730 research outputs found

    KONTRA-RADIKALISASI AGAMA BERBASIS AJARAN TASAWUF DI INSTITUT AGAMA ISLAM NEGERI PEKALONGAN

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    This study aims to explore the strategy of counter-radicalization of religion among IAIN Pekalongan students. Qualitative research in the form of field research is descriptive-analytical. Data collection through interviews and documentation. Students who became informants, namely students of the Faculty of Tarbiyah and Teacher Training and the Faculty of Usuludin Adab, and Da'wah. Secondary data in the form of a variety of scientific research that is correlated with the core of the discussion. Meanwhile, the data analysis technique is through data reduction, data presentation, and data verification. The results of the study stated that the strategy of counter-radicalization of religion among IAIN Pekalongan students was through the internalization of Sufism teachings with two methods. First, the ta'lim method, namely through teaching various Sufism teachings in learning Sufism courses in the classroom, including the teachings of zuhud, tawasuth, and rahmatan lil alamin. Second, the ta'dib method, namely the habit of reading Asmaul Husna on student activities, such as starting learning in class, completing fardhu prayers in congregation, and at the opening of every religious activity. The strategy of counter-radicalization of religion in practice can lead to the formation of moderate religious understanding and social attitudes of students, neither extreme left nor right. The theoretical implication of this research shows that the application of Sufism teachings is compatible in shaping the character of moderate Islamic understanding and religious attitudes, so that it can become the basis of values as well as the paradigm of counter-radicalization of religion The limitation of this research is that it has not examined the role of the local government or local community leaders in the succession of the religious counter-deradicalization program at IAIN Pekalonga

    Mutation determination of rice by using RAPD primers

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    PCR is a powerful tool for the amplification of genetic sequences but sometimes, even though using an established PCR protocol that had been optimized and successful for the amplification of a particular DNA segment, use of that same protocol on a different region can result in a less than desirable outcome. Therefore, an experiment was conducted at Molecular biology laboratory of Malaysian Nuclear Agency during December 2016 to January 2017 used seeds of 6 indica rice cultivars. To conduce RAPD experiments for the rice species it was established the following reaction conditions for the final volume of 20 μl where 0.1 unit of Taq DNA polymerase, 0.4 μl of each dNTP, 2.5 mM MgCl2, 1 μl primer and 2.0 μl of DNA template. From this experiment, it is clear that after mutation the parent MR219 performed some genetic modification and produce genetically different variety namely NMR151, NMR152, ML3, ML10 and ML30. These mutant varieties have two different groups based on their mutation source and it is clear enough from their RAPD profile. Int. J. Agril. Res. Innov. & Tech. 9 (1): 1-7, June, 201

    Interpretasi Bawah Permukaan Daerah Sumber Air Panas Diwak-derekan Berdasarkan Data Magnetik

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    Research has been carried out using a magnetic method that aims to interpret the subsurface structure of the area hot springs Derekan - Diwak based on the total magnetic field anomaly data. It also aims to investigate the geothermal system in the area.Some 99 points measurement areas were measured using PPM (Proton Precession Magnetometer) geometrics type GSM19T models to get the value of the total magnetic field and two points as a base station simultaneously measured using the PPM G856X models. Measurement data is processed by the daily variation correction and IGRF (International Geomagnetic Reference Field) correction. The data has been used to create a contour corrected total magnetic field anomalies and subsurface cross sections involving the upward continuation and reduction to the poles.The results of study showed the total magnetic field anomaly closure pair of positive and negative closure indicate a fault zone below the surface. Interpretation is strengthened by the results of the modeling showed two faults of Derekan - Diwak areas trending southwest- northeast. This fault zone is a media outlet fluid to the surface in the area of geothermal systems

    Biochemical Study and Molecular Approaching on Eight Wild Herbals Used in Folk Medicine in Al-Baha Region, KSA

