1,239 research outputs found
8-Ethyl-2-hydroxy-2-methyl-4-morpholinoethyl-1-thia-4-azaspiro[4.5]decan-3-one
Molecules of the title spiro[4.5]decane derivative, C17H30N2O3S, are linked by paired O—H⋯N hydrogen bonds into centrosymmetric R
2
2(16) dimers and these dimers are linked into a three-dimensional framework structure by C—H⋯O interactions
Diethyl 5-[(2-hydroxy-1-naphthyl)methylideneamino]-3-methylthiophene-2,4-dicarboxylate
In the title compound, C22H21NO5S, the 2-naphthol group and the thiophene ring are almost coplanar, with a dihedral angle of 5.75 (7)°. The structure is stabilized by intramolecular O—H⋯O, O—H⋯N and C—H⋯S, and intermolecular C—H⋯O hydrogen-bonding interactions
2-{2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl}-6-(morpholin-4-yl)-4-phenylpyridazin-3(2H)-one
In the title compound, C26H28FN5O3, the morpholine ring adopts a chair conformation. The piperazine ring is puckered [Q
T = 0.5437 (15) Å, θ = 8.89 (15) and ϕ = 357.2 (11)°]. The 1,6-dihydropyridazine ring makes dihedral angles of 28.03 (7) and 77.46 (7)° with the phenyl and benzene rings, respectively. In the crystal, molecules are linked along the c axis by C—H⋯O interactions and are flattened parallel to the ac plane. C–H⋯π interactions also contribute to the stability of the structure
N′-[(E)-2-Hydroxy-5-methoxybenzylidene]pyridine-4-carbohydrazide
In the title compound, C14H13N3O3, the dihedral angle between the pyridine and benzene rings is 15.17 (18)°. The torsion angle of the –C=N—N—C– system between two aromatic rings is −167.1 (3)°. Intramolecular O—H⋯N hydrogen bonding generates S(6) rings. In the crystal structure, neighbouring molecules are linked together along the c axis by weak intermolecular C—H⋯O and N—H⋯O hydrogen bonds, generating R
1
2(6) ring motifs
3-Anilinomethyl-5-chloro-1,3-benzoxazol-2(3H)-one
In the title compound, C14H11ClN2O2, the 2,3-dihydro-1,3-benzoxazole ring system is essentially planar [maximum deviation = 0.009 (2) Å] and makes a dihedral angle of 79.15 (7)° with the phenyl ring. Intermolecular N—H⋯O and weak C—H⋯Cl hydrogen bonds occur in the crystal structure
5-Bromo-2-hydroxybenzaldehyde thiosemicarbazone
The molecule of the title compound, C8H8BrN3OS, is close to being planar, with maximum deviations of −0.127 (3) and 0.135 (5) Å for the N atoms of the –NH– and NH2– groups, respectively. Intramolecular N—H⋯N and O—H⋯N hydrogen bonds to the same acceptor N atom generate S(5) and S(6) ring motifs. In the crystal structure, molecules are connected into [010] chains by pairs of N—H⋯S hydrogen bonds with R
2
2(8) graph-set motifs. The crystal used for data collection was found to be an inversion twin
5-Chloro-2-hydroxybenzaldehyde thiosemicarbazone
In the title compound, C8H8ClN3OS, the whole molecule assumes a planar structure, with an r.m.s. deviation of 0.108 (2) Å, and an intramolecular O—H⋯N hydrogen bond generates and S(6) and ring motif. In the crystal structure, each of two pairs of intermolecular N—H⋯S hydrogen bonds connects two molecules, forming inversion dimers with R
2
2(8) motifs
Methyl 2-amino-5-bromobenzoate
In the title compound, C8H8BrNO2, the dihedral angle between the aromatic ring and the methyl acetate side chain is 5.73 (12)°. The molecular conformation is stabilized by an intramolecular N—H⋯O hydrogen bond, generating an S(6) ring. In the crystal, molecules are connected by N—H⋯O interactions, generating zigzag chains running along the b-axis direction
1-(4-Methoxyphenyl)-4-(3-nitrophenyl)-3-phenoxyazetidin-2-one
In the title compound, C22H18N2O5, the four-membered β-lactam ring is nearly planar, with a maximum deviation of 0.023 (2) Å for the N atom, and has long C—C distances of 1.525 (5) and 1.571 (5) Å. The mean plane of this group makes dihedral angles of 11.61 (19), 74.5 (2) and 72.3 (2)° with three aromatic rings. An intramolecular C—H⋯O hydrogen bond occurs. The packing of the molecules in the crystal structure is governed mainly by intermolecular C—H⋯O hydrogen-bonding and C—H⋯π stacking interactions. Furthermore, a π–π interaction [centroid–centroid distance = 3.6129 (19) Å] helps to stabilize the crystal structure
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