PERAGAAN ONLINE KONSEP CHLADNI PLATE MENGGUNAKAN VIDEO DALAM MASA PANDEMI COVID – 19

Abstract Physics demonstration learning has been carried out with the theme "Physics Experiments You Can Do at Home During the Covid-19 Pandemic". This activity was carried out by making a simple physics experiment video entitled The Chladni Plate Concept which was then broadcasted online via a zoom platform to students of SMA Negeri 40. The theme carried was in accordance with the learning curriculum for Senior High School (SMA) students. This activity was carried out as an effort to respond to the Covid- 19 pandemic situation which requires students to carry out learning activities at home online, so it is hoped that this activity can increase understanding and stimulate student enthusiasm during the Distance Learning (PJJ) period. As confirmation that the activity gained enthusiasm and was able to achieve these goals, a research instrument was made consisting of several parameters which the instrument was distributed to the teacher and all participants. 96% confirmed that the material presented was very useful during a pandemic. This indicates that the physics demonstration presented in the form of a video can be an alternative for students of SMA Negeri 40 Jakarta in learning physics, especially in discussing physics experiments regarding the Chladni Plate Concept.   Abstrak Telah dilaksanakan pembelajaran peragaan fisika dengan tema “Eksperimen Fisika yang Bisa Dilakukan di Rumah Selama Pandemi Covid-19”. Kegiatan ini dilakukan dengan membuat video ekskperimen fisika sederhana berjudul Konsep Chladni Plate yang kemudian video tersebut ditayangkan secara daring melalui platform zoom kepada siswa/i SMA Negeri 40. Tema yang diusung sesuai dengan kurikulum pembelajaran untuk siswa Sekolah Menengah Atas (SMA). Kegiatan ini dilaksanakan sebagai upaya menyikapi situasi pandemi Covid-19 yang mengharuskan pelajar untuk melakukan kegiatan belajar di rumah secara daring, sehingga diharapkan kegiatan ini dapat meningkatkan pemahaman serta merangsang semangat siswa/i selama masa Pembelajaran Jarak Jauh (PJJ). Sebagai konfirmasi bahwa kegiatan mendapatkan antusiasme dan mampu mencapai tujuan tersebut, dibuatlah instrumen penelitian yang terdiri dari beberapa parameter dimana instrumen tersebut disebarkan kepada guru dan seluruh peserta. Terkonfirmasi sebanyak 96% menyatakan materi yang disampaikan sangat berguna di masa pandemi. Dengan ini mengindikasikan bahwa dengan peragaan fisika yang disajikan dalam bentuk video dapat menjadi alternatif bagi siswa/i SMA Negeri 40 Jakarta dalam belajar fisika khususnya dalam pembahasan eksperimen fisika mengenai Konsep Chladni Plate

Environmental Enrichment Preceding Early Adulthood Methylphenidate Treatment Leads to Long Term Increase of Corticosterone and Testosterone in the Rat

Attention-deficit/hyperactivity disorder (ADD/ADHD) has been emerging as a world-wide psychiatric disorder. There appears to be an increasing rate of stimulant drug abuse, specifically methylphenidate (MPH) which is the most common treatment for ADHD, among individuals who do not meet the criteria for ADHD and particularly for cognitive enhancement among university students. However, the long term effects of exposure to MPH are unknown. Thus, in light of a developmental approach in humans, we aimed to test the effects of adolescence exposure to enriched environment (EE) followed by MPH administration during early adulthood, on reactions to stress in adulthood. Specifically, at approximate adolescence [post natal days (PND) 30–60] rats were reared in EE and were treated with MPH during early adulthood (PND 60–90). Adult (PND 90–92) rats were exposed to mild stress and starting at PND 110, the behavioral and endocrine effects of the combined drug and environmental conditions were assessed. Following adolescence EE, long term exposure to MPH led to decreased locomotor activity and increased sucrose preference. EE had a beneficial effect on PPI (attentive abilities), which was impaired by long term exposure to MPH. Finally, the interaction between EE and, exposure to MPH led to long-term elevated corticosterone and testosterone levels. In view of the marked increase in MPH consumption over the past decade, vigilance is crucial in order to prevent potential drug abuse and its long term detrimental consequences

The effect of MPH on PPI.

<p>Significant differences in PPI scores were observed. EE led to the highest PPI compared with all groups (<i>P</i><0.0001). Following MPH treatment, the EES group showed higher PPI compared with control (<i>P</i><0.0001) and stress (<i>P</i><0.001) groups. A panel of representative traces demonstrate the differences in maximal response inhibition (at pre-intensity of 69 dB) of all four groups, with and without MPH. n = 9 to 10 per group.</p

The effect of MPH on locomotor activity.

