Ecological and geographical confinement of rare medicinal plants of forest flora of the Kuznetski Alatau in need of protection

The subject of the study was rare medicinal plants of the forest flora of the Kuznetski Alatau. The species used in officinal, folk and homeopathic medicine were listed as medicinal plants. The list of rare medicinal plants of forest flora of the Kuznetski Alatau in need of protection is recommended on the basis of field research conducted by the author. There are 12 species in the list. The method of regular embedding of key areas and a network of expeditionary routes were used in order to select field data, which enables a reliable estimation of the floristic richness of forest flora of the studied region. Identification of rare species was based on their occurrence and abundance. The basis for ecological and geographical analysis was the assignment of each species by the confinement of its belt and zone to a particular ecological-geographical group. The basis of chronological analysis was assigning each species to a specific geographical group according to a character of areal. The distribution within the Kuznetski Alatau inside geobotanical districts is shown for each species. Endemic and relicts are indicated. Nemoral elements, which are rare in the forests of the Kuznetski Alatau, are attributed to relicts of coniferous-deciduous forests. A complex coenotic character of the studied spectrum of flora, due to substantial participation of species, confined to light coniferous, deciduous and dark coniferous forests, was found. However, the proportion of species of dark coniferous plant communities is considerably inferior to the participation of species associated with cenoses of coniferous and deciduous forests. These exact species are more plastic coenotically and environmentally and they represent the majority of additional, natural mountainous and additional mountainous species

On the formation of skills of speech at the research and practical conference in foreign (English) language on the professional subject of bachelors and masters of non-language universities

At the Institute of Applied Mathematics and Computer Science of National Research Tomsk State University, annually for twenty years a scientific and practical student conference is held. The main purpose of this conference is to provide an opportunity for future specialists to implement the skills and abilities of practical language skills in situations of foreign language professional and scientific communication, namely to make reports in a foreign language, to discuss topics related to the scientific work of the conference participants. Teachers of the department of the English language of natural science and physics and mathematics faculties take an active part in organizing the conference; prepare bachelors and masters for presentation with reports in English. The article considers the method of training bachelors and masters to speak with their project in English at a research and practical conference in a non-language university and the role of the English language teacher in the developing of skills of speech at the conference at each stage of preparation. Many years method of preparing students to speak at a research and practical conference in a foreign language (English) at this Institute shows positive results. Students adequately present their scientific reports, showing a confident knowledge of English as a means of professional communication, thereby increasing the motivation for further improvement of English language for professional purposes

