172 research outputs found

    Wild animals suppress the spread of socially transmitted misinformation

    Get PDF
    Understanding the mechanisms by which information and misinformation spread through groups of individual actors is essential to the prediction of phenomena ranging from coordinated group behaviors to misinformation epidemics. Transmission of information through groups depends on the rules that individuals use to transform the perceived actions of others into their own behaviors. Because it is often not possible to directly infer decision-making strategies in situ, most studies of behavioral spread assume that individuals make decisions by pooling or averaging the actions or behavioral states of neighbors. However, whether individuals may instead adopt more sophisticated strategies that exploit socially transmitted information, while remaining robust to misinformation, is unknown. Here, we study the relationship between individual decision-making and misinformation spread in groups of wild coral reef fish, where misinformation occurs in the form of false alarms that can spread contagiously through groups. Using automated visual field reconstruction of wild animals, we infer the precise sequences of socially transmitted visual stimuli perceived by individuals during decision-making. Our analysis reveals a feature of decision-making essential for controlling misinformation spread: dynamic adjustments in sensitivity to socially transmitted cues. This form of dynamic gain control can be achieved by a simple and biologically widespread decision-making circuit, and it renders individual behavior robust to natural fluctuations in misinformation exposure.</p

    Determination of clothing microclimate volume

    Get PDF
    Human heat transfer depends on the amount of ventilation between the skin and the clothing layers, which in turn depends on the microclimate volume (7). This volume is hard to quantify. The traditional method, developed by Crockford et al. (4) and further in Birnbaum and Crockford (1) and Sullivan et al. (10) utilises a vacuum oversuit to evacuate and measure the quantity of air trapped in the microenvironment. This method is cumbersome and an alternative may be found in a model approach or using 3D whole body scans. Lee and Hong (8) endeavoured to ascertain the relationship between the insulation value of the clothing ensemble and the air volume measured by using phase-shifting moiré topography. They determined the microclimate volume between a manikin and a T-shirt. This technique was time efficient and accurate, but it was not reported if this technique could be used on humans and how the results compared to the traditional technique of microclimate volume measurement. A third technique to estimate the microclimate volume assumes that the body is represented by a series of cylinders. The circumference of each segment is measured with and without clothing, allowing the volume of each to be calculated. The method was adopted from Lotens and Havenith (9) and is fast and simple. It is the purpose of this study to compare the reliability and reproducibility of the vacuum suit method, scanning method and cylinder model to determine microclimate volume

    Dual-time-point FDG PET/CT imaging in prosthetic heart valve endocarditis

    Get PDF
    Purpose: FDG PET/CT has been of increasing interest in the diagnostic workup of prosthetic heart valve endocarditis (PVE). Some reports advocate later imaging time points to improve the diagnostic accuracy for PVE. In this study, we compared standard and late FDG PET/CT images in patients with a clinical suspicion of PVE. Materials and Methods: Fourteen scans in 13 patients referred for FDG PET/CT for suspicion of PVE performed at standard (60 min post injection) and late (150 min post injection) time points were scored based on visual interpretation and semi-quantitatively with SUVmax and target-to-background ratio (TBR, defined as [SUVmax valve/SUVmean blood pool]). Final diagnosis was based on surgical findings in all cases of infection (n = 6) and unremarkable follow-up in all others (n = 8). Results: Late images were more prone to false positive interpretation for both visual and semi-quantitative analyses. Visual analysis of the standard images yielded 1 false negative and 1 false positive result. On the late images, no scans were false negative but 5 scans were false positive. Conclusion: Late FDG PET/CT imaging for PVE seem

    Endothermic salts integrated in impermeable suits do not reduce heat strain during exercise

