Nigeria Paper Currency Serial Number Pattern Recognition System for Crimes Control

Only secured and conducive environment void of robbery, kidnapping, fake currency and all forms of insurgencies will foster production and distribution of goods, investment and saving that enhance national economic growth and development. This is a mirage in a country generally believed and tagged the giant of African; Nigeria. Crime, in whatever name or nomenclature, has a significant negative impact on the welfare and economy prosperities of our society. The urge to get rich promotes Crime like armed robbery, kidnapping for ransom and production of counterfeit banknotes to mention but a few. Innocent people have suffered psychological distress, fear, anger, depression, physical harm, financial loss and in most cases untimely death during the operations by these hoodlums. Banks, Cash-In-Transit Vehicle, and ATM points are often robbed by gangs in search for paper currency. Kidnappers as well demand for paper currency as ransom while some other gangs are involved in the production of counterfeit banknotes so as to enrich themselves no minding the negative effect on the nation’s economy.  The banknotes collected during the operations by the hoodlums are taken to banks. Yet, the banks will not detect or recognize any of these notes which attest to the fact that our system lacks check and balance. The system is very porous without a recourse to this era of technology when machine is trained to do virtually everything for our convenience. Currency as an entity has a unique identification number. The identification number is an alphanumeric currency issuance of about 10 digits comprises two (2) capital letters and eight (8) numbers usually positioned at a strategic location on either front or back of the 5, 10, 20, 50, 100, 200, 500 and 1000 naira notes. It is a reliable and intelligent system developed to track banknotes unique identifiers numbers- serial numbers, in order to control financial related crimes. Keywords: Nigeria Paper Currency Serial Number, Pattern Recognition DOI: 10.7176/IKM/11-3-04 Publication date: April 30th 202

Prevalence of pulmonary cryptococcosis in hiv/aids patients

Cryptococcus neoformans causes both pulmonary and meninges infection in healthy and immunocompromised hosts. The objective of this study was to determine the prevalence of pulmonary cryptococcosis in HIV/AIDS patients and assess the clinical presentations due to the infection. The subjects recruited for this study were confirmed HIV/AIDS patients, presenting with pneumonia complications. The demographic and clinical features were abstracted from the medical records and administered questionnaire. Early morning sputum samples were collected from the patients and examined by bacteriological methods. The isolated Cryptococcus neoformans were sub-cultured onto thistle bird seed agar and the identity was confirmed with API 20C Kit. Out of 250 patients investigated, 47 (18.8%) had pulmonary cryptococcosis. The C.neoformans isolates were more in females, 26 (10.4%) than the males, 21 (8.4%), while the age group of 20-40 years old had 39 (15.6%) isolates. The clinical features that were associated with the pulmonary cryptococcosis were the productionof purulent and bloody sputum, and fever. The patients with prolonged duration of HIV/AIDS and are not on HAART regimens had higher C.neoformans isolates. The isolation of C.neoformans from HIV/AIDS patients is a major public health concern, since it complicatesthe severity of the disease. There is a need for routine check of pulmonary cryptococcosis, especially, in those who do not avail themselves for antiretroviral therapy.Keywords: Cryptococcus neoformans, Cryptoccosis, HIV/AIDS, HAART, Thistle bird seed agar

Hybrid Design using Counter Propagation Neural Network-Genetic Algorithm Model for the Anomaly Detection in Online Transaction

In e-commerce, credit card fraud is an evolving challenge. The increase in the number of credit card transactions provides more opportunity for fraudsters to steal credit card numbers and execute fraud. Fraud detection is a continuously evolving discipline to tackle ever changing tactics to commit fraud. Existing fraud detection systems have not been so much efficient to reduce fraud transaction rate. Improvement in fraud detection practices has become essential to maintain existence of payment system. This research designed hybrid of Counter Propagation Neural Network and genetic algorithm (CPNN-GA) for the detection of anomaly in any online transactions

Detection and genetic characterization of orf virus from sheep and goats in Nigeria

Orf is a contagious, viral epitheliotropic disease of small ruminants. We investigated the molecular epidemiology of orf virus (ORFV) in breeds of small ruminants to determine the evolutionary diversity in Nigeria. Out of 54 small ruminants screened, the number of animals that were positive for ORFV in the three locations were 25. The distribution of positive animals by location were FCT 45.0% (n = 9/20), Oyo State 42.9% (6/14), and Plateau State 50.0% (n = 10/20). ORFV sequences from this study clustered with viruses detected in Taiwan, Iran, USA, and France. Our findings highlight the risk of transmission across geographic boundaries in Nigeria and West Africa, and reinforces the need for increased surveillance to prevent and control spread. Comprehensive characterization of ORFV in small ruminants as well as in humans in Nigeria is required to better elucidate the epidemiological dynamics and the virus evolution

