51 research outputs found
Replication potential and different modes of transmission of West Nile virus in an Indian strain of Culex gelidus Theobald (Diptera: Culicidae) mosquitoes
Background & objectives: Culex gelidus mosquito, an important vector of Japanese encephalitis virus, has shown to transmit West Nile virus (WNV), Kunjin and Murray Valley encephalitis viruses experimentally. An attempt was, therefore, made to study the replication kinetics and vector competence of an Indian strain of Cx. gelidus to WNV.
Methods: Mosquitoes were infected by both intrathoracic inoculation and oral feeding and studied the growth kinetics by determining the virus titre on different days post-infection (PI). Vector competence was studied by determining the presence of WNV in saliva on subsequent days PI. Horizontal transmission was determined by demonstrating infection in infant mice by bite of mosquitoes that were fed on viraemic mice previously. Vertical
transmission was studied by screening progeny derived from infected mosquitoes. Trans-stadial transmission was
determined by screening adult mosquitoes emerged from parenterally inoculated IV instar larvae.
Results: The mosquito replicated WNV to 7log10 TCID50/ml on Day 8 PI and maintained the titre for 14 days. Virus dissemination to legs and salivary glands could be detected, but not to ovaries up to Day 10 PI. The mosquitoes picked up infection from viraemic blood and transmitted successfully to infant mice on subsequent feeding.
Trans-stadial transmission also could be demonstrated. However, vertical transmission could not be demonstrated.
Interpretation & conclusion: The replication potential, maintenance of WNV for prolonged periods and ability to
transmit WNV experimentally makes the mosquito a serious threat to public health especially in the wake of active WNV activity in certain parts of India
On the magnetic stability at the surface in strongly correlated electron systems
The stability of ferromagnetism at the surface at finite temperatures is
investigated within the strongly correlated Hubbard model on a semi-infinite
lattice. Due to the reduced surface coordination number the effective Coulomb
correlation is enhanced at the surface compared to the bulk. Therefore, within
the well-known Stoner-picture of band ferromagnetism one would expect the
magnetic stability at the surface to be enhanced as well. However, by taking
electron correlations into account well beyond the Hartree-Fock (Stoner) level
we find the opposite behavior: As a function of temperature the magnetization
of the surface layer decreases faster than in the bulk. By varying the hopping
integral within the surface layer this behavior becomes even more pronounced. A
reduced hopping integral at the surface tends to destabilize surface
ferromagnetism whereas the magnetic stability gets enhanced by an increased
hopping integral. This behavior represents a pure correlation effect and can be
understood in terms of general arguments which are based on exact results in
the limit of strong Coulomb interaction.Comment: 6 pages, RevTeX, 4 eps figures, accepted (Phys. Rev. B), for related
work and info see http://orion.physik.hu-berlin.d
Influence of Cr and W alloying on the fiber-matrix interfacial shear strength in cast and directionally solidified sapphire NiAl composites
Sapphire-reinforced NiAl matrix composites with chromium or tungsten as alloying additions were synthesized using casting and zone directional solidification (DS) techniques and characterized by a fiber pushout test as well as by microhardness measurements. The sapphire-NiAl(Cr) specimens exhibited an interlayer of Cr rich eutectic at the fiber-matrix interface and a higher interfacial shear strength compared to unalloyed sapphire-NiAl specimens processed under identical conditions. In contrast, the sapphire-NiAl(W) specimens did not show interfacial excess of tungsten rich phases, although the interfacial shear strength was high and comparable to that of sapphire-NiAl(Cr). The postdebond sliding stress was higher in sapphire-NiAl(Cr) than in sapphire-NiAl(W) due to interface enrichment with chromium particles. The matrix microhardness progressively decreased with increasing distance from the interface in both DS NiAl and NiAl(Cr) specimens. The study highlights the potential of casting and DS techniques to improve the toughness and strength of NiAl by designing dual-phase microstructures in NiAl alloys reinforced with sapphire fibers
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