A commonly misdiagnosed rare pulmonary disease: Idiopathic pleuroparenchymal fibroelastosis

Awareness among clinicians about Idiopathic pleuroparenchymal fibroelastosis (PPFE) is lacking and by the time patients are diagnosed with it, they were seen by multiple physicians and misdiagnosed multiple times. It is a rare condition that is characterized by fibrosis of the pleura and subpleural lung parenchyma, predominantly affecting the upper lobes. Most common cause of fibrosis in other processes is collagen predominant but in PPFE fibrosis is usually caused by elastic fibers. Verhoeff-Van Gieson stain from lung biopsies in patients who presented with fibrosis in the upper pleural and parenchymal areas will help in establishing the diagnosis by demonstrating the elastic fibers. We also need to rule out the possibility of other lung parenchymal conditions like usual interstitial pneumonia, nonspecific interstitial pneumonitis, pulmonary apical cap etc. We have presented a case report on PPFE to bring attention to clinicians so that patients are diagnosed early

Cryptic Eimeria genotypes are common across the southern but not northern hemisphere

The phylum Apicomplexa includes parasites of medical, zoonotic and veterinary significance. Understanding the global distribution and genetic diversity of these protozoa is of fundamental importance for efficient, robust and long-lasting methods of control. Eimeria spp. cause intestinal coccidiosis in all major livestock animals and are the most important parasites of domestic chickens in terms of both economic impact and animal welfare. Despite having significant negative impacts on the efficiency of food production, many fundamental questions relating to the global distribution and genetic variation of Eimeria spp. remain largely unanswered. Here, we provide the broadest map yet of Eimeria occurrence for domestic chickens, confirming that all the known species (Eimeria acervulina, Eimeria brunetti, Eimeria maxima, Eimeria mitis, Eimeria necatrix, Eimeria praecox, Eimeria tenella) are present in all six continents where chickens are found (including 21 countries). Analysis of 248 internal transcribed spacer sequences derived from 17 countries provided evidence of possible allopatric diversity for species such as E. tenella (FST values ⩽0.34) but not E. acervulina and E. mitis, and highlighted a trend towards widespread genetic variance. We found that three genetic variants described previously only in Australia and southern Africa (operational taxonomic units x, y and z) have a wide distribution across the southern, but not the northern hemisphere. While the drivers for such a polarised distribution of these operational taxonomic unit genotypes remains unclear, the occurrence of genetically variant Eimeria may pose a risk to food security and animal welfare in Europe and North America should these parasites spread to the northern hemisphere

Notes for genera: basal clades of Fungi (including Aphelidiomycota, Basidiobolomycota, Blastocladiomycota, Calcarisporiellomycota, Caulochytriomycota, Chytridiomycota, Entomophthoromycota, Glomeromycota, Kickxellomycota, Monoblepharomycota, Mortierellomycota, Mucoromycota, Neocallimastigomycota, Olpidiomycota, Rozellomycota and Zoopagomycota)

Compared to the higher fungi (Dikarya), taxonomic and evolutionary studies on the basal clades of fungi are fewer in number. Thus, the generic boundaries and higher ranks in the basal clades of fungi are poorly known. Recent DNA based taxonomic studies have provided reliable and accurate information. It is therefore necessary to compile all available information since basal clades genera lack updated checklists or outlines. Recently, Tedersoo et al. (MycoKeys 13:1--20, 2016) accepted Aphelidiomycota and Rozellomycota in Fungal clade. Thus, we regard both these phyla as members in Kingdom Fungi. We accept 16 phyla in basal clades viz. Aphelidiomycota, Basidiobolomycota, Blastocladiomycota, Calcarisporiellomycota, Caulochytriomycota, Chytridiomycota, Entomophthoromycota, Glomeromycota, Kickxellomycota, Monoblepharomycota, Mortierellomycota, Mucoromycota, Neocallimastigomycota, Olpidiomycota, Rozellomycota and Zoopagomycota. Thus, 611 genera in 153 families, 43 orders and 18 classes are provided with details of classification, synonyms, life modes, distribution, recent literature and genomic data. Moreover, Catenariaceae Couch is proposed to be conserved, Cladochytriales Mozl.-Standr. is emended and the family Nephridiophagaceae is introduced

Modelling the Leakage Rate and Reduction Using Minimum Night Flow Analysis in an Intermittent Supply System

A significant portion of the water supplied to people doesn’t reach its valid users but instead leaks out of the distribution network, causing water wastage, revenue loss and contamination risks. This paper analyses the leakage rate, leakage components and leakage reduction potential. A minimum night flow (MNF) analysis was carried out on a district metered area (DMA) in an intermittent supply system in Zarqa, Jordan. Leakage was modelled and leakage reduction policies were analysed. Results show that MNF occurs at night or during day time depending on the water levels in customer tanks, implying that one-day MNF analysis cannot be carried out in intermittent supplies and the estimation of the legitimate consumption during MNF is more influential. The potential water savings of the different leakage reduction measures (pressure management; leakage detection; response time minimization) are separately analysed in the existing models in the literature, leading to significant overestimation of the total leakage reduction potential, while these measures are influencing each other. Pressure reduction lowers the failure frequencies but limits the potential of leakage detection surveys, as leaks will become harder to hear and detect. Investigating the inter-dependency relations of these measures is therefore essential for reasonable leakage reduction modelling and planning

A quarantine protocol against red palm weevil Rhynchophorus Ferrugineus (Olivier) (Coleptera: Curculiondae) in date palm

The red palm weevil (RPW) Rhynchophorus ferrugineus (Olivier), (Coleptera: Curculiondae) is a key pest of date palm in the Middle East. This weevil is currently being reported from over 50% of the date growing countries of the world. The date palm Phoenix dactylifera cropped area in the Middle East, has significantly increased during the last two decades where date palm is mainly propagated through offshoots. The red palm weevil larvae are often found in the offshoots, resulting in the spread of the pest and also its re-inoculation where RPW is already controlled. Currently, there are no quarantine protocols to ensure that date palm offshoots which are transported for planting, are free of RPW larvae. In this study, date palm offshoots were sprayed while still attached to the mother palm and also dipped separately with Fipronil 3.5% (Thripguard 35 SCTM) and Imidacloprid 35% (Confidor 350 SCTM) a day after detachment from the mother palm. Fipronil and Imidacloprid were tested at 0.008 % and 0.01%, respectively. Results revealed that dipping gave complete mortality of the larvae. Dipping was significantly better than spraying since spraying resulted in only partial mortality of the larvae. It was also seen that dipping offshoots in Fipronil 0.004% and 0.002% for 30 and 60 min, respectively, resulted in 100% mortality of the larvae tested. Further, toxicity studies resulted in complete mortality of larvae and adults that were exposed to offshoot tissue that was dipped in Fipronil at the above concentrations. For this reason, it is recommended to dip date palm offshoots in 0.004% Fipronil for 30 min before transporting to ensure complete mortality of the hidden larval stages, if any and complete certification and transport of the treated offshoots to the new planting site within 72 h of treatment