Dispersive ππ→KKˉ\pi\pi\rightarrow K\bar K amplitude and giant CP violation in B to three light-meson decays at LHCb

The LHCb collaboration has recently reported the largest CP violation effect from a single amplitude, as well as other giant CP asymmetries in several $B$-meson decays into three charmless light mesons. It is also claimed that this is predominantly due to $\pi\pi\rightarrow K\bar K$ rescattering in the final state, particularly in the 1 to 1.5 GeV region. In these analyses the $\pi\pi\rightarrow K\bar K$ amplitude is by default estimated from the $\pi\pi$ elastic scattering amplitude and does not describe the existing $\pi\pi\rightarrow K\bar K$ scattering data. Here we show how the recent model-independent dispersive analysis of $\pi\pi\rightarrow K\bar K$ data can be easily implemented in the LHCb formalism. This leads to a more accurate description of the asymmetry, while being consistent with the measured scattering amplitude and confirming the prominent role of hadronic final state interactions, paving the way for more elaborated analyses.Comment: 9 pages, 6 figures. Minor corrections and discussions were added. Extended appendix with an additional improved model of the S-wave. Final version to appear in Phys.Rev.Let

Aragonian stratigraphy reconsidered, and a re-evaluation of the middle Miocene mammal biochronology in Europe

The recently collected fauna of Armantes 1A in Chron C5Br of the Armantes section necessitates reinterpretation of the previous bio- and magnetostratigraphical correlations between the Armantes and Vargas sections (Calatayud-Daroca Basin, Central Spain) [W. Krijgsman, M. Garcés, C.G. Langereis, R. Daams, J. van Dam, A.J. van der Meulen, J. Agustí, L. Cabrera, A new chronology for the Middle to Late Miocene continental record in Spain, Earth Planet. Sci. Lett. 142 (1996) 367-380]. The long reversal in the Vargas section is now correlated to C5Br, instead of to C5Cr, on the basis of the biostratigraphical correlation of Armantes 1A to the faunas of Fuente Sierra 2 and 3 (in the Vargas section), which are situated in the basal part of the Middle Aragonian (MN5). This leads to the revised age of 16.0 Ma for the Early-Middle Aragonian (MN 4=5) boundary. Our age estimate of the MN5=6 boundary is maintained at ca. 13.75 Ma. The Vargas section is now considered to start in Chron C5Cn.2r and to end in C5Bn.1n. As a result of the revised correlation the duration of the time gap between the fossiliferous parts of Vargas and the younger Aragón section, previously estimated as ca. 1.5 Myr, is now reduced to less than 200,000 years. The tie points of the European mammal units (MN4-MN6) to the geomagnetic polarity time scale [F.F. Steininger, W.A. Berggren, D.V. Kent, R.L. Bernor, S. Sen, J. Agustí, Circum-Mediterranean Neogene (Miocene and Pliocene) marine-continental chronologic correlations of European mammal units, in: R.L Bernor, V. Fahlbusch, H.-W. Mittmann (Eds.), The Evolution of Western Eurasian Neogene Mammal Faunas, Columbia Univ. Press, New York, 1996, pp. 7-46] are evaluated. Our age estimates of the MN4=5 and MN5=6 boundaries are compatible with the new magnetostratigraphic calibration of middle Miocene mammal zones in the Swiss Molasse basin [O. Kempf, T. Bolliger, D. Kälin, B. Engesser, A. Matter, New magnetostratigraphic calibration of Early to Middle Miocene mammal biozones of the North Alpine foreland basin, in: J.-P. Aguilar, S. Legendre, J. Michaux (Eds.), Actes du Congrès BiochroM '97, Mém. Trav. E.P.H.E. 21 (1997) 547-562]. Ó 1999 Elsevier Science B.V. All rights reserved

Sex and the city: Differences in disease- and disability-free life years, and active community participation of elderly men and women in 7 cities in Latin America and the Caribbean

