6 research outputs found
Iron Behaving Badly: Inappropriate Iron Chelation as a Major Contributor to the Aetiology of Vascular and Other Progressive Inflammatory and Degenerative Diseases
- Author
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- The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group
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- ZZ Chong
- Publication venue
- Publication date
- 09/08/2008
- Field of study
The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular "reactive oxygen species" (ROSs)
can exhibit a number of biological effects, they are not of themselves
excessively reactive and thus they are not especially damaging at physiological
concentrations. However, their reactions with poorly liganded iron species can
lead to the catalytic production of the very reactive and dangerous hydroxyl
radical, which is exceptionally damaging, and a major cause of chronic
inflammation. We review the considerable and wide-ranging evidence for the
involvement of this combination of (su)peroxide and poorly liganded iron in a
large number of physiological and indeed pathological processes and
inflammatory disorders, especially those involving the progressive degradation
of cellular and organismal performance. These diseases share a great many
similarities and thus might be considered to have a common cause (i.e.
iron-catalysed free radical and especially hydroxyl radical generation). The
studies reviewed include those focused on a series of cardiovascular, metabolic
and neurological diseases, where iron can be found at the sites of plaques and
lesions, as well as studies showing the significance of iron to aging and
longevity. The effective chelation of iron by natural or synthetic ligands is
thus of major physiological (and potentially therapeutic) importance. As
systems properties, we need to recognise that physiological observables have
multiple molecular causes, and studying them in isolation leads to inconsistent
patterns of apparent causality when it is the simultaneous combination of
multiple factors that is responsible. This explains, for instance, the
decidedly mixed effects of antioxidants that have been observed, etc...Comment: 159 pages, including 9 Figs and 2184 reference
Reviewing the use of resilience concepts in forest sciences
- Author
- A Borkenhagen
- A Bottero
- A Bottero
- A Dănescu
- A Fernandez-Manso
- A García-Romero
- A Gazol
- A Gazol
- A Gazol
- A Gazol
- A Herrero
- A Karavani
- A Knudby
- A Martínez-Yrízar
- A Nightingale
- A Príncipe
- A Rais
- A Saxena
- A Schaffhauser
- A Sharma
- AC Newton
- AE Lebrija-trejos
- AE Quinlan
- AEM Waltz
- AJ Clason
- AJ Kerkhoff
- AJ Larson
- AK Rydgren
- AU Mallik
- AW D’Amato
- B Ayala-Orozco
- B Buma
- B Buma
- B Burkhard
- B Di Mauro
- B Sakschewski
- B Walker
- B Wolfslehner
- BF Jacobs
- BM Spears
- C Bahamondez
- C Bone
- C Chompuchan
- C Folke
- C Kelly
- C Lyon
- C Messier
- C Messier
- C Temperli
- C Xu
- C Zang
- CA Doughty
- CA Estevo
- CC Dymond
- CC Dymond
- CD Thomas
- CH Wu
- CM Arthur
- CPO Reyer
- CR Drever
- CR Halpin
- CR Nitschke
- CS Holling
- CS Stevens-Rumann
- D Craven
- D Diaconu
- D Helman
- D Lawrence
- D Rivest
- D Stampoulis
- D Thom
- DA Wardle
- DC Zemp
- DJ Churchill
- DJ Wilson
- DM Alongi
- DM Olson
- E Andivia
- E Andivia
- E Cantarello
- E Granda
- E Kaarlejärvi
- E Stuart-Haëntjens
- EAD Bowditch
- ED Brown
- EF Viglizzo
- EK Zenner
- F Candan
- F DeClerck
- F Girard
- F Lloret
- F Lloret
- F Lloret
- F Müller
- FS Chapin
- FS Chapin
- FS Chapin
- FS Chapin
- G Carnwath
- G Chaer
- G Derroire
- G Grassi
- G Matusick
- G Reyes
- G Verstraeten
- GE Ponce Campos
- GM Malinga
- H Bruelheide
- H Ding
- H Guimarães
- H Pretzsch
- H Yan
- HCP Brown
- HL Ballard
- HR Heinimann
- I Abbott
