8-Ethyl-2-hydr­oxy-2-methyl-4-morpholinoethyl-1-thia-4-aza­spiro­[4.5]decan-3-one

Mol­ecules of the title spiro­[4.5]decane derivative, C17H30N2O3S, are linked by paired O—H⋯N hydrogen bonds into centrosymmetric R 2 2(16) dimers and these dimers are linked into a three-dimensional framework structure by C—H⋯O interactions

Diethyl 5-[(2-hydr­oxy-1-naphth­yl)methyl­ideneamino]-3-methyl­thio­phene-2,4-dicarboxyl­ate

In the title compound, C22H21NO5S, the 2-naphthol group and the thio­phene ring are almost coplanar, with a dihedral angle of 5.75 (7)°. The structure is stabilized by intra­molecular O—H⋯O, O—H⋯N and C—H⋯S, and inter­molecular C—H⋯O hydrogen-bonding inter­actions

2-{2-[4-(4-Fluoro­phen­yl)piperazin-1-yl]-2-oxoeth­yl}-6-(morpholin-4-yl)-4-phenyl­pyridazin-3(2H)-one

In the title compound, C26H28FN5O3, the morpholine ring adopts a chair conformation. The piperazine ring is puckered [Q T = 0.5437 (15) Å, θ = 8.89 (15) and ϕ = 357.2 (11)°]. The 1,6-dihydro­pyridazine ring makes dihedral angles of 28.03 (7) and 77.46 (7)° with the phenyl and benzene rings, respectively. In the crystal, mol­ecules are linked along the c axis by C—H⋯O inter­actions and are flattened parallel to the ac plane. C–H⋯π inter­actions also contribute to the stability of the structure

N′-[(E)-2-Hy­droxy-5-meth­oxy­benzyl­idene]pyridine-4-carbohydrazide

In the title compound, C14H13N3O3, the dihedral angle between the pyridine and benzene rings is 15.17 (18)°. The torsion angle of the –C=N—N—C– system between two aromatic rings is −167.1 (3)°. Intra­molecular O—H⋯N hydrogen bonding generates S(6) rings. In the crystal structure, neighbouring mol­ecules are linked together along the c axis by weak inter­molecular C—H⋯O and N—H⋯O hydrogen bonds, generating R 1 2(6) ring motifs

3-Anilinomethyl-5-chloro-1,3-­benzoxazol-2(3H)-one

In the title compound, C14H11ClN2O2, the 2,3-dihydro-1,3-benzoxazole ring system is essentially planar [maximum deviation = 0.009 (2) Å] and makes a dihedral angle of 79.15 (7)° with the phenyl ring. Inter­molecular N—H⋯O and weak C—H⋯Cl hydrogen bonds occur in the crystal structure

5-Bromo-2-hy­droxy­benzaldehyde thio­semicarbazone

The mol­ecule of the title compound, C8H8BrN3OS, is close to being planar, with maximum deviations of −0.127 (3) and 0.135 (5) Å for the N atoms of the –NH– and NH2– groups, respectively. Intra­molecular N—H⋯N and O—H⋯N hydrogen bonds to the same acceptor N atom generate S(5) and S(6) ring motifs. In the crystal structure, mol­ecules are connected into [010] chains by pairs of N—H⋯S hydrogen bonds with R 2 2(8) graph-set motifs. The crystal used for data collection was found to be an inversion twin

5-Chloro-2-hy­droxy­benzaldehyde thio­semicarbazone

In the title compound, C8H8ClN3OS, the whole mol­ecule assumes a planar structure, with an r.m.s. deviation of 0.108 (2) Å, and an intra­molecular O—H⋯N hydrogen bond generates and S(6) and ring motif. In the crystal structure, each of two pairs of inter­molecular N—H⋯S hydrogen bonds connects two mol­ecules, forming inversion dimers with R 2 2(8) motifs

Methyl 2-amino-5-bromo­benzoate

In the title compound, C8H8BrNO2, the dihedral angle between the aromatic ring and the methyl acetate side chain is 5.73 (12)°. The mol­ecular conformation is stabilized by an intra­molecular N—H⋯O hydrogen bond, generating an S(6) ring. In the crystal, mol­ecules are connected by N—H⋯O inter­actions, generating zigzag chains running along the b-axis direction

1-(4-Meth­oxy­phen­yl)-4-(3-nitro­phen­yl)-3-phen­oxy­azetidin-2-one

In the title compound, C22H18N2O5, the four-membered β-lactam ring is nearly planar, with a maximum deviation of 0.023 (2) Å for the N atom, and has long C—C distances of 1.525 (5) and 1.571 (5) Å. The mean plane of this group makes dihedral angles of 11.61 (19), 74.5 (2) and 72.3 (2)° with three aromatic rings. An intra­molecular C—H⋯O hydrogen bond occurs. The packing of the mol­ecules in the crystal structure is governed mainly by inter­molecular C—H⋯O hydrogen-bonding and C—H⋯π stacking inter­actions. Furthermore, a π–π inter­action [centroid–centroid distance = 3.6129 (19) Å] helps to stabilize the crystal structure