<p>Abstract</p> <p>Background</p> <p>The world's population is ageing, and four of the top 10 most rapidly ageing developing nations are from the region of Latin America and the Caribbean (LAC).</p> <p>Although an ageing population heralds likely increases in chronic disease, disability-related dependence, and economic burden, the societal contribution of the chronically ill or those with disability is not often measured.</p> <p>Methods</p> <p>We calculated country-specific prevalences of 'disability' (difficulty with at least one activity of daily living), 'disease' and 'co-morbidity' (presence of at least one, and at least two, of seven chronic diseases/conditions, respectively), and 'active community engagement' (using five levels of community participation, from less than weekly community contact to voluntary or paid work) in seven LAC cities. We estimated remaining life expectancy (LE) with and without disability, disease and co-morbidity, and investigated age, sex, and regional variations in disability-free LE. Finally, we modeled the association of disease, co-morbidity and disability with active community participation using an ordinal regression model, adjusted for depression.</p> <p>Results</p> <p>Overall, 77% of the LAC elderly had at least one chronic disease/condition, 44% had co-morbidity and 19% had a disability. The proportion of disability-free LE declined between the youngest (60–64 years) and the eldest (90 years and over) age-groups for both men (from 85% to 55%) and women (from 75% to 45%). Disease-free and co-morbidity-free LE, however, remained at approximately 30% and 62%, respectively, for men (20% and 48% for women), until 80–84 years of age, then increased. Only Bridgetown's participants had statistically significantly longer disability-free LE than the regional average (IRR = 1.08; 95%CI 1.05–1.10; p < 0.001). Only Santiago's participants had disability-free LE which was shorter than the regional average (IRR = 0.94; 95%CI 0.92–0.97; p < 0.001). There was 75% active community participation overall, with more women than men involved in active help (49% vs 32%, respectively) and more men involved in voluntary/paid work (46% vs 25%, respectively). There was either no, or borderline significance in the association between having one or more diseases/conditions and active community engagement for both sexes. These associations were limited by depression (odds ratio [OR] reduced by 15–17% for men, and by 8–11% for women), and only remained statistically significant in men. However, disability remained statistically significantly associated with less community engagement after adjusting for depression (OR = 0.58, 95%CI 0.49–0.69, p < 0.001 for women and OR = 0.50, 95%CI 0.47–0.65, p < 0.001 for men).</p> <p>Conclusion</p> <p>There is an increasing burden of disease and disability with older age across the LAC region. As these nations cope with resulting social and economic demands, governments and civic societies must continue to develop and maintain opportunities for community participation by this increasingly frail, but actively engaged group.</p

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

Meeting abstrac

El registro sedimentario y faunístico de las cuencas de Calatayud-Daroca y Teruel. Evolución paleoambiental y paleoclimática durante el Neógeno

Las cuencas de Calatayud-Daroca y Teruel contienen un registro sedimentario y faunístico muy completo del Neógeno continental español. En ellas están definidas las, secciones tipo del Rambliense, Aragoniense, Turoliense y Alfambriense. A su vez, el Vallesiense se encuentra muy bien representado en la parte norte de la Cuenca de Teruel, tanto litoestratigráficamente como por la amplia sucesión de faunas de vertebrados que contiene. En este trabajo se presenta un resumen y puesta al día de la información estratigráfica y sedimentológica disponible sobre las formaciones neógenas de ambas cuencas, incluyendo además datos recientes sobre el límite Aragoniense-Vallesiense en el área de Daroca-Nombrevilla y sobre el registro sedimentario de edad Plioceno en la parte más septentrional de la región de Teruel-Alfambra. Se presenta asimismo un cuadro sintético de las columnas magnetoestratigráficas elaboradas en los últimos años. Con carácter preliminar, se muestran las curvas de evolución paleoclimática (humedad/temperatura) deducibles de las asociaciones de micromamíferos presentes en una densa sucesión de yacimientos que abarcan todo el Mioceno. Las diferencias en los resultados obtenidos sobre la evolución paleoclimática de ambas cuencas son posiblemente debidas a la distinta metodología utilizada en el análisis de las asociaciones faunísticas. Por otra parte, se discuten las faltas de ajuste detectadas, al menos para algunos intervalos temporales, entre los resultados deducibles de este tipo de interpretación paleoclimática y los que se derivan del análisis sedimentológico de los depósitos.The Calatayud-Daroca and Teruel basins (NE Spain) show a very complete sedimentary and faunal record of the Spanish continental Neogene. The stratotypes for the Ramblian, Aragonian, Turolian and Alfambrian stages have been defined in these basins. Moreover, the Vallesian is well recorded especially in the northern Teruel Basin. This paper gives a state-of-the-art summary of the available information generated in the latest years by detailed sedimentological, biostratigraphical and magnetostratigraphical studies of the Neogene deposits of the basins. Recent results concerning the Aragonian-Vallesian boundary in the Daroca-Nombrevilla area are presented. A general integrated scheme of the magnetostratigraphic logs obtained from a large number of stratigraphic sections throughout the region is also included. Preliminary palaeoclimatic evolutionary curves (humidity/ temperature) are proposed for the Miocene stratigraphic record of the basins. The curves have been inferred from detailed analysis of the micromammal associations found in an extremely dense succession of mammal localities. Differences in the palaeoclimatic curves proposed for Calatayud-Daroca and Teruel may be explained by the use of different methodologies. Discrepancies between sedimentological and faunal based interpretations of the palaeoclimatic evolution of some intervals of the Miocene are discussed