159 research outputs found

    Compromising building regulations and user expectations in the design of high-rise domestic kitchens

    Get PDF
    Purpose ??? The purpose of this paper is to discuss the significance and relevance of social and habitual behaviours of home occupants to the building design process. It argues that introducing quantitative measures such as daylight level alone may not result in a ???healthy and functional??? kitchen without appreciating or factoring-in the impacts of the social roles and user expectations of kitchens in high-rise and compact urban situations.\ud Design/methodology/approach ??? The study investigated three common types of apartment buildings in Hong Kong. Case studies suggested that it is crucial to include in a design process proper considerations of human behaviours byway of preferred approaches andmodes of living, space usage, and weightings of end-user responses that would influence architectural design in a direct and crucial way.\ud Findings ??? The study noted that daylight quality of a kitchen is perceived by most families to be not as important as building control officials and designers thought it would. Instead, it is found that social and cultural factors are more important parameters for users. The study observed that designers rely on physical and quantitative approaches such as daylight factor, window size and window-to-room area ratio to qualify a design solution and ignore the socio-cultural parameters.\ud Originality/value ??? The paper calls for designers and building control officials to incorporate the study of functionality and socio-cultural preferences of users groups in the building design process. The study envisages that an integrated design methodology would enhance the living environment

    Integrated dopaminergic neuronal model with reduced intracellular processes and inhibitory autoreceptors

    Get PDF
    Dopamine (DA) is an important neurotransmitter for multiple brain functions, and dysfunctions of the dopaminergic system are implicated in neurological and neuropsychiatric disorders. Although the dopaminergic system has been studied at multiple levels, an integrated and efficient computational model that bridges from molecular to neuronal circuit level is still lacking. In this study, the authors aim to develop a realistic yet efficient computational model of a dopaminergic pre‐synaptic terminal. They first systematically perturb the variables/substrates of an established computational model of DA synthesis, release and uptake, and based on their relative dynamical timescales and steady‐state changes, approximate and reduce the model into two versions: one for simulating hourly timescale, and another for millisecond timescale. They show that the original and reduced models exhibit rather similar steady and perturbed states, whereas the reduced models are more computationally efficient and illuminate the underlying key mechanisms. They then incorporate the reduced fast model into a spiking neuronal model that can realistically simulate the spiking behaviour of dopaminergic neurons. In addition, they successfully include autoreceptor‐mediated inhibitory current explicitly in the neuronal model. This integrated computational model provides the first step toward an efficient computational platform for realistic multiscale simulation of dopaminergic systems in in silico neuropharmacology

    Measurement of the scintillation time spectra and pulse-shape discrimination of low-energy beta and nuclear recoils in liquid argon with DEAP-1

    Get PDF
    The DEAP-1 low-background liquid argon detector was used to measure scintillation pulse shapes of electron and nuclear recoil events and to demonstrate the feasibility of pulse-shape discrimination (PSD) down to an electron-equivalent energy of 20 keV. In the surface dataset using a triple-coincidence tag we found the fraction of beta events that are misidentified as nuclear recoils to be <1.4×10−7<1.4\times 10^{-7} (90% C.L.) for energies between 43-86 keVee and for a nuclear recoil acceptance of at least 90%, with 4% systematic uncertainty on the absolute energy scale. The discrimination measurement on surface was limited by nuclear recoils induced by cosmic-ray generated neutrons. This was improved by moving the detector to the SNOLAB underground laboratory, where the reduced background rate allowed the same measurement with only a double-coincidence tag. The combined data set contains 1.23×1081.23\times10^8 events. One of those, in the underground data set, is in the nuclear-recoil region of interest. Taking into account the expected background of 0.48 events coming from random pileup, the resulting upper limit on the electronic recoil contamination is <2.7×10−8<2.7\times10^{-8} (90% C.L.) between 44-89 keVee and for a nuclear recoil acceptance of at least 90%, with 6% systematic uncertainty on the absolute energy scale. We developed a general mathematical framework to describe PSD parameter distributions and used it to build an analytical model of the distributions observed in DEAP-1. Using this model, we project a misidentification fraction of approx. 10−1010^{-10} for an electron-equivalent energy threshold of 15 keV for a detector with 8 PE/keVee light yield. This reduction enables a search for spin-independent scattering of WIMPs from 1000 kg of liquid argon with a WIMP-nucleon cross-section sensitivity of 10−4610^{-46} cm2^2, assuming negligible contribution from nuclear recoil backgrounds.Comment: Accepted for publication in Astroparticle Physic

    Service-oriented Distributed Applications in the Future Internet: The Case for Interaction Paradigm Interoperability

    Get PDF
    International audienceThe essential issue of interoperability in distributed systems is becoming even more pressing in the Future Internet, where complex applications will be composed from extremely heterogeneous systems. Open system integration paradigms, such as service oriented architecture (SOA) and enterprise service bus (ESB), have provided answers to the interoperability requirement. However, when it comes to integrating systems featuring heterogeneous interaction paradigms, such as client-service, publish-subscribe and tuple space, existing solutions are typically ad hoc and partial, applying to specific interaction protocol technologies. In this paper, we introduce an interoperability solution based on abstraction and merging of the common high-level semantics of interaction paradigms, which is sufficiently general and extensible to accommodate many different protocol technologies. We apply this solution to revisit the SOA- and ESB-based integration of heterogeneous distributed systems

    Erratum: "A Gravitational-wave Measurement of the Hubble Constant Following the Second Observing Run of Advanced LIGO and Virgo" (2021, ApJ, 909, 218)

    Get PDF
    [no abstract available
    • 

    corecore