54 research outputs found
Competition of Mesoscales and Crossover to Tricriticality in Polymer Solutions
We show that the approach to asymptotic fluctuation-induced critical behavior
in polymer solutions is governed by a competition between a correlation length
diverging at the critical point and an additional mesoscopic length-scale, the
radius of gyration. Accurate light-scattering experiments on polystyrene
solutions in cyclohexane with polymer molecular weights ranging from 200,000 up
to 11.4 million clearly demonstrate a crossover between two universal regimes:
a regime with Ising asymptotic critical behavior, where the correlation length
prevails, and a regime with tricritical theta-point behavior determined by a
mesoscopic polymer-chain length.Comment: 4 pages in RevTeX with 4 figure
Probing structural relaxation in complex fluids by critical fluctuations
Complex fluids, such as polymer solutions and blends, colloids and gels, are
of growing interest in fundamental and applied soft-condensed-matter science. A
common feature of all such systems is the presence of a mesoscopic structural
length scale intermediate between atomic and macroscopic scales. This
mesoscopic structure of complex fluids is often fragile and sensitive to
external perturbations. Complex fluids are frequently viscoelastic (showing a
combination of viscous and elastic behaviour) with their dynamic response
depending on the time and length scales. Recently, non-invasive methods to
infer the rheological response of complex fluids have gained popularity through
the technique of microrheology, where the diffusion of probe spheres in a
viscoelastic fluid is monitored with the aid of light scattering or microscopy.
Here we propose an alternative to traditional microrheology that does not
require doping of probe particles in the fluid (which can sometimes drastically
alter the molecular environment). Instead, our proposed method makes use of the
phenomenon of "avoided crossing" between modes associated with the structural
relaxation and critical fluctuations that are spontaneously generated in the
system.Comment: 4 pages, 4 figure
Early postoperative MRI overestimates residual tumour after resection of gliomas with no or minimal enhancement
Standards for residual tumour measurement after resection of gliomas with no or minimal enhancement have not yet been established. In this study residual volumes on early and late postoperative T2-/FLAIR-weighted MRI are compared. A retrospective cohort included 58 consecutive glioma patients with no or minimal preoperative gadolinium enhancement. Inclusion criteria were first-time resection between 2007 and 2009 with a T2-/FLAIR-based target volume and availability of preoperative, early (<48 h) and late (1-7 months) postoperative MRI. The volumes of non-enhancing T2/FLAIR tissue and diffusion restriction areas were measured. Residual tumour volumes were 22% smaller on late postoperative compared with early postoperative T2-weighted MRI and 49% smaller for FLAIR-weighted imaging. Postoperative restricted diffusion volume correlated with the difference between early and late postoperative FLAIR volumes and with the difference between T2 and FLAIR volumes on early postoperative MRI. We observed a systematic and substantial overestimation of residual non-enhancing volume on MRI within 48 h of resection compared with months postoperatively, in particular for FLAIR imaging. Resection-induced ischaemia contributes to this overestimation, as may other operative effects. This indicates that early postoperative MRI is less reliable to determine the extent of non-enhancing residual glioma and restricted diffusion volumes are imperativ
Facial emotion recognition deficits and alexithymia in borderline, narcissistic, and histrionic personality disorders.
Previous studies that aimed to support emotion recognition deficits and alexithymia in B cluster personality disorders have mainly focused on borderline personality disorder (BPD), and resulted in mixed findings. In our study we examine emotion recognition and alexithymia in patients with histrionic (HPD), narcissistic (NPD) and borderline (BPD) personality disorders compared to each other and healthy controls. Furthermore, the possibility is investigated that it is not the type of PD but the severity of psychopathology which predicts the severity of emotion recognition deficits and alexithymia. Patients with HPD, NPD, BPD and healthy controls (N=20 for each group) were examined by using the Ekman 60 Faces Test (FEEST) and the Toronto Alexithymia Scale (TAS-20). To measure the extent and severity of psychopathology, the Symptom-Checklist-90 Revised (SCL-90-R) was used. Patient groups performed significantly worse compared to healthy controls on the Ekman test and TAS-20, while we found no significant differences among patient groups in emotion recognition and alexithymia. Furthermore, higher scores on the SCL-90-R predicted poorer emotion recognition performance and higher alexithymic features. The empirical data supports the conclusion that the severity of psychopathology plays an important role in predicting emotion recognition deficits and alexithymia in borderline, narcissistic, and histrionic personality disorders
Comparing the brain areas supporting attention to spatial arrangement and to temporal sequence in a working memory task
Left inferior parietal cortex integrates time and space during collision judgments
Left inferior parietal lobe lesions can cause perturbation of the space-time plans underlying skilled actions. But does the perceptual integration of spatiotemporal information use the same neural substrate or is the role of the left inferior parietal cortex restricted to visuomotor transformations? We use fMRI and a collision judgment paradigm to examine whether the left inferior parietal cortex integrates temporal and spatial variables in situations in which no complex action and no visuomotor transformation is required. We used a perceptual task in which healthy subjects indicated by simple button presses whether two moving objects (of the same or different size) would or would not collide with each other. This task of interest was contrasted with a control task that employed the same stimuli and identical motor responses but in which the size of the two moving objects had to be compared. To assess putative differential eye-movement effects both tasks were performed with and without central fixation. Analysis of the fMRI data (employing a random-effects model and SPM99) showed that collision judgments (relative to size judgments) provoked a significant increase in neural activity in the left inferior parietal cortex (supramarginal gyrus) only. These results show that left inferior parietal cortex is involved in the integration of perceptual spatiotemporal information and thus provide a neural correlate for the use of space-time plans (whose perturbation can lead to apraxia as originally hypothesized by Liepmann). Furthermore, the data suggest that the left supramarginal gyrus combines temporal and spatial variables more widely than previously supposed. (C) 2003 Elsevier Inc. All rights reserved
- …