- I Bernetti
- I Pilaš
- I Vanha-Majamaa
- IA Van De Leemput
- ID Thompson
- IF Creed
- IM Pérez-Ramos
- J Dörner
- J Julio Camarero
- J Kunz
- J Madrigal-González
- J Martínez-Vilalta
- J Park
- J Philp
- J Singer
- J Verbesselt
- J Weichselgartner
- JA Ludwig
- JA Sohn
- JC Torrico
- JD Bates
- JD Hale
- JF Johnstone
- JF Johnstone
- JH Bihn
- JM Daniels
- JM García-López
- JN Long
- JP George
- JP Roccaforte
- JS Halofsky
- JT Ibarra
- JV Moris
- JW Smith
- K Akamani
- K Akamani
- K Akamani
- K Brown
- K Heer
- K Jacquet
- K Magis
- KE Selwood
- KJ Puettmann
- KL O’Hara
- KP McLaren
- KS Summerville
- L Fuller
- L Lopez-Toledo
- L Marqués
- L Olsson
- L Poorter
- L Rist
- L Salvati
- L Xu
- LE Calderon-Aguilera
- LES Cole
- LH Gunderson
- LJS Anjos
- LM de Souza
- LR Tambosi
- M Arianoutsou
- M Bernhardt-Römermann
- M Cote
- M Dodd
- M Dynesius
- M Hanewinkel
- M Hirota
- M Kim
- M Lindner
- M Magruder
- M Merlin
- M Moretti
- M Moretti
- M Savage
- M Scheffer
- M Scheffer
- M Shinoda
- M Silva Pedro
- M Sánchez-Pinillos
- MA Windmuller-Campione
- MB Bialecki
- MB Winter
- MG Turner
- MH Hancock
- MJ Broncano
- MJ Duveneck
- MJ O’Brien
- MJ Spasojevic
- MP Jarzebski
- MR Willig
- MS Lucash
- MT Curzon
- N Hoffmann
- N Van Vierssen
- P Magnuszewski
- P Roovers
- PJ Balint
- PJ Mitchell
- PK Wallem
- R Bhaskar
- R DasGupta
- R Díaz-Delgado
- R Montúfar
- R Seidl
- R Seidl
- R Seidl
- R Sánchez-Salguero
- R Trouvé
- R Yousefpour
- RC Team
- RJ DeRose
- RM Navarro-Cerrillo
- RS Wittkuhn
- RT Belote
- RT Fahey
- RT Fahey
- S Aikio
- S Carpenter
- S González-De Vega
- S Hosseini
- S Moser
- S Roostaie
- S Royer-Tardif
- S Taeger
- SA Wakelin
- SL Pimm
- SM Carrillo-Saucedo
- SM Hood
- SM Reis
- SR Abella
- T Kipfer
- T Na-U-Dom
- T Schoennagel
- T Wu
- TC Lin
- TCC Leão
- TG Knoot
- TJ Curran
- TL Keyser
- TM Danielson
- U Schirpke
- V Acuña
- V Proença
- V Vitali
- VJ Jaramillo
- VM Toledo
- VS Malika
- W Huang
- W Steffen
- W Thuiller
- WA Reiners
- WL Baker
- X Arnan
- X Serra-Maluquer
- XJ Walker
- Y Xu
- Á Rubio-Cuadrado
- Á Rubio-Cuadrado
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 11/02/2020
- Field of study
Purpose of the review Resilience is a key concept to deal with an uncertain future in forestry. In recent years, it has received increasing attention from both research and practice. However, a common understanding of what resilience means in a forestry context, and how to operationalise it is lacking. Here, we conducted a systematic review of the recent forest science literature on resilience in the forestry context, synthesising how resilience is defined and assessed.
Recent findings Based on a detailed review of 255 studies, we analysed how the concepts of engineering resilience, ecological resilience, and social-ecological resilience are used in forest sciences. A clear majority of the studies applied the concept of engineering resilience, quantifying resilience as the recovery time after a disturbance. The two most used indicators for engineering resilience were basal area increment and vegetation cover, whereas ecological
resilience studies frequently focus on vegetation cover and tree density. In contrast, important social-ecological resilience indicators used in the literature are socio-economic diversity and stock of natural resources. In the context of global change, we expected an increase in studies adopting the more holistic social-ecological resilience concept, but this was not the observed trend. Summary Our analysis points to the nestedness of these three resilience concepts, suggesting that they are complementary rather than contradictory. It also means that the variety of resilience approaches does not need to be an obstacle for operationalisation of the concept. We provide guidance for choosing the most suitable resilience concept and indicators based on the management, disturbance and application context