Serum ferritin levels in adults with sickle cell disease in Lagos, Nigeria

Background: Serum ferritin is considered to be one of the most important tools in the measurement of iron balance in steady-state sickle cell disease. Increased gastrointestinal absorption of iron has been reported in sickle cell disease because of the associated chronic hemolysis, and it is also thought that repeated red cell transfusion consequent to chronic hemolysis and anemia causes excessive iron levels. The aim of this study was to determine overall and gender-specific mean ferritin levels in patients with steady-state sickle cell disease in order to establish the prevalence of iron deficiency and overload. Methods: This was a cross-sectional study in homozygous patients with sickle cell disease attending the sickle cell clinic at Lagos State University Teaching Hospital, Ikeja. A 5 mL blood sample was collected in plain bottles from consenting participants during steady-state periods. The serum was separated and analyzed for ferritin by enzyme-linked immunosorbent assay. Another 5 mL sample was collected for a full blood count, done on the same day of collection, to determine red blood cell indices, ie, mean cell volume, mean cell hemoglobin concentration, and mean corpuscular hemoglobin concentration. The Pearson Chi-square test was used for statistical analysis. The differences were considered to be statistically significant when P was <0.05. Results: In total, 103 patients were recruited for this study and comprised 58 women (56.40%) and 45 men (43.70%). The overall mean ferritin concentration was 93.72 ± 92.24 ng/mL. The mean ferritin concentration in the women was 92.00 ± 88.07 ng/mL and in men was 96.41 ± 99.80 ng/mL. Only eight (7.76%) of the 103 patients had a serum ferritin level 300 ng/mL. Ninety-three subjects (90.29%) had serum ferritin within the normal reference range of 15–300 ng/mL. Conclusion: In this study, 90% of subjects with sickle cell disease had normal iron stores; serum ferritin was higher in men than in women, and iron deficiency was more common than overload in the disease

Prognostic Impact of Pretreatment Thrombocytosis in Epithelial Ovarian Cancer

Aims:&nbsp;This study was aimed at investigating the prognostic impact of pretreatment thrombocytosis in epithelial ovarian cancer (EOC) patients in Lagos, Nigeria.&nbsp;Methods:&nbsp;This was a retrospective cohort study involving the review of the clinical record of 72 patients with histologically confirmed EOC who were managed at the Lagos University Teaching Hospital, Lagos, Nigeria over a 7-year period from January 2010 to December 2016. Information on the sociodemographic data and platelet counts at diagnosis of EOC were retrieved from the patients' medical records. Descriptive statistics were then computed for all baseline patients' characteristics. Survival analyses were carried out using the Kaplan-Meier estimates. Multivariate analysis of these data was performed with the Cox proportional hazards model.&nbsp;Results:&nbsp;This study revealed that the prevalence of pretreatment thrombocytosis was 41.7% among the women with EOC. Fifty-three (73.6%) of the women had the advanced-stage disease (FIGO stage III-IV) while 52 (72.2%) had high-grade disease (II-III). The majority (66.7%) of the women had a serous histological type of EOC while 76.4% had documented recurrence. Pretreatment thrombocytosis was significantly associated with the women's parity (P&nbsp;= 0.009), serum carbohydrate antigen 125 levels (P&nbsp;= 0.018), median progression-free survival (PFS) (P&nbsp;&lt; 0.001), 3-year median overall survival (OS) (P&nbsp;&lt; 0.001), type of primary treatment (P&nbsp;= 0.002), extent of cytoreduction (P&nbsp;&lt; 0.001), presence of ascites (P&nbsp;= 0.002), International Federation of Gynecology and Obstetrics (FIGO) stage (P&nbsp;= 0.008), and histological type (P&nbsp;= 0.011). Pretreatment thrombocytosis was negatively associated with PFS (hazard ratio [HR] = 0.25; 95% CI 0.83, 0.75;&nbsp;P&nbsp;= 0.014) and 3-year OS (HR = 0.03; 95% CI 0.03, 0.27;&nbsp;P&nbsp;= 0.002).&nbsp;Conclusions:&nbsp;The study suggests that pretreatment thrombocytosis may be a useful predictor of survivals in EOC patients