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    studies   describing   the   traditional   therapeutic   uses   of   natural   medicinal   and   aromatic   plants   have been established   in   Al-Baha   region, KSA.   In   this work, the antioxidant   activity   of   eight   herbals   plant   samples   from   Al-Baha   region   was   studied   using   different   solvents (ethanol, hexane   and water) to   evaluate   their   strong   and   total   lipid-soluble   antioxidant   and   water-soluble   antioxidant   activity (TLAC37,95 and TWAC37,95). The eight herbal plants were also molecularly   characterized   using   the   PCR-based   ISSR   markers. The studied samples demonstrated   valuable   and   variable   antioxidant   properties.   The   strong   antioxidant   capacity   of   Rumex   (Rumex   nervosus Vahl.)   samples   for   ethanolic   and   aqueous   extract   samples   was   the   highest   followed by Fringed Rue (Ruta chalepensis L.) samples (47.68 and 42.72 & 81.74 and 74.18   µmoles/g   respectively),   while   hexanic   extracts   of   Euryops   (Euryops   arabicus Steud. ex Jaub. & Spach) samples   revealed   the   highest   strong   antioxidant   capacity   followed   by   Fringed   Rue   samples   (23.67   and   13.83   µmoles/g   respectively).   Besides   that, ethanolic   extracts   of   Fringed   Rue   samples   demonstrated   the   highest   total   antioxidant   capacity   followed   by   olive   leaves (Olea europaea subsp. cuspidata (Wall. & G.Don) Cif.) samples (686.95 and 462.62 µmoles/g respectively), while aqueous   extracts   of   Rumex   samples   revealed   superior   total   antioxidant   capacity   followed   by   olive   leaves   samples   and   Fringed Rue samples (869.10, 837.21   and   743.75   Âµmoles/g   respectively.   But   the   hexanic   extracts   of   Fringed   Rue samples   revealed   valuable   total   antioxidant   capacity   followed by Rumex samples (127.83 and 38.00 µmoles/g respectively.   The   herbal   plants   of   Rumex, Fringed   Rue   and   olive revealed   huge   both   total   and   strong   antioxidant   activity.   In   the   present   study we began   an   initial   approach   to   authenticate   and   identify   different   plant species   in   our   study   using   inter-simple   sequence   repeats (ISSRs) molecular markers

    Activity of bovine parainfluenza type 3 virus in cattle in North Eastern Nigeria -A short communication

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    Parainfluenza type 3 virus (PI3V) is a primary agent of Bovine Shipping Fever worldwide. The activity of the virus was accessed through a sero-survey using the haemagglutination inhibition (HI) test. Out of 656 cattle sampled from Adamawa, Bauchi, Taraba and Borno States, 51.37% were seropositive. The reciprocal of HI titres ranged between 21 and 212. The geometric mean HI titres ranged from 106 in Borno State to 686 in Adamawa State. The  implication of these findings to the possible occurance of shipping fever along cattle routes is discussed

    STUDI KARAKTERISTIK PARAMAGNETIK DALAMSILIKON BERPORI DENGAN ESR

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    STUDI KARAKTERISTIK PARAMAGNETIK DALAMSILIKON BERPORI DENGAN ESR. Silikon berpori (PS) merupakan salah satu dari banyak bahan yang memperlihatkan gejala fotoluminisens dan elektroluminisens dalam daerah sinar tampak pada suhu kamar. Karakteristik yang menonjol untuk divais silikon adalah keberadaan interface oksida yang memisahkan gerbang metalik dan semikonduktor. Dangling bond-type defect (cacat tipe ikatan kosong) berada dalam antar muka dan dapat dideteksi menggunakan teknik ESR. PS telah difabrikasi dengan penganodisasian wafer c-Si (111) dalamlarutan asamfluorida (HF). Konsentrasi larutan HF dan waktu anodisasi divariasi. Spektrum ESR dari PS diukur menggunakan spektrometer X-band ESR pada suhu ruangan dengan medan sapuan 250 mT dan frekuensi 9,44 GHz. Hasil menunjukkan bahwa spektrum PS yang terbentuk oleh konsentrasi larutan HF 40% selama 60 menit (PS 40%-60) adalah garis spektrum lebar dengan faktor g adalah 2,2505. Penambahan konsentrasi HF sampai 48 % menyebabkan pengurangan intensitas signal dan pergeseran spektrum menuju nilai medan yang lebih tinggi. Faktor g dari spektrum ini sama dengan g = 2,0774. Untuk PS dengan konsentrasi di bawah 40 %, intensitas signal ESR tidak tampak. Untuk PS40%dan PS60%, intensitas signal ESR berkurang jika waktu anodisasi diturunkan dari 60 menit hingga 20 menit. Spektrum dapat diidentifikasi dari cacat tipe ikatan kosong pada interface antara dinding-dinding pori dan lapisan teroksidasi atau interface Si/SiO2

    Long-Term Outcomes of Everolimus Therapy in De Novo Liver Transplantation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

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    BACKGROUND: Risk of nephrotoxicity in liver transplant patients on calcineurin inhibitors (CnIs) is a concern. Several controlled trials reported benefit of everolimus (EVR) in minimizing this risk when combined with a reduced CnI dose. BACKGROUND: To systematically review the efficacy and safety of EVR, alone or with reduced CnI dose, as compared to CnI alone post-liver transplantation. METHODS: We searched MEDLINE, Scopus, and the Cochrane Library for randomized controlled trials comparing EVR- and CnI-based regimens post-liver transplantation. Assessment of studies and data extraction were undertaken independently. RESULTS: Eight studies were selected, describing 769 patients. Cockcroft-Gault GFR was higher at one (P = .05), 3, and 5 years (P = .030) in patients on EVR compared to those receiving CnI therapy. The composite endpoint of efficacy failure was similar between the 2 arms after 1, 3, and 5 years of study. More patients discontinued EVR due to adverse effects in 1 year; however, no difference was noted after 3 or 5 years. A higher rates of proteinuria, peripheral edema, and incisional hernia occurred in patients on EVR. CONCLUSIONS: The analysis confirms noninferiority of EVR and reduced CnI combination. Combination regimen resulted in better renal function compared to standard CnI therapy

