35 research outputs found
Risks Evaluation of Financial-Economic Activity and Their Management in the System of Economic Security of the Organization
Organizations increasingly need to improve approaches to enterprise management in connection with regularly occurring crisis phenomena in the modern economy. Any business entity must ensure timely reaction to changes in the external environment in order to avoid risks and threats to economic activity and to achieve the set goals. Well-organized management system of enterprise economic security can become a guarantee of this.Β Keywords: economic security, risks, financial and economic activity of the organization, audit, accounting, accounting (financial) report
Issue of Money Laundering Risks Identification in the Activity of the Organizations and Individual Entrepreneurs Engaged in the Mining, Production, Use and Circulation of Precious Metals and Precious Stones
This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.Identification of money laundering risks in the sector of precious metals and precious stones is an important element in building an effective risk-based approach of money laundering risk assessment in the country. The article describes a mechanism of information exchange used in risk assessment of the organizations and individual entrepreneurs engaged in the mining, production, use and circulation of precious metals and precious stones. The mechanism is based on modern digital technologies such as a userβs cabinet on the Federal financial monitoring service website. The risk-score is obtained as a result of the analysis of the information contained in the database of Rosfinmonitoring, as well as monitoring and oversight activities conducted by Federal state institution Β«The risk-score shall be provided to all subjects of the sector allowing them to quickly resolve the shortcomings in their activities.Β Keywords: money laundering risk, sector of precious metals and precious stones, big data, information exchange, risk assessment, internal control
Deposition of TiN-based coatings using vacuum arc plasma in increased negative substrate bias voltage
The paper presents the results of the study on the influence of a high substrate bias voltage from 300 up to 1300 V on the titanium nitride coating deposition under nitrogen pressure of 2 Pa. The deposition rate, phase and chemical composition, adhesion and mechanical properties of coatings, macroparticle number and size distribution were investigated.ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΈ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ Π²ΠΏΠ»ΠΈΠ²Ρ Π²ΠΈΡΠΎΠΊΠΎΡ Π½Π°ΠΏΡΡΠ³ΠΈ Π·ΡΡΠ²Ρ ΠΏΡΠ΄ΠΊΠ»Π°Π΄ΠΊΠΈ Π²ΡΠ΄ 300 Π΄ΠΎ 1300 Π Π½Π° ΠΎΡΠ°Π΄ΠΆΠ΅Π½Π½Ρ ΠΏΠΎΠΊΡΠΈΡΡΡΠ² Π½ΡΡΡΠΈΠ΄Ρ ΡΠΈΡΠ°Π½Ρ ΠΏΡΠΈ ΡΠΈΡΠΊΡ Π°Π·ΠΎΡΡ 2 ΠΠ°. ΠΠΈΠ²ΡΠ΅Π½Ρ ΡΠ²ΠΈΠ΄ΠΊΡΡΡΡ ΠΎΡΠ°Π΄ΠΆΠ΅Π½Π½Ρ, ΡΠ°Π·ΠΎΠ²ΠΈΠΉ Ρ Ρ
