanographique dédiée à un observatoire de fond de mer en mer de Marmara. Travail réalisé par le cabinet d'architecture navale SOFRESID sur un cahier des charges rédigé par le service SIIM, dans le cadre du projet MAREGAMI.

Le Pays de Galles au vingtième siècle (naissance d'une nouvelle identité)

BREST-BU Lettres (290192101) / SudocSudocFranceF

Burkhokderia cepacia et mucoviscidose (comparaison de souches isolées chez des patients suivis au centre de Perharidy à Roscoff par la technique du Multilocus Sequence Typing)

BREST-BU Médecine-Odontologie (290192102) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF