1,911 research outputs found
On The Center Sets and Center Numbers of Some Graph Classes
For a set of vertices and the vertex in a connected graph ,
is called the -eccentricity of in
. The set of vertices with minimum -eccentricity is called the -center
of . Any set of vertices of such that is an -center for some
set of vertices of is called a center set. We identify the center sets
of certain classes of graphs namely, Block graphs, , , wheel
graphs, odd cycles and symmetric even graphs and enumerate them for many of
these graph classes. We also introduce the concept of center number which is
defined as the number of distinct center sets of a graph and determine the
center number of some graph classes
Autonomous Robot Path Planning in Static and Dynamic Environment by Applying Nature Inspired Computing (NIC) Algorithm
The mobile robot path planning is a central problem in several areas such as modern industry and cyber physical systems. This requires an embedding intelligence into that robotics for ensuring feasible solutions to task execution. Most of Research Problems are solved by observing the nature to solve our real-life day-to-day problems. The logic behind computing algorithms is inspired by nature for solving idea of computations problems. These algorithms are best optimization problems to solve computational problems in a reasonable time and providing optimum results. Path planning is one of the tasks of mobile robot to reach towards destination without any disturbance for reaching their goal within time bound. In this paper, the particle swarm optimization (PSO) is applied for mobile robot path planning to reach its destination. The performance results of proposed PSO for mobile robot path planning shows better results with conventional algorithms to reach destination with minimum energy consumption and also with minimize efficiency towards travelling from source to destination path
The Expectation Disconfirmation Theory of Green Banking Practices of State Bank of India with special reference to Kerala - A Structural Equation Modeling Approach
In light of Agenda 2030, sustainability awareness is steadily growing worldwide. All institutions, including banks and financial institutions, are working to reduce their carbon footprints. Several indirect problems have arisen for India as a result of the banking process, such as global warming, climate change, irregular monsoon, air pollution, heavy rain, poor air quality, health problems, ozone depletion, fossil fuel use, recurrent destruction of forests for daily use, improper e-waste disposal. These issues can be overcome with sustainable banking practices (Green banking), which benefit the customer's satisfaction and quality of life. However, sustainability can be achieved only when the customers accept green banking and are satisfied with it. In order to do that, the bank must understand the level of expectations and perception of its customers toward green initiatives and to what extent the initiatives satisfy their day-to-day needs. This paper provides an overview of Expectancy disconfirmation integrations into customer satisfaction of India's largest public sector banks. As part of the present theoretical analysis, we first examine the level of awareness, expectations, and perception differences of customers to determine their satisfaction level. We then provide some evidence from SBI in Kerala regarding dissatisfying factors in green banking practices
Effect of osmotic stress on in vitro plant growth hormone production by osmotolerant bacteria isolated from chilli phyto microbiome
The present study was conducted to determine the effect of osmotic stress on the plant growth hormone production by six osmotolerant plant growth promoting bacterial strains. These strains originated from the phytomicrobiome of chilli cultivated in the drought prone areas of Andhra Pradesh. They possessed multiple plant growth promotion traits including the ability to produce a variety of plant growth hormones. The effect of osmotic stress on the plant growth hormone production was determined by High Performance Liquid Chromatography (HPLC) under normal and in vitro osmotic stress conditions using 25% Poly Ethylene Glycol (PEG) 8000. In general, it was observed that osmotic stress impacted the plant growth hormone production of the isolates, but nevertheless plant hormones were detected in all the bacterial strains. An exception to this was the cytokinin molecule zeatin riboside, which was produced at higher levels by five of the six bacterial isolates under osmotic stressed conditions
Effect of osmotic stress on in vitro plant growth hormone production by osmotolerant bacteria isolated from chilli phyto microbiome
The present study was conducted to determine the effect of osmotic stress on the plant growth hormone production by six osmotolerant plant growth promoting bacterial strains. These strains originated from the phytomicrobiome of chilli cultivated in the drought prone areas of Andhra Pradesh. They possessed multiple plant growth promotion traits including the ability to produce a variety of plant growth hormones. The effect of osmotic stress on the plant growth hormone production was determined by High Performance Liquid Chromatography (HPLC) under normal and in vitro osmotic stress conditions using 25% Poly Ethylene Glycol (PEG) 8000. In general, it was observed that osmotic stress impacted the plant growth hormone production of the isolates, but nevertheless plant hormones were detected in all the bacterial strains. An exception to this was the cytokinin molecule zeatin riboside, which was produced at higher levels by five of the six bacterial isolates under osmotic stressed conditions
Method Development and Validation for the Simultaneous Estimation of Cefuroxime Axetil and Linezolid in Pharmaceutical Dosage form by RP-HPLC and HPTLC Method
INTRODUCTION: Analytical Chemistry is defined as âThe science and the art of determining
the composition of materials in terms of the elements or compounds contained.â
This branch of chemistry, which deals with both theoretical, practical science and
practiced in a large number of laboratories in many diverse ways. Methods of
analysis are routinely developed, improved, validated, collaboratively studied and
applied. In analytical chemistry it is of prime importance to gain information about
the qualitative and quantitative composition of substances and chemical species
that is to find out what substance is composed and exactly how much. In
quantitative analysis the question is how much is present. The research work in
this thesis is based on this criterion. Pharmaceutical analysis deals not only with
medicaments (drugs and their formulations) but also with their precursors i.e. with
the raw material on which degree of purity and quality of medicament depends.
The quality of the drug is determined after establishing its authenticity by testing
its purity and the quality of pure substance in the drug and its formulations.
Quality is important in every product or service but it is vital in medicine as it
involves life. Unlike ordinary consumer goods there can be no âsecond qualityâ in
drugs. Quality control is a concept, which strives to produce a perfect product by
series of measures designed to prevent and eliminate errors at different stages of
production. AIM AND OBJECTIVE: As per the literature review, there is no analytical methods reported for the
Hence,there is a need for suitable RP-HPLC and HPTLC Method for routine
analysis of Cefuroxime axetil and Linezolid in the combined formulation.
The work was an attempts to develop simple, rapid, and sensitive analytical
methods for the simultaneous estimation of Cefuroxime axetil and Linezolid in the
combined formulation in accordance with ICH Q2B guidelines and to extend the
method for routine analysis.
method for the simultaneous estimation of Cefuroxime axetil and Linezolid in the
combined tablet dosage form by RP-HPLC and HPTLC method.
STEP-1: Study of physiochemical properties of the drug
STEP-2: Selection of chromatographic condition
RVS College of Pharmaceutical Sciences Page 32
estimation of Cefuroxime axetil and Linezolid in combined pharmaceutical dosage
form by HPTLC. Various publications are available regarding the UV simultaneous
estimation and RP-HPLC method development of Cefuroxime axetil and Linezolid,
either alone or in combination with other drugs in pharmaceutical dosage form. RESULT AND DISCUSSION OF HPLC METHOD: Present report in this thesis is aimed at new analytical method development
for the simultaneous estimation of Cefuroxime axetil and Linezolid by RP-HPLC
method. From the literature review it was found that there was no single method for
the simultaneous estimation of Cefuroxime axetil and Linezolid by RP-HPLC
method. Hence new analytical method has been developed for the simultaneous
estimation of Cefuroxime axetil and Linezolid by RP-HPLC method and validated
according to ICH Q2B guidelines. CONCLUSION: A new method of analysis is developed for simultaneous estimation of
Cefuroxime axetil and Linezolid drugs in pharmaceutical tablet dosage form by RPHPLC
and HPTLC method. The analytical procedure is validated as per ICH Q2B
guidelines and shown to be simple,accurate, precise and specific. For routine
analytical purpose it is desirable to establish methods capable of analyzing huge
number of samples in a short time period with good robustness, accuracy and
precision without any prior separation step. HPLC and HPTLC method generates
large amount of quality data, which serve as highly powerful and convenient
analytical tool.
Cefuroxime axetil was freely soluble in ethanol, methanol, acetonitrile and
insoluble in water. Linezolid was soluble in chloroform, alcohol and insoluble in ether.
acetonitrile. and phosphate buffer was chosen as the mobile phase. The run time of
the HPLC procedure was 10 minutes. The method was validated for system
suitability, linearity, precision, accuracy, specificity, ruggedness robustness, LOD and
LOQ. The system suitability parameters were within limit, hence it was concluded that
the system was suitable to perform the assay. The method shows linearity between
the concentration range of 10-50ÎŒg / ml. The % recovery of Cefuroxime axetil and
Linezolid was found to be in the range of 99.22 % - 100.11 %. As there was no
interference due to excipients and mobile phase, the method was found to be
specific. The method was robust and rugged as observed from insignificant variation
in the results of analysis by changes in flow rate and mobile phase composition separately and analysis being performed by different analysts. Good agreement was
seen in the assay results of Pharmaceutical formulation by developed method.
Hence, it can be concluded that the proposed methods using HPLC and
HPTLC can be regarded as simple, fast reproducible and sensitive methods for the
simultaneous estimation of Cefuroxime axetil and Linezolid in combined dosage
form. Hence, these methods can be used for the in process evaluation in
Pharmaceutical Manufacturing Firms and routine quality control of these drugs in
Drug Testing Laboratories
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