88,945 research outputs found

    Corneal Dermoid

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    A 20 years old boy presented with left corneal mass. The mass involved entire cornea extending to the sclera. The mass had a skin like surface and protruded outside the palpebral aperture. The eye with the mass was excised .The histopathology report confirmed the diagnosis of corneal dermoid. This late presentation of huge corneal dermoid extending to sclera is first such report in the literature

    Over the counter ophthalmic drug misuse, are we aware?

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    Aim: To investigate the misuse of ā€˜over the counterā€™ ophthalmic medications in our city. Method: Responses of a structured questionnaire covering various aspects of over the counter drug use was obtained from pharmacy workers in and around our city. Results: Eighty nine pharmacy workers took part in this crossā€“sectional study. An average number of seven patients per day with ophthalmic complaints were seen by the pharmacy workers. Dispensing over the counter was practiced by 89.9% of the pharmacists. The most common complaint of the patients visiting the pharmacy, was redness and itching (86.5%). Antibiotics (96.6%) were the most common eye drops dispensed over the counter, followed by steroids (55.1%), decongestants (54.1%), antibiotic-steroid combination eye drops (29.2%) and lubricants (16.8%). Awareness regarding complications of steroid use was seen in 40.6% of pharmacists. 6.7% pharmacists had seen patients with complications following use of over the counter medications. In our study, majority of the eye drops dispensed were prescription drugs. Conclusion: Availability of prescription eye drops over the counter is an immense public threat. Educating the pharmacist and the population can decrease ocular morbidity. Research into methods to effectively deal with over-the-counter drug misuse is required and law can be enforced based on the findings

    Association between pretreatment haemoglobin levels and morphometric characteristics of the tumour, response to neoadjuvant treatment and long-term outcomes in patients with locally advanced rectal cancers

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    Aim The study was carried out to investigate whether pretreatment haemoglobin (Hb) levels act as a biomar- ker in the management of patients with locally advanced rectal cancer. Method\ud We prospectively collected data on all patients within our cancer network with localized low rectal cancer treated with preoperative radiotherapy/chemora- diotherapy at Mount Vernon Centre for Cancer Treat- ment between March 1994 and July 2008. Pretreatment Hb level was assessed as an independent variable for the whole study sample and dichotomised at a value of 12 g/dl. A multivariate analysis of covariance (MANCOVA) was conducted on parameters that had significant association on univariate analysis of covariance (ANCOVA) and cor- relational (Kendall tau/Pearson) analyses. Kaplan ā€“ Meier survival analysis and Cox proportional hazard models were used to determine significant prognostic markers. Statistical significance was set at 0.05. Results 463 patients (male/female 2:1; median age = 66 years, interquartile range = 56.5 ā€“ 73.0) were included in the analysis. There was significant tumour response of T stage ( P < 0.001) and N stage ( P < 0.001), with 17.6% of patients achieving a pathological complete response. Pretreatment Hb value was inversely related to the craniocaudal vertical tumour length ( P = 0.02) and pretreatment T stage of the tumour ( P = 0.01). Patients with Hb levels of < 12 g/dl and moderately differenti- ated adenocarcinoma were less responsive. Local recur- rence was more common in patients with a pretreatment Hb of < 12 g/dl (hazard ratio = 1.78) over a median follow up of 24 months, but this was not statistically significant ( P = 0.08). Conclusion The pretreatment Hb level might be used as a biomarker of rectal tumour morphology, response to neoadjuvant chemoradiation and risk of local recur- renc

    The Heat Kernel on AdS_3 and its Applications

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    We derive the heat kernel for arbitrary tensor fields on S^3 and (Euclidean) AdS_3 using a group theoretic approach. We use these results to also obtain the heat kernel on certain quotients of these spaces. In particular, we give a simple, explicit expression for the one loop determinant for a field of arbitrary spin s in thermal AdS_3. We apply this to the calculation of the one loop partition function of N=1 supergravity on AdS_3. We find that the answer factorizes into left- and right-moving super Virasoro characters built on the SL(2, C) invariant vacuum, as argued by Maloney and Witten on general grounds.Comment: 46 pages, LaTeX, v2: Reference adde

    Magnetoacoustics of the Low-Dimensional Quantum Antiferromagnet Cs2CuCl4 with Spin Frustration

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    We report on results of sound-velocity and sound-attenuation measurements in the triangular-lattice spin-1/2 antiferromagnet Csā‚‚CuClā‚„ (T<sub>N</sub> = 0.6 K), in external magnetic fields up to 14 T, applied along the <em>b</em> axis, and at temperatures down to 300 mK. The results are analyzed with a quasi-two-dimensional hard-core boson theory based on exchange-striction coupling. There is a good qualitative agreement between theoretical and experimental results.Citation: Sytcheva, A. et al. (2010). 'Magnetoacoustics of the low-dimensional quantum antiferromagnet Csā‚‚CuClā‚„', Journal of Low Temperature Physics, 159(1-2), 109-113. [Available at http://www.springer.com/materials/journal/10909]. Ā© The Authors 2010. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any non-commercial use, distribution, and reproduction in any medium, provided the original authors and source are credited.

    Syzygium Aromaticum (Clove) Effect on Catalase Activity Due to Carbon Tetrachloride-induced Oxidative Stress in Rat Liver

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    Background: Clove is known as antioxidant spice that used in cigarettes, spice for food/soup, and traditional medicine. It is believed that clove could protect smokers from cigarette-free radicals. Otherwise, study on clove as an antioxidant was still confused.Objective: To reveal that clove can overcome carbon tetra chloride (CCl4) and its free radical derivesMethod: This study was an experimental research, using 20 Wistar rats that were divided into 4 groups, Group 1 (CCl4 + cloves 3), group 2 (CCl4 + cloves 1), group 3 (normal control, without being offered treatment), group 4 (positive control, induced by CCl4 and followed by 100 mg alpha-tocopherol), and group 5 (negative control, only induced by CCl4). Rat livers were homogenized and followed with CAT activity measurement using spectrophotometry method of Mates.Results: There was a significant difference in mean between the groups (p= 0,001). Further test, the Post Hoc showed that there is a significance different between group 1 and 4 (p=0.008), 1 and 5 (p=0.001), 2 and 5 (p=0.001), 3 and 5 (p=0.001), and 4 and 5 (p=0.007). Group 1 (CCl4+Clove3) has the highest catalase activity.Conclusion: Syzygium aromaticum (clove) oral administration with the dose of 200 mg/kg rat body weight against 0.55 mg/kgBW CCl4 show increased of catalase activity but did not overcome the oxidative stress
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