32,114 research outputs found

    A projective Dirac operator on CP^2 within fuzzy geometry

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    We propose an ansatz for the commutative canonical spin_c Dirac operator on CP^2 in a global geometric approach using the right invariant (left action-) induced vector fields from SU(3). This ansatz is suitable for noncommutative generalisation within the framework of fuzzy geometry. Along the way we identify the physical spinors and construct the canonical spin_c bundle in this formulation. The chirality operator is also given in two equivalent forms. Finally, using representation theory we obtain the eigenspinors and calculate the full spectrum. We use an argument from the fuzzy complex projective space CP^2_F based on the fuzzy analogue of the unprojected spin_c bundle to show that our commutative projected spin_c bundle has the correct SU(3)-representation content.Comment: reduced to 27 pages, minor corrections, minor improvements, typos correcte

    A comparison of two computational methods (RANS and LES) in analysing of ventilation flow through a room fitted with a two-sided windcatcher for free flow condition

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    A windcatcher is a structure for providing natural ventilation using wind power; it is usually fitted on the roof of a building to exhaust the inside stale air to the outside and supplies the outside fresh air into the building interior space working by pressure difference between outside and inside of the building. In this paper, the behaviour of free wind flow through a three-dimensional room fitted with a centred position two-canal bottom shape windcatcher model is investigated numerically, using a commercial computational fluid dynamics (CFD) software package and LES (Large Eddy Simulation) CFD method. The results have been compared with the obtained results for the same model but using RANS (Reynolds Averaged Navier-Stokes) CFD method. The model with its surrounded space has been considered in both method. It is found that the achieved results for the model from LES method are in good agreement with RANS method’s results for the same model

    ICCM2015: A Comparison of RANS and LES Computational Methods in Analyzing Ventilation Flow Through a Room Fitted with a Two-Sided Windcatcher

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    A windcatcher is a structure for providing natural ventilation using wind power; it is usually fitted on the roof of a building to exhaust the inside stale air to the outside and supplies the outside fresh air into the building interior space working by pressure difference between outside and inside of the building. In this paper, the behaviour of free wind flow through a three-dimensional room fitted with a centred position two-canal bottom shape windcatcher model is investigated numerically, using a commercial computational fluid dynamics (CFD) software package and LES (Large Eddy Simulation) CFD method. The results have been compared with the obtained results for the same model but using RANS (Reynolds Averaged Navier-Stokes) CFD method. The model with its surrounded space has been considered in both method. It is found that the achieved results for the model from LES method are in good agreement with RANS method’s results for the same model

    Immunopathogenesis of canine chronic ulcerative stomatitis.

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    Canine Chronic Ulcerative Stomatitis is a spontaneously occurring inflammatory disease of the oral mucosa. An immune-mediated pathogenesis is suspected though not yet proven. We have recently reported on the clinical and histologic features, and identification of select leukocyte cell populations within the lesion. A clinical and histologic similarity to oral lichen planus of people was proposed. In the present study, these initial observations are extended by examining lesions from 24 dogs with clinical evidence of chronic ulcerative stomatitis. Because dogs with chronic ulcerative stomatitis often have concurrent periodontal disease, we wondered if dental plaque/biofilm may be a common instigator of inflammation in both lesions. We hypothesized that dogs with chronic ulcerative stomatitis would exhibit a spectrum of pathologic changes and phenotype of infiltrating leukocytes that would inform lesion pathogenesis and that these changes would differ from inflammatory phenotypes in periodontitis. Previously we identified chronic ulcerative stomatitis lesions to be rich in FoxP3+ and IL17+ cells. As such, we suspect that these leukocytes play an important role in lesion pathogenesis. The current study confirms the presence of moderate to large numbers of FoxP3+ T cells and IL17+ cells in all ulcerative stomatitis lesions using confocal immunofluorescence. Interestingly, the majority of IL17+ cells were determined to be non-T cells and IL17+ cell frequencies were negatively correlated with severity on the clinical scoring system. Three histologic subtypes of ulcerative stomatitis were determined; lichenoid, deep stomatitis and granulomatous. Periodontitis lesions, like stomatitis lesions, were B cell and plasma cell rich, but otherwise differed from the stomatitis lesions. Direct immunofluorescence results did not support an autoantibody-mediated autoimmune disease process. This investigation contributes to the body of literature regarding leukocyte involvement in canine idiopathic inflammatory disease pathogenesis

    Distributed simulation and industry: Potentials and pitfalls

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    We present the views of five researchers and practitioners of distributed simulation. Collectively we attempt to address what the implications of distributed simulation are for industry. It is hoped that the views contained herein, and the presentations made by the panelists at the 2002 Winter Simulation Conference will raise awareness and stimulate further discussion on the application of distributed simulation methods and technology in an area that is yet to benefit from the arguable economic benefits that this technique promises

    A clinical trial combining donor bone marrow infusion and heart transplantation: intermediate-term results.

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    BACKGROUND: Donor chimerism (the presence of donor cells of bone marrow origin) is present for years after transplantation in recipients of solid organs. In lung recipients, chimerism is associated with a lower incidence of chronic rejection. To augment donor chimerism with the aim to enhance graft acceptance and to reduce immunosuppression, we initiated a trial combining infusion of donor bone marrow with heart transplantation. Reported herein are the intermediate-term results of this ongoing trial. METHODS: Between September 1993 and August 1998, 28 patients received concurrent heart transplantation and infusion of donor bone marrow at 3.0 x 10(8) cells/kg (study group). Twenty-four contemporaneous heart recipients who did not receive bone marrow served as controls. All patients received an immunosuppressive regimen consisting of tacrolimus and steroids. RESULTS: Patient survival was similar between the study and control groups (86% and 87% at 3 years, respectively). However, the proportion of patients free from grade 3A rejection was higher in the study group (64% at 6 months) than in the control group (40%; P =.03). The prevalence of coronary artery disease was similar between the two groups (freedom from disease at 3 years was 78% in study patients and 69% in controls). Similar proportions of study (18%) and control (15%) patients exhibited in vitro evidence of donor-specific hyporesponsiveness. CONCLUSIONS: The infusion of donor bone marrow reduces the rate of acute rejection in heart recipients. Donor bone marrow may play an important role in strategies aiming to enhance the graft acceptance

    Antimicrobial and cytotoxic activity of Streptomyces sp. from Lonar Lake

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    Antibacterial substances from actinomycetes were isolated from marine environment of Lonar Lake and characterized. Out of the 24 isolates subjected to secondary screening, 12 isolates were active againstBacillus subtilis, 13 against Staphylococcus aureus, 7 against Escherichia coli, 3 against Proteus vulgaris and 4 against Salmonella typhi. Metabolites in the extract of broth of 48 hrgrown Streptomyces spp. culture no.2 proved to have antimicrobial and cytotoxic against human lung carcinoma cell A549
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