    Oestradiol-17β plasma concentrations after intramuscular injection of oestradiol benzoate or oestradiol cypionate in llamas (Lama glama)

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    <p>Abstract</p> <p>Background</p> <p>Llamas (<it>Lama glama</it>) are induced ovulators and the process of ovulation depends on dominant follicular size. In addition, a close relationship between behavioural estrus and ovulation is not registered in llamas. Therefore, the exogenous control of follicular development with hormones aims to predict the optimal time to mate. Oestradiol-17β (E<sub>2</sub>) and its esters are currently used in domestic species, including camelids, in synchronization treatments. But, in llamas, there is no reports regarding the appropriate dosages to be used and most protocols have been designed by extrapolation from those recommended for other ruminants. The aim of the present study was to characterize plasma E<sub>2 </sub>concentrations in intact female llamas following a single intramuscular (i.m.) injection of two oestradiol esters: oestradiol benzoate (EB) and oestradiol cypionate (ECP).</p> <p>Methods</p> <p>Twelve non pregnant and non lactating sexually mature llamas were i.m. injected on day 0 with 2.5 mg of EB (EB group, n = 6) or ECP (ECP group, n = 6). Blood samples were collected immediately before injection, at 1, 6, 12, 24 h after treatment and then daily until day 14 post injection. Changes in hormone concentrations with time were analyzed in each group by analysis of variance (ANOVA) using a repeated measures (within-SS) design. Plasma E<sub>2 </sub>concentrations and area under the concentration-time curve (AUC) values were compared between groups by ANOVA. In all cases a Least-Significant Difference test (LSD) was used to determine differences between means. Hormonal and AUC data are expressed as mean ± S.E.M.</p> <p>Results</p> <p>Peak plasma E<sub>2 </sub>concentrations were achieved earlier and were higher in EB group than in ECP group. Thereafter, E<sub>2 </sub>returned to physiological concentrations earlier in EB group (day 5) than in ECP group (day 9). Although plasma E<sub>2 </sub>profiles differed over time among groups there were no differences between them on AUC values.</p> <p>Conclusions</p> <p>The i.m. injection of a single dose of both oestradiol esters resulted in plasma E<sub>2 </sub>concentrations exceeding physiological values for a variable period. Moreover, the plasma E<sub>2 </sub>profiles observed depended on the derivative of oestradiol administered. This basic information becomes relevant at defining treatment protocols including oestrogens in llamas.</p

    BIOINFORMATICS: INFLAMMATORY CYTOKINES AND ATTENUATION OF DIABETES HYPERCHOLESTEROLEMIA-INDUCED RENAL INJURY USING MORNING GLORY AND NECKLACE POD EXTRACTS

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      Objective: The present research in bioinformatics focuses on pharmacological effects of morning glory and necklace pod ethanolic extracts (MGE and NPE) on some biochemical parameters in high fat diet-induced hypercholesterolemia and streptozotocin-induced hyperglycemia in rats.Methods: Compared to atorvastatin; an anti-hypercholesterolemic (HC) and glibenclamide; an antidiabetic drug. Endothelium activation markers of soluble vascular cell adhesion molecule (VCAM)-1 and intercellular adhesion molecule (ICAM)-1 were determined using enzyme-linked immunosorbent assay. Creatinine, urea, and inflammatory biomarkers; C-reactive protein (CRP) and pro-inflammatory cytokines including tumor necrosis factor alpha (TNF-α) and interleukin (IL)-10 levels were also measured in serum of different therapeutic groups.Results: Significant decrease in ICAM-1 level with MGE and NPE supplemented to normal rats as compared to untreated control with percentages decrease 17.80 and 12.00% was observed. Insignificant change was detected in VCAM-1 level. Profound amelioration in CRP, total urea and creatinine levels by NPE treatment. Creatinine, urea, CRP, and TNF-α level were significantly increased in hyperglycemic (HG)-HC rats. However, IL-10 level showed a significant decrease. Meanwhile, histopathological investigation of the kidney and heart was carried out. Image recognition system for kidney and heart images was developed to diagnose their diseases. Tested extract attenuated creatinine, urea, CRP, and TNF-α level. Hyperglycemia and hypercholesterolemia linked kidney disorders were relieved.Conclusion: In vivo oral administration with each extract declared suppression of cytokines mediated inflammation, vascular function leading to infiltration reduction of renal macrophage together with lowering in kidney indices and ameliorate renal tissues architectures in HG-HC rats
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