SOCIALIZAÇÃO DE FUTUROS ESPECIALISTAS NO CONTEXTO DA ABORDAGEM POR COMPETÊNCIAS

The solution of the problems facing the modern Russian society largely depends on the beliefs, expectations, values and attitudes of people that determine their attitude to innovation, content, effectiveness and efficiency of various activities. Social adaptation (active inclusion in the social environment) of the individual assumes as a necessary condition the achievement of a certain level of social competence. The modern social environment has a significant impact on the process of personality formation, causing certain contradictions: on the one hand, socio-cultural modernization necessitates a new approach to the problem of social self-realization of the individual, requiring increased human activity as a subject of social life, taking responsibility for their activities and behavior, but, on the other hand, the instability of modern society increases the natural difficulties of growing up; the situation of uncertainty leads to deformation of personal development, disadaptation in society. Modernization of the education system has led to changes in the content, forms, methods and technologies of education, in connection with which there was a need to assess the results of the functioning of the education system. Analyzing the quality of a modern specialist training, researchers increasingly began to turn to the competencies formed during studying, among which an important place is occupied by social competence, estimated as the most important indicator of professional competence of a specialist in general, and in particular, in the field of economic, labor, social relations.A solução dos problemas enfrentados pela sociedade russa moderna depende em grande parte das crenças, expectativas, valores e atitudes das pessoas que determinam sua atitude em relação à inovação, conteúdo, eficácia e eficiência de várias atividades. A adaptação social (inclusão ativa no ambiente social) do indivíduo assume como condição necessária a conquista de um certo nível de competência social. O ambiente social moderno tem um impacto significativo no processo de formação da personalidade, causando certas contradições: por um lado, a modernização sociocultural requer uma nova abordagem para o problema da auto- realização social do indivíduo, exigindo maior atividade humana como sujeito da vida social, assumindo a responsabilidade por suas atividades e comportamentos, mas, por outro lado, a instabilidade da sociedade moderna aumenta as dificuldades naturais de crescer; a situação de incerteza leva à deformação do desenvolvimento pessoal, à desadaptação na sociedade. A modernização do sistema educacional levou a mudanças no conteúdo, formas, métodos e tecnologias da educação, em relação às quais havia a necessidade de avaliar os resultados do funcionamento do sistema educacional. Analisando a qualidade de um treinamento especializado moderno, os pesquisadores começaram a recorrer cada vez mais às competências formadas durante o estudo, entre as quais um lugar importante é ocupado pela competência social, estimado como o indicador mais importante da competência profissional de um especialista em geral e, em particular, , no campo das relações econômicas, trabalhistas e sociais.La solución de los problemas que enfrenta la sociedad rusa moderna depende en gran medida de las creencias, expectativas, valores y actitudes de las personas que determinan su actitud hacia la innovación, el contenido, la efectividad y la eficiencia de diversas actividades. La adaptación social (inclusión activa en el entorno social) del individuo supone como condición necesaria el logro de un cierto nivel de competencia social. El entorno social moderno tiene un impacto significativo en el proceso de formación de la personalidad, causando ciertas contradicciones: por un lado, la modernización sociocultural requiere un nuevo enfoque del problema de la autorrealización social del individuo, que requiere una mayor actividad humana como un sujeto de la vida social, asumiendo la responsabilidad de sus actividades y comportamiento, pero, por otro lado, la inestabilidad de la sociedad moderna aumenta las dificultades naturales de crecer; La situación de incertidumbre conduce a la deformación del desarrollo personal, la desadaptación en la sociedad. La modernización del sistema educativo ha llevado a cambios en el contenido, las formas, los métodos y las tecnologías de la educación, en relación con lo cual era necesario evaluar los resultados del funcionamiento del sistema educativo. Analizando la calidad de una formación especializada moderna, los investigadores comenzaron a recurrir cada vez más a las competencias formadas durante el estudio, entre las cuales un lugar importante está ocupado por la competencia social, estimado como el indicador más importante de la competencia profesional de un especialista en general, y en particular , en el campo de las relaciones económicas, laborales, sociales

ROLE OF INFORMAL ASSESSMENT IN IMPROVING STUDENTS` REFLECTION

Purpose. The article is devoted to various methods of informal assessment and their potential for developing students’ reflective skills. The authors analyze different theories and approaches to reflective learning in order to design tools for enhancing students’ reflective abilities. Methodology. The data obtained through the research are evaluated and interpreted on the basis of the descriptive approach. The authors also adopt the reflective-activity approach for designing a set of reflective statements. Results. The authors study the main features of informal assessment, compare and contrast them with the forms of formal assessment pointing out that new approaches to assessment such as Learning Oriented Assessment (LOA) should be adopted in order to promote learning, motivate students and encourage their autonomy. Special attention is given to feedback as an LOA component, which correlates with the concept of reflective learning. The authors analyze various theories of reflective learning and design a system of reflective statement, which could be used as a means of practical development of students’ reflective abilities. Practical implications. The results of the research can be applied in teaching practice of various disciplines at higher educational establishments