Relative importance of caries risk factors in Finnish mentally retarded children
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Attenuation of Streptozotocin-Induced Lipid Profile Anomalies in the Heart, Brain, and mRNA Expression of HMG-CoA Reductase by Diosgenin in Rats
- Author
- A Satheesh
- A Zlatkis
- AJ Jagadeesan
- AK Tiwari
- AN Nagappa
- B Draznin
- C Folch
- CA Reasner
- Dan Li
- DB Zilversmit
- DJ Shapiro
- G Saravanan
- G Saravanan
- GC Ness
- HR Superko
- JE Braun
- K Falholt
- K Yagi
- Kexiang Liu
- KN Frayn
- L Pari
- L Pari
- M Kaleem
- N Ashokkumar
- N Pulido
- OL Erukainure
- P Fossati
- P Palsamy
- P Proks
- P Pushparaj
- PC Deedwania
- PV Anandh Babu
- R Farhad
- Rihao Xu
- RM Cohn
- S Akiyama
- S Mastan
- SH Kim
- Shuang Hao
- T Rydgren
- TH Kang
- Tiance Wang
- UPS Chauhan
- Y Kuwahara
- YMK Farag
- Zhicheng Zhu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Trampling tolerance of understorey vegetation in different hemiboreal urban forest site types in Finland
- Author
- A Arnberger
- A Thimonier
- A Tolvanen
- AK Cajander
- BG Jonsson
- C Florgård
- C Florgård
- DN Cole
- DN Cole
- DN Cole
- GM Dirkse
- H Andren
- H Hautala
- H Hiirsalmi
- Ilkka Vanha-Majamaa
- Irja Löfström
- J Chen
- J Kuusipalo
- J Kuusipalo
- J Kuusipalo
- J Littlemore
- Jari Niemelä
- JR Busby
- K Lehtilä
- K Rydgren
- KC Weathers
- L Kullman
- L Tyrväinen
- Leena Hamberg
- M Guirado
- M Malmivaara
- M Malmivaara-Lämsä
- M Nylund
- Minna Malmivaara-Lämsä
- MJ Liddle
- MJ Liddle
- P Roovers
- R Bobbink
- R Mäkipää
- R Mäkipää
- R Mäkipää
- S Kellomäki
- S Kellomäki
- S Kellomäki
- S Kellomäki
- S Lehvävirta
- S Lehvävirta
- S Zerbe
- T Ahti
- T Kuuluvainen
- T Lahti
- T Sievänen
- T Tonteri
- T Tonteri
- TV Callaghan
- V Gundersen
- WE Hammitt
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The Effect of Pre-cooling the Injection Site on Pediatric Pain Perception during the Administration of Local Anesthesia
- Author
- Aberer W.
- Abramson DI Chu LS, Tuck S Jr, Lee SW, Richardson G, Levin M.
- Bartfield JM Crisafulli KM, Raccio-Robak N, Salluzzo RF.
- Brandner B Munro B, Bromby LM, Hetreed M.
- Brandner B Munro B, Bromby LM, Hetreed M.
- Brandsson S Rydgren B, Hedner T, Eriksson BI, Lundin O, Swärd L, Karlsson J.
- Broussard LA Broussard AK, Pittman TS, Lirette DK.
- Chan HH Lam LK, Wong DS, Wei WI.
- Colaric KB Overton DT, Moore K.
- Courtney DJ Agrawal S, Revington PJ.
- Daniel DM Stone ML, Arendt DL.
- Ernst E Fialka V.
- Fiset L Milgrom P, Weinstein P, Getz T, Glassman P.
- Fitton AR Ragbir M, Milling MA.
- Goel S Chang B, Bhan K, El-Hindy N, Kolli S.
- Grassick P.
- Halar EM DeLisa JA, Brozovich FV.
- Harbert H.
- Hubbard TJ Denegar CR.
- Kuwahara RT Skinner RB.
- Lacour M Le Coultre C.
- Leff DR Nortley M, Van Dang, Bhutiani RP.
- Marks I.
- Masters JE.
- Mathewson RJ Primosch RE.
- McMaster WC.
- McMaster WC.
- Meeusen R Lievens P.
- Meeusen R Lievens P.
- Meeusen R Lievens P.
- Nuttall NM Bradnock G, White D, Morris J, Nunn J.
- O'Brien L Taddio A, Lyszkiewicz DA, Koren G.
- Ohkoshi Y Ohkoshi M, Nagasaki S.
- Ohkoshi Y Ohkoshi M, Nagasaki S.
- Ong EL Lim NL, Koay CK.
- Orlinsky M Hudson C, Chan L, Deslauriers R.
- Ost LG.
- Ottoson D.
- Russell SC Doyle E.
- Saito N Horiuchi H, Kobayashi S, Nawata M, Takaoka K.
- Saito N Horiuchi H, Kobayashi S, Nawata M, Takaoka K.
- Scarfone RJ Jasani M, Gracely EJ.
- Touyz LZ Lamontagne P, Smith BE.
- van der Westhuijzen AJ Becker PJ, Morkel J, Roelse JA.
- Waibel KH Katial RK.
- Yoon WY Chung SP, Lee HS, Park YS.
- Younis I Bhutiani RP.
- Publication venue
- 'Jaypee Brothers Medical Publishing'
- Publication date
- Field of study