Interpretasi Bawah Permukaan Daerah Sumber Air Panas Diwak-derekan Berdasarkan Data Magnetik

Research has been carried out using a magnetic method that aims to interpret the subsurface structure of the area hot springs Derekan - Diwak based on the total magnetic field anomaly data. It also aims to investigate the geothermal system in the area.Some 99 points measurement areas were measured using PPM (Proton Precession Magnetometer) geometrics type GSM19T models to get the value of the total magnetic field and two points as a base station simultaneously measured using the PPM G856X models. Measurement data is processed by the daily variation correction and IGRF (International Geomagnetic Reference Field) correction. The data has been used to create a contour corrected total magnetic field anomalies and subsurface cross sections involving the upward continuation and reduction to the poles.The results of study showed the total magnetic field anomaly closure pair of positive and negative closure indicate a fault zone below the surface. Interpretation is strengthened by the results of the modeling showed two faults of Derekan - Diwak areas trending southwest- northeast. This fault zone is a media outlet fluid to the surface in the area of geothermal systems

Diversity study of Drumstick (Moringaoleifera Lam.) using Microsatellite markers

The study of the magnitude of genetic diversity existing within thirty one accessions of Moringaoleifera collections made within and outside Nigeria was conducted using ten Randomised Amplified Polymorphic DNA and tenMicrosattellite markers.None of the RAPD showed amplification bands. Five out of the Microsattellites markersamplified, four primers MO1, MO10, MO15 and MO41 were polymorphic in nature while the marker MO6 produced only a monomorphic band.PIC value was highest for the primer MO41 with 0.75 followed by primer MO1 with 0.68 while, the lowest PIC value was recorded by the primer MO15 with 0.11.A total of 19 alleles were produced by the four primers and the number of alleles ranged from two to nine with an average of 4.75 alleles per primer. The maximum number allele frequency was generated by primer MO15 followed by MO10.The gene diversity varied from 0.12 to 0.78 with an average of 0.52, PIC content of the SSR primers ranged from 0.11 to 0.75 with an average of 0.48 with primers MO 41 followed closely by primer MO1 having maximum numbers of allele number, PIC and gene diversity. Hence, the primer pairs MO41and MO1 can be considered in future molecular studies of Moringaoleifera.The Cluster analysis was able to group the thirty one accessions into two main clusters with four sub clusters. Six of the accessions were found to be duplicated or closely related with one or two other accessions having 0.00 genetic distances between them. The clusters were having some accessions grouped based on same area of collection, however there still existed groupings that were not having link with area of collection

Comparative Study of Zootechnical Performances and Survival Rates in Rainbow Trout Subjected to Two Foods with Different Formulation

Considering its economic and halieutic interest, the rainbow trout (Oncorhynchus mykiss, Walbaum, on 1792) is one of the species the most appreciated in the world, in particular for the sports fishing. To compare the effects of two food of different formulation, (the one premises(place) used by the center of salmon farming and the other one imported) on some biological parameters of the trout rainbow, an experimental study was realized between 1st Mars and June 15th, 2016 in the National Center of Hydrobiology and Fish farming of Azrou on 2000 fish fry stemming from the same prize of eggs and restarted randomly in 4 rectangular ponds fed with fresh water and fed four times by days during 107 days. The obtained results show good that the best performances of growth in length and in weight, the survival rate and feed efficiency are attributed to the imported food

The Fiqh Paradigm in Strengthening Moderate Religiosity Through The Study of Kitab Turats in Pesantren

The purpose research is to find out the transmission of the fiqh paradigm in strengthening moderate religiosity through the study of kitab turats at Hidayatul Mubtadi\u27en Pekalongan Islamic Boarding School. Data were obtained through observation, interviews and documentation. This study confirms that the study of the book of Turats contains the dimensions of fiqh as a paradigm for strengthening the religiosity of its students, including the value of hifz\u27ird in strengthening humanist religiosity through the transformation of anti-violence values (al la unf) from the material of the book of Birrul Walidain and Tarbiyatul Walad. This value transformation can equip an ethical paradigm in upholding human values. The value of hifz ummah in strengthening pluralist diversity through the transformation of the value of tasamuh (tolerance), and i\u27tiraf al-\u27urf (friendly to culture) from the material in kitab at-Tibyan and kitab Hujjah Ahlussunnah wal Jama\u27ah. This value transformation can equip students to have an ethical paradigm in behavior and beliefs that respect social and cultural diversity. Furthermore, the value of hifz waton in strengthening nationalist religiosity through the transformation of the value of love for the homeland (al-muwathanah) from the material of Kitab at-Tahliyah wa at-Targhib and Kitab Mukhtarul Ahadith. This value transformation can equip students to have an ethical paradigm in the form of moderate attitudes and views in maintaining the integration of state life. The findings of this study confirm that the values of maqasid sharia and tarbiyah can be integrated in the transmission of moderate religious education in Islamic education activities