Analysis of catalysts by spectrophotometry with partial least-squares method

Введение. Многие переходные металлы, входящие в состав катализаторов, способны образовывать окрашенные комплексы, и спектрофотометрия могла бы стать удобным и недорогим методом оценки их содержания. Но из-за сильного перекрывания спектров такие методики практически не применяют в анализе катализаторов. Расширить возможности спектрофотометрии можно за счет перехода к многоволновому варианту анализа в сочетании с хемометрической обработкой спектров. Цель работы - показать возможность применения спектрофотометрии в сочетании с методом проекции на латентные структуры (PLS) для определения металлов в нанесенных катализаторах по реакциям комплексообразования с неселективным реагентом 4-(2 пиридилазо)резорцином (ПАР). Объекты анализа - Pd-Ga катализаторы на основе оксида алюминия и сибунита, а также модельная сухая смесь состава PdO-Re₂O₇/ZrO₂-Al₂O₃-Na₂SO₄. Эксперимент. Катализаторы и сухие модельные смеси, содержащие один или несколько металлов, разлагали в кислотах; полученные растворы анализировали методом атомно-эмиссионной спектрометрии с индуктивно-связанной плазмой (АЭС-ИСП), а также спектрофотометрическим методом до и после прибавления к ним реагента ПАР. Результаты. Показана возможность раздельного спектрофотометрического определения 1-4 металлов, как по собственному поглощению, так и с использованием ПАР. В случае определения нескольких металлов обработку спектральной информации вели методом PLS. PLS-градуировка построена по спектрам поглощения растворов реальных проб катализаторов с использованием данных о содержании компонентов, полученных методом АЭС-ИСП. Такой подход позволил учесть влияние матрицы и определять в катализаторах металлы с погрешностями 1-5 % отн. и относительным стандартным отклонением от 0.01 до 0.06, что сопоставимо по точности с методом АЭС-ИСП.Introduction. Many transition metals that make up catalysts are capable of forming colored complexes, and spectrophotometry could be a convenient and inexpensive method to estimate their content. However, such techniques are not widely applied in the analysis of catalysts because of the strong overlapping spectra. Multi wave analysis in combination with the chemometric treatment of the spectra can extend the capabilities of the spectrophotometry. The purpose of the experiment reported here was to show the possibility of applying spectrophotometry in combination with the partial least-squares method (PLS) to determine metals in catalysts by reactions of complex formations. It was proposed to use a non-selective reagent 4 (2 pyridylazo) resorcinol (PAR). Experimental Procedures. Catalysts and dry model mixtures containing one or more metals were decomposed by acids. Spectra of the resulting solutions and spectra of the solutions after adding the above mentioned PAR reagent were recorded. The resulting solutions were also analyzed using the reference method of atomic emission spectroscopy (AES). Results. The possibility to separately determine from 1 to 4 metals by spectrophotometry both on their own absorption in the UV region and using PAR reagent was shown. In the case of determination of several metals the partial least-squares method (PLS) was utilized for processing the spectral information. To construct the PLS-calibration for the first time, the absorption spectra of the real samples of catalysts in combination with data obtained by atomic emission spectroscopy method (AES) was used. This approach allowed considering the influence of the matrix and quantifying metals in catalysts with errors of 1-5%, and with the relative standard deviation of 0.01 to 0.06, which is comparable in accuracy to the AES method

INFLUENCE OF RENAL DYSFUNCTION ON THE LEVEL OF SERUM ANGIOPOIETIN-LIKE PROTEINS AND ANTI-PHOSPHOLIPID ANTIBODIES IN PATIENTS WITH RHEUMATOID ARTHRITIS AND METABOLIC SYNDROME

