Risks Evaluation of Financial-Economic Activity and Their Management in the System of Economic Security of the Organization

Organizations increasingly need to improve approaches to enterprise management in connection with regularly occurring crisis phenomena in the modern economy. Any business entity must ensure timely reaction to changes in the external environment in order to avoid risks and threats to economic activity and to achieve the set goals. Well-organized management system of enterprise economic security can become a guarantee of this. Keywords: economic security, risks, financial and economic activity of the organization, audit, accounting, accounting (financial) report

Issue of Money Laundering Risks Identification in the Activity of the Organizations and Individual Entrepreneurs Engaged in the Mining, Production, Use and Circulation of Precious Metals and Precious Stones

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.Identification of money laundering risks in the sector of precious metals and precious stones is an important element in building an effective risk-based approach of money laundering risk assessment in the country. The article describes a mechanism of information exchange used in risk assessment of the organizations and individual entrepreneurs engaged in the mining, production, use and circulation of precious metals and precious stones. The mechanism is based on modern digital technologies such as a user’s cabinet on the Federal financial monitoring service website. The risk-score is obtained as a result of the analysis of the information contained in the database of Rosfinmonitoring, as well as monitoring and oversight activities conducted by Federal state institution «The risk-score shall be provided to all subjects of the sector allowing them to quickly resolve the shortcomings in their activities. Keywords: money laundering risk, sector of precious metals and precious stones, big data, information exchange, risk assessment, internal control

Deposition of TiN-based coatings using vacuum arc plasma in increased negative substrate bias voltage

The paper presents the results of the study on the influence of a high substrate bias voltage from 300 up to 1300 V on the titanium nitride coating deposition under nitrogen pressure of 2 Pa. The deposition rate, phase and chemical composition, adhesion and mechanical properties of coatings, macroparticle number and size distribution were investigated.Представлені результати дослідження впливу високої напруги зсуву підкладки від 300 до 1300 В на осадження покриттів нітриду титану при тиску азоту 2 Па. Вивчені швидкість осадження, фазовий і хімічний склад, адгезія і механічні властивості покриттів, кількість і розподіл за розмірами макрочасток.Представлены результаты исследования влияния высокого напряжения смещения подложки от 300 до 1300 В на осаждение покрытий нитрида титана при давлении азота 2 Па. Изучены скорость осаждения, фазовый и химический составы, адгезия и механические свойства покрытий, количество и распределение по размерам макрочастиц

Titanium in Shipbuilding and Other Technical Applications

Aerospace industry is currently the major consumer of titanium in Russia. Shipbuilding is its second largest consumer. Oil and gas, chemical, pulp-and-paper and other industries use less titanium. In the Russian industrial sector titanium is geting more applicable. Since the 13th World Ti-2015 Conference the titanium application trends have persisted [1]. Among the major development trends of titanium alloys one should note the development of titanium alloys for deep-water marine facilities, case designs of small-size nuclear power plants, the development of additive technologies, the technologies of isostatic pressing, the development of titanium products by new production facilities, etc. Titanium is still considered an advanced structural material used for scientific and technical progress in different industrial sectors

Comparative Analysis of the Paracrine Action of Neuronal and Glial Progenitor Cells Derived from Induced Human Pluripotent Stem Cells

We performed comparative analysis of paracrine activity of neuronal and glial progenitors derived from induced pluripotent stem cells under conditions of hypoxia modeled by addition of cobalt dichloride. Neuronal and glial progenitors produced neuroprotective and neurotrophic effects on SHSY-5Y neuroblastoma cells in co-culture during the post-hypoxic recovery and reduced the number of apoptotic and necrotic cells. Moreover, they produced a neurotrophic effect and promote the formation and growth of neurites in neuroblastoma cells. The paracrine effect of glial progenitors was more pronounced, which can be explained by more intensive expression and secretion of neurotrophic factors in these cells. © 2020, Springer Science+Business Media, LLC, part of Springer Nature

Сравнительный анализ паракринного действия нейрональных и глиальных предшественников, полученных из индуцированных плюрипотентных стволовых клеток человека

The article is focused on comparative analysis of the in vitro paracrine activity shown by the induced pluripotent stem cell-derived neuronal and glial progenitors and directed towards SHSY-5Y neuroblastoma cells during the recovery from hypoxic stress modeled by the exposure to cobalt dichloride. Co-cultivation with neuronal and glial progenitors exerted neuroprotective and neurotrophic effects on SHSY-5Y cells during the post-hypoxic recovery, reducing the number of apoptotic and necrotic cells and supporting neurite outgrowth. Moreover, the paracrine effect of glial progenitors was more pronounced compared to neuronal progenitors, which may be explained by a higher level of expression and secretion of neurotrophic factors by glial progenitors.Проведён сравнительный анализ паракринной активности нейрональных и глиальных предшественников, полученных из индуцированных плюрипотентных стволовых клеток, при моделировании гипоксии добавлением дихлорида кобальта. Сокультивирование с нейрональными и глиальными предшественниками оказывало нейропротективное действие на клетки нейробластомы SHSY-5Y, снижая количество апоптотических и некротических клеток в культуре. Кроме того, сокультивирование обеспечивало нейротрофический эффект, способствуя нейритогенезу в клетках линии SHSY-5Y. При этом паракринное влияние глиальных предшественников было более выраженным, что может объясняться более высоким уровнем экспрессии нейротрофических факторов в данных клетках