119 research outputs found
Incidence of ligamentous laxity and scoliosis among the population of the United Arab Emirates
The suitability and attraction of the population of the United Arab Emirates for the study of genetic inheritance in scoliosis
The role of innovation and technology in sustaining the petroleum and petrochemical industry
Innovation and Technology go hand in hand within the petroleum and petrochemical industry. Oil price
volatility, geopolitics, and economic uncertainty, all contribute towards the continued need to innovate and
technologically advance if petroleum and petrochemical companies are to survive in this highly competitive
industry. This review paper looks at identifying the importance of innovation and technology in the
petroleum and petrochemical industry by referring to evidence in the public domain. Thereafter, the focus
shifts towards identifying both quantifiable and non-quantifiable impacts of technology and innovation
within the petroleum and petrochemical industry
Clostridium septicum infection of hepatic metastases following alcohol injection: a case report
Clostridium septicum infections are generally associated with gastrointestinal or hematologic malignancies. We report the first case of hepatic metastases infection with Clostridium septicum that followed alcohol injection of liver lesion. Clinicians should consider this possibility in patients with underlying malignancy who present with hepatic abscess, as prompt surgical drainage and empiric antibiotics may be life saving
The Qatar Biobank: background and methods
Background: The Qatar Biobank aims to collect extensive lifestyle, clinical, and biological information from up to
60,000 men and women Qatari nationals and long-term residents (individuals living in the country for ≥15 years)
aged ≥18 years (approximately one-fifth of all Qatari citizens), to follow up these same individuals over the long
term to record any subsequent disease, and hence to study the causes and progression of disease, and disease
burden, in the Qatari population.
Methods: Between the 11th-December-2012 and 20th-February-2014, 1209 participants were recruited into the pilot
study of the Qatar Biobank. At recruitment, extensive phenotype information was collected from each participant,
including information/measurements of socio-demographic factors, prevalent health conditions, diet, lifestyle,
anthropometry, body composition, bone health, cognitive function, grip strength, retinal imaging, total body dual
energy X-ray absorptiometry, and measurements of cardiovascular and respiratory function. Blood, urine, and saliva
were collected and stored for future research use. A panel of 66 clinical biomarkers was routinely measured on
fresh blood samples in all participants. Rates of recruitment are to be progressively increased in the coming period
and the recruitment base widened to achieve a cohort of consented individuals broadly representative of the
eligible Qatari population. In addition, it is planned to add additional measures in sub-samples of the cohort,
including Magnetic Resonance Imaging (MRI) of the brain, heart and abdomen.
Results: The mean time for collection of the extensive phenotypic information and biological samples from each
participant at the baseline recruitment visit was 179 min. The 1209 pilot study participants (506 men and 703
women) were aged between 28–80 years (median 39 years); 899 (74.4 %) were Qatari nationals and 310 (25.6 %)
were long-term residents. Approximately two-thirds of pilot participants were educated to graduate level or above.
Conclusions: The pilot has proven that recruitment of volunteers into the Qatar Biobank project with intensive
baseline measurements of behavioural, physical, and clinical characteristics is well accepted and logistically feasible.
Qatar Biobank will provide a powerful resource to investigate the major determinants of ill-health and well-being in
Qatar, providing valuable insights into the current and future public health burden that faces the country.Qatar Foundation for Education, Science and Community Development and the Supreme Council of Healt
Quality of Type 2 Diabetes Management in the States of The Co-Operation Council for the Arab States of the Gulf: A Systematic Review
Type 2 diabetes mellitus is a growing, worldwide public health concern. Recent growth has been particularly dramatic in the states of The Co-operation Council for the Arab States of the Gulf (GCC), and these and other developing economies are at particular risk. We aimed to systematically review the quality of control of type 2 diabetes in the GCC, and the nature and efficacy of interventions. We identified 27 published studies for review. Studies were identified by systematic database searches. Medline and Embase were searched separately (via Dialog and Ovid, respectively; 1950 to July 2010 (Medline), and 1947 to July 2010 (Embase)) on 15/07/2009. The search was updated on 08/07/2010. Terms such as diabetes mellitus, non-insulin-dependent, hyperglycemia, hypertension, hyperlipidemia and Gulf States were used. Our search also included scanning reference lists, contacting experts and hand-searching key journals. Studies were judged against pre-determined inclusion/exclusion criteria, and where suitable for inclusion, data extraction/quality assessment was achieved using a specifically-designed tool. All studies wherein glycaemic-, blood pressure- and/or lipid- control were investigated (clinical and/or process outcomes) were eligible for inclusion. No limitations on publication type, publication status, study design or language of publication were imposed. We found the extent of control to be sub-optimal and relatively poor. Assessment of the efficacy of interventions was difficult due to lack of data, but suggestive that more widespread and controlled trial of secondary prevention strategies may have beneficial outcomes. We found no record of audited implementation of primary preventative strategies and anticipate that controlled trial of such strategies would also be useful
Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications
COVID-19 complications still present a huge burden on healthcare systems and warrant predictive risk models to triage patients and inform early intervention. Here, we profile 893 plasma proteins from 50 severe and 50 mild-moderate COVID-19 patients, and 50 healthy controls, and show that 375 proteins are differentially expressed in the plasma of severe COVID-19 patients. These differentially expressed plasma proteins are implicated in the pathogenesis of COVID-19 and present targets for candidate drugs to prevent or treat severe complications. Based on the plasma proteomics and clinical lab tests, we also report a 12-plasma protein signature and a model of seven routine clinical tests that validate in an independent cohort as early risk predictors of COVID-19 severity and patient survival. The risk predictors and candidate drugs described in our study can be used and developed for personalized management of SARS-CoV-2 infected patients. 2022, The Author(s).The authors would like to thank all the patients, volunteers, and the healthcare co-workers from Allergy and Immunology Section-HMC, and Dr. Mohamed G.H. Mohamedali, Mr. Hassen Maatoug, and Mr. Ahmed Soliman from Hezm Mebairek General Hospital-HMC for developing disposable racks for samples transportation, tubes labeling, blood collection, and handling. We thank the support provided by Qatar University Biomedical Research Centre, Biosafety Level 3, and Associate Professor Hadi M. Yassine (M.Sc., Ph.D.). We also acknowledge the help of the Anti-Doping Lab-Qatar (ADLQ) and Qatar Red Crescent (QRC) for recruiting control samples. This work was supported by a grant fund from Hamad Medical Corporation (fund number MRC-05-003) and core funding from Qatar Biomedical Research Institute (QBRI).Scopu
Constructing public health policies in post crisis countries: lessons to learn from the associations between free-sugars consumption and diabetes, obesity and dental caries before, during and after sanctions in Iraq.
BACKGROUND: This article aims to provide evidence for an informed public health policy on free-sugar consumption in post-crisis countries. METHODS: Iraq was selected as a case study. A systematic search for published data on the prevalence/incidence of type-2 diabetes, overweight/obesity, dental caries and free-sugar consumption levels in Iraq was conducted using MEDLINE, the Iraqi Academic Scientific journals and relevant international organisations' websites. Comparable data before (1980-1990), during (1991-2002) and after (2003-2015) the United Nations sanctions (UNS) were included. RESULTS: Ten studies were included. Quality scores ranged between 3 and 7/8. Free-sugar consumption decreased dramatically during the UNS (from 50 to 16.3Â kg/person/year) and started increasing afterwards (24.1Â kg/person/year). Changes in type-2 diabetes, overweight/obesity and caries levels mirrored those of free-sugar consumption. Caries declined markedly during UNS and started increasing afterwards. Comparable data on diabetes and overweight/obesity were only available for the periods during and after the UNS. Both of these conditions started increasing with increased free-sugar consumption after lifting the UNS. CONCLUSIONS: There is a need to develop a public health policy in post-crisis countries to maintain the reduction in free-sugar consumption, and hence promote both general and dental health, by integrating the common risk factor approach into the social determinant framework
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Factors affecting the motivation of healthcare professionals providing care to Emiratis with type 2 diabetes
OBJECTIVE: We aimed to identify facilitators of and barriers to healthcare professionals' motivation in a diabetes centre in the United Arab Emirates (UAE).
DESIGN: A qualitative research approach was employed using semistructured interviews to assess perception of and attitudes regarding healthcare professionals' motivation in providing good quality diabetes care.
SETTING: A diabetes centre located in Abu-Dhabi, UAE.
PARTICIPANTS: Healthcare professionals including specialist physicians, dieticians, podiatrists, health educators and nurses were recruited through purposive sampling.
MAIN OUTCOME MEASURES: After data collection, the audiotaped interviews were transcribed verbatim and subjected to content analysis.
RESULTS: Nine semistructured interviews were conducted with healthcare professionals of various professional backgrounds. Important facilitators and barriers related to patient, professional, organization and cultural factors were identified. Barriers that related to heavy workload, disjointed care, lack of patient compliance and awareness, and cultural beliefs and attitudes about diabetes were common. Key facilitators included the patient's role in achieving therapeutic outcomes as well as compliance, cooperation and communication.
CONCLUSION: This qualitative study provides some unique insights about factors affecting healthcare professionals' motivation in providing good quality care. To improve the motivation of healthcare professionals in the management of diabetes and therefore the quality of diabetes care, several steps are needed. Importantly, the role of primary care should be reinforced and strengthened regarding the management of type 2 diabetes mellitus, privacy of the consultation time should be highly protected and regulated, and awareness of the Emirate culture and its impact on health should be disseminated to the healthcare professionals providing care to Emirates with diabetes. Also, greater emphasis should be placed on educating Emiratis with diabetes on, and involving them in, the management of their condition
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