Rheumatoid arthritis (RA) is a frequent background for the development of renal pathology. Chronic kidney disease (CKD) is determined in more than 30% of patients with RA. Along with inflammation and other factors in the progression of the underlying disease, the development of renal damage in RA is facilitated by the presence of metabolic syndrome (MetS).The aim of this study is to assess the relationship of serum concentrations of angiopoietin-like proteins (ANGPTL) and antiphospholipid antibodies (aPL) with the development of renal dysfunction in patients with RA.We examined 158 patients with RA (91.8% – women and 8.2% – men) aged 21 to 80 years old and an average duration of the disease – 9 (4-15) years. The majority of patients were seropositive for rheumatoid factor and for antibodies to cyclic citrullinated peptide, with an advanced clinical stage and moderate activity (3.2 < DAS28 ≤ 5.1) of the pathological process.The ELISA test was used for the quantitative determination of angiopoietin-like protein type 3 and type 4 and antibodies to phospholipids (aРL-IgG/IgM) for total detection of antibodies to cardiolipin, phosphatidylserine, phosphatidylinositol, phosphatidylic acid and a complex of negatively charged phospholipid and β2-glycoprotein-I.More than half of the examined RA patients had the calculated glomerular filtration rate (eGFR) ranging from 89 to 60 ml/min/1.73 m2 (allocation by CKD stages: C1 – 21.5%; C2 – 58.9%; C3 – 19.6%). Signs of MetS (a combination of increased blood pressure, increased triglyceride levels and carbohydrate metabolism disorders against the background of central obesity) were diagnosed in 68 (43%) RA patients. Multivariable analysis of variance was performed to compare the studied parameters (ANGPTL3, ANGPTL4, aPL) depending on eGFR in groups of RA patients without signs of metabolic syndrome and RA patients with MetS. Significant differences in the level of ANGPTL3 (F = 8.86, p = 0.0034) and ANGPTL4 (F = 29.6, p < 0.001), but not aPL (p > 0,05) were found between RA patients with varying degrees of severity of metabolic disorders.Multivariable analysis of variance showed a significant increase in ANGPTL4 in the blood serum of RA patients with reduced eGFR (< 89 ml/min) (F = 18.5, p < 0.001) and pronounced metabolic changes (F = 24.2, p < 0.001). Thus, only two factors (renal dysfunction and the presence of MetS) had a direct effect on the ANGPTL4 content in RA patients, which could describe the variability of this sign in more than 30% of cases. The squared multiple correlation coefficient (R2 ) in this model was 0.33. ANGPTL type 4 should be considered as a key factor linking the development of renal dysfunction and metabolic changes caused by rheumatoid inflammation

Environmental monitoring of natural waters in Krasnodar and Stavropol Territories

The environmental monitoring of natural waters in Krasnodar (Uspensky and Novokubansky districts) and Stavropol (Kochubeyevsky District) Territories was conducted. In the course of study, various elements and compounds harmful to animals and humans, which exceed maximum permissible concentrations, were identified

Impact of transfusion of blood components on the recipient immune system

Transfusions of blood provide essential therapeutic measures in a number of pathological conditions. However, when carrying out blood component therapy, it is important to consider probability of post-transfusion complications. Most of them are immune-mediated side effects. The unfavorable consequences of blood transfusions can manifest at long-range time periods, and pathogenesis of these phenomena may be associated not only with the presence of alloantibodies. They may be caused by alloimmunization to HLA antigens, leukocyte factors, including cytokines, products of leukocyte degranulation, as well as storage-related erythrocyte damage («storage lesion»), immunomodulatory properties of extracellular vesicles or microparticles derived from blood components, and other factors. Despite significant number of publications on this issue, a lot of unresolved issues still remain, concerning transfusion-related effects of blood components on the immune system of recipients. The review article provides the results of current studies in this area. We present and discuss the results of current studies and the features of transfusion-mediated immunomodulation (TRIM) revealed over recent years, when transfusing different blood components. The role of plasma factors, microparticles, platelets and erythrocytes, HLA sensitization and microchimerism in the development of TRIM is highlighted, the data on occurrence and clinical features of TRIM in perioperative period are presented. A separate section of the review provides information about recent clinical studies, devoted to the issues of TRIM in different clinical cohorts, including newborns, patients with malignant neoplasms, immunocompromised patients after heart and vascular surgery. The data on TRIM incidence in the patients with exhausted immune system due to previous disease or treatment, severe comorbidity, extensive surgical thoracic/abdominal intervention and artificial circulation are also in scope. As based on the studies performed, the role of distinct measures, e.g., washing of erythrocyte concentrates, leukodepletion, and gamma irradiation are discussed in view of potential TRIM prevention. The results of published research do not allow us to draw definite conclusions about the effects of blood component transfusion on the immune system of recipients with respect to differences between the studied groups of patients, characteristics of the studied disorders and clinical situations, diversity of hemocomponents, as well as varying standards of transfusion therapy adopted in different countries. However, the systematic literature review may provide some guidance in transfusion-mediated immune modulation