45 research outputs found
Lax-Phillips scattering theory for PT-symmetric \rho-perturbed operators
The S-matrices corresponding to PT-symmetric \rho-perturbed operators are
defined and calculated by means of an approach based on an operator-theoretical
interpretation of the Lax-Phillips scattering theory
Approximate resonance states in the semigroup decomposition of resonance evolution
The semigroup decomposition formalism makes use of the functional model for
class contractive semigroups for the description of the time evolution
of resonances. For a given scattering problem the formalism allows for the
association of a definite Hilbert space state with a scattering resonance. This
state defines a decomposition of matrix elements of the evolution into a term
evolving according to a semigroup law and a background term. We discuss the
case of multiple resonances and give a bound on the size of the background
term. As an example we treat a simple problem of scattering from a square
barrier potential on the half-line.Comment: LaTex 22 pages 3 figure
On operators of transition in Krein spaces
Abstract. The paper is devoted to investigation of operators of transition and the corresponding decompositions of Krein spaces. The obtained results are applied to the study of relationship between solutions of operator Riccati equations and properties of the associated operator matrix L. In this way, we complete the known result (see Theorem 5.2 in the paper of S. Albeverio, A. Motovilov, A. Skhalikov, Integral Equ. Oper. Theory 6
-self-adjoint operators with -symmetries: extension theory approach
A well known tool in conventional (von Neumann) quantum mechanics is the
self-adjoint extension technique for symmetric operators. It is used, e.g., for
the construction of Dirac-Hermitian Hamiltonians with point-interaction
potentials. Here we reshape this technique to allow for the construction of
pseudo-Hermitian (-self-adjoint) Hamiltonians with complex
point-interactions. We demonstrate that the resulting Hamiltonians are
bijectively related with so called hypermaximal neutral subspaces of the defect
Krein space of the symmetric operator. This symmetric operator is allowed to
have arbitrary but equal deficiency indices . General properties of the
$\cC$ operators for these Hamiltonians are derived. A detailed study of
$\cC$-operator parametrizations and Krein type resolvent formulas is provided
for $J$-self-adjoint extensions of symmetric operators with deficiency indices
. The technique is exemplified on 1D pseudo-Hermitian Schr\"odinger and
Dirac Hamiltonians with complex point-interaction potentials
Arrhythmic Mitral Valve Prolapse: New Menaces of the Known Disease
Mitral valve prolapse (MVP) has long been the subject of intense discussions regarding the prognosis and follow-up tactics. In most cases, this condition has a benign prognosis. However, recent autopsy and follow-up studies have shown risks of developing sudden cardiac death (SCD) in some subgroups of patients who have this clinical phenomenon. The proposed literature review uses the population of patients with MVP with the highest probability of developing life-threatening ventricular tachyarrhythmias. Patients with the presence of a complex of changes, including bicuspid MVP, negative T waves in the inferior and lateral leads on a standard 12-lead electrocardiogram (ECG), and a special anatomical phenomenon called mitral annular disjunction (MAD), are at high risk of developing ventricular ectopias and VSS. A reflection of the high risk of SCD in such patients is the increase of ventricular ectopy according to Holter monitoring. The presence of a bicuspid MVP and the MAD phenomenon, which is a separation of the line of attachment of the posterior mitral leaflet from the basal inferior wall segment towards the atrial wall, determines the presence of a special form of MVP, the so-called arrhythmogenic MVP. Hence, in most cases MVP has a benign prognosis. However, patients with the aforementioned ar- rhythmic MVP signs must be given particular attention and annual follow-up including ECG control, Holter monitoring and echocardiographic examination of the heart to reduce the risk of ventricular tachyarrhythmias and SCD development
SAFETY OF AMIODARONE USAGE IN PATIENTS WITH WOLFF-PARKINSON-WHITE SYNDROME AND ATRIAL FIBRILLATION