    Get PDF
    Wearing impermeable garments during work inherently leads to heat strain, even in cold environments [1]. Phase change materials (mainly paraffin’s or salt [4]) may be used as a thermal buffer (e.g. [2]) to reduce initial heat stress. Salts can also be used to absorb sweat, which may enhance the cooling power from the skin. Recently, specific encapsulated salts utilising KSCN (potassium thiocyanate) have been developed that consume energy when the KSCN dissolves in water. The heat consumed when the KSCN (present inside 150 g of capsules containing 60% KSCN salt) dissolves in water is 22410 J (249 J/g * 60% * 150 g). When this solving takes place over a period of 30 minutes, the average power transfer is 12 W. One (1) g of KSCN-containing capsules absorbs close to 1 g of moisture. If we assume that 150 g sweat extra can be evaporated from the skin, this yields an extra cooling power of 182 W for 30 minutes. However this evaporated water from the skin is subsequently absorbed by the KSCN in the capsules. During this absorption from the gas phase, the condensation heat is released to the KSCN salt: about 182 W for 30 minutes. However, we hypothesise that this condensation heat will be partly transferred to the body and partly to the environment [3], providing a net benefit to the body. Thus, the total cooling effect due to the salt capsules is composed of two parts: ‱ The cooling effect of about 12 W due to the heat consumption by the dissolving of the salts in water; ‱ The cooling effect of maximal 182 W, which equals the difference between the evaporative heat and the condensation heat. The latter is generated in the salt capsules that transfer part of the heat to the environment. The overall cooling effect should therefore be in between 12 W and 194 W. The purpose of our study was to test the efficacy of a KSCN-based absorbing salt as a PCM for use within impermeable protective clothing. We tested the PCM during 20 min of moderate exercise in a hot (35°C, 40% relative humidity) environment, and hypothesized that thermal strain would be lower in the PCM compared to the non-PCM condition

    Excited B mesons from the lattice

    Get PDF
    We determine the energies of the excited states of a heavy-light meson QqˉQ\bar{q}, with a static heavy quark and light quark with mass approximately that of the strange quark from both quenched lattices and with dynamical fermions. We are able to explore the energies of orbital excitations up to L=3, the spin-orbit splitting up to L=2 and the first radial excitation. These bsˉb \bar{s} mesons will be very narrow if their mass is less than 5775 MeV -- the BKBK threshold. We investigate this in detail and present evidence that the scalar meson (L=1) will be very narrow and that as many as 6 bsˉb \bar{s} excited states will have energies close to the BKBK threshold and should also be relatively narrow.Comment: 17 pages, 6 ps figure

    Locoregional Failure During and After Short-course Radiotherapy Followed by Chemotherapy and Surgery Compared With Long-course Chemoradiotherapy and Surgery:A 5-Year Follow-up of the RAPIDO Trial

    Get PDF
    OBJECTIVE: To analyze risk and patterns of locoregional failure (LRF) in patients of the RAPIDO trial at 5 years. BACKGROUND: Multimodality treatment improves local control in rectal cancer. Total neoadjuvant treatment (TNT) aims to improve systemic control while local control is maintained. At 3 years, LRF rate was comparable between TNT and chemoradiotherapy in the RAPIDO trial. METHODS: A total of 920 patients were randomized between an experimental (EXP, short-course radiotherapy, chemotherapy, and surgery) and a standard-care group (STD, chemoradiotherapy, surgery, and optional postoperative chemotherapy). LRFs, including early LRF (no resection except for organ preservation/R2 resection) and locoregional recurrence (LRR) after an R0/R1 resection, were analyzed. RESULTS: Totally, 460 EXP and 446 STD patients were eligible. At 5.6 years (median follow-up), LRF was detected in 54/460 (12%) and 36/446 (8%) patients in the EXP and STD groups, respectively ( P =0.07), in which EXP patients were more often treated with 3-dimensional-conformed radiotherapy ( P =0.029). In the EXP group, LRR was detected more often [44/431 (10%) vs. 26/428 (6%); P =0.027], with more often a breached mesorectum (9/44 (21%) vs. 1/26 (4); P =0.048). The EXP treatment, enlarged lateral lymph nodes, positive circumferential resection margin, tumor deposits, and node positivity at pathology were the significant predictors for developing LRR. Location of the LRRs was similar between groups. Overall survival after LRF was comparable [hazard ratio: 0.76 (95% CI, 0.46-1.26); P =0.29]. CONCLUSIONS: The EXP treatment was associated with an increased risk of LRR, whereas the reduction in disease-related treatment failure and distant metastases remained after 5 years. Further refinement of the TNT in rectal cancer is mandated.</p

    Is The Amphibian Tree of Life really fatally flawed?

