Horizontal positional accuracy of Google Earth's imagery over rural areas: a study case in Tamaulipas, Mexico

Due to the popularity of Google Earth (GE), users commonly assume that it is a credible and accurate source of information. Consequently, GE's imagery is frequently used in scientific and others projects. However, Google states that data available in their geographic products are only approximations and, therefore, their accuracy is not officially documented. In this paper, the horizontal positional accuracy of GE's imagery is assessed by means of comparing coordinates extracted from a rural cadastral database against coordinates extracted from well-defined and inferred check points in GE's imagery. The results suggest that if a large number of well-defined points are extracted from areas of high resolution imagery, GE's imagery over rural areas meets the horizontal accuracy requirements of the ASPRS for the production of "Class 1" 1:20,000 maps. Nonetheless, the results also show that georegistration and large horizontal errors occur in GE's imagery. Consequently, despite its overall horizontal positional accuracy, coordinates extracted from GE's imagery should be used with caution

Early collective expansion: Relativistic hydrodynamics and the transport properties of QCD matter

Relativistic hydrodynamics for ideal and viscous fluids is discussed as a tool to describe relativistic heavy-ion collisions and to extract transport properties of the quark-gluon plasma from experimentally measured hadron momentum spectra.Comment: Review article, 54 pages, 25 figure

Long-term outcomes after first-onset arrhythmia in Fontan physiology

Objectives: Patients living with a Fontan circulation are prone to develop arrhythmias. However, their prognostic impact has been seldom studied. As such, we aimed to determine the incidence and predictors of arrhythmias after the Fontan procedure and the long-term outcomes after the first onset of arrhythmias

Expression of Caveolin-1 Induces Premature Cellular Senescence in Primary Cultures of Murine Fibroblasts: Stress-Induced Premature Senescence Upregulates the Expression of Endogenous Caveolin-1

Caveolae are vesicular invaginations of the plasma membrane. Caveolin-1 is the principal structural component of caveolae in vivo. Several lines of evidence are consistent with the idea that caveolin-1 functions as a “transformation suppressor” protein. In fact, caveolin-1 mRNA and protein expression are lost or reduced during cell transformation by activated oncogenes. Interestingly, the human caveolin-1 gene is localized to a suspected tumor suppressor locus (7q31.1). We have previously demonstrated that overexpression of caveolin-1 arrests mouse embryonic fibroblasts in the G(0)/G(1) phase of the cell cycle through activation of a p53/p21-dependent pathway, indicating a role of caveolin-1 in mediating growth arrest. However, it remains unknown whether overexpression of caveolin-1 promotes cellular senescence in vivo. Here, we demonstrate that mouse embryonic fibroblasts transgenically overexpressing caveolin-1 show: 1) a reduced proliferative lifespan; 2) senescence-like cell morphology; and 3) a senescence-associated increase in β-galactosidase activity. These results indicate for the first time that the expression of caveolin-1 in vivo is sufficient to promote and maintain the senescent phenotype. Subcytotoxic oxidative stress is known to induce premature senescence in diploid fibroblasts. Interestingly, we show that subcytotoxic level of hydrogen peroxide induces premature senescence in NIH 3T3 cells and increases endogenous caveolin-1 expression. Importantly, quercetin and vitamin E, two antioxidant agents, successfully prevent the premature senescent phenotype and the up-regulation of caveolin-1 induced by hydrogen peroxide. Also, we demonstrate that hydrogen peroxide alone, but not in combination with quercetin, stimulates the caveolin-1 promoter activity. Interestingly, premature senescence induced by hydrogen peroxide is greatly reduced in NIH 3T3 cells harboring antisense caveolin-1. Importantly, induction of premature senescence is recovered when caveolin-1 levels are restored. Taken together, these results clearly indicate a central role for caveolin-1 in promoting cellular senescence and they suggest the hypothesis that premature senescence may represent a tumor suppressor function mediated by caveolin-1 in vivo