Amiodarone is one of the basic antiarrhytmic drugs for atrial fibrillation treatment. However application of amiodarone in patients with atrial fibrillation and Wolff-Parkinson-White syndrome can induce ventricular fibrillation. Amiodarone usage in these patients should be accompanied by readiness for performance of resuscitation. This is confirmed by clinical case presentation
On the similarity of Sturm-Liouville operators with non-Hermitian boundary conditions to self-adjoint and normal operators
We consider one-dimensional Schroedinger-type operators in a bounded interval
with non-self-adjoint Robin-type boundary conditions. It is well known that
such operators are generically conjugate to normal operators via a similarity
transformation. Motivated by recent interests in quasi-Hermitian Hamiltonians
in quantum mechanics, we study properties of the transformations in detail. We
show that they can be expressed as the sum of the identity and an integral
Hilbert-Schmidt operator. In the case of parity and time reversal boundary
conditions, we establish closed integral-type formulae for the similarity
transformations, derive the similar self-adjoint operator and also find the
associated "charge conjugation" operator, which plays the role of fundamental
symmetry in a Krein-space reformulation of the problem.Comment: 27 page
Клинико-экономическая оценка эффективности и безопасности существующей практики проведения периоперационной антибиотикопрофилактики на оcнове фармакоэпидемиологического исследования в многопрофильных стационарах Санкт-Петербурга
A survey conducted in four hospitals located in the city of St. Petersburg revealed that the commonly used perioperative antibiotic prophylaxis (PAP) did not follow (in 88% of cases) the guidelines approved for national clinical practice.Aim. To perform a cost-effectiveness analysis of the commonly practiced PAP among patients with clean, clean-contaminated and contaminated surgical wounds in a multidisciplinary hospital.Materials and methods. The PAP cost-effectiveness analysis was performed using the data from a multicenter epidemiological survey and previously conducted studies. The Markov model was used to compare the effectiveness and safety of the commonly used PAP with that recommended by the clinical practice guidelines. The rate of surgical site infection (SSI) and antibiotic-associated diarrhea (AAD) were chosen for the endpoints.Results. The costs associated with a single case of PAP according to the clinical practice guidelines was 3.5 times less than that associated with the PAP used in the common practice (RUB 4913,67 and 17837,71 respectively). The present analysis demonstrates that the PAP recommended by the clinical practice guidelines was more cost-effective as compared with the commonly practiced PAP.Conclusion. Regular epidemiological monitoring is required to improve effectiveness and safety of the existing PAP practice. Целью исследования является клинико-экономическая оценка эффективности и безопасности существующей практики назначения периоперационной антибиотикопрофилактики.Материалы и методы. На основании данных фармакоэпидемиологического исследования, проведенного в четырех многопрофильных стационарах г. Санкт-Петербурга, оценена реальная практика проведения периоперационной антибиотикопрофилактики (ПАП) инфекций области хирургического вмешательства (ИОХВ), которая в абсолютном большинстве случаев (88%) не соответствовала клиническим рекомендациям. Построена модель анализа решений относительно эффективности и безопасности ПАП в реальной практике в сравнении с ПАП в соответствии с клиническими рекомендациями. В качестве критериев эффективности выбраны частота ИОХВ и число случаев предотвращенной антибиотик-ассоциированной диареи (ААД). Проведен анализ «затраты-эффективность».Результаты. Стоимость одного случая ПАП, проведенной по протоколу, с учетом прямых и непрямых затрат меньше таковой, используемой в реальной практике, более чем в 3,5 раза (4913,67 руб. и 17837,71 руб., соответственно). Анализ «затраты-эффективность» показал, что стратегия применения ПАП по протоколу доминировала перед стратегией проведения ПАП в реальной практике: при меньших затратах она имела наибольший прирост эффективности.Выводы. Для оптимизации потребления АМП с целью ПАП в каждом стационаре необходим периодический фармакоэпидемиологический мониторинг существующей практики проведения ПАП. Соблюдение основных принципов ПАП наряду с мерами инфекционного контроля является одной из возможностей минимизировать затраты, связанные с ее неэффективностью.