    Get PDF
    Wiens (2007 , Q. Rev. Biol. 82, 55–56) recently published a severe critique of Frost et al.'s (2006, Bull. Am. Mus. Nat. Hist. 297, 1–370) monographic study of amphibian systematics, concluding that it is “a disaster” and recommending that readers “simply ignore this study”. Beyond the hyperbole, Wiens raised four general objections that he regarded as “fatal flaws”: (1) the sampling design was insufficient for the generic changes made and taxonomic changes were made without including all type species; (2) the nuclear gene most commonly used in amphibian phylogenetics, RAG-1, was not included, nor were the morphological characters that had justified the older taxonomy; (3) the analytical method employed is questionable because equally weighted parsimony “assumes that all characters are evolving at equal rates”; and (4) the results were at times “clearly erroneous”, as evidenced by the inferred non-monophyly of marsupial frogs. In this paper we respond to these criticisms. In brief: (1) the study of Frost et al. did not exist in a vacuum and we discussed our evidence and evidence previously obtained by others that documented the non-monophyletic taxa that we corrected. Beyond that, we agree that all type species should ideally be included, but inclusion of all potentially relevant type species is not feasible in a study of the magnitude of Frost et al. and we contend that this should not prevent progress in the formulation of phylogenetic hypotheses or their application outside of systematics. (2) Rhodopsin, a gene included by Frost et al. is the nuclear gene that is most commonly used in amphibian systematics, not RAG-1. Regardless, ignoring a study because of the absence of a single locus strikes us as unsound practice. With respect to previously hypothesized morphological synapomorphies, Frost et al. provided a lengthy review of the published evidence for all groups, and this was used to inform taxonomic decisions. We noted that confirming and reconciling all morphological transformation series published among previous studies needed to be done, and we included evidence from the only published data set at that time to explicitly code morphological characters (including a number of traditionally applied synapomorphies from adult morphology) across the bulk of the diversity of amphibians (Haas, 2003, Cladistics 19, 23–90). Moreover, the phylogenetic results of the Frost et al. study were largely consistent with previous morphological and molecular studies and where they differed, this was discussed with reference to the weight of evidence. (3) The claim that equally weighted parsimony assumes that all characters are evolving at equal rates has been shown to be false in both analytical and simulation studies. (4) The claimed “strong support” for marsupial frog monophyly is questionable. Several studies have also found marsupial frogs to be non-monophyletic. Wiens et al. (2005, Syst. Biol. 54, 719–748) recovered marsupial frogs as monophyletic, but that result was strongly supported only by Bayesian clade confidence values (which are known to overestimate support) and bootstrap support in his parsimony analysis was < 50%. Further, in a more recent parsimony analysis of an expanded data set that included RAG-1 and the three traditional morphological synapomorphies of marsupial frogs, Wiens et al. (2006, Am. Nat. 168, 579–596) also found them to be non-monophyletic. Although we attempted to apply the rule of monophyly to the naming of taxonomic groups, our phylogenetic results are largely consistent with conventional views even if not with the taxonomy current at the time of our writing. Most of our taxonomic changes addressed examples of non-monophyly that had previously been known or suspected (e.g., the non-monophyly of traditional Hyperoliidae, Microhylidae, Hemiphractinae, Leptodactylidae, Phrynobatrachus , Ranidae, Rana , Bufo ; and the placement of Brachycephalus within “ Eleutherodactylus ”, and Lineatriton within “ Pseudoeurycea ”), and it is troubling that Wiens and others, as evidenced by recent publications, continue to perpetuate recognition of non-monophyletic taxonomic groups that so profoundly misrepresent what is known about amphibian phylogeny. © The Willi Hennig Society 2007.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74688/1/j.1096-0031.2007.00181.x.pd
    • 

    corecore