Quantitative cross-species extrapolation between humans and fish: The case of the anti-depressant fluoxetine

This article has been made available through the Brunel Open Access Publishing Fund.Fish are an important model for the pharmacological and toxicological characterization of human pharmaceuticals in drug discovery, drug safety assessment and environmental toxicology. However, do fish respond to pharmaceuticals as humans do? To address this question, we provide a novel quantitative cross-species extrapolation approach (qCSE) based on the hypothesis that similar plasma concentrations of pharmaceuticals cause comparable target-mediated effects in both humans and fish at similar level of biological organization (Read-Across Hypothesis). To validate this hypothesis, the behavioural effects of the anti-depressant drug fluoxetine on the fish model fathead minnow (Pimephales promelas) were used as test case. Fish were exposed for 28 days to a range of measured water concentrations of fluoxetine (0.1, 1.0, 8.0, 16, 32, 64 μg/L) to produce plasma concentrations below, equal and above the range of Human Therapeutic Plasma Concentrations (HTPCs). Fluoxetine and its metabolite, norfluoxetine, were quantified in the plasma of individual fish and linked to behavioural anxiety-related endpoints. The minimum drug plasma concentrations that elicited anxiolytic responses in fish were above the upper value of the HTPC range, whereas no effects were observed at plasma concentrations below the HTPCs. In vivo metabolism of fluoxetine in humans and fish was similar, and displayed bi-phasic concentration-dependent kinetics driven by the auto-inhibitory dynamics and saturation of the enzymes that convert fluoxetine into norfluoxetine. The sensitivity of fish to fluoxetine was not so dissimilar from that of patients affected by general anxiety disorders. These results represent the first direct evidence of measured internal dose response effect of a pharmaceutical in fish, hence validating the Read-Across hypothesis applied to fluoxetine. Overall, this study demonstrates that the qCSE approach, anchored to internal drug concentrations, is a powerful tool to guide the assessment of the sensitivity of fish to pharmaceuticals, and strengthens the translational power of the cross-species extrapolation

FIQH SIYASAH PARADIGM IN THE INDICATORS OF MODERATE RELIGIOUS EDUCATION IN INDONESIA

AbstractThe mainstreaming of moderate religious indicators in Indonesia in the realm of practice is not always responded positively by all communities. Regardless of the pros and cons, it is important to realize that the mainstreaming is a government policy to build harmony between religious, cultural and state life in Indonesia. The purpose of this qualitative study in the form of a literature review is to identify the fiqh siyasah syar'iyah paradigm on the orientation of moderate religious education contained in the indicators of religious moderation in Indonesia. This study uses a content analysis approach.  Explanations related to four indicators of moderate religiosity formulated by the Ministry of Religious Affairs of the Republic of Indonesia became the main data of the study obtained through documentation techniques. This study concludes that there are fiqh siyasah syar'iyah values in the orientation of religious moderation indicators in Indonesia that contain the dissemination of moderate religious education values, including the value of shura on indicators that require strengthening the values of pluralist and humanist religious education. Then, the value of wasathiyah on indicators that require strengthening the values of nationalist and accommodating religious education on cultural wisdom. This study shows that the indicators of moderate religiosity in Indonesia contain various legal ethical values and Islamic social education as a basis for political policy in building harmonious relations of religious, state and cultural life.AbstrakPengarustamaan indikator keberagamaan moderat di Indonesia pada ranah praksisya tidak senantiasa direspons positif oleh semua masyarakat. Terlepas dari pro-kontra yang ada, penting untuk disadari pengarustamaan tersebut menjadi kebijakan pemerintah untuk membangun harmoni antara kehidupan beragama, berbudaya dan bernegara di Indonesia. Tujuan studi kualitatif dalam bentuk kajian pustaka ini untuk mengidentifikasi paradigma fikih siyasah syar’iyah pada orientasi pendidikan keberagamaan moderat yang termuat dalam indikator moderasi beragama di Indonesia. Studi ini menggunakan pendekatan analisis isi. Penjelasan terkait empat indikator keberagamaan moderat yang dirumuskan oleh kementrian Agama Republik Indonesia menjadi data pokok studi yang diperoleh melalui teknik dokumentasi. Studi ini menyimpulkan adanya nilai-nilai fikih siyasah syar’iyah pada orientasi indikator moderasi beragama di Indonesia yang memuat diseminasi nilai-nilai pendidikan keberagamaan moderat, antara lain nilai syura pada indikator yang menghendaki penguatan nilai-nilai pendidikan keberagamaan pluralis dan humanis. Kemudian, nilai wasathiyah pada indikator yang menghendaki penguatan nilai-nilai pendidikan keberagamaan nasionalis dan akomodatif pada kearifan budaya. Studi ini menunjukan indikator keberagamaan moderat di Indonesia memuat berbagai nilai legal etik dan pendidikan sosial keberagamaan Islam sebagai basis kebijakan politik dalam membangun relasi harmoni kehidupan beragama, bernagara, dan berbudaya. 

