191 research outputs found

    White soul paintings

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    I call my paintings pictures of "white soul." I do this in order to draw upon the associations familiar in the term "black soul:" a sense of pride in self and race, qualities of vigor and endurance, the rich, ironic mixtures of the sensual and spiritual in human experience, the timid or vigorous assertion of self which is mixed with its incomplete defeat. "Jellyroll" Morton said you should never forget the weeping along with all the joy in his music. Nor should the viewers of my portraits. I know the poor white rural people of northern Virginia and I see in their faces and surroundings the features of the human condition as I also have experienced it with its ambiguous mix of good and evil, its fair possibilities and wrinkled limitations, its humble or extravagant hopes and capacity to endure beyond vanities. I try to portray my subjects' ugliness and their beauty, their honesty and their self-deceptions through my knowledge of them and through an exploration of myself. I think that I relate to my subjects as that more impersonal portrayer of humanity did when he said of his heroine: "Madame Bovary, c'est moi.

    The town that made monday, part I

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    There they taught her modesty, chastity, silence, obedience... She did as she was told, but it was all very confusing, because she could not understand why the things that happen outside of people were so different from what she felt inside of her.--From "Virgin Violeta" by Katherine Anne Porter In studying human memory, psychologists encounter a phenomenon called the Reminiscence Bump: the period in which a substantial proportion of a person's memories in his or her life cluster between the ages of ten and thirty. We remember our young adulthood vividly, and the choices we make in those tender years often dramatically shape the way the rest of our lives unfold. In this first half of my novel, I examine the inner lives of two young people, Dex and Nore, how they encounter and challenge the pressures and traumas placed upon them by the society of a rural Texas town in the early 1980s. How does a young woman survive with a child born out of wedlock, in a world run by oil men and homecoming queens, preachers and football boosters? How does a young man shore up under the weight of seeing his athletic prowess, his self-worth as determined by the town, peak at eighteen? Why would someone choose not to raise their own child, and what prior decisions eventually culminate in that choice? In this first half of the novel, I explore the fraught relationship between mothers and daughters, young men and young women--anticipating a deeper excavation of these questions of parenthood, love, and forgiveness in part II

    A History Of Linwood College

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    The history of Linwood College has not been written. The college deserves a written chronicle of its life and contributions, for it existed for almost forty years and made a definite contribution to education in North Carolina and nearby states. The documents and other sources from which an accurate history can be constructed, though once plentiful, are now scarce, and the remaining few are constantly diminishing. The problem of the writer is to discover and gather all available information and from this construct as accurate a record as possible

    ADHD Traits, Emotion Dysregulation, And Romantic Relationship Satisfaction In College Students

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    A few studies have shown that increased emotion dysregulation in adolescents and adults with ADHD is associated with lower romantic relationship satisfaction (Bodalski et al., 2018; Maherio et al., 2020). The aim of the current study is to examine the relationship between the aforementioned variables in college students. The sample consists of 135 female and 21 male college students aged “18” to “26 and older.” The Difficulties in Emotion Regulation Scale (DERS; Gratz & Roemer, 2004) was used to assess emotion dysregulation, along with the Couples Satisfaction Index (CSI-16; Funk & Rogge, 2007) for romantic relationship satisfaction. The DSM-5 Current Symptoms Questionnaire (APA, 2013) was used to assess ADHD traits. Additionally, participants were given the Conflict Measure (Gordon & Chen, 2016) and the Conflict Resolution Style Inventory (Self-Rating; CRSI-Self; Kurdek, 1994). Bivariate correlation analyses revealed that all independent and dependent variables were significantly correlated. The final model in our hierarchical regression analysis was statistically significant, but the only individual significant predictor of romantic relationship satisfaction was experienced conflict. Due to the simple correlations between all variables, however, the results may suggest that, rather than having no effect, ADHD traits and emotion dysregulation influence experienced conflict in relationships, which is likely a direct contributor to romantic relationship dissatisfaction. Future studies should verify these results in more diverse samples and with individuals who have an official diagnosis of ADHD

    In vitro culturing of porcine tracheal mucosa as an ideal model for investigating the influence of drugs on human respiratory mucosa

