Fibrolamellar Hepatocellular Carsinoma “It is not a Ordinary Case for Mediterranean Countries”

The fibrolamellar variant of hepatocellular carcinoma (HCC) is an uncommon tumour with distinctive clinical and histological features. Although the first case of fibrolamellar hepatocellular carcinoma (FI-HCC) was described by Edmondson in 1956, and later confirmed in five patients by Peters, the majority of reports followed those of Berman et al. and Craig et al. 1,2

The Effects Of Oligofructose And Polydextrose On Metabolic Control Parameters In Type-2 Diabetes

Objective: This study investigated the effects of oligofructose and polydextrose on metabolic control in Type-2 diabetes. Methodology: Twenty voluntary, postmenopausal, total cholesterol (TC)/HDL-cholesterol (HDL-C) ratios >4.5, female, Type-2 diabetes patients were included. The study was performed in four periods, with the baseline as the period one. In periods two and four, the patients consumed individual diabetic diets for eight weeks. In period three, they consumed 20g of oligofructose and potydextrose mixture in 40g sweetener (in powdered form), added to their diets for six weeks. Results: Prebiotic soluble fiber sources (oligofructose and polydextrose) significantly decreased fasting and postprandial (2-hour) blood glucose, glycosylated hemoglobin, TC, LDL-cholesterol (LDL-C), TC/HDL-C and LDL-C/HDL-C ratios, triglyceride, VLDL-cholesterol, lipoprotein (a), systolic and diastolic blood pressures (p0.05) compared to the initial values, respectively. Conclusion: Individual diabetic diets supplemented with prebiotics improved metabolic control in Type-2 diabetes.Wo