Recent progress in understanding and projecting regional and global mean sea-level change

Considerable progress has been made in understanding the present and future regional and global sea level in the 2 years since the publication of the Fifth Assessment Report (AR5) of the Intergovernmental Panel on Climate Change. Here, we evaluate how the new results affect the AR5’s assessment of (i) historical sea level rise, including attribution of that rise and implications for the sea level budget, (ii) projections of the components and of total global mean sea level (GMSL), and (iii) projections of regional variability and emergence of the anthropogenic signal. In each of these cases, new work largely provides additional evidence in support of the AR5 assessment, providing greater confidence in those findings. Recent analyses confirm the twentieth century sea level rise, with some analyses showing a slightly smaller rate before 1990 and some a slightly larger value than reported in the AR5. There is now more evidence of an acceleration in the rate of rise. Ongoing ocean heat uptake and associated thermal expansion have continued since 2000, and are consistent with ocean thermal expansion reported in the AR5. A significant amount of heat is being stored deeper in the water column, with a larger rate of heat uptake since 2000 compared to the previous decades and with the largest storage in the Southern Ocean. The first formal detection studies for ocean thermal expansion and glacier mass loss since the AR5 have confirmed the AR5 finding of a significant anthropogenic contribution to sea level rise over the last 50 years. New projections of glacier loss from two regions suggest smaller contributions to GMSL rise from these regions than in studies assessed by the AR5; additional regional studies are required to further assess whether there are broader implications of these results. Mass loss from the Greenland Ice Sheet, primarily as a result of increased surface melting, and from the Antarctic Ice Sheet, primarily as a result of increased ice discharge, has accelerated. The largest estimates of acceleration in mass loss from the two ice sheets for 2003–2013 equal or exceed the acceleration of GMSL rise calculated from the satellite altimeter sea level record over the longer period of 1993–2014. However, when increased mass gain in land water storage and parts of East Antarctica, and decreased mass loss from glaciers in Alaska and some other regions are taken into account, the net acceleration in the ocean mass gain is consistent with the satellite altimeter record. New studies suggest that a marine ice sheet instability (MISI) may have been initiated in parts of the West Antarctic Ice Sheet (WAIS), but that it will affect only a limited number of ice streams in the twenty-first century. New projections of mass loss from the Greenland and Antarctic Ice Sheets by 2100, including a contribution from parts of WAIS undergoing unstable retreat, suggest a contribution that falls largely within the likely range (i.e., two thirds probability) of the AR5. These new results increase confidence in the AR5 likely range, indicating that there is a greater probability that sea level rise by 2100 will lie in this range with a corresponding decrease in the likelihood of an additional contribution of several tens of centimeters above the likely range. In view of the comparatively limited state of knowledge and understanding of rapid ice sheet dynamics, we continue to think that it is not yet possible to make reliable quantitative estimates of future GMSL rise outside the likely range. Projections of twenty-first century GMSL rise published since the AR5 depend on results from expert elicitation, but we have low confidence in conclusions based on these approaches. New work on regional projections and emergence of the anthropogenic signal suggests that the two commonly predicted features of future regional sea level change (the increasing tilt across the Antarctic Circumpolar Current and the dipole in the North Atlantic) are related to regional changes in wind stress and surface heat flux. Moreover, it is expected that sea level change in response to anthropogenic forcing, particularly in regions of relatively low unforced variability such as the low-latitude Atlantic, will be detectable over most of the ocean by 2040. The east-west contrast of sea level trends in the Pacific observed since the early 1990s cannot be satisfactorily accounted for by climate models, nor yet definitively attributed either to unforced variability or forced climate change