5,540 research outputs found
Adequacy Assessment of a Wind-Integrated System Using Neural Network-based Interval Predictions of Wind Power Generation and Load
In this paper, we present a modeling and simulation framework for conducting the adequacy assessment of a wind-integrated power system accounting for the associated uncertainties. A multi-perceptron artificial neural network (NN) is trained by a non-dominated sorting genetic algorithm-II (NSGA-II) to forecast point-values and prediction intervals (PIs) of the wind power and load. The output of the assessment is given in terms of point-valued and interval-valued Expected Energy Not Supplied (EENS). We consider different scenarios of wind power and load levels, to explore the influence of the uncertainty in wind and load predictions on the estimation of system adequacy
NSGA-II-trained neural network approach to the estimation of prediction intervals of scale deposition rate in oil & gas equipment
International audienceScale deposition can damage equipment in the oil & gas production industry. Hence, the reliable and accurate prediction of the scale deposition rate is critical for production availability. In this study, we consider the problem of predicting the scale deposition rate, providing an indication of the associated prediction uncertainty. We tackle the problem using an empirical modeling approach, based on experimental data. Specifically, we implement a multi-objective genetic algorithm (namely, non-dominated sorting genetic algorithm-II (NSGA-II)) to train a neural network (NN) (i.e. to find its parameters, that is its weights and biases) to provide the prediction intervals (PIs) of the scale deposition rate. The PIs are optimized both in terms of accuracy (coverage probability) and dimension (width). We perform k-fold cross-validation to guide the choice of the NN structure (i.e. the number of hidden neurons). We use hypervolume indicator metric to evaluate the Pareto fronts in the validation step. A case study is considered, with regards to a set of experimental observations: the NSGA-II-trained neural network is shown capable of providing PIs with both high coverage and small width
A comprehensive study of the open cluster NGC 6866
We present CCD  photometry of the field of the open cluster NGC 6866.
Structural parameters of the cluster are determined utilizing the stellar
density profile of the stars in the field. We calculate the probabilities of
the stars being a physical member of the cluster using their astrometric data
and perform further analyses using only the most probable members. The
reddening and metallicity of the cluster were determined by independent
methods. The LAMOST spectra and the ultraviolet excess of the F and G type
main-sequence stars in the cluster indicate that the metallicity of the cluster
is about the solar value. We estimated the reddening 
mag using the  vs  two-colour diagram. The distance modula, the
distance and the age of NGC 6866 were derived as  mag,
 pc and  Myr, respectively, by fitting
colour-magnitude diagrams of the cluster with the PARSEC isochrones. The
Galactic orbit of NGC 6866 indicates that the cluster is orbiting in a slightly
eccentric orbit with . The mass function slope  was
derived by using the most probable members of the cluster.Comment: 14 pages, including 16 figures and 7 tables, accepted for publication
  in MNRAS. Table 4 in the manuscript will be published electronicall
B-> D* zero-recoil formfactor and the heavy quark expansion in QCD: a systematic study
We present a QCD analysis of heavy quark mesons focussing on the B -> D*
formfactor at zero recoil, F_D*(1). An advanced treatment of the perturbative
corrections in the Wilsonian approach is presented. We estimate the
higher-order power corrections to the OPE sum rule and describe a refined
analysis of the nonresonant continuum contribution. In the framework of a
model-independent approach, we show that the inelastic contribution in the
phenomenological part of the OPE is related to the mQ-dependence of the
hyperfine splitting and conclude that the former is large, lowering the
prediction for F_D*(1) down to about 0.86. This likewise implies an enhanced
yield of radial and D-wave charm excitations in semileptonic B decays and
alleviates the problem with the inclusive yield of the wide excited states. We
also apply the approach to the expectation values of dimension 7 and 8 local
operators and to a few other issues in the heavy quark expansion.Comment: 70 pages, 13 figure
SPH Simulations of Negative (Nodal) Superhumps: A Parametric Study
Negative superhumps in cataclysmic variable systems result when the accretion
disc is tilted with respect to the orbital plane. The line of nodes of the
tilted disc precesses slowly in the retrograde direction, resulting in a
photometric signal with a period slightly less than the orbital period. We use
the method of smoothed particle hydrodynamics to simulate a series of models of
differing mass ratio and effective viscosity to determine the retrograde
precession period and superhump period deficit  as a function of
system mass ratio . We tabulate our results and present fits to both
 and  versus , as well as compare the
numerical results with those compiled from the literature of negative superhump
observations. One surprising is that while we find negative superhumps most
clearly in simulations with an accretion stream present, we also find evidence
for negative superhumps in simulations in which we shut off the mass transfer
stream completely, indicating that the origin of the photometric signal is more
complicated than previously believed.Comment: 14 pages, 15 figures. Accepted for publication in MNRA
Accretion Discs with an Inner Spiral Density Wave
In Montgomery (2009a), we show that accretion discs in binary systems could
retrogradely precess by tidal torques like the Moon and the Sun on a tilted,
spinning, non-spherical Earth. In addition, we show that the state of matter
and the geometrical shape of the celestial object could significantly affect
the precessional value. For example, a Cataclysmic Variable (CV) Dwarf Novae
(DN) non-magnetic system that shows negative superhumps in its light curve can
be described by a retrogradely precessing, differentially rotating, tilted
disc. Because the disc is a fluid and because the gas stream overflows the
tilted disc and particles can migrate into inner disc annuli, coupled to the
disc could be a retrogradely precessing inner ring that is located near the
innermost annuli of the disc. However, numerical simulations by Bisikalo et al.