ΡΠΌΡΡΠ½ΠΈΠΉ ΡΠΊΠ»Π°Π΄, Π°Π΄Π³Π΅Π·ΡΡ Ρ ΠΌΠ΅Ρ
Π°Π½ΡΡΠ½Ρ Π²Π»Π°ΡΡΠΈΠ²ΠΎΡΡΡ ΠΏΠΎΠΊΡΠΈΡΡΡΠ², ΠΊΡΠ»ΡΠΊΡΡΡΡ Ρ ΡΠΎΠ·ΠΏΠΎΠ΄ΡΠ» Π·Π° ΡΠΎΠ·ΠΌΡΡΠ°ΠΌΠΈ ΠΌΠ°ΠΊΡΠΎΡΠ°ΡΡΠΎΠΊ.ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π²Π»ΠΈΡΠ½ΠΈΡ Π²ΡΡΠΎΠΊΠΎΠ³ΠΎ Π½Π°ΠΏΡΡΠΆΠ΅Π½ΠΈΡ ΡΠΌΠ΅ΡΠ΅Π½ΠΈΡ ΠΏΠΎΠ΄Π»ΠΎΠΆΠΊΠΈ ΠΎΡ 300 Π΄ΠΎ 1300 Π Π½Π° ΠΎΡΠ°ΠΆΠ΄Π΅Π½ΠΈΠ΅ ΠΏΠΎΠΊΡΡΡΠΈΠΉ Π½ΠΈΡΡΠΈΠ΄Π° ΡΠΈΡΠ°Π½Π° ΠΏΡΠΈ Π΄Π°Π²Π»Π΅Π½ΠΈΠΈ Π°Π·ΠΎΡΠ° 2 ΠΠ°. ΠΠ·ΡΡΠ΅Π½Ρ ΡΠΊΠΎΡΠΎΡΡΡ ΠΎΡΠ°ΠΆΠ΄Π΅Π½ΠΈΡ, ΡΠ°Π·ΠΎΠ²ΡΠΉ ΠΈ Ρ
ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΠΎΡΡΠ°Π²Ρ, Π°Π΄Π³Π΅Π·ΠΈΡ ΠΈ ΠΌΠ΅Ρ
Π°Π½ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ²ΠΎΠΉΡΡΠ²Π° ΠΏΠΎΠΊΡΡΡΠΈΠΉ, ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΈ ΡΠ°ΡΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΏΠΎ ΡΠ°Π·ΠΌΠ΅ΡΠ°ΠΌ ΠΌΠ°ΠΊΡΠΎΡΠ°ΡΡΠΈΡ
A posteriori accuracy estimations of solutions to ill-posed inverse problems and extra-optimal regularizing algorithms for their solution
Titanium in Shipbuilding and Other Technical Applications
Aerospace industry is currently the major consumer of titanium in Russia. Shipbuilding is its second largest consumer. Oil and gas, chemical, pulp-and-paper and other industries use less titanium. In the Russian industrial sector titanium is geting more applicable. Since the 13th World Ti-2015 Conference the titanium application trends have persisted [1]. Among the major development trends of titanium alloys one should note the development of titanium alloys for deep-water marine facilities, case designs of small-size nuclear power plants, the development of additive technologies, the technologies of isostatic pressing, the development of titanium products by new production facilities, etc. Titanium is still considered an advanced structural material used for scientific and technical progress in different industrial sectors
Comparative Analysis of the Paracrine Action of Neuronal and Glial Progenitor Cells Derived from Induced Human Pluripotent Stem Cells
We performed comparative analysis of paracrine activity of neuronal and glial progenitors derived from induced pluripotent stem cells under conditions of hypoxia modeled by addition of cobalt dichloride. Neuronal and glial progenitors produced neuroprotective and neurotrophic effects on SHSY-5Y neuroblastoma cells in co-culture during the post-hypoxic recovery and reduced the number of apoptotic and necrotic cells. Moreover, they produced a neurotrophic effect and promote the formation and growth of neurites in neuroblastoma cells. The paracrine effect of glial progenitors was more pronounced, which can be explained by more intensive expression and secretion of neurotrophic factors in these cells. Β© 2020, Springer Science+Business Media, LLC, part of Springer Nature