Hematological profile of normal pregnant women in Lagos, Nigeria

Background: Hematological profile is considered one of the factors affecting pregnancy and its outcome. Anemia is the most common hematological problem in pregnancy, followed by thrombocytopenia. Leukocytosis is almost always associated with pregnancy. The study reported here was designed to evaluate the overall mean values of seven major hematological parameters and their mean values at different trimesters of pregnancy. Subjects and methods: This examination was a cross-sectional study of 274 pregnant women who registered to attend the Lagos University Teaching Hospital or Lagos State University Teaching Hospital antenatal clinics between their first and third trimester. Blood (4.5 mL) was collected from each participant into a tube containing the anticoagulant ethylenediaminetetraacetic acid (EDTA). A full blood count was performed on each sample and the results were analyzed. Results: Overall, the values obtained were (mean ± standard deviation [SD]): hematocrit level, 30.16% ± 5.55%; hemoglobin concentration, 10.94 ± 1.86 g/dL; white blood cells, 7.81 ± 2.34 × 109; platelets, 228.29 ± 65.6 × 109; cell volume 78.30 ± 5.70 fL, corpuscular hemoglobin, 28.57 ± 2.48 pg; and corpuscular hemoglobin concentration, 36.45 ± 1.10 g/dL. When grouped by trimester, the mean ± SD value of packed cell volume at first trimester was 32.07% ± 6.80%; of second trimester, 29.76% ± 5.21%; and of third, 33.04% ± 3.88%. The mean ± SD hemoglobin concentration values were 11.59 ± 2.35 g/dL, 10.81 ± 1.72 g/dL, and 10.38 ± 1.27 g/dL for women in their first, second, and third trimester, respectively. Mean ± SD white blood cell concentration for first, second, and third trimesters were 7.31 ± 2.38 × 109, 7.88 ± 2.33 × 109, and 8.37 ± 2.15 × 109, respectively, while the mean ± SD platelet values for first, second, and third trimesters were 231.50 ± 79.10 × 109, 227.57 ± 63 × 109, and 200.82 ± 94.42 × 109, respectively. A statistically significant relationship was found to exist between packed cell volume and white blood cell count with increase in gestational age (P = 0.010 and 0.001, respectively). However, there was no statistically significant association between platelet count and increase in gestational age (P = 0.296). Conclusion: These findings reinforce the need for supplementation and provide additional information on hematological reference values in pregnancy in Nigeria

Cluster of differentiation 4+ cell count mean value, reference range and its influencing factors in Human Immunodeficiency Virus-seronegative pregnant women in Lagos

Background: Immunity in pregnancy is physiologically compromised and this may affect cluster of differentiation four (CD4) count levels. It is well established that several factors affect CD4 count level in pregnancy. This study aims to determine the effects of maternal age, gestational age, parity and level of education as they influence CD4 count in pregnancy and also to determine the mean and reference range of CD4 count in pregnancy in Lagos, Nigeria. Materials and Methods: A descriptive cross-sectional study was carried out at Ante-natal clinics in Lagos State, Nigeria. About 5 mls of blood was collected into Ethylene Diamine Tetracetic Acid (EDTA) bottles from HIV-negative pregnant women in various gestational ages of pregnancy. CD4+ cell count and full blood count of all samples were done within 3 hours of collection. The descriptive data was given as means ± standard deviation (SD). Pearson's chi-squared test and correlation were used for analytical assessment. Results: A total of 74 pregnant women were recruited. The age range was 19-41 years and a mean age of 30.42 ± 5.34 years. The CD4+ cell count was not statistically significant when compared with participants ages P = 0.417, neither with gestational ages P = 0.323, nor with parity P = 0.247 nor level of education P = 0.96. An overall mean CD4+ cell count was 771.96 ± 250 cells/μl and the range was 193-1370 cells/μl. Conclusion: Maternal age, gestational age, parity and level of education had no significant effects on CD4+ cell count levels in pregnancy. The mean CD4+ cell count of HIV-negative pregnant women in Lagos is 771.96 ± 250 cells/μl

Equatorial F-region irregularities at different seasons in Africa

Trans-ionospheric signals such as the Global Positioning System (GPS) signals propagating through irregular ionospheric plasma structures may experience phase variation and amplitude fades causing degradation in system performance. This paper investigates the latitudinal structure of equatorial F-region irregularities (EFI) in the African region at different seasons using a GPS-based proxy index (rate of change of TEC index (ROTI)). The results obtained indicate the dependence of EFI on local time, season and latitude. Its occurrence time ranges between 19:00 and 0:00LT depending on the season. Its appearance is earlier in equinoxes, particularly in March equinox, and late in June solstice. Further, its occurrence lies generally within �22� magnetic latitudes for all seasons. The probability of occurrence, which is observed to be generally higher in equinoxes than solstices, is almost comparable across the entire latitudes where it was observed in equinoxes while the observations in solstices indicate a dip around the magnetic equator. Furthermore, the average seasonal value of ROTI indicates a clear latitudinal dependence; with appearance within �(0�-12�) magnetic latitude in solstices while it extends up to 18� in equinoxes, particularly in the south. While the hemispheric asymmetry in the average seasonal values is favored by the hemispheric asymmetry of latitudinal TEC profile, the TEC gradient could help delineate the latitude of its peak occurrence. In addition, severe irregularities are mostly observed in equinoxes than in solstices across all latitudes of occurrence and are most pronounced around the crest region mainly in the south. Conversely, moderate irregularities are typically observed in solstices and are most frequent around the magnetic equator and the poleward edge of equatorial ionization anomaly (EIA) region in the northern hemisphere