Universal geometric classification of armchair honeycomb nanoribbons by their properties in a staggered sublattice potential

We demonstrate the topological band-gap dependence of armchair honeycomb nanoribbons in a staggered sublattice potential. A scaling law is presented to quantify the band gap variation with potential strength. All armchair nanoribbons are described by one of three distinct classes depending on their width, consistent with previous classifications, namely, the well known massless Dirac condition, potentially gapless, and gapless-superlattice. The ability to tune and, in all cases close, the band-gap via external probes makes our classification particularly relevant experimentally. We propose several systems in which these results should shed considerable light, which have all already been experimentally realized

An integrated water balance model for assessing water scarcity in a data-sparse interfluve in Eastern India

The objective of this study is to measure the balance of water demand versus water resource availability in an interfluve of West Bengal, India to support water resource planning, particularly of inter-basin transfers. Surface water availability was modelled using the Soil Conservation Service Curve Number (SCS-CN) model, whilst groundwater availability was modelled based on water level fluctuations and the rainfall infiltration method. Water use was modelled separately for the agricultural, industrial, and domestic sectors using a predominantly normative approach and water use to availability ratios calculated for different administrative areas within the interfluve. Overall, the approach suggested that the interfluve receives 327×106m3year?1 of excess water after satisfying these sectoral demands, but that the eastern part of the study area is in deficit. However, a sensitivity analysis carried on the approach to several assumptions in the model suggested changed circumstances would produce surplus/deficit ranging from -215×106m3year?1 to 435 ×106m3year?1 . The approach could have potential for localised water balance modelling in other Indian catchment

Galactic Plane Hα\alpha Surveys: IPHAS & VPHAS+

The optical Galactic Plane H$\alpha$ surveys IPHAS and VPHAS+ are dramatically improving our understanding of Galactic stellar populations and stellar evolution by providing large samples of stars in short lived, but important, evolutionary phases, and high quality homogeneous photometry and images over the entire Galactic Plane. Here I summarise some of the contributions these surveys have already made to our understanding of a number of key areas of stellar and Galactic astronomy.Comment: 5 pages, 2 figures, refereed proceeding of the "The Universe of Digital Sky Surveys" conference, November 2014, to be published in the Astrophysics and Space Science Proceeding

The Spectral and Temporal Properties of Transient Sources in Early-type Galaxies

Copyright 2012 Elsevier B.V., All rights reserved.We report the spectral and temporal variability properties of 18 candidate transient (TC) and potential transient (PTC) sources detected in deep multi-epoch Chandra observation of the nearby elliptical galaxies, NGC3379, NGC4278, and NGC4697. Only one source can be identified with a background counterpart, leaving 17 TCs + PTCs in the galaxies. Of these, 14 are in the galaxy field, supporting the theoretical picture that the majority of field X-ray binaries (XRBs) will exhibit transient accretion for >75% of their lifetime. Three sources are coincident with globular clusters, including two high-luminosity candidate black hole (BH) XRBs, with Lx= 5.4 × 10 erg/s and Lx= 2.8 × 10 erg/s, respectively. The spectra, luminosities, and temporal behavior of these 17 sources suggest that the transient population is heterogeneous, including neutron star (NS) and BH XRBs in both normal and high-rate accretion modes, and super soft sources containing white dwarf binaries. Our TC and PTC detections are noticeably fewer than the number expected from the population synthesis (PS) models of Fragos et al., tailored to our new Chandra pointings of NGC4278. We attribute this discrepancy to the PS assumption that the transient population is composed of NS XRBs, as well as differences between the statistical analysis and error estimates used in the model and our observationsPeer reviewe

Comparison of Munsell® color chart assessments with primary schoolchildren's self-reported skin color