Π‘ΡΠ°Π²Π½ΠΈΡΠ΅Π»ΡΠ½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΏΠ°ΡΠ°ΠΊΡΠΈΠ½Π½ΠΎΠ³ΠΎ Π΄Π΅ΠΉΡΡΠ²ΠΈΡ Π½Π΅ΠΉΡΠΎΠ½Π°Π»ΡΠ½ΡΡ ΠΈ Π³Π»ΠΈΠ°Π»ΡΠ½ΡΡ ΠΏΡΠ΅Π΄ΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΈΠΊΠΎΠ², ΠΏΠΎΠ»ΡΡΠ΅Π½Π½ΡΡ ΠΈΠ· ΠΈΠ½Π΄ΡΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ ΠΏΠ»ΡΡΠΈΠΏΠΎΡΠ΅Π½ΡΠ½ΡΡ ΡΡΠ²ΠΎΠ»ΠΎΠ²ΡΡ ΠΊΠ»Π΅ΡΠΎΠΊ ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ°
The article is focused on comparative analysis of the in vitro paracrine activity shown by the induced pluripotent stem cell-derived neuronal and glial progenitors and directed towards SHSY-5Y neuroblastoma cells during the recovery from hypoxic stress modeled by the exposure to cobalt dichloride. Co-cultivation with neuronal and glial progenitors exerted neuroprotective and neurotrophic effects on SHSY-5Y cells during the post-hypoxic recovery, reducing the number of apoptotic and necrotic cells and supporting neurite outgrowth. Moreover, the paracrine effect of glial progenitors was more pronounced compared to neuronal progenitors, which may be explained by a higher level of expression and secretion of neurotrophic factors by glial progenitors.ΠΡΠΎΠ²Π΅Π΄ΡΠ½ ΡΡΠ°Π²Π½ΠΈΡΠ΅Π»ΡΠ½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΏΠ°ΡΠ°ΠΊΡΠΈΠ½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π½Π΅ΠΉΡΠΎΠ½Π°Π»ΡΠ½ΡΡ
ΠΈ Π³Π»ΠΈΠ°Π»ΡΠ½ΡΡ
ΠΏΡΠ΅Π΄ΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΈΠΊΠΎΠ², ΠΏΠΎΠ»ΡΡΠ΅Π½Π½ΡΡ
ΠΈΠ· ΠΈΠ½Π΄ΡΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΏΠ»ΡΡΠΈΠΏΠΎΡΠ΅Π½ΡΠ½ΡΡ
ΡΡΠ²ΠΎΠ»ΠΎΠ²ΡΡ
ΠΊΠ»Π΅ΡΠΎΠΊ, ΠΏΡΠΈ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ Π³ΠΈΠΏΠΎΠΊΡΠΈΠΈ Π΄ΠΎΠ±Π°Π²Π»Π΅Π½ΠΈΠ΅ΠΌ Π΄ΠΈΡ
Π»ΠΎΡΠΈΠ΄Π° ΠΊΠΎΠ±Π°Π»ΡΡΠ°. Π‘ΠΎΠΊΡΠ»ΡΡΠΈΠ²ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ Ρ Π½Π΅ΠΉΡΠΎΠ½Π°Π»ΡΠ½ΡΠΌΠΈ ΠΈ Π³Π»ΠΈΠ°Π»ΡΠ½ΡΠΌΠΈ ΠΏΡΠ΅Π΄ΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΈΠΊΠ°ΠΌΠΈ ΠΎΠΊΠ°Π·ΡΠ²Π°Π»ΠΎ Π½Π΅ΠΉΡΠΎΠΏΡΠΎΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ΅ Π΄Π΅ΠΉΡΡΠ²ΠΈΠ΅ Π½Π° ΠΊΠ»Π΅ΡΠΊΠΈ Π½Π΅ΠΉΡΠΎΠ±Π»Π°ΡΡΠΎΠΌΡ SHSY-5Y, ΡΠ½ΠΈΠΆΠ°Ρ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ Π°ΠΏΠΎΠΏΡΠΎΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈ Π½Π΅ΠΊΡΠΎΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΊΠ»Π΅ΡΠΎΠΊ Π² ΠΊΡΠ»ΡΡΡΡΠ΅. ΠΡΠΎΠΌΠ΅ ΡΠΎΠ³ΠΎ, ΡΠΎΠΊΡΠ»ΡΡΠΈΠ²ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠΈΠ²Π°Π»ΠΎ Π½Π΅ΠΉΡΠΎΡΡΠΎΡΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΡΡΠ΅ΠΊΡ, ΡΠΏΠΎΡΠΎΠ±ΡΡΠ²ΡΡ Π½Π΅ΠΉΡΠΈΡΠΎΠ³Π΅Π½Π΅Π·Ρ Π² ΠΊΠ»Π΅ΡΠΊΠ°Ρ
Π»ΠΈΠ½ΠΈΠΈ SHSY-5Y. ΠΡΠΈ ΡΡΠΎΠΌ ΠΏΠ°ΡΠ°ΠΊΡΠΈΠ½Π½ΠΎΠ΅ Π²Π»ΠΈΡΠ½ΠΈΠ΅ Π³Π»ΠΈΠ°Π»ΡΠ½ΡΡ
ΠΏΡΠ΅Π΄ΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΈΠΊΠΎΠ² Π±ΡΠ»ΠΎ Π±ΠΎΠ»Π΅Π΅ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΡΠΌ, ΡΡΠΎ ΠΌΠΎΠΆΠ΅Ρ ΠΎΠ±ΡΡΡΠ½ΡΡΡΡΡ Π±ΠΎΠ»Π΅Π΅ Π²ΡΡΠΎΠΊΠΈΠΌ ΡΡΠΎΠ²Π½Π΅ΠΌ ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΠΈ Π½Π΅ΠΉΡΠΎΡΡΠΎΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ² Π² Π΄Π°Π½Π½ΡΡ
ΠΊΠ»Π΅ΡΠΊΠ°Ρ