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    It has been previously shown that fresh mucosa from different mammals could serve as raw material for in vitro culturing with the differentiation of cilia, which are the most important morphological structures for the function of the mucociliary system. Increasing legal restrictions on the removal of human tissue and changing surgical techniques have led to a lack of fresh human mucosa for culturing. Most of the animals that have been used as donors up to now are genetically not very close to human beings and must all be sacrificed for such studies. We, therefore, established a modified system of culturing mucosa cells from the trachea of pigs, which is available as a regular by-product after slaughtering. With respect to the possibility of developing “beating” cilia, it could be shown that the speed of cell proliferation until adhesion to the coated culture dishes, the formation of conjunctions of cell clusters and the proliferation of cilia were comparable for porcine and human mucosa. Moreover, it could be demonstrated that the porcine cilia beat frequency of 7.57 ± 1.39 Hz was comparable to the human mucosa cells beat frequency of 7.3 ± 1.4 Hz and that this beat frequency was absolutely constant over the investigation time of 360 min. In order to prove whether the reaction to different drugs is comparable between the porcine and human cilia, we initially tested benzalkonium chloride, which is known to be toxic for human cells, followed by naphazoline, which we found in previous studies on human mucosa to be non-toxic. The results clearly showed that the functional and morphological reactions of the porcine ciliated cells to these substances were similar to the reaction we found in the in vitro cultured human mucosa

    18^{18}F-Fluoride and 18^{18}F-Fluorodeoxyglucose Positron Emission Tomography After Transient Ischemic Attack or Minor Ischemic Stroke: Case-Control Study.

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    BACKGROUND: Combined positron emission tomography (PET) and computed tomography (CT) can assess both anatomy and biology of carotid atherosclerosis. We sought to assess whether 18^{18}F-fluoride or 18^{18}F-fluorodeoxyglucose can identify culprit and high-risk carotid plaque. METHODS AND RESULTS: We performed 18^{18}F-fluoride and 18^{18}F-fluorodeoxyglucose PET/CT in 26 patients after recent transient ischemic attack or minor ischemic stroke: 18 patients with culprit carotid stenosis awaiting carotid endarterectomy and 8 controls without culprit carotid atheroma. We compared standardized uptake values in the clinically adjudicated culprit to the contralateral asymptomatic artery, and assessed the relationship between radiotracer uptake and plaque phenotype or predicted cardiovascular risk (ASSIGN score [Assessing Cardiovascular Risk Using SIGN Guidelines to Assign Preventive Treatment]). We also performed micro PET/CT and histological analysis of excised plaque. On histological and micro PET/CT analysis, 18^{18}F-fluoride selectively highlighted microcalcification. Carotid 18^{18}F-fluoride uptake was increased in clinically adjudicated culprit plaques compared with asymptomatic contralateral plaques (log10_{10} standardized uptake valuemean_{mean} 0.29±0.10 versus 0.23±0.11, P=0.001) and compared with control patients (log10_{10} standardized uptake valuemean_{mean} 0.29±0.10 versus 0.12±0.11, P=0.001). 18^{18}F-Fluoride uptake correlated with high-risk plaque features (remodeling index [r=0.53, P=0.003], plaque burden [r=0.51, P=0.004]), and predicted cardiovascular risk [r=0.65, P=0.002]). Carotid 18^{18}F-fluorodeoxyglucose uptake appeared to be increased in 7 of 16 culprit plaques, but no overall differences in uptake were observed in culprit versus contralateral plaques or control patients. However, 18^{18}F-fluorodeoxyglucose did correlate with predicted cardiovascular risk (r=0.53, P=0.019), but not with plaque phenotype. CONCLUSIONS: 18^{18}F-Fluoride PET/CT highlights culprit and phenotypically high-risk carotid plaque. This has the potential to improve risk stratification and selection of patients who may benefit from intervention.Dr Vesey and the study were funded by program grants from the British Heart Foundation (PG12/8/29371) and Chest Heart and Stroke Scotland (R13/A147). Dr Jenkins, Vesey, Dweck, and Newby are supported by the British Heart Foundation (FS/14/78/31020, CH/09/002) and the Wellcome Trust (WT103782AIA). Dr Dweck is the recipient of the Sir Jules Thorn Biomedical Research Award 2015. The Wellcome Trust Clinical Research Facility and the Clinical Research Imaging Centre are supported by National Health Service (NHS) Research Scotland (NRS) through NHS Lothian. Dr Beek is supported by the Scottish Imaging Network—a Platform of Scientific Excellence (SINAPSE). Dr Rudd is part-supported by the National Institute for Health Research Cambridge Biomedical Research Centre, the British Heart Foundation, and the Wellcome Trust

    Managing software engineers and their knowledge

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    This chapter begins by reviewing the history of software engineering as a profession, especially the so-called software crisis and responses to it, to help focus on what it is that software engineers do. This leads into a discussion of the areas in software engineering that are problematic as a basis for considering knowledge management issues. Some of the previous work on knowledge management in software engineering is then examined, much of it not actually going under a knowledge management title, but rather “learning” or “expertise”. The chapter goes on to consider the potential for knowledge management in software engineering and the different types of knowledge management solutions and strategies that might be adopted, and it touches on the crucial importance of cultural issues. It concludes with a list of challenges that knowledge management in software engineering needs to address
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