8 research outputs found

    A emergência do paradigma do sensível

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    Resumo A dimensão do sensível emerge de um contato direto e íntimo com o corpo, a partir do qual o praticante desenvolve uma nova maneira de relacionar-se consigo mesmo, com os outros e com o mundo. Dessa relação, caracterizada pela presença de si, surge uma nova forma de conhecimento. Palavras-chave: Sensibilidade, Corpo, Processos de aprendizagem. Abstract The dimension of the sensible emerges out of a direct and intimate contact with the body, from which the practitioner develops a new way to interact with himself, with the others and with the world. From this relation, which is characterized by the presence of the self, a new form of knowledge emerges. Keywords: Sensitivity, Body, Processes of learning

    The VTP project : modular abstract syntax specification

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    This report examines the modular specification of abstract syntaxes. We describe an abstract syntax as a collection of parameterized modules encapsulating operator and sort definitions along with some basic operations on them. The sort extension from one module into another one is the most remarquable of these operations. This proposition takes much of its source from standard ML module language. This report is a part of a series of report on the VTP project

    Algebre de processus et synchronisation

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    Nous introduisons ici un calcul de processus fondé sur une composition parallèle asynchrone, et quelques primitives de synchronisation. Nous montrons qu'on peut y formuler de nombreux mécanismes de synchronisation ; en particulier il s'avère équivalent au calcul synchrone de R. Milner. Nous évaluons sa puissance d'expression en termes de langages de comportements

    Global Egr1-miRNAs Binding Analysis in PMA-Induced K562 Cells Using ChIP-Seq

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    Although much is known about microRNAs' regulation in gene expression and their contributions in cell fate, to date, globally lineage-(cell-) specific identification of the binding events between a transcription factor and its targeting microRNA genes is still waiting for elucidation. In this paper, we performed a ChIP-Seq experiment to find the targeting microRNA genes of a transcription factor, Egr1, in human erythroleukemia cell line K562. We found Egr1 binding sites near the promoters of 124 distinct microRNA genes, accounting for about 42% of the miRNAs which have high-confidence predicted promoters (294). We also found EGR1 bind to another 63 pre-miRNAs. We chose 12 of the 187 microRNAs with Egr1 binding sites to perform ChIP-PCR assays and the positive binding signal from ChIP-PCR confirmed the ChIP-Seq results. Our experiments provide the first global binding profile between Egr1 and its targeting microRNA genes in PMA-treated K562 cells, which may facilitate the understanding of pathways controlling microRNA biology in this specific cell line

    The VTP project : modular abstract syntax specification

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    SIGLEAvailable at INIST (FR), Document Supply Service, under shelf-number : 14802 E, issue : a.1990 n.1219 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc
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