Behind the Zone of Avoidance of the Milky Way: What Can We Restore by Direct and Indirect Methods?

Purpose: to present a brief overview of methods for restoring the large-scale structure of the Universe behind the Zone of Avoidance (ZoA) of the Milky Way; to propose a new “algorithm of darning the ZoA” and new approach based on the Generative adversarial network (GAN) to recover galaxy distribution in the ZoA using optical surveys as an additional platform for programming the artificial neural networks.Предмет и цель работы: представить краткий обзор методов, которые применяются для восстановления распределения крупномасштабных структур Вселенной за зоной избегания (ZoA) Млечного Пути; предложить новый “алгоритм штопки зоны избегания” и новый подход, основанный на Генерирующих состязательных сетях (GAN) для восстановления распределения галактик в ZoA с использованием оптических обзоров в качестве дополнительной платформы для программирования искусственных нейронных сетей.Предмет і мета роботи: подати короткий огляд методів, які застосовуються для відтворення розподілу великомасштабних структур Всесвіту за зоною уникнення (ZoA) Чумацького Шляху;запропонувати новий “алгоритм штопання зони уникнення” і новий підхід, що грунтується на генеруючій змагальній мережі (GAN) для відновлення розподілу галактик в ZoA з використанням оптичних оглядів у якості додаткової платформи для програмування штучних нейронних мереж

EXPERIENCE OF USE OF PNEUMOCOCCAL CONJUGATED 7-VALENT VACCINE IN SOME REGIONS OF RUSSIA

An experience of immunization with pneumococcal conjugated 7-valent vaccine Prevenar in 234 children under 5 years old with different state of health was analyzed. There were no any severe reactions, postvaccinal complications or local reactions to the vaccine injection. Mild and moderate postvaccinal reactions were detected in 3,4% (n = 8) of children. The vaccine can be used in children under 5 years old.Key words: children, vaccination, pneumococcal conjugated 7-valent vaccine, safety.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(2):119-123

Nanostructured polyelectrolyte complexes based on water-soluble thiacalix[4]Arene and pillar[5]arene: Self-assembly in micelleplexes and polyplexes at packaging DNA

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Controlling the self-assembly of polyfunctional compounds in interpolyelectrolyte aggregates is an extremely challenging task. The use of macrocyclic compounds offers new opportunities in design of a new generation of mixed nanoparticles. This approach allows creating aggregates with multivalent molecular recognition, improved binding effciency and selectivity. In this paper, we reported a straightforward approach to the synthesis of interpolyelectrolytes by co-assembling of the thiacalix[4]arene with four negatively charged functional groups on the one side of macrocycle, and pillar[5]arene with 10 ammonium groups located on both sides. Nanostructured polyelectrolyte complexes show effective packaging of high-molecular DNA from calf thymus. The interaction of co-interpolyelectrolytes with the DNA is completely different from the interaction of the pillar[5]arene with the DNA. Two different complexes with DNA, i.e., micelleplex- and polyplex-type, were formed. The DNA in both cases preserved its secondary structure in native B form without distorting helicity. The presented approach provides important advantage for the design of effective biomolecular gene delivery systems

Multi-wavelength properties and SMBH’s masses of the isolated AGNs in the Local Universe

<p>The sample of 36 nearest isolated AGNs was cross-matched by 2MIG and Veron-Cetty catalogues and limited to Ks ≤ 12.0m and Vr < 15 000 km/s in the northern sky (δ ≥ -15°). These objects were in isolation during ~ 3 Gyrs. For revealing their multi-wavelength properties we used all the available databases obtained with ground-based and space observatories (from radio to X-ray ranges). It is allowed us to separate the internal evolution mechanisms from the environment influence and consider them as two separate processes related to fueling nuclear activity and accretion on the SMBHs outside of the environment.<br> In this report we present briefly main results, which were already published (Pulatova N., Vavilova I., Sawangwit U. et al. The 2MIG isolated AGNs - I. General and multiwavelength properties of AGNs and host galaxies in the northern sky, MNRAS, 447, Issue 3, p. 2209-2223 (2015)). We accentuate that for the first time we revealed that the host isolated galaxies with AGNs of Sy1 type (without faint companions) appear to possess the bar morphological features (e.g., the interaction with neighboring galaxies is not necessary condition for broad-line region formation). We give also current results as concerns with more detail X-ray analysis, emission features and spectral models for several AGNs for which a cumulative soft and hard energy spectrum was reconstructed. The estimates of SMBH masses show that are systematically lower than the SMBH masses of AGNs located in a dense environment.</p

Iminodiacetic derivatives of p-tert-butylthiacalix[4]arene: Synthesis and influence of conformation on the aggregation with bismarck brown Y

Three conformers (cone, partial cone and 1,3-alternate) of tetrasubstituted at the lower rim p-tert-butylthiacalix[4] arene derivatives with iminodiacetic fragments were synthesized and characterized. It was shown by spectral methods (UV-Vis,1H NMR and DOSY spectroscopy, DLS) and TEM that the monodisperse nano-sized particles are formed by self-assembly of synthetic octaacids in water with azo dye Bismarck brown Y in the case of the partial cone and 1,3-alternate conformations. It was found that the dye associates with the acid binding sites of the macrocycle. © ISUCT Publishing

Iminodiacetic derivatives of p-tert-butylthiacalix[4]arene: Synthesis and influence of conformation on the aggregation with bismarck brown Y

Three conformers (cone, partial cone and 1,3-alternate) of tetrasubstituted at the lower rim p-tert-butylthiacalix[4] arene derivatives with iminodiacetic fragments were synthesized and characterized. It was shown by spectral methods (UV-Vis,1H NMR and DOSY spectroscopy, DLS) and TEM that the monodisperse nano-sized particles are formed by self-assembly of synthetic octaacids in water with azo dye Bismarck brown Y in the case of the partial cone and 1,3-alternate conformations. It was found that the dye associates with the acid binding sites of the macrocycle. © ISUCT Publishing

2D monomolecular nanosheets based on thiacalixarene derivatives: Synthesis, solid state self-assembly and crystal polymorphism

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Synthetic organic 2D materials are attracting careful attention of researchers due to their excellent functionality in various applications, including storage batteries, catalysis, thermoelectricity, advanced electronics, superconductors, optoelectronics, etc. In this work, thiacalix[4]arene derivatives functionalized by geranyl fragments at the lower rim in cone and 1,3-alternate conformations, that are capable of controlled self-assembly in a 2D nanostructures were synthesized. X-ray diffraction analysis showed the formation of 2D monomolecular-layer nanosheets from synthesized thiacalix[4]arenes, the distance between which depends on the stereoisomer used. It was established by DSC, FSC, and PXRD methods that the obtained macrocycles are capable of forming different crystalline polymorphs, moreover dimethyl sulphoxide (DMSO) is contributing to the formation of a more stable polymorph for cone stereoisomer. The obtained crystalline 2D materials based on synthesized thiacalix[4]arenes can find application in material science and medicine for the development of modern pharmaceuticals and new generation materials