<p>A significant difference in distance (A) and velocity (B) were detected between the groups in the open field test. Rats exposed to MPH following EE showed the lowest distance and velocity. These effects were not related to differences in body weight (C). MPH treatment significantly increased freezing duration (D) compared to saline. Following EE, MPH led to the highest freezing duration. * <i>P</i><0.0001 versus control; ** a: <i>P</i><0.022, b: <i>P</i><0.008, c: <i>P</i><0.0001 versus EE saline; n = 9 to 10 per group.</p

The effect of MPH on CORT and TST levels.

<p>A significant difference in CORT (A) and TST (B) levels was observed. MPH treatment significantly increased CORT level in the EE and EES groups (* P<0.0001; ** P<0.002 compared with their respective controls). TST level was similar across all groups, while MPH treatment increased TST level in both EE and EES groups (* P<0.001; ** P<0.012 compared with their counterpart controls). n = 9 to 10 per group.</p

The effect of MPH on sucrose preference test.

<p>Considerable variation in sucrose intake was observed between the groups. While significant long term anhedonia was detected in the EE group, MPH treatment following EE significantly recovers this effect. * <i>P</i><0.019 versus control; ** <i>P</i><0.0001 versus EE saline; n = 9 to 10 per group.</p

Schematic diagram of experimental design and procedures.

<p>Schematic diagram of experimental design and procedures.</p

Dog training alleviates PTSD symptomatology by emotional and attentional regulation

Background: Post-Traumatic Stress Disorder (PTSD) symptoms include re-experiencing, avoidance, hyperarousal, and cognitive deficits, reflecting both emotional and cognitive dysregulation. In recent years, non-pharmacological approaches and specifically animal-assisted therapy have been shown to be beneficial for a variety of disorders such as Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and PTSD. However, little is mentioned in the literature about the reciprocal effects of the animal–human interaction. Objective: To evaluate the effects of a one-year dog training programme on PTSD symptomatology in youngsters with PTSD and on dogs’ behaviour. Methods: Fifty-three adolescents, previously exposed to interpersonal trauma, were clinically diagnosed with PTSD and assigned to a dog-training programme group (n = 30) and a control group (n = 23) that engaged in other training programmes (e.g. cooking, hairstyling, etc.). Both groups were evaluated at baseline and following 12-months by The Clinician-Administered PTSD Scale for DSM-5 in Children and Adolescents (CAPS-CA-5) and Beck-Depression Inventory (BDI). Additionally, we physiologically measured both emotional and attention dysregulation. Results: Post-12-months training, a significant alleviation of PTSD symptomatology accompanied by lower depression severity was observed in the dog-training group, compared with a insignificant recovery in the control group. Furthermore, improved emotional and attentional regulation was observed in the dog-training group. Measuring the dogs’ behaviour revealed increased anxiety and decreased selective attention performance, which was inversely correlated with the beneficial effects observed in the dog-training programme group. Conclusions: Our findings emphasize the role of emotional and attentional regulations on the dog–handler interface, as evidence-based support for the beneficial effects of the dog-training programme, as either a non-pharmacological intervention or as complementary to anti-depressants treatment of PTSD. Though pharmacological treatments increase the patients’ well-being by treating certain PTSD symptoms, our suggested dog-training programme seems to influence the PTSD diagnostic status, thus may be implemented in civilians and veterans with PTSD

Methylphenidate and environmental enrichment ameliorate the deleterious effects of prenatal stress on attention functioning

<div><p></p><p>Either pre- or post-natal environmental factors seem to play a key role in brain and behavioral development and to exert long-term effects. Increasing evidence suggests that exposure to prenatal stress (PS) leads to motor and learning deficits and elevated anxiety, while enriched environment (EE) shows protective effects. The dopaminergic system is also sensitive to environmental life circumstances and affects attention functioning, which serves as the preliminary gate to cognitive processes. However, the effects of methylphenidate (MPH) on the dopaminergic system and attentional functioning, in the context of these life experiences, remain unclear. Therefore, we aimed to examine the effects of EE or PS on distinct types of attention, along with possible effects of MPH exposure. We found that PS impaired selective attention as well as partial sustained attention, while EE had beneficial effects. Both EE and MPH ameliorated the deleterious effects of PS on attention functioning. Considering the possible psychostimulant effect of MPH, we examined both anxiety-like behavior as well as motor learning. We found that PS had a clear anxiogenic effect, whereas EE had an anxiolytic effect. Nevertheless, the treatment with both MPH and/or EE recovered the deleterious effects of PS. In the motor-learning task, the PS group showed superior performance while MPH led to impaired motor learning. Performance decrements were prevented in both the PS + MPH and EE + MPH groups. This study provides evidence that peripubertal exposure to EE (by providing enhanced sensory, motor, and social opportunities) or MPH treatments might be an optional therapeutic intervention in preventing the PS long-term adverse consequences.</p></div