(2003, 2004) and this work show that an inner spiral density wave can be
generated instead of an inner ring. Therefore, we show that retrograde
precession in non-magnetic, spinning, tilted CV DN systems can equally be
described by a retrogradely precessing and differentially rotating disc with an
attached retrogradely precessing inner spiral density wave so long as the wave
appears at the same radius as the ring and within the plane of the tilted disc.
We find that the theoretical results generated in this work agree well with the
theoretical results presented in Montgomery (2009a) and thus with the numerical
simulations and select CV DN systems in Montgomery (2009b) that may have a main
sequence secondary. Therefore, pressure effects do need to be considered in CV
DN systems that exhibit negative superhumps if the accretion discs are tilted
and have an inner spiral density wave that is in the plane of the disc
Discovery (theoretical prediction and experimental observation) of a large-gap topological-insulator class with spin-polarized single-Dirac-cone on the surface
Recent theories and experiments have suggested that strong spin-orbit
coupling effects in certain band insulators can give rise to a new phase of
quantum matter, the so-called topological insulator, which can show macroscopic
entanglement effects. Such systems feature two-dimensional surface states whose
electrodynamic properties are described not by the conventional Maxwell
equations but rather by an attached axion field, originally proposed to
describe strongly interacting particles. It has been proposed that a
topological insulator with a single spin-textured Dirac cone interfaced with a
superconductor can form the most elementary unit for performing fault-tolerant
quantum computation. Here we present an angle-resolved photoemission
spectroscopy study and first-principle theoretical calculation-predictions that
reveal the first observation of such a topological state of matter featuring a
single-surface-Dirac-cone realized in the naturally occurring BiSe
class of materials. Our results, supported by our theoretical predictions and
calculations, demonstrate that undoped compound of this class of materials can
serve as the parent matrix compound for the long-sought topological device
where in-plane surface carrier transport would have a purely quantum
topological origin. Our study further suggests that the undoped compound
reached via n-to-p doping should show topological transport phenomena even at
room temperature.Comment: 3 Figures, 18 pages, Submitted to NATURE PHYSICS in December 200
Sensing electric fields using single diamond spins
The ability to sensitively detect charges under ambient conditions would be a
fascinating new tool benefitting a wide range of researchers across
disciplines. However, most current techniques are limited to low-temperature
methods like single-electron transistors (SET), single-electron electrostatic
force microscopy and scanning tunnelling microscopy. Here we open up a new
quantum metrology technique demonstrating precision electric field measurement
using a single nitrogen-vacancy defect centre(NV) spin in diamond. An AC
electric field sensitivity reaching ~ 140V/cm/\surd Hz has been achieved. This
corresponds to the electric field produced by a single elementary charge
located at a distance of ~ 150 nm from our spin sensor with averaging for one
second. By careful analysis of the electronic structure of the defect centre,
we show how an applied magnetic field influences the electric field sensing
properties. By this we demonstrate that diamond defect centre spins can be
switched between electric and magnetic field sensing modes and identify
suitable parameter ranges for both detector schemes. By combining magnetic and
electric field sensitivity, nanoscale detection and ambient operation our study
opens up new frontiers in imaging and sensing applications ranging from
material science to bioimaging
The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.
p53 and its major E3 ligase Mdm2 are both ubiquitinated and targeted to the proteasome for degradation. Despite the importance of this in regulating the p53 pathway, little is known about the mechanisms of proteasomal recognition of ubiquitinated p53 and Mdm2. In this study, we show that knockdown of the proteasomal ubiquitin receptor S5a/PSMD4/Rpn10 inhibits p53 protein degradation and results in the accumulation of ubiquitinated p53. Overexpression of a dominant-negative deletion of S5a lacking its ubiquitin-interacting motifs (UIM)s, but which can be incorporated into the proteasome, also causes the stabilization of p53. Furthermore, small-interferring RNA (siRNA) rescue experiments confirm that the UIMs of S5a are required for the maintenance of low p53 levels. These observations indicate that S5a participates in the recognition of ubiquitinated p53 by the proteasome. In contrast, targeting S5a has no effect on the rate of degradation of Mdm2, indicating that proteasomal recognition of Mdm2 can be mediated by an S5a-independent pathway. S5a knockdown results in an increase in the transcriptional activity of p53. The selective stabilization of p53 and not Mdm2 provides a mechanism for p53 activation. Depletion of S5a causes a p53-dependent decrease in cell proliferation, demonstrating that p53 can have a dominant role in the response to targeting S5a. This study provides evidence for alternative pathways of proteasomal recognition of p53 and Mdm2. Differences in recognition by the proteasome could provide a means to modulate the relative stability of p53 and Mdm2 in response to cellular signals. In addition, they could be exploited for p53-activating therapies. This work shows that the degradation of proteins by the proteasome can be selectively dependent on S5a in human cells, and that this selectivity can extend to an E3 ubiquitin ligase and its substrate
Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70
Various subsets of invariant natural killer T (iNKT) cells with different cytokine productions develop in the mouse thymus, but the factors driving their differentiation remain unclear. Here we show that hypomorphic alleles of Zap70 or chemical inhibition of Zap70 catalysis leads to an increase of IFN-gamma-producing iNKT cells (NKT1 cells), suggesting that NKT1 cells may require a lower TCR signal threshold. Zap70 mutant mice develop IL-17-dependent arthritis. In a mouse experimental arthritis model, NKT17 cells are increased as the disease progresses, while NKT1 numbers negatively correlates with disease severity, with this protective effect of NKT1 linked to their IFN-gamma expression. NKT1 cells are also present in the synovial fluid of arthritis patients. Our data therefore suggest that TCR signal strength during thymic differentiation may influence not only IFN-gamma production, but also the protective function of iNKT cells in arthritis
- …