BACKGROUND : Skin color is related to human health outcomes, including the risks of skin cancer and vitamin D insufficiency. Self-perceptions of skin color may influence health behaviours, including the adoption of practices protective against harmful solar ultraviolet radiation levels. Misperception of personal risk may have negative health implications. The aim of this study is to determine whether Munsell color chart assessments align with child self-reported skin color. METHODS : Two-trained investigators, with assessed color acuity, visually classified student inner upper arm constitutive skin color. The Munsell classifications obtained were converted to Individual Typology Angle (ITA) values and respective Del Bino skin color categories after spectrocolorimeter measurements based on published values/data. As part of a written questionnaire on sun protection knowledge, attitudes, and behaviours, self-completed in class time, students classified their end of winter skin color. Student self-reports were compared with the ITA-based Del Bino classifications. A total of 477 New Zealand primary students attending 27 randomly selected schools from five geographic regions. The main measures were selfreported skin color and visually observed skin color. RESULTS : A monotonic association was observed between the distribution of spectrophotometer ITA scores obtained for Munsell tiles and child self-reports of skin color, providing some evidence for the validity of self-report among New Zealand primary school children, although the lighter colored ITA defined groups were most numerous in this study sample. Statistically significant differences in ITA scores were found by ethnicity, self-reported skin color, and geographic residence (P < 0.001). Certain Munsell color tiles were frequently selected as providing a best match to skin color. CONCLUSION : Assessment using Munsell color charts was simple, inexpensive, and practical for field use and acceptable to children. The results suggest that this method may prove useful for making comparisons with other studies using visual tools to assess skin color. Alignment between the ITA distribution derived from the Munsell assessment and child skin color self-reports could probably be improved, particularly with the addition of another ‘light’/’white’ color category in the self-report instrument.The Cancer Society of New Zealand Inc., the National Institute of Water and Atmospheric Research, the National Research Foundation of South Africa and the University of Otago.http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1600-08462016-11-30hb2016Geography, Geoinformatics and Meteorolog

Assessing connectivity in South Australia's Marine Parks Network

Alice Jones, Michelle Waycott, Simon Bryars, Alison Wright and Bronwyn Gillander

First-principles prediction of structure, energetics, formation enthalpy, elastic constants, polarization, and piezoelectric constants of AlN, GaN, and InN: comparison of local and gradient-corrected density-functional theory

A number of diverse bulk properties of the zincblende and wurtzite III-V nitrides AlN, GaN, and InN, are predicted from first principles within density functional theory using the plane-wave ultrasoft pseudopotential method, within both the LDA (local density) and GGA (generalized gradient) approximations to the exchange-correlation functional. Besides structure and cohesion, we study formation enthalpies (a key ingredient in predicting defect solubilities and surface stability), spontaneous polarizations and piezoelectric constants (central parameters for nanostructure modeling), and elastic constants. Our study bears out the relative merits of the two density functional approaches in describing diverse properties of the III-V nitrides (and of the parent species N$_2$, Al, Ga, and In), and leads us to conclude that the GGA approximation, associated with high-accuracy techniques such as multiprojector ultrasoft pseudopotentials or modern all-electron methods, is to be preferred in the study of III-V nitrides.Comment: RevTeX 6 pages, 12 tables, 0 figure

Deletion of the protein tyrosine phosphatase PTPN22 for adoptive T cell therapy facilitates CTL effector function but promotes T cell exhaustion

Background: Adoptive cell therapy (ACT) is a promising strategy for treating cancer, yet it faces several challenges such as lack of long-term protection due to T cell exhaustion induced by chronic TCR stimulation in the tumor microenvironment. One benefit of ACT, however, is that it allows for cellular manipulations, such as deletion of the phosphotyrosine phosphatase non-receptor type 22 (PTPN22), which improves CD8+ T cell antitumor efficacy in ACT. We tested whether Ptpn22KO cytolytic T cells (CTLs) were also more effective than Ptpn22WT CTL in controlling tumors in scenarios that favor T cell exhaustion. Methods: Tumor control by Ptpn22WT and Ptpn22KO CTL was assessed following adoptive transfer of low numbers of CTL to mice with subcutaneously implanted MC38 tumors. Tumor infiltrating lymphocytes were isolated for analysis of effector functions. An in vitro assay was established to compare CTL function in response to acute and chronic restimulation with antigen-pulsed tumor cells. The expression of effector and exhaustion-associated proteins by Ptpn22WT and Ptpn22KO T cells was followed over time in vitro and in vivo using the ID8 tumor model. Finally, the effect of PD-1 and TIM-3 blockade on Ptpn22KO CTL tumor control was assessed using monoclonal antibodies and CRISPR/Cas9-mediated knockout. Results: Despite having improved effector function at the time of transfer, Ptpn22KO CTL became more exhausted than Ptpn22WT CTL, characterized by more rapid loss of effector functions, and earlier and higher expression of inhibitory receptors (IRs), particularly the terminal exhaustion marker TIM-3. TIM-3 expression, under the control of the transcription factor NFIL3, was induced by IL-2 signaling which was enhanced in Ptpn22KO cells. Antitumor responses of Ptpn22KO CTL were improved following PD-1 blockade in vivo, yet knockout or antibody-mediated blockade of TIM-3 did not improve but further impaired tumor control, indicating TIM-3 signaling itself did not drive the diminished function seen in Ptpn22KO CTL. Conclusions: This study questions whether TIM-3 plays a role as an IR and highlights that genetic manipulation of T cells for ACT needs to balance short-term augmented effector function against the risk of T cell exhaustion